• IMMUNE NETWORK
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• v.22 no.2
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• pp.14.1-14.17
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• 2022

Osteoarthritis (OA) is a common degenerative joint disease characterized by breakdown of joint cartilage. Mitochondrial dysfunction of the chondrocyte is a risk factor for OA progression. We examined the therapeutic potential of mitochondrial transplantation for OA. Mitochondria were injected into the knee joint of monosodium iodoacetate-induced OA rats. Chondrocytes from OA rats or patients with OA were cultured to examine mitochondrial function in cellular pathophysiology. Pain, cartilage destruction, and bone loss were improved in mitochondrial transplanted-OA rats. The transcript levels of IL-1β, TNF-α, matrix metallopeptidase 13, and MCP-1 in cartilage were markedly decreased by mitochondrial transplantation. Mitochondrial function, as indicated by membrane potential and oxygen consumption rate, in chondrocytes from OA rats was improved by mitochondrial transplantation. Likewise, the mitochondrial function of chondrocytes from OA patients was improved by coculture with mitochondria. Furthermore, inflammatory cell death was significantly decreased by coculture with mitochondria. Mitochondrial transplantation ameliorated OA progression, which is caused by mitochondrial dysfunction. These results suggest the therapeutic potential of mitochondrial transplantation for OA.

• Journal of Mechanical Science and Technology
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• v.16 no.8
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• pp.1053-1063
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• 2002

This paper presents a robust nonlinear controller for a f degree of freedom (DOF) parallel manipulator in the task space coordinates. The proposed control strategy requires information on orientations and translations in the task space unlike the joint space or link space control scheme. Although a 6 DOF sensor may provide such information in a straightforward manner, its cost calls for a more economical alternative. A novel indirect method based on the readily available length information engages as a potential candidate to replace a 6 DOF sensor. The indirect approach generates the necessary information by solving the forward kinematics and subsequently applying alpha-beta-gamma tracker With the 6 DOF signals available, a robust nonlinear task space control (RNTC) scheme is proposed based on the Lyapunov redesign method, whose stability is rigorously proved. The performance of the proposed RNTC with the new estimation scheme is evaluated via experiments. First, the results of the estimator are compared with the rate-gyro signals, which indicates excellent agreement. Then, the RNTC with on-line estimated 6 DOF data is shown to achieve excellent control performance to sinusoidal inputs, which is superior to those of a commonly used proportional-plus-integral-plus-derivative controller with a feedforward friction compensation under joint space coordinates and the nonlinear controller under task space coordinates.

• Journal of the Korea Institute of Building Construction
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• v.1 no.2
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• pp.185-190
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• 2001

The purpose of this study is the development of practical Dry floor tile unit method that settle the defect of a wet method and designed for resin mat. With use of PE resin which is confirmed the basic property, it is developed that resin mat, joint-sealing compound with fixed form and space management to Dry floor tile unit method. The result of this study is below. 1) To acquire above the 4kgf/$\textrm{cm}^2$ - construction specification criterion, the bonding space that between resin mat and tile has to occupy the 50% of resin mat module space(10,000$\textrm{cm}^2$). 2) Criteria of bonding part plane is below. simpleness of metal form. productivity, uniform quality after injection molding cooling, easy cutting for remain space management, adhesive property, construction ability, transformation of a severed piece under pressure and so on. 3) To get the shape that could protect the interfacial breakdown, it is designed that resin mat and tile are unified after the bond input. 4) Adapted joint-sealing compound is the material of urethane kinds wedge form. Resin mat has the water passageway that could drain the water. 5) To manage the severed piece of tile, the resin mat is likely to divide the half and the quarter and the plastic drainage is developed in the severed piece.

• Proceedings of the KIEE Conference
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• 2004.07c
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• pp.1775-1777
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• 2004

Taihan Electric Wire Co. developed accessories(PJ, EB-G, EB-A, EB-O) for 345kV XLPE $1C{\times}600mm^2$ cable as a small size conductor cable, after installed 345kV XLPE $1C{\times}600mm^2$ cable, PJ and EB-G on Youngseo${\sim}$Youngdeungpo project KEPCO planed in 2003. All of 345kV XLPE $1C{\times}600mm^2$ cable Accessories are finished the type tests successfully. Straight joint as a Prefabricated Joint(PJ) had shorter the days of assembling than those of TMJ used on the 154kV XLPE Cable. Particularly, the use of clean booth to prevent the dusts and the penetration of water also had made the quality of jointing improved.

• Journal of muscle and joint health
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• v.20 no.2
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• pp.81-90
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• 2013

Purpose: The purpose of this study was to identify factors contributing to health-related quality of life in patients under rehabilitation after stroke. Methods: A descriptive correlational study design was used. Ninety-two stroke patients under rehabilitation from a university hospital were included. Data were collected on March and April, 2013 using structured questionnaires. Hierarchial multiple regression analysis was used to identify factors influencing health-related quality of life. Results: There were significant differences in health-related quality of life according to type of impairment. The health-related quality of life had significant correlations with age, functional dependency, and stress. Factors influencing health-related quality of life for stroke patients under rehabilitation were stress, functional dependency, type of impairment, and age, which explained about 34.5% of total variance. Conclusion: To promote health-related quality of life for stroke patients under rehabilitation, stress and functional dependency should be managed in this population, especially for older adults. Also these results can be utilized in the development of program for helping rehabilitation of stroke patients. The effect of depression and anxiety on health-related quality of life should also be addressed in future research.

• Journal of muscle and joint health
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• v.22 no.2
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• pp.130-137
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• 2015

Purpose: This study aims to establish a theoretical framework for the fall prevention behavior improvement program by verifying the associations between fracture risk, fall risk perception, and fall prevention behaviors in women with osteoporosis. Methods: A survey was conducted in 122 women who were diagnosed as osteoporosis by having T-score of the femur bone density below -2.5 standard deviation from the bone density examination performed in 2 orthopedic clinics located in B metropolitan city between July 2014 and September 2014. The risk of fracture, level of fall risk perception, and fall prevention behaviors were measured. Results: Fall risk perception had a complete mediating effect on the relationship between the fracture risk and fall prevention behaviors in women with osteoporosis. Conclusion: The perception of fall risk is important to enhance fall prevention behaviors in women with osteoporosis, and the development of various education programs to improve awareness of fall risk is needed.

• Journal of muscle and joint health
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• v.22 no.2
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• pp.57-66
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• 2015

Purpose: The purpose of this study was to evaluate the incidence of postoperative delirium in elderly patients with osteoarthritis surgery and identify risk factors for its development. Methods: This study enrolled 288 patients who underwent osteoarthritis surgery in a hospital between May and November 2014. Data were collected prospectively. The Nursing Delirium Screening Scale was used to detect delirium. Multivariable logistic regression analysis was used to identify independent risk factors for postoperative delirium. Patients were also followed for outcome. Results: Postoperative delirium developed in 42 patients (14.6%). Logistic regression analysis identified old age, low physical activity, antipsychotic agents, number of catheters, and intensive care unit admission as risk factors. Worse outcomes, including increased hospital mortality, reoperation, and discharge at care facilities, occurred in subjects who developed delirium. Conclusion: Osteoarthritis surgery in elderly patients was associated with a high incidence of postoperative delirium. The results of the this study regarding patient populations vulnerable to delirium should be taken into account so that such patients could be identified preoperatively or in the immediate postoperative period.

• Journal of muscle and joint health
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• v.20 no.3
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• pp.247-257
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• 2013

Purpose: The purpose of this descriptive study was to investigate the knowledge of radiation protection and the recognition and performance of radiation protection behaviors among perioperative nurses. This study was intended to yield basic data for the development of nursing interventions aimed at improving the nurses' radiation protection behaviors. Methods: One hundred and thirty-seven nurses working in the operating room participated in a survey from September 1 to 30, 2011. The data was analyzed using t-test, ANOVA, and Pearson's correlation with the SPSS/WIN 19.0 program. Results: The average score of radiation protection knowledge was $7.57{\pm}3.45$ out of 16. The average score for the recognition and performance of radiation protection behaviors was $4.32{\pm}0.23$. The knowledge of radiation protection was significantly correlated with the recognition and performance of radiation protection behaviors. Conclusion: Expanding the knowledge of radiation protection could lead to the increase of the recognition and performance of radiation protection behaviors. Therefore, promoting the performance of radiation protection behaviors by improving perioperative nurses' knowledge of radiation protection through reinforcing radiation-related education hereafter could be an important part of nursing.

• Journal of muscle and joint health
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• v.23 no.2
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• pp.125-137
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• 2016

Purpose: The purpose of this study was to identify the influences of hospital employees' daily life posture habits and work-related factors upon musculoskeletal subjective symptoms. Methods: This study was a descriptive survey study. Data were collected using structured a self-report questionnaire between April 1 and May 31, 2015. One hundred and ninety two employees were recruited in three hospitals. The collected data were analyzed using descriptive statistics, ${\chi}^2$ test, t-test, and binomial logistic regression. Results: The habit of leaning on one side and the habit of bending the back in an improper posture are key postures based on lifestyle affecting musculoskeletal subjective symptoms in neck, shoulders, arms, waist, and legs. Labours accompanying repeated arm movements for a long time are key work-related risk factors affecting musculoskeletal subjective symptoms in arms. Conclusion: The results of this study confirmed that, to prevent musculoskeletal diseases, it is necessary to identify and mediate personal factors like daily life posture habits as well as work-related risk factors. They may be utilized as basic materials for education of musculoskeletal health promotion and development of life guidance programs.

• Advances in robotics research
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• v.2 no.2
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• pp.113-127
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• 2018

Robotics and automation are rapidly growing in the industries replacing human labor. The idea of robots replacing humans is positively influencing the business thereby increasing its scope of research. This paper discusses the development of an experimental platform controlled by a robotic arm through Robot Operating System (ROS). ROS is an open source platform over an existing operating system providing various types of robots with advanced capabilities from an operating system to low-level control. We aim in this work to control a 7-DOF manipulator arm (Robai Cyton Gamma 300) equipped with an external vision camera system through ROS and demonstrate the task of balancing a ball on a plate-type end effector. In order to perform feedback control of the balancing task, the ball is designed to be tracked using a camera (Sony PlayStation Eye) through a tracking algorithm written in C++ using OpenCV libraries. The joint actuators of the robot are servo motors (Dynamixel) and these motors are directly controlled through a low-level control algorithm. To simplify the control, the system is modeled such that the plate has two-axis linearized motion. The developed system along with the proposed approaches could be used for more complicated tasks requiring more number of joint control as well as for a testbed for students to learn ROS with control theories in robotics.