• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
• /
• pp.193-193
• /
• 2002

The subacute toxicities and toxicokinetics of a new fluoroquinolone antibiotics, DW-224a, were evaluated after single (at the 1st day) and 4-week (at the 28th day) oral administration of the drug, in doses of 0 (to serve as a control), 10, 30 and 90 mg/kg/day, to male and female dogs (n = 3 for male and female dogs for each dose).(omitted)

• Bulletin of the Korean Chemical Society
• /
• 제13권4호
• /
• pp.419-425
• /
• 1992

Conducting polypyrrole doped with iron (Ⅱ,Ⅲ) hexacyanate Fe$(CN)_6^{z-}$ ions was studied for its physical and electrochemical properties. The polymer exhibited two pairs of waves in the cyclic voltammogram, one for the reversible oxidation/reduction of the incorporated iron hexacyanate ions and the other for the near-reversible oxidation/reduction of the polypyrrole moiety. The exchange of ions incorporated in the polymer and other ions present in solutions were examined by following the decrease of the reversible redox peaks of Fe$(CN)_6^{z-}$, and by EDX analysis. The spin density of this highly conducting polymer as probed by ESR spectroscopy was extremely low compared to polypyrrole doped with common anions.

• 한국정보처리학회:학술대회논문집
• /
• 한국정보처리학회 2012년도 추계학술발표대회
• /
• pp.702-704
• /
• 2012

최근 클라우드가 새로운 패러다임으로 등장하면서 클라우드 서비스가 급증하고 있으나 대부분 인프라 서비스 또는 소프트웨어 서비스로 플랫폼 서비스의 경우 상대적으로 서비스 제공 사례가 적다. 하지만 최근 플랫폼 서비스를 제공하는 사례가 증가하고 있으며 이는 새로운 플랫폼 종속성의 우려를 낳고 있다. 즉 플랫폼 서비스를 선택하여 어플리케이션 개발이 이루어지면 계속 같은 플랫폼 서비스를 사용해야만 하는 종속성이 생기는 것이다. 본 논문에서는 이러한 클라우드 플랫폼 서비스 종속성 문제를 해결하기 위해 개방형 클라우드 플랫폼 서비스의 필요성과 함께 표준프레임워크를 기반으로 개방형 클라우드 플랫폼 서비스를 구현할 수 있는 방안을 제시하고자 한다.

• Journal of Microbiology and Biotechnology
• /
• 제31권6호
• /
• pp.875-881
• /
• 2021

The mitochondrial targeting domain (MTD) of Noxa contributes to its mitochondrial localization and to apoptosis induction. As a peptide, MTD fused with octa-arginine (R8), a CPP, induces necrosis related to intracellular calcium influx and destruction of mitochondria and endoplasmic reticulum. We searched for homologs of MTD, and compared their cell killing capability when fused with R8. Three of the seven peptides triggered cell death with similar mechanisms. The comparative analysis of peptide sequences showed that four amino acid sites of MTD are critical in regulating necrosis, suggesting the potential to generate artificial, adjustable cytotoxic peptides, which could be effective medicines for many diseases. Thus, homologs functionality could hint to the functions of their belonging proteins.

• 한국임상수의학회지
• /
• 제35권6호
• /
• pp.299-301
• /
• 2018

A 7-year-old intact female Shih-Tzu with chylothorax was presented. Percutaneous popliteal computed tomographic lymphangiography was performed to evaluate the thoracic duct and seek any potential cause of chylothorax. Despite two attempts, visualization of the thoracic duct failed and perianal subcutaneous computed tomographic lymphangiography with injection of iodinated, nonionic water-soluble contrast medium (0.6 ml/kg) was performed. A single branch of intact thoracic duct and dilated and tortuous lymphatics were detected. It was diagnosed as idiopathic chylothorax. Perianal subcutaneous lymphangiography is considered a less-invasive, easy and reliable method to visualize lymphatics in patients with chylothorax.

• 지식경영연구
• /
• 제20권1호
• /
• pp.155-174
• /
• 2019

Variety of data have been opened or connected by several levels of government. In smart city initiatives, open data become the source of a new business model. This paper is to foster ways of public open data (POD) by analyzing the start-up company that utilizes POD. In order to fulfill it, this paper adapts the case study research. Findings say that POD has potential to validate and further enrich the platform business. But to find which types of public open data are most prevalent is insufficient. To do this, it is more needed that sophisticated and many cases should be examined. However, this paper shows that platform business by using POD could lead to reduce the cost and increase the benefits for both providers and customers. From the findings, this paper shows that public open data has an important role not only to boost new venture creations which are prevalent ways of smart city but also to foster different platforms enabling new value capture and creation according to development of internet of things based on ICT technology.

• 산업융합연구
• /
• 제14권1호
• /
• pp.39-45
• /
• 2016

This paper deals with the consideration of mathematical models with regards to growth of cluster and firms by reviewing the Metcalf and Breuner's articles. prior studies have been argued the phenomenon of local industrial clusters and districts. Several concepts have been adopted to support the success of and changes to these clusters and firm growth. Through the review of two papers, evolution of both cluster and firm growth may be achieved in terms of utilizations of the different local aspects and mechanisms. This paper supports the theoretical back bone with regards to the regional cluster policy implementing in Korea for the purpose of regional developments. In particular, a mathematical model that, on a more abstract level, captures the fundamental dynamic structure of all the observed mechanisms. On the basis of this model, the emergence and evolution of local clusters can be described. Also this model has given that the knowledge sharing between firms has an important role to firms and cluster' growth.

• Structural Engineering and Mechanics
• /
• 제77권3호
• /
• pp.395-406
• /
• 2021

Near-field underwater explosion (UNDEX) phenomena were investigated by experiments and numerical simulations. The UNDEX experiments were performed in a water tank using a ship-like model. One kilogram of TNT, one of the most widely used military high explosives, was used for the experiments. Numerical simulations were performed under the same conditions as in the experiments using the commercial software LS-DYNA. Underwater pressures, accelerations, velocities, and strains by shock waves were measured at multiple locations. Further, the bubble pulsation period and the whipping deformations of the ship-like model were explored. The experimental results are presented and examined through comparison with the results obtained from widely used empirical equations and numerical simulations.

• 한국멀티미디어학회논문지
• /
• 제24권2호
• /
• pp.328-335
• /
• 2021

In the era of 'Untact', virtual reality-based job training platforms are actively being used as part of non-face-to-face education for students with developmental disabilities. Because the people with developmental disabilities may lack sufficient cognitive abilities, it is difficult to conduct untact training seamlessly without the help of a third party. Therefore, it is necessary for training programs to identify the right timing to provide help so that the training can be continued. This research analyzed the visual attention of students with developmental disabilities in virtual reality-based job training program in order to determine the point of time when an intervention is required by the trainee. Results showed that students who completed the mission tended to have intense visual attention on a small number of objects for a certain period of time; the visual attention of the students who failed tended to shift erratically among multiple objects.

• Journal of Veterinary Science
• /
• 제23권3호
• /
• pp.42.1-42.6
• /
• 2022

A 1-year-old male Persian cat was presented for castration. Liver incarcerated in a peritoneopericardial diaphragmatic hernia (PPDH) was diagnosed through pre-anesthetic tests. Multiple homogeneous hyperechoic nodules in the hepatic parenchyma were identified using ultrasound. The nodules showed decreased attenuation compared with normal hepatic parenchyma, and the herniated hepatic parenchyma showed increased arterial and decreased portal enhancement on computed tomography. From the histopathology, we diagnosed hydropic degeneration with portal fibrosis and myelolipoma. This report presents diagnostic imaging features of hepatic myelolipoma incarcerated in a PPDH in a cat. When perfusion of the hepatic parenchyma is altered, surgical treatment should be considered.