A sequence of earthquakes with the main shock $M_L$ 5.8 occurred on September 12 2016 in the Gyeongju area. The main shock was the largest earthquakes in the southern part of the Korean peninsula since the instrumental seismic observation began in the peninsula in 1905 and clearly demonstrated that the Yangsan fault is seismically active. The mean focal depth of the foreshock, main shock, and aftershock of the Gyeongju earthquakes estimated by the crustal model of single layer of the Korean peninsula without the Conrad discontinuity turns out to be 12.9 km, which is 2.8 km lower than that estimated based on the IASP91 reference model with the Conrad discontinuity. The distribution of the historical and instrumental earthquakes in the Gyeongju area indicates that the Yangsan fault system comprising the main Yangsan fault and its subsidiary faults is a large fracture zone. The epicenters of the Gyeongju earthquakes show that a few faults of the Yangsan fault system are involved in the release of the strain energy accumulated in the area. That the major earthquakes of Gyeongju earthquakes occurred not on the surface but below 10 km depth suggests the necessity of the study of the distribution of deep active faults of the Yangsan fault system. The magnitude of maximum earthquake of the Gyeongju area estimated based on the earthquake data of the area turns out to be 7.3. The recurrence intervals of the earthquakes over magnitudes 5.0, 6.0 and 7.0 based on the earthquake data since 1978, which is the most complete data in the peninsula, are estimated as 80, 670, and 5,900 years, respectively. The September 2016 Gyeongju earthquakes are basically intraplate earthquakes not related to the Great East Japan earthquake of March 11 2011 which is interplate earthquake.
The cracking resistance of asphalt mixtures is generally evaluated by measuring a single parameter (i.e., Tensile strength, Stiffness). However, the use of a single parameter has been questioned in the evaluation of asphalt mixture cracking performance. The focus of this study was to clearly identify the key properties and characteristics associated with the cracking resistance of asphalt mixtures. Results of fracture, creep, and strength tests at multiple loading rates performed on the modified and unmodified mixtures showed that the mixture cracking resistance was primarily affected by the rate of micro-damage accumulation. This was reflected in the m-value, without affecting the fracture energy limit. It was also observed that the short loading time (elastic) stiffness alone could not differentiate the mixture cracking resistance of the mixtures. It was concluded that the key to characterize the cracking resistance of asphalt mixture is in the evaluation of the combined effects of creep and failure limits. It was also found that a residual dissipated energy parameter measured from Superpave IDT strength test gave the quick and useful way to distinguish the difference of cracking resistance of asphalt mixtures. Failure strain in the longer-term creep test appeared to be a useful parameter for evaluating the combined effects of creep and failure limits of asphalt mixtures.
Journal of the Korean Society for Nondestructive Testing
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v.24
no.3
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pp.259-267
/
2004
A finite element method is used to simulate interaction of laser-based ultrasounds with surface breaking tracks in elastic media. The laser line source focused on the surface of semi-infinite medium is modeled as a shear dipole in 2-D plane strain finite elements. The shear dipole-finite clement model is found to give correct directivity patterns for generated longitudinal and shear waves. The interaction of surface waves with surface breaking cracks (2-D machined slot) is considered in two ways. Both the source and receiver are fixed with respect to the cracks in the first case, while the source is moving in another case. It is shown that the crack depth tested in the range of 0.3-5.0mm $({\lambda}_R/d=0.21{\sim}3.45)$ can be measured using the corner reflected waves produced by the fixed laser source. The moving laser source is found to cause a large amplitude change of reflected waves near crack, and the crack whose depth is one order lower than the wavelength ran be detected from this change.
Little information is available on the effects of low pH on nodulation and growth of subterranean clover cultivars. Plants of 11 cultivars were inoculated with an acid-tolerant strain of Rhizobium trifolii and grown for 28 days in continuously flowing nitrogen-free nutrient solutions maintained at six constant pH values from 4.0 to 6.5. At pH 4.0, 4 cultivars failed to nodulate and the remainder formed only a few nodules; nodulation was delayed by 2 to 3 days in this treatment. All cultivars nodulated at pH 4.5 but, with the exception of cv. Dwalganup, nodule numbers were significantly less than at $pH{\geq}5.0$. Only in cvv. Clare and Woogenellup were nodule numbers significantly greater at pH 6.5 than at 5.0. Whole plant dry matter yields were strongly depressed at pH 4.0(21 to 33% of maximum). At pH 4.5, relative yields of all cultivars except Dwalganup were significantly depressed without significant reductions in nodule dry weights, suggesting that nodule function was inhibited by acidity. These results are consistent with the view that nodulation and growth of plants dependent on symbiotic nitrogen fixation are much more sensitive to low pH per se than is host plant growth in the presence of adequate mineral nitrogen.
This research was investigated the effects of temperature and time against the formation of biofilms by foodborne pathogens on surfaces of polyethylene and stainless steel. After preliminary experiments with 32 strains from 6 species of foodborne pathogens (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella Typhimurium), one strain from each species with the highest biofilm formation efficiency was selected. All foodborne pathogens showed a tendency toward an increased ability for biofilm formation with increasing temperature, but there was no consistency between the two materials and between foodborne pathogens. At all tested temperatures, the biofilm formation ability of E. coli and P. aeruginosa on the polyethylene surface was higher than that on the stainless steel surface with significant differences. The foodborne pathogens all formed biofilms immediately upon inoculation, and biofilm formation by E. coli, P. aeruginosa, and S. Typhimurium increased on both the polyethylene and stainless steel surfaces at 1 h after inoculation compared to at 0 h. At 7 days after biofilm formation, the other strains except S. aureus showed no difference in survival rates on polyethylene and stainless steel. The ability of these 6 foodborne pathogens to form biofilms showed different trends depending on the type of bacteria and the instrument material, i.e., polyethylene and stainless steel.
Mohamed, Shereen H;Mahmoud, Nora F;Mohamed, Aly F;Kotb, Nahla S
Asian Pacific Journal of Cancer Prevention
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v.16
no.14
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pp.5635-5641
/
2015
Background: Cirrhosis is regarded as a possible end stage of many liver diseases, including viral infection. It occurs when healthy liver tissue becomes damaged and is replaced by scar tissue and finally may lead to hepatocellular carcinoma. Interferons (IFNs)are two general categories, type I and II. Type I includes one beta interferon and over 20 different alpha interferons. Alpha interferons are very similar in how they work, interacting with other proteins on cells like receptors. The main objective of this study was to compare Mx gene productivity post different cell line treatment with imported and Egyptian biosimilar locally produced IFNs, as well as the efficacy of those tested IFNs. Also, an assessment was made of sensitivity of different cell lines as alternatives to that recommended for evaluation of antiviral activity. Materials and Methods: Different cell lines (Vero, MDBK and Wish) were employed to evaluate cytotoxicity using the MTT assay. Antiviral activity was evaluated compared with standard IFN against VSV, Indiana strain -156, on tested rh-IFNs (imported; innovated and Egyptian biosimilar locally produced IFNs) in the pre-treated cell lines previously mentioned. The virus was propagated in the Wish cell line as recommended. Finally we estimated up-regulation of the Mx gene as a biomarker. Results: Data recorded revealed that test IFNs were safe in test cell lines. Viability was around 100%. Locally tested interferon did not realize the international potency limits, while the imported one was accepted compared with the standard IFN. These results were the same either using infectivity titer reduction assay or crystal violet staining of residual non- infected cells. Mx protein production was cell type related and confirmed by the detected Mx gene expressed in imported and locally produced IFN pre-treated cell lines. The expression of the gene was arranged in the order of Vero> wish > MDBK for the imported IFN, while for the Egyptian biosimillar locally produced one it was MDBK> Vero> wish. With regard to the antiviral activity there was a significant difference of imported IFN potency compared with the locally produced IFN (P<0.05), the IFN potential (antiviral activity) was not cell line related and showed non-significant difference for each separate product. Conclusions: Vero cells can be used as an alternative cell line for evaluation of IFN potency in case of unavailable USP recommended cell lines. Alternative potency evaluation assay could be used and proved significant difference in IFN potency in case of local and imported agents. Evaluation of antiviral activity could be used in parallel to viral infectivity reduction assay for better accuracy. Mx gene can be used as a marker for IFN potential.
KSCE Journal of Civil and Environmental Engineering Research
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v.35
no.2
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pp.275-285
/
2015
This experimental study presents the fatigue evaluation of a precast deck connected using Ultra-High Performance, Fiber Reinforced Concrete (UHPFRC). Four types of two identical large-scale specimens were fabricated with simplified splice rebar details which had a short splice length of ten times rebar diameter. The flexural behavior of each type of specimens until failure was investigated and fatigue behavior of the same type of specimens was then evaluated using two-million cyclic loading. In the flexural tests, tensile rebars exhibited the deformation exceeding yielding strain but failure mode related to the splice details was not observed in spite of such a short splice length. In the fatigue tests, damage was not appreciably accumulated by the cyclic loading except initial flexural cracks and the stress variations in tensile rebars was less than the allowable stress range. These experimental results demonstrate that all types of specimens exhibited acceptable fatigue performance and indicate that enhanced mechanical properties of ultra-high performance material permits to use a simplified splice details along with short joint width.
The variations of both thiamine and riboflavin value in the organs, viz. liver, small intestine, spleen and kidney of the rats were measured for observing some metabolic changes in the animals during fasting and feeding different quality of diets without V-E supplement. The animal used for the experiment was adult female ablino rat from a pure strain, weighing 225-280g. The animals were divided into 6 groups; the control group, the high carbohydrate diet group, the high carbohydrate diet with V-E group, the high protein diet group, the high protein diet with V-E group, and fasting group. The result obtained are summarized as follows; 1. The thiamine contents in the liver were once increased during early stage of starvation compared with the control group, thereafter they were decreased on the 8 days fasting while the contents in the small intestine and spleen were decreased during 1 to 8 days fasting. 2. The riboflavin contents in the liver and kidney were increased during starvation and the content in the small intestine was no marked change compared with control group. 3. The thiamine contents in the liver and small intestine during feeding the high carbohydrate with V-E supplement diet group were lower than that of the diet without V-E group and the content in the spleen was increased by feeding V-E enriched high carbohydrate diet. 4. The thiamine contents in the liver, small intestine and spleen during feeding the V-E supplemented diets were lower than that of the non-supplemented one's. 5. The riboflavin contents in the liver, small intestine, and kidney were increased during feeding the high carbohydrate diet compared to the control group, and they were decreased during feeding the V-E enriched high carbohydrate diet. 6. The riboflavin contents in each organ were increased during feeding the high protein diet compared to the control group, and they were much increased during 20 to 30 days of feeding the V-E supplemented high protein diet. 7. Therefore, as the above results showed, the variation of thiamine value in the each organs were not markedly changed during feeding different quality of the diets. The thiamine and riboflavin contents in the each organ in the V-E enriched high carbohydrate diet group were lower than without V-E supplemented one's The riboflavin contents in each organ were increased during feeding the high protein diet compared with the control group and the centents were increased during 20 to 30 days of the feeding V-E enriched high protein diet.
Vibrio vuln$cus has been recognized as a pathogen of septicemia and wound infection, when the organism attacks high-risk persons with a history of hepatic disease. alcohol abuse. diabetes or any debilitative disease. Forty six strains of K vulnzjicus. isolated from 1025 marine specimens from May to Novemver for three years. from 1985 to 1987. were studied for their biochemical properties. growth requirements, serotype and drug susceptibilities. The isolates were different in their various biochemical reactions. Ninety-five percent of isolated strains were able to ferment lactose, while most strains didn't utilize sucrose in their biochemical test, for example ornithine, gelatin and mannitol were quite dit'ferent composition than those described in other reports. It was found that the biochemical test wasn't useful for identifying strain. The type of somatic 0 antiserum was determined in isolates from marine sources and in patients with Vibrio septicemia. In patient isolates. 1-2 group were 24% and 1-4 group were 42%. However. 02 group(33%) were more abundant in isolates from marine sources. Minimal inhibitory concentrations(M1Cs) of chloramphenicol, tetracycline. erythromycin and ampicillin were determinef for V vuln~ficus by broth dilution method. MIC90 was I , 0.25, :! and 4,ug/ml in patient isolates. 1, 0.25, 2 and 2 ,ug/ml in marine isolates. The divalent chelating agent, IDTA. inhibited the growth of V. vuln!'ficus at 6.25 mMlml of MIC90.
Journal of the Korea Academia-Industrial cooperation Society
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v.17
no.8
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pp.62-68
/
2016
The feeder cable assembly is an automotive part used for telecommunication. If it malfunctions, the control and safety of the automobile can be put at risk. ALT (Accelerated Life Testing) is a testing process for products in which they are subjected to conditions (stress, strain, temperatures, etc.) in excess of their normal service parameters in an attempt to uncover faults and potential modes of failure in a short amount of time. Failure is caused by defects in the design, process, quality, or application of the part, and these defects are the underlying causes of failure or which initiate a process leading to failure. Thermal shock occurs when a thermal gradient causes different parts of an object to expand by different amounts. Thermal shock testing is performed to determine the ability of parts and components to withstand sudden changes in temperature. In this research, the main causes of failure of the feeder cable assembly were snapping, shorting and electro-pressure resistance failure. Using the Coffin-Manson model for ALT, the normal conditions were from Tmax = $80^{\circ}C$ to Tmin = $-40^{\circ}C$, the accelerated testing conditions were from Tmax = $120^{\circ}C$ to Tmin = $-60^{\circ}C$, the AF (Acceleration Factor) was 2.25 and the testing time was reduced from 1,000 cycles to 444 cycles. Using the Bxlife test, the number of samples was 5, the required life was B0.04%.10years, in the acceleration condition, 747 cycles were obtained. After the thermal shock test under different conditions, the feeder cable assembly was examined by a network analyzer and compared with the Weibull distribution modulus parameter. The results obtained showed good results in acceleration life test mode. For the same reliability rate, the testing time was decreased by a quarter using ALT.
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