• Proceedings of the KIEE Conference
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• summer
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• pp.260-262
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• 2004

In recent years, both utilities and users have expressed their deep concerns about the quality of electric power. The harmonic is the one of power quality disturbance, it can raise a problem on the power system. In this paper, the increasing application of power electronic equipment [especially (ASDs adjustable speed drives)] on distribution systems has led to a growing concern for harmonic distortion and the resulting impacts on system equipment and operations. The purpose of this study is to calculate the quantity of harmonic voltage by varying the RECT side ASD load and to design the optimal harmonic filter for the elimination of harmonics.

• Proceedings of the KIEE Conference
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• 2007.11b
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• pp.243-245
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• 2007

There are some rebate programs for energy efficient appliances, which are lightings, vending machines, ASDs, motors, transformers, pumps, to reduce national energy consumption in Korea. Among these appliances, motors are of the essential target in the programs because these take about 64% of electrical energy consumption nationally. In this paper reasonable rebate levels are proposed using an advanced diffusion model and avoided cost analyses.

• Proceedings of the KIEE Conference
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• 2001.07b
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• pp.660-662
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• 2001

This paper describes the problems generated with the use of PWM ASDs with induction motors. The major effect of harmonic voltages and currents in induction motors is increased the heating due to iron and copper losses at harmonic frequencies. The harmonic components thus affect the motor efficiency and developed the torque. In order to investigate the effect of harmonics which is caused by using of nonlinear load at the low voltage system, we set up simple load system and measured the voltage and current. Measurement results show that additional operation of induction motor at the parallel bus in using nonlinear load such as ASD is helpful to the reduction of harmonic current.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.527-528
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• 2007

There are some rebate programs for energy efficient appliances, which are lightings, vending machines, ASDs, motors, transformers, pumps, to reduce national energy consumption in Korea. In existing studies, some diffusion models have been applied to the rebate program case. But those studies could not consider various cases in duration, amounts, whether or not, of rebates. Hence, new diffusion models considering the time-variant diffusion status are proposed for high-efficient appliance rebate programs in this paper. The case study shows the application of these model into some high-efficient appliances.

• Proceedings of the KIEE Conference
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• 2002.06a
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• pp.16-21
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• 2002

Most adjustable-speed drives(ASDs) designed to operate 220[V] induction motors incorporate voltage-source inverters (VSIs), which create motor voltages at high switching frequencies. The motor leads used to connect an ASD to a motor can behave like transmission lines for voltage pulses, which can be amplified (reflected) at the motor terminals. The resulting oscillatory transient, known as the long-lead effect, can stress and consequently degrade the statorinsulation system of a motor. This Brief describes the results of tests to 1) determine the correlation between peak motor voltage and the length of motor leads and 2) determine the correlation between peak motor voltage and the switching frequency of the ASD Insulation failures like this usually are caused by voltage surges. Voltage surges are often the result of switching power circuits, lightning strikes, capacitor discharges and solid-state power devices.

• Proceedings of the KIEE Conference
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• 2001.07e
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• pp.13-16
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• 2001

This paper describes the problems associated with the use of PWM ASDs to drive induction motors. A major effect of harmonic voltages and currents in induction motors is increased heating due to iron and copper losses at harmonic frequencies. The harmonic components thus affect the motor efficiency, and can also affect the torque developed. In order to investigate the effect of harmonics which is caused by using of nonlinear load at the low voltage system, we fixed up simple load model and measured the voltage and current. Measurement. results show that additional operation of linear load at the parallel bus in using nonlinear load such as ASD is helpful to the reduction of harmonic current.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.26 no.4
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• pp.273-278
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• 2015

Objectives : We retrospectively investigated the efficacy and tolerability of risperidone monotherapy in subjects with autism spectrum disorder (ASD). In addition, we did mixed effect model analysis of the effects of risperidone in patients with ASDs naturalistically treated in a routine clinical setting to determine whether the clinical effects were maintained and the side effects were tolerable. Methods : This retrospective study assessed children and adolescents with ASD, who were on risperidone monotherapy from July 2010 to July 2011 at the Child and Adolescent ASD Clinic at Seoul National Hospital. Outcome measures included the Clinical Global Impression-Severity of Illness (CGI-S) and the CGI-Improvement (CGI-I) scales along with other clinical indices: dosage, target symptoms, and side effects. Results : The mean dose of risperidone in 47 children and adolescents with ASD (40 males, 7 females; age range 5-19 years) who were on risperidone monotherapy was $1.6{\pm}0.8mg/day$, and the mean duration of the treatment period was $20.2{\pm}17.3months$. Aggressive behavior, stereotypic behavior, irritability, and self-injurious behavior were the most frequent target symptoms of risperidone. The most common side effects were weight gain followed by somnolence and extrapyramidal symptoms. In a mixed effects model analysis of CGI-I scores, the mean CGI-I score at the 1 month follow-up was significantly different from the mean CGI-I score of the 3-month follow-up (p=.046), and the CGI-I scores were equally maintained over 3 to 48 months [F(6, 28.9)=4.393, p=.003]. Of the 47 patients, 33 patients (70.2%) were identified as the response group, showing an end point CGI-I rating of 3 or under and having continued risperidone treatment for at least 6 months. The baseline CGI-S score showed significant association with clinical response to risperidone (p=.005), the mean baseline CGI-S was higher in the response group compared to the non-response group. Conclusion : In this study, clinical improvement of risperidone stabilized around 3 months and was equally maintained up to 48 months with tolerable side effects, supporting maintenance of risperidone treatment in children and adolescents with ASDs.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.330-335
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• 2001

While contacting directly with ground, the tire tread part is in shape of complex patterns of variable ASDs(anti-skid depth) for various tire performances. However, owing to the painstaking mesh generation job and the extremely long CPU-time, conventional 3-D tire analyses have been performed by either neglecting tread pattern or modeling circumferential grooves only. As a result, such simplified analysis models lead to considerably poor numerical expectations. This paper addresses the development of a systematic 3-D mesh generation of tires considering the detailed tread pattern. Basically, tire body and tread meshes are separately generated, and then both are to be combined. For the systematic mesh generation, which consists of a series of meshing steps, we develop in-house subroutines which utilize the useful functions of I-DEAS solid modeler. The detailed pattern mesh can be imparted partially or completely.

• Genomics & Informatics
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• v.8 no.1
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• pp.19-27
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• 2010

To discover genetic markers for autism spectrum disorder (ASD), we previously applied genome-wide BAC array comparative genomic hybridization (array-CGH) to 28 autistic patients and 62 normal controls in Korean population, and identified that chromosomal losses on 8p23.1 and on 17p11.2 are significantly associated with autism. In this study, we developed an 8.5K ASD-specific BAC array covering 27 previously reported ASD-associated CNV loci including ours and examined whether the associations would be replicated in 8 ASD patient cell lines of four different ethnic groups and 10 Korean normal controls. As a result, a CNV-loss on 8p23.1 was found to be significantly more frequent in patients regardless of ethnicity (p<0.0001). This CNV region contains two coding genes, DEFA1 and DEFA3, which are members of DEFENSIN gene family. Two other CNVs on 17p11.2 and Xp22.31 were also distributed differently between ASDs and controls, but not significant (p=0.069 and 0.092, respectively). All the other loci did not show significant association. When these evidences are considered, the association between ASD and CNV of DEFENSIN gene seems worthy of further exploration to elucidate the pathogenesis of ASD. Validation studies with a larger sample size will be required to verify its biological implication.

• Journal of Korean Neurosurgical Society
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• v.42 no.3
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• pp.184-190
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• 2007

Objective : The authors retrospectively analyzed clinical and radiographic features of patients who developed symptomatic adjacent segment degeneration (ASD) that required re-operation. Methods : From 1995 to 2004, among 412 patients who underwent posterior lumbar fusion surgery, the authors experienced twenty-six patients who presented symptomatic ASD. Records of these patients were reviewed to collect clinical data at the first and second operations. Results : The patients were 9 males and 17 females whose mean age was $63.5{\pm}8.7$ years. Among 319 one segment and 102 multi-segment fusions, 16 and 10 patients presented ASD, respectively. Seventeen ASDs were noticed at the cephalad to fusion (65%), eight at the caudad (31%), and one at the cephalad and caudad, simultaneously (4%). All patients underwent decompression surgery. Nine patients underwent additional fusion surgeries to adjacent degenerated segments. In 17 patients who underwent only decompression surgery without fusion, the success rate was 82.4%. In fusion cases. the success rate was observed as 55.5%. There were no statistically significant factors to be related to development of ASD. However, in cases of multi-level fusion surgery, there was a tendency toward increasing ASD. Conclusion : Multi-segment fusion surgery could be associated with a development of ASD. In surgical treatment of symptomatic ASD, selective decompression without fusion may need to be considered as a primary procedure, which could reduce the potential risk of later occurrence of the other adjacent segment disease.