• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.1
• /
• pp.441-447
• /
• 2014

Background: Multi-state models are appropriate for cancer studies such as gastrectomy which have high mortality statistics. These models can be used to better describe the natural disease process. But reaching that goal requires making assumptions like Markov and homogeneity with time. The present study aims to investigate these hypotheses. Materials and Methods: Data from 330 patients with gastric cancer undergoing surgery at Iran Cancer Institute from 1995 to 1999 were analyzed. To assess Markov assumption and time homogeneity in modeling transition rates among states of multi-state model, Cox-Snell residuals, Akaikie information criteria and Schoenfeld residuals were used, respectively. Results: The assessment of Markov assumption based on Cox-Snell residuals and Akaikie information criterion showed that Markov assumption was not held just for transition rate of relapse (state 1 ${\rightarrow}$ state 2) and for other transition rates - death hazard without relapse (state 1 ${\rightarrow}$ state 3) and death hazard with relapse (state 2 ${\rightarrow}$ state 3) - this assumption could also be made. Moreover, the assessment of time homogeneity assumption based on Schoenfeld residuals revealed that this assumption - regarding the general test and each of the variables in the model- was held just for relapse (state 1 ${\rightarrow}$ state 2) and death hazard with a relapse (state 2 ${\rightarrow}$ state 3). Conclusions: Most researchers take account of assumptions such as Markov and time homogeneity in modeling transition rates. These assumptions can make the multi-state model simpler but if these assumptions are not made, they will lead to incorrect inferences and improper fitting.

• Management Science and Financial Engineering
• /
• v.4 no.2
• /
• pp.1-13
• /
• 1998

The Shortest Path Problem in Time-dependent Networks, where the travel time of each link depends on the time interval, is not realistic since the model and its solution violate the Non-passing Property (NPP:often referred to as FIFO) of real phenomena. Furthermore, solving the problem needs much more computational and memory complexity than the general shortest path problem. A new model for Time-dependent Networks where the flow speeds of each link depend on time interval, is suggested. The model is more realistic since its solution maintains the NPP. Solving the problem needs just a little more computational complexity, and the same memory complexity, as the general shortest path problem. A solution algorithm modified from Dijkstra's label setting algorithm is presented. We extend this model to the problem of Minimum Expected Time Path in Time-dependent Stochastic Networks where flow speeds of each link change statistically on each time interval. A solution method using the Kth-shortest Path algorithm is presented.

• Proceedings of the Korean Institute Of Construction Engineering and Management
• /
• autumn
• /
• pp.371-374
• /
• 2002

Purpose of this study is to suggest the directions for development of a transportation and procurement system for JIT management of curtain walls. First, this study looks over the concept of JIT, and grasps the characteristics of the material and the problems of logistics in the construction field through the field and literature survey. And then, it develops countermeasures for the problems and with this, it suggests the directions for development of a transportation and procurement system for JIT management.

• The Journal of Information Technology
• /
• v.4 no.1
• /
• pp.1-7
• /
• 2001

The well-known tradeoff of Java's portability is the inefficiency of its basic execution model, which relies on the interpretation of an virtual machine. Many solutions have been proposed to overcome this problem, such as just-in-time(JIT) and offline bytecode compilers. However, JIT compiler can not avoid the overhead of runtime. since it translate bytecode into native code at runtime. And, pure offline bytecode compiler limits the ability of dynamic class loading. In this paper, we present an approach which preserves the ability to dynamically load bytecode, and is more efficient than JIT. In contrast to existing bytecode-to-C translator using the old NMI, our translator maintain complete compatibility and portability through using the Java Native Interface(JNI) standard. We have designed and implemented an translator for converting bytecode to C code with JNI.. named MyJNItool.

• Korean Institute of Interior Design Journal
• /
• no.33
• /
• pp.3-10
• /
• 2002

Virtual reality is not a new concept but just a new word and also it isnt limited to the reality created by computer-assisted image composition. Furthermore, we have lived within the virtual reality since long time ago, and the newly emerging digital technology has made the limits of the virtual expression vague and the definition of space concept new, The magical experiences we have had within the digital space consisted of Virtual space are the philosophical subject which we can hardly explain as a simple dichotomous definition such as Virtuality or Reality. But its true that our experiences made within virtual space are felt as much newer space considering those of space design, which have been traditionally made in our physical territory. Digital game is the representative space that provides a new space. Therefore, the new concept in space will be not just the territory expansion of space but also the opportunity we can find a new possibility through the relation between human and space. At this point in time that the life territory is expanding as a new space, this research goal is to show the new possibility of the connection of human and digital space through studying the relationship of Human and Space, Space and Digital space and Human and Digital space as well as The peculiarity of the space which is expressed at Digital game, the most representative space providing new experiences.

• Journal of Ginseng Research
• /
• v.19 no.3
• /
• pp.275-280
• /
• 1995

The formation of thylakoid membrane proteins and changes in the chloroplast ultrastructure of ginseng leaf were investigated as a function of time following the leaf emergence. The leaf chloroplast obtained just after the leaf emergence showed short rod-like thylakoids which were connected and arranged in 3~4 layers along the longitudinal axis of the chloroplast. The 10 DAE (days after emergence) chloroplast started to form grana structure. The typical grana structure was observed 17 DAE, and the grana was fully developed 28 DAE. The membrane proteins obtained from just after emerging leaf were separated into many minor bands indicating no CP-complex formation yet. LHC II was detected after 10 days. CP 47 and CP 43 were detected after 17 days. After 28 days, the PS I and PS II proteins were distinctly separated into CP 1, LHC II, CP 47, CP 43, CP 29, CP 27+24. Thus, the appearance of the light harvesting protein, LHC II, which was concentrated in grana stacks, was consis tent in time with the formation of grana stacks 17 DAE. Key words Chloroplast ultrastructure, grana, CP-complex, LHC II.

• IEMEK Journal of Embedded Systems and Applications
• /
• v.8 no.6
• /
• pp.295-301
• /
• 2013

In this paper, we propose a real-time centralized soft motion control system for high speed and precision robot control. The system engages EtherCAT as high speed industrial motion network to enable force based motion control in real-time and is composed of software-based master controller with PC and slave interface modules. Hard real-time control capacity is essential for high speed and precision robot control. To implement soft based real time control, The soft based master controller is designed using a real time kernel (RTX) and EtherCAT network, and servo processes are located in the master controller for centralized motion control. In the proposed system, slave interface modules just collect and transfer all sensor information of robot to the master controller via the EtherCAT network. It is proven by experimental results that the proposed soft motion control system has real time controllability enough to apply for various robot control systems.

• The Transactions of the Korean Institute of Electrical Engineers
• /
• v.32 no.6
• /
• pp.199-204
• /
• 1983

In this paper, we investigated that the Al-Amorphous Se-Al structure had a large photovoltage and a Dark EMF (DEMF). This DEMF phenomena did not show just after the fabrication of a sample. However, it was shown after a few days, and it was increased with time, and was saturated after 30 days. Just after the fabrication of a sample, by appling the positive voltage on a sample for 100mins, we observed almost the same effect as had shown in a aging experiment. As the results, we found that Al3+ ions has related to a DEMF by migrating into amorphous Se, and form a trap in amorphous Se. We have also observed the photocapacitance effect to identify this trap formation.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.17 no.32
• /
• pp.121-126
• /
• 1994

Setup Time Reduction is an important aspect of the Just-in-Time(JIT) and Zero Inventory(Zl) Concepts since it supports reductions in manufacturing lead times and inventories. It also enables small lot sizes and kanban systems implementation for material flow - achieving major improvements in production floor management. One concept fundamental to the pursuit of JIT production in Japan and other countries is adoption of a setup time reduction. This paper looks at the necessities of setup time reduction and the relations to machine utilization. By using an EOQ model for evaluate the effect of setup time reduction, we get the results that over 75 % reduction in setup time is obtain the desired results in the lot size reduction.

• Proceedings of the Korean Information Science Society Conference
• /
• 2010.11a
• /
• pp.141-142
• /
• 2010