Insecticide resistance is a serious is a serious threat to IPM, resulting in various adverse effects not to mention the loss of yield in agriculture. One approach to counter the problem is the disruption of resistance mechanisms. This can be achieved by (1) compounds which show a negative correlation with resistance at the site of action, (2) specific metabolic inhibitors which serve as synergists, or (3) a certain combination of two insecticides producing a joint action. This approach, however, requires certain precautions for the side effects may cause an increase in toxicity to mammals. Owing to the recent advances in theoretical studies on resistance management employing computer simulation and mathematical models, a few principles to reduce the risk of development of resistance have been clarified. They are helpful in designing operational strategies with regard to, for instance, insecticide doses to be applied, mode of application, and choice and nature of the insecticide(s) to be used. For restoration of insecticide susceptibility of a resistant population, reintroduction of susceptible individuals to the resistant population is feasible when certain conditions are met. Natural enemies which developed resistance to insecticides can be an important component of IPM as has been shown in the pest management in apple orchards. After all, the implementation of a successful resistance management program depends upon cooperation between different sigments of the agricutural community. Although resistance is a preadaptive phenomenon, in some cases spontaneous loss of resistance does occur without contamination by susceptible individuals. The instability of resistance in these insects implies the possible existence of a switch machanism controlling the expression of resistance gene(s). Elucidation of such a mechanism may eventually provide us with a new technical approach with which we can combat the problem of insecticide resistance.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
/
v.27
no.1
/
pp.1-8
/
2001
This study was designed to localize the distribution of basic fibroblast growth factor(bFGF) in the developing rat condylar region and to elucidate the associated function of bFGF in the condyle development. The condyles of temporomandibular joint of Sprague-Dawley rats (27g of weight) were used. The tissues were examined with electron microscope and immunohistochemical method. The results were as follows: 1. The developing condylar region are divided in to 5 zones apparently: proliferative, maturation, hypertrophic, calcifying, and ossification zones. 2. The cells in the proliferative zone are condensed and have under-developed cell organells in the cytoplasm. This zone shows a strong immunoreactivity of bFGF. 3. The cells in the maturation zone are typical chondroblasts showing well-developed cell organells and round nucleus. The cartilaginous matrix does not show the immunoreactivity of bFGF, while the chondroblasts show the immunoreactivity. 4. The cells in the hypertrophic zone show hypertrophic change having the degenerated cell organelles and small nucleus. There are no immunoreactivity of bFGF in this zone except the nucleus and endoplasmic region showing mild immunoreactivity. 5, The cells in the calcifying zone show hypertrophic change and cell organelles are disappeared. The cells are surrounded by the calcified cartilaginous matrix. There are no immunoreactivity of bFGF in this zone except the endoplasmic region showing mild immunoreactivity. 6. In the zone of bone formation, chondroblasts are disappeared. Newly differentiated osteoblasts secreting osteoid around the calcified cartilaginous matrix. The bone marrow shows the immunoreactivity of bFGF, while the bone matrix does not show the immunoreactivity of bFGF.
Park, Kyung-Sook;Choi, Eun-Hee;Ryoo, Eon-Na;Hwang, Yun-Young;Chung, Hae-Kyung;Ahn, Yang-Heui;Paik, Hoon-Jung;Lim, Nan-Young;Lee, Eun-Ok
Journal of muscle and joint health
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v.11
no.1
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pp.18-30
/
2004
Purpose: The purpose of this study was to identify the trend of research on the nursing research in the journal of rheumatology health and to suggest future perspective for nursing research. Method: In this study, we reviewed the contents of 131 researches published in this journal from its beginning year 1994 to year 2003. Result: In the 85.5% researches, type of the research subjects was patient. research that subject is patient' family was none. An analysis of the research design showed, non-experimental research was 67.2%, experimental research was 26.7%, qualitative research was 5.3%, triangulation research was only one. In the experimental design types of nursing intervention were movement intervention 38.4%, cognitive intervention 38.4%. and true experimental research was none. Among non-experimental researches, 93.2% was survey method, methodological research was two, concept analysis research was two, a-method was one. Conclusion: There has been a lack of qualitative research, true experimental research, research using vary nursing intervention. Further research need nursing intervention development that intervention can be use in actual nursing care area.
This study was designed to distinguish by the characteristic difference and the degree of symptoms such as fatigue, pain, coping to pain, and efficacy on pain, and to offer descriptive data for nursing intervention for improving coping ability to pain along each characteristics of disease in chronic arthritis and systemic lupus erythematosus. The subjects were 135 outpatients in the hospital for rheumatic disease in H-university, Seoul. The data were collected by structural questionnaire, from April 29 to June 29, 1999. The results were that the fatigue score was high in the OA patients while the RA patients and SLE patients experienced middle range of fatigue score, but which was not statistically different. Although the RA patients felt higher pain than other diseases, they have well coped with their pain than the others. In efficacy on pain the SLE patients had higher score than others but all of the disease showed lower score. No statistically significant difference among the three group was recorded in efficacy on pain. Therefore, pain management in the RA patients was primary nursing intervention because they felt severe pain and have well coped with pain while they had lower pain efficacy score than the others. It is also important that fatigue management and coping strategies on pain for the OA patients and SLE patients are specially supportive in the nursing intervention.
Kang, Young-Ah;Lim, Kyung-Choon;Kim, Joo Hyun;Jeoung, Jae Sim;Han, Ji Eun
Journal of muscle and joint health
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v.26
no.3
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pp.290-306
/
2019
Purpose: This study aimed to describe the experiences of health-care providers about advanced practice nurses (APNs) focusing on the perspectives of physicians and APNs in Korea. Methods: Qualitative data were collected with snowball sampling. Six physicians and 13 APNs participated in this study through in-depth interviews or a focus-group interview. Qualitative content analysis was employed. Results: Three themes and seven categories were emerged. Three themes were 1) challenging start and attempts to settle down on unfamiliar system, 2) being positioned as an APN at clinical settings, 3) long journey for social recognition and legal institutionalization of APNs' role. Seven categories were 1) challenges to new area, 2) introduction and conflict of APN system, 3) driving force for stepping toward becoming APNs, 4) dedication and commitment to role development, 5) efforts to prove APNs' competency, 6) approaches to guarantee legal APNs' activities, and 7) filling the gap in health-care service. Conclusion: The findings suggest that health-care providers who have collaborated with APNs are aware of the needs to operate APN system more stably through the legislation of APNs' scope of practices. Further research is needed to provide the evidences of APNs' practice outcomes such as health care quality, patient safety, reduction of medical expenses, etc.
Kim, Yoon-Kyung;Park, Kyung Hee;Lee, Jay Jung Jae;Kim, Jeong-Hee;Song, Hyo Jeong
Journal of muscle and joint health
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v.27
no.2
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pp.160-168
/
2020
Purpose: This study aimed to provide basic data for the development of an education program on diabetic foot prevention care for care helpers in long term care facilities. Additionally, it sought to determine care helpers' knowledge and practice regarding diabetic foot prevention care, and to identify the correlation between such knowledge and practice. Methods: This cross-sectional study employed a structured questionnaire. Participants consisted of 90 care helpers who were working in three long term care facilities in Jeju city. Data collection was conducted from September to November 2016. Results: The mean knowledge and practice scores were 8.77±1.28 (range 0~10) and 28.17±2.44 (range 10~30), respectively. Practice regarding diabetic foot prevention care was significantly different by care helpers' gender (t=-2.28, p=.024), period of career in the long term care facility (F=3.29, p=.025), and received education on diabetic foot prevention care (t=3.08, p=.005). A positive correlation was observed between knowledge and practice (r=.35, p<.001). Conclusion: To improve the practice of diabetic foot prevention care, specialized education programs that consider gender and period of career in the long term care facility as well as the improvement of the level of knowledge of care helpers on diabetic foot prevention care are needed.
Moon, Byung Young;Park, Kwang Bok;Hong, Young Jun;Lee, Sung Bum;Lee, Ki Yeol
Journal of Advanced Marine Engineering and Technology
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v.39
no.5
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pp.527-535
/
2015
As a new technical approach, a hydraulic and magnetic clamp device was attempted to realize a magnetic clamp crane system that uses 8 simultaneously actuating individual hydraulic cylinders. Through this approach, a Sr type of ferritic permanent magnet ($SrO{\cdot}6Fe_2O_3$), not the previously employed electro-magnet, was utilized for the purpose of lifting and transporting the heavy weighted and oversized curved steel plates used for manufacturing the ships. This study is aimed at manufacturing and developing the hydraulic magnetic clamp prototype, which is composed of three main parts - the base frame, cylinder joint, and magnet joint - in order to safely transport such curved steel plates. Furthermore, this research was pursued to conduct a performance evaluation as to the prototype manufacture and acquire the planned quantity value and the development purpose items. The most significant item for a performance evaluation was estimated for the magnetic adhesive force (G) and in this process, a ferritic permanent magnet (Sr type) with 3700~4000 G of residual induction (Br) and 2640/2770 Oe of coercive force (Hc) was utilized. In addition, other relevant items such as hoist tension (kN), transportation time (sec), and the applied load (Kgf) exerted on the hydraulic cylinders were also evaluated in order to acquire the optimum quantity value. As a result of the evaluation, the relevant device turned out to be suitable for safely transporting the curved steel plates.
PURPOSES: The objective of this study is to evaluate construction issues and design for transverse steel in continuously reinforced concrete pavement(CRCP). METHODS : The first continuously reinforced concrete pavement(CRCP) design procedure appeared in the 1972 edition of the "AASHTO Interim Guide for Design of Pavement Structures", which was published in 1981 with Chapter 3 "Guide for the Design of Rigid Pavement" revised. A theory that was accepted at that time for the analysis of steel stress in concrete pavement, called subgrade drag theory(SGDT), was utilized for the design of reinforcement of CRCP - tie bar design and transverse steel design - in the aforementioned AASHTO Interim Guide. However SGDT has severe limitations due to simple assumptions made in the development of the theory. As a result, any design procedures for reinforcement utilizing SGDT may have intrinsic flaws and limitations. In this paper, CRCP design procedure for transverse steel was introduced and the limitations of assumptions for SGDT were evaluated based on various field testing. RESULTS: Various field tests were conducted to evaluate whether the assumptions of SGDT are reasonable or not. Test results show that 1) temperature variations exist along the concrete slab depth, 2) very little stress in transverse steel, and 3) warping and curling in concrete slab from the field test results. As a result, it is clearly revealed out that the assumptions of SGDT are not valid, and transverse steel and tie bar designs should be based on more reasonable theories. CONCLUSIONS : Since longitudinal joint is provided at 4.1-m spacing in Korea, as long as joint saw-cut is made in accordance with specification requirements, the probability of full-depth longitudinal cracking is extremely small. Hence, for transverse steel, the design should be based on the premise that its function is to keep the longitudinal steel at the correct locations. If longitudinal steel can be placed at the correct locations within tolerance limits, transverse steel is no longer needed.
Aluminium nitride(AlN) is currently under investigation as potential candidate for replacing alumium oxide(Al$_{2}$$O_{3}$) as a substrate material for for electronic circuit packaging. Brazing of aluminium nitride(AlN) to Cu with Ag base active alloy containing Ti has been investigated in vacuum. Binary Ag$_{98}$$Ti_{2}$(AT) and ternary At-1wt.%Al(ATA), AT-1wt.%Ni(ATN), AT-1wt.% Mn(ATM) alloys showed good wettability to AlN and led to the development of strong bond between brate alloy and AlN ceramic. The reaction between AlN and the melted brazing alloys resulted in the formation of continuous TiN layers at the AlN side iterface. This reaction layer was found to increase by increase by increasing brazing time and temperature for all filler metals. The bond strength, measured by 4-point bend test, was increased with bonding temperature and showed maximum value and then decreased with temperature. It might be concluded that optimum thickness of the reaction layer was existed for maximum bond strength. The joint brazed at 900.deg.C for 1800sec using binary AT alloy fractured at the maximum load of 35kgf which is the highest value measured in this work. The failure of this joint was initiated at the interface between AlN and TiN layer and then proceeded alternately through the interior of the reaction layer and AlN ceramic itself.
Kim, Kyung;Kim, Jae-Jun;Heo, Min;Jeong, Gu-Young;Ko, Myoung-Hwan;Kwon, Tae-Kyu
Journal of Institute of Control, Robotics and Systems
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v.16
no.10
/
pp.948-956
/
2010
The purpose of this study was to test the effectiveness of a prototype KAFO (Knee-Ankle-Foot Orthosis) powered by two artificial pneumatic muscles during walking. We had previously built powered AFO (Ankle-Foot Orthosis) and KO (Knee Orthosis) and used it effectively in studies on assistance of plantaflexion and knee extension motion. Extending the previous study to a KAFO presented additional challenges related to the assistance of gait motion for rehabilitation training. Five healthy males were performed gait motion on treadmill wearing KAFO equipped with artificial pneumatic muscles to power ankle plantaflexion and knee extension. Subjects walked on treadmill at 1.5 km/h under four conditions without extensive practice: 1) without wearing KAFO, 2) wearing KAFO with artificial muscles turned off, 3) wearing KAFO powered only in plantaflexion under feedforward control, and 4) wearing KAFO powered both in plantaflexion and knee extension under feedforward control. We collected surface electromyography, foot pressure and kinematics of ankle and knee joint. The experimental result showed that a muscular strength of wearing KAFO powered plnatarfexion and knee extension under feedforward control was measured to be lower due to pneumatic assistance and foot pressure of wearing KAFO powered plnatarfexion and knee extension under feedforward control was measured to be greater due to power assistance. In the result of motion analysis, the ankle angle of powered KAFO in terminal stance phase was found a peak value toward plantaflexion and there were difference of maximum knee flexion range among condition 2, 3 and 4 in mid-swing phase. The current orthosis design provided plantaflexion torque of ankle jonit in terminal stance phase and knee extension torque of knee joint in mid-swing phase.
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