• 제목/요약/키워드: Just-In-Time

검색결과 2,165건 처리시간 0.03초

Assessing Markov and Time Homogeneity Assumptions in Multi-state Models: Application in Patients with Gastric Cancer Undergoing Surgery in the Iran Cancer Institute

  • Zare, Ali;Mahmoodi, Mahmood;Mohammad, Kazem;Zeraati, Hojjat;Hosseini, Mostafa;Naieni, Kourosh Holakouie
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권1호
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    • pp.441-447
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    • 2014
  • Background: Multi-state models are appropriate for cancer studies such as gastrectomy which have high mortality statistics. These models can be used to better describe the natural disease process. But reaching that goal requires making assumptions like Markov and homogeneity with time. The present study aims to investigate these hypotheses. Materials and Methods: Data from 330 patients with gastric cancer undergoing surgery at Iran Cancer Institute from 1995 to 1999 were analyzed. To assess Markov assumption and time homogeneity in modeling transition rates among states of multi-state model, Cox-Snell residuals, Akaikie information criteria and Schoenfeld residuals were used, respectively. Results: The assessment of Markov assumption based on Cox-Snell residuals and Akaikie information criterion showed that Markov assumption was not held just for transition rate of relapse (state 1 ${\rightarrow}$ state 2) and for other transition rates - death hazard without relapse (state 1 ${\rightarrow}$ state 3) and death hazard with relapse (state 2 ${\rightarrow}$ state 3) - this assumption could also be made. Moreover, the assessment of time homogeneity assumption based on Schoenfeld residuals revealed that this assumption - regarding the general test and each of the variables in the model- was held just for relapse (state 1 ${\rightarrow}$ state 2) and death hazard with a relapse (state 2 ${\rightarrow}$ state 3). Conclusions: Most researchers take account of assumptions such as Markov and time homogeneity in modeling transition rates. These assumptions can make the multi-state model simpler but if these assumptions are not made, they will lead to incorrect inferences and improper fitting.

MODELS AND SOLUTION METHODS FOR SHORTEST PATHS IN A NETWORK WITH TIME-DEPENDENT FLOW SPEEDS

  • Sung, Ki-Seok;Bell, Michael G-H
    • Management Science and Financial Engineering
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    • 제4권2호
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    • pp.1-13
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    • 1998
  • The Shortest Path Problem in Time-dependent Networks, where the travel time of each link depends on the time interval, is not realistic since the model and its solution violate the Non-passing Property (NPP:often referred to as FIFO) of real phenomena. Furthermore, solving the problem needs much more computational and memory complexity than the general shortest path problem. A new model for Time-dependent Networks where the flow speeds of each link depend on time interval, is suggested. The model is more realistic since its solution maintains the NPP. Solving the problem needs just a little more computational complexity, and the same memory complexity, as the general shortest path problem. A solution algorithm modified from Dijkstra's label setting algorithm is presented. We extend this model to the problem of Minimum Expected Time Path in Time-dependent Stochastic Networks where flow speeds of each link change statistically on each time interval. A solution method using the Kth-shortest Path algorithm is presented.

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커튼월 공사의 적시생산(JIT)관리를 위한 양중 조달 시스템 개발방향에 관한 연구 (A Study on directions of Developing a Transportation and Procurement System for JIT Management of Curtain Walls in High-Rise Building Construction)

  • 양종엽;안병주;백종건;김재준
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2002년도 학술대회지
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    • pp.371-374
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    • 2002
  • 본 연구는 커튼월 공사의 적시생산(Just-In-Time; JIT) 관리를 지원할 수 있는 양중조달관리 시스템의 개발 방향의 제시를 목적으로 하고 있다. 이를 위해서 건설업에 있어서 적시생산의 개념을 살펴본 후, 커튼월 자재의 속성을 파악하고 현장과 문헌조사를 통하여 현장 물류관리의 문제점을 파악하였다. 이러한 문제점에 대한 해결방안으로서 본 연구에서는 커튼월 공사의 JIT 관리를 위한 양중 조달 시스템의 개발 방향을 제시하였다.

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자바 바이트코드로부터 JNI를 사용한 C 코드의 변환 (Translation of Java Bytecode into C code with the JNI)

  • 권혜은;김상훈
    • 정보학연구
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    • 제4권1호
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    • pp.1-7
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    • 2001
  • 자바 프로그램은 플랫폼 독립적이라는 장점을 갖는 반면에 그의 실행이 가상 기계를 통하여 이루어지기 때문에 실행 시간의 비효율성을 가진다. 이러한 문제를 극복하기 위해 just-in-time(JIT) 컴파일러, 오프라인 바이트코드 컴파일러와 같은 다양한 해결 방법이 제안되어 왔다. 그러나 JIT 컴파일러는 실행시간에 바이트코드로부터 네이티브 코드로의 번역이 일어나므로 실행시간 부담을 가진다. 그리고 순수 오프라인 바이트코드 컴파일러는 동적 클래스 적재(dynamic class loading)의 어려움을 가진다. 본 논문에서는 동적으로 바이트코드를 적재학 수 있는 능력을 유지하면서, JIT 보다 더 효율적 실행이 가능한 방법을 제안한다. 또한 기존의 bytecode-to-C 번역기와는 달리, 우리의 번역기는 자바 네이티브 인터페이스(JNI)를 사용함으로서 JDK 실행 환경과의 완벽한 호환성을 유지한다. 본 연구의 결과로 바이트코드를 JNI를 사용한 C 코드로 변환하기 위한 번역기를 설계하고 구현하였다.

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디지털 게임의 공간 표현 특성에 관한 연구 (A Study on Spacial Characteristic features in Digital Game)

  • 황용섭;김주연
    • 한국실내디자인학회논문집
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    • 제33호
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    • pp.3-10
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    • 2002
  • Virtual reality is not a new concept but just a new word and also it isnt limited to the reality created by computer-assisted image composition. Furthermore, we have lived within the virtual reality since long time ago, and the newly emerging digital technology has made the limits of the virtual expression vague and the definition of space concept new, The magical experiences we have had within the digital space consisted of Virtual space are the philosophical subject which we can hardly explain as a simple dichotomous definition such as Virtuality or Reality. But its true that our experiences made within virtual space are felt as much newer space considering those of space design, which have been traditionally made in our physical territory. Digital game is the representative space that provides a new space. Therefore, the new concept in space will be not just the territory expansion of space but also the opportunity we can find a new possibility through the relation between human and space. At this point in time that the life territory is expanding as a new space, this research goal is to show the new possibility of the connection of human and digital space through studying the relationship of Human and Space, Space and Digital space and Human and Digital space as well as The peculiarity of the space which is expressed at Digital game, the most representative space providing new experiences.

인삼(Panax ginseng C.A. Meyer) 잎의 생장과정에 따른 엽록체 미세구조 및 틸라코이드막 단백질의 변화 (Changes of Chloroplast Ultrastructure and Thylakoid Membrane Proteins during Growth of Ginseng (Panax ginseng C.A. Meyer) Leaf)

  • 안정숙;박훈;김우갑
    • Journal of Ginseng Research
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    • 제19권3호
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    • pp.275-280
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    • 1995
  • The formation of thylakoid membrane proteins and changes in the chloroplast ultrastructure of ginseng leaf were investigated as a function of time following the leaf emergence. The leaf chloroplast obtained just after the leaf emergence showed short rod-like thylakoids which were connected and arranged in 3~4 layers along the longitudinal axis of the chloroplast. The 10 DAE (days after emergence) chloroplast started to form grana structure. The typical grana structure was observed 17 DAE, and the grana was fully developed 28 DAE. The membrane proteins obtained from just after emerging leaf were separated into many minor bands indicating no CP-complex formation yet. LHC II was detected after 10 days. CP 47 and CP 43 were detected after 17 days. After 28 days, the PS I and PS II proteins were distinctly separated into CP 1, LHC II, CP 47, CP 43, CP 29, CP 27+24. Thus, the appearance of the light harvesting protein, LHC II, which was concentrated in grana stacks, was consis tent in time with the formation of grana stacks 17 DAE. Key words Chloroplast ultrastructure, grana, CP-complex, LHC II.

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고속 정밀 로봇 제어를 위한 실시간 중앙 집중식 소프트 모션 제어 시스템 (Real-Time Centralized Soft Motion Control System for High Speed and Precision Robot Control)

  • 정일균;김정훈
    • 대한임베디드공학회논문지
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    • 제8권6호
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    • pp.295-301
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    • 2013
  • In this paper, we propose a real-time centralized soft motion control system for high speed and precision robot control. The system engages EtherCAT as high speed industrial motion network to enable force based motion control in real-time and is composed of software-based master controller with PC and slave interface modules. Hard real-time control capacity is essential for high speed and precision robot control. To implement soft based real time control, The soft based master controller is designed using a real time kernel (RTX) and EtherCAT network, and servo processes are located in the master controller for centralized motion control. In the proposed system, slave interface modules just collect and transfer all sensor information of robot to the master controller via the EtherCAT network. It is proven by experimental results that the proposed soft motion control system has real time controllability enough to apply for various robot control systems.

Al/비정질 Se/Al구조에서의 암기력발생현상에 관한 연구 (A Study on Dark EMF Phenomena in Al/Amorphous Se/Al Structure)

  • 정홍배;신병규;이영종
    • 대한전기학회논문지
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    • 제32권6호
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    • pp.199-204
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    • 1983
  • In this paper, we investigated that the Al-Amorphous Se-Al structure had a large photovoltage and a Dark EMF (DEMF). This DEMF phenomena did not show just after the fabrication of a sample. However, it was shown after a few days, and it was increased with time, and was saturated after 30 days. Just after the fabrication of a sample, by appling the positive voltage on a sample for 100mins, we observed almost the same effect as had shown in a aging experiment. As the results, we found that Al3+ ions has related to a DEMF by migrating into amorphous Se, and form a trap in amorphous Se. We have also observed the photocapacitance effect to identify this trap formation.

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생산준비시간 단축과 생산로트사이즈에 대한 연구 (A Study on the Effect of Setup Time Reduction on Production Lot Sizes)

  • 구일섭;김진수
    • 산업경영시스템학회지
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    • 제17권32호
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    • pp.121-126
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    • 1994
  • Setup Time Reduction is an important aspect of the Just-in-Time(JIT) and Zero Inventory(Zl) Concepts since it supports reductions in manufacturing lead times and inventories. It also enables small lot sizes and kanban systems implementation for material flow - achieving major improvements in production floor management. One concept fundamental to the pursuit of JIT production in Japan and other countries is adoption of a setup time reduction. This paper looks at the necessities of setup time reduction and the relations to machine utilization. By using an EOQ model for evaluate the effect of setup time reduction, we get the results that over 75 % reduction in setup time is obtain the desired results in the lot size reduction.

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