• Korean Journal of Plant Taxonomy
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• v.41 no.2
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• pp.164-170
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• 2011

Two naturalized plants (Euphorbiaceae) were recorded from Busan Metropolitan City and from the Jeju Special Self-Governing Province. Euphorbia heterophylla L. (A-me-ri-ka-dae-geuk) was found in a park near Suyeong-gang, Allak-dong, Dongnae-gu, in Busan Metropolitan City. This species is distinguished from E. dentata by its alternating leaves of main stem and glands of involucres with a circular opening. Euphorbia hirta L. (Teol-ttang-bin-dae) was found in Yerae village, Yerae-dong, Seogwipo-si, in Jeju Special Self-Governing Province. It is distinguished from E. hypericifolia as it has capsules with hairs.

• Journal of Life Science
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• v.28 no.4
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• pp.454-464
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• 2018

Black soybeans are used as food sources as well as for traditional medicines because they contain an abundance of natural phenolic compounds. In this study, total phenolic contents (TPCs) of Korean black seed coat soybean varieties Socheongja (SCJ), Socheong 2 (SC2) and Cheongja 2 (CJ2) as well as their antioxidant capacities were investigated. Among them, TPCs were abundantly present in the order of CJ2$H_2O_2$-stimulated HaCaT human keratinocytes. Our results revealed that treatment with SCJ and SC2 prior to $H_2O_2$ exposure significantly increases the viability of HaCaT cells, indicating that the exposure of HaCaT cells to SCJ and SC2 conferred a protective effect against oxidative stress. SCJ and SC2 also effectively inhibited $H_2O_2$-induced apoptotic cell death through the blocking of mitochondrial dysfunction. SCJ and SC2 also attenuated the phosphorylation of Histone H2AX. Furthermore, they effectively induced the levels of thioredoxin reductase (TrxR) 1, a potent antioxidant enzyme, which is associated with the induction of nuclear transcription factor erythroid-2-like factor 2 (Nrf2); however, the protective effects of SCJ and SC2 were significantly reversed by Auranofin, a TrxR inhibitor. These results indicate that they have protective activity through the blocking of cellular damage related to oxidative stress via the Nrf2 signaling pathway. In conclusion, our study indicated that SCJ and SC2 might potentially serve as novel agents for the treatment and prevention of skin disorders caused by oxidative stress.