• The Journal of the Korea Contents Association
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• v.14 no.10
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• pp.628-638
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• 2014

The aim of this study was to explore the reliability and validity of the Korean version of the Recovery Assessment Scale in psychiatric patients. The original RAS was translated into Korean and the content was verified through back-translation procedures. This study included 142 patients who had chronic mental illness and were aged 18 or older. The subjects were assessed by using RAS-K, the 12-item Dispositional Hope Scale(DHS), the 28-item Mental Health Recovery Measure(MHRM), the 32-item Behavior and Symptom Identification Scale (BASIS-32). In the reliability test, Crobach's a coefficient and test-retest reliabilities were 0.92 and 0.79, respectively, indicating that the RAS-K has good internal consistency. In the analysis of the concurrent validity of the RAS-K, there were significant correlations between the RAS-K and DHS(r=.675, p<0.01), and between the RAS-K and MHRM(r=.816, p<0.01), but lower correlations with symptoms and clinician-related measures of psychiatric functioning. Factor analysis resulted in a five factor solution accounting for 62.476% of the common variance. Our study indicates that the RAS-K is an appropriate instrument to assess recovery in Korean psychiatric patients.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.9 no.4
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• pp.437-440
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• 1999

New method of control based upon a physical model of the Stepanov growth technique has been developed. The controller keeps the system stable and completely denies operator's interference into the process. The system demonstrates very reliable results under commercial production of shaped sapphire crystals.

• Toxicological Research
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• v.14 no.4
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• pp.569-575
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• 1998

One of the most frequent dejects in human cancer is the uncontrolled activation of the ms-signaling pathways. Significant evidence has accumulated to directly implicate members of the matrix metalloproteinases (MMPs) in tumor invasion and metastasis formation. We have previously shown that MMP-9 expression was significantly enhanced in the ras-tranfected HT1080 human fibrosarcoma cells at the mRNA level. In the present study, we investigated the roles of MMP-2 and -9 on the H-ras-induced invasive phenotypes of MCF 10A human breast epithelial cells and HT 1080 human fibrosarcoma cells. We show that H-ras is able to induce or enhance a signaling pathway leading to the enhancement of an invasive phenotype in both MCF10A and HT1080 cells as determined by matrigel invasion assay. We then examined the effect of H-ras activation on the expression of MMP-2 and -9 by measuring enzymatic activities and mRNA levels. Our data clearly demonstrated that H-ras prominently induces expression of MMP-2 in MCF10A cells, while it efficiently up regulates MMP-9 in HT1080 cells. Taken together, these findings suggest that the correlation between ras-mediated invasiveness and enhanced expression of MMPs may be cell type-specific: MMP-9 is closely associated with the invasive phenotype induced by ras activation in fibrosarcoma cells, whereas MMP-2 is more likely associated with it in epithelial cells.

• Journal of the Korean GEO-environmental Society
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• v.17 no.9
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• pp.21-28
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• 2016

The purpose of this study is to compare the three areas that each estimated by using three different river topographic maps. For construction of river topographic maps, the data used in this study are ASTER, SRTM and a 1:5,000 scale digital map data sets in 14 streams of the Cheongdo-gun and Uiseong-gun. HEC-GeoRAS, RAS Mapper, and RiverCAD model are applied for the flooding area analysis using observed data and design rainfalls. The result of analysis is to compare observed flooding area based on the flood plain maps with estimated inundation area by hydraulic models and constructed river topographic maps. The results of this study are as follows; Flooding area by HEC-GeoRAS model is similar to the inundation area of flood plain map and appears in order of RAS Mapper, and RiverCAD model in all watersheds. Flood inundation area by SRTM DEM is similar to the result of 1:5,000 scale digital map in all watersheds and all analysis models. The SRTM DEM shows the most similarity to the digital map than ASTER DEM in all of the watershed scale and analysis models. HEC-GeoRAS and RiverCAD model are efficient models for flood inundation analysis in small watershed and HEC-GeoRAS and Ras Mapper model are efficient in medium to large watershed.

• Membrane and Water Treatment
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• v.9 no.2
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• pp.123-128
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• 2018

Common aquaculture practices include the use of certain pharmaceuticals such as antibiotics in avoiding diseases and promoting a healthier growth of the culture. The aim of this study is to monitor and assess the influence of different low oxytetracycline concentrations on the transformation of nitrogen compounds under aeration condition in a lab-scale recirculating aquaculture system (RAS). Over $1mg\;L^{-1}$ dose of oxytetracycline to aquaculture had induced ammonia($NH_4-N$), nitrate($NO_3-N$), soluble COD accumulation in RAS. In addition, nitrous oxide ($N_2O$) emission from RAS was significantly reduced during the oxytetracycline dose periods. After ceasing the dose of oxytetracycline, ammonia oxidation and nitrous oxide re-emission were observed. This observation indicated that low concentrations of oxytetracycline could affect the nitrogen species in RAS. Also, the emission mechanisms of $N_2O$ may not be only dependent on nitrification process but also dependent on denitrification process in our RAS system.

• BMB Reports
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• v.36 no.4
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• pp.399-402
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• 2003

Early detection of bladder cancer is particularly important since it dramatically affects the survival rates. However, neither urinary cytology nor tumor markers that are currently used are sensitive enough for the early detection of bladder cancer or recurrent disease. The ras genes are frequently mutated in cancer. In this study, we investigated the diagnostic potential of ras mutation analysis in urinary sediments of patients with bladder cancer using a single-strand conformation polymorphism analysis and polymerase chain reaction. Mutation in codon 12 of the H-ras gene was observed in 39% of the patients. Our results indicate that this approach may significantly improve diagnostic sensitivity in detecting bladder tumors.

• Journal of the Korean Society of Food Science and Nutrition
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• v.21 no.3
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• pp.314-318
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• 1992

The sarcoma 180 cells were treated with ursolic acid which was previously extracted from leaves of Eriobotrya japonica Lindy (Rosaceae) and identified as a potent anticarinogenic agent. Suppressing effects of the compounds with testing changes in selected oncogenes expression were examined by using the northern hybridization method. Ursolic acid significantly suppressed c-myc oncogene expression. However, c-ha-ras oncogene expression was lowered slightly with the ursolic acid treatment. Therefore, it was concluded that preproven anticarcinogenic effects of ursolic acid should be partly ascribed to the modified oncogenic expression.

• Journal of Advanced Navigation Technology
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• v.10 no.1
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• pp.70-78
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• 2006

This paper has addressed the scheme to design single rate Rate Adaptive Shaper (srRAS) proposed in RFC2963. srRAS is the shaper used in conjugation with downstream single rate Three Color Marker (srTCM) described in RFC269. it is tail-drop First Input First Out (FIFO) queue that is drained at a variable rate. srTCM meters IP packet streams from srRAS and marks its packets to be either green, yellow, or red. This shaper has been proposed to use at the ingress of differentiated services networks providing AF PHB. And then srRAS can reduce the burstiness of the upstream traffic of srTCM. This paper addresses algorithm, architecture of srRAS, and the scheme to implement srRAS using Field-Programmable Gate Arrays (FPGA) and the related technology.

• Journal of Microbiology
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• v.34 no.2
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• pp.158-165
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• 1996

The signal transduction pathways through the RAS gene product and adenyl cyclease play a critical role in regulation of the cell cycle in yeast, Saccharomyces cerevisiae. We examined the genetic relationship between the spt3 gene and ras/cAMP pathway. A mutation in the SPT3 gene suppressed cell cycle arrest at the G1 phase caused by either an inactivation of the RAS or CYR1 gene which encodes a yeast homologue of human ras proto-oncogene or adenyl cyclase, respectively. The phenotypes such as sporulation and heat shock resistancy, that resulted from a partial inactivation of the RAS or CYR1 genes, were also suppressed by the spt3 mutation. Expression of the SSA1 gene encoding one of th heat shock proteins (Hsp70) can be induced by heat shock or nitrogen starvation. Expression of this gene is derepressed in cry1-2 and spt3 mutants. The bcy 1 mutation repressed by the bcy1 mutation, but not in spt3 mutants. These results suggest that the SPT gene is involved in expression of genes that are affected by the RAS/cAMP pathway.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2007.12a
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• pp.226-227
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• 2007

Significant increase of container flows in marine terminals requires more efficient automatic port systems. This paper presents a novel routing and collision avoidance algorithm of linear motor based shuttle cars using random access sequence dynamic programming (RAS DP). The proposed RAS DP is accomplished online for determining optimal paths for each shuttle car.