• 대한수의학회지
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• 제32권3호
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• pp.281-293
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• 1992

Classification of the cycle of seminiferous epithelia into 12 stages by the morphological changes in acrosomal system and evaluation of the relative frequency of stages and the cell association were histologically performed in the mature Korean native Jin-do dogs. The results were summarized as follows; 1. The minimum number of type A spermatogonia averaged 1.01 at stages I, while maximum number averaged 2.47 at stages XII. Some type A spermatogonia divided at stage XII to produce the type intermediate(IN) spermatogonia at the following stage I. The type IN spermatogonia divided at stage IV to produce the type B spermatogonia at stage V. 2. The type B spermatogonia divided at stage VI to produce the preleptotene primary spermatocytes at stage VII. The secondary spermatocytes observed at stage XII. The secondary spermatocytes observed at stage XII divided to give rise to the round spermatids at the following stage I. The numbers of the first spermatocytes and spermatids were almost constant, respectively, through all the cycles of seminiferous epithelium. 3. The acrosomal vesicle was invaginated to occupy one third to half of spermatid nucleus at the cap phase, which was different from that of rodent and ruminant spermatid nuclei. 4. The relative frequencies of stages I to XII of seminiferous epithelia cycle were 10.34, 4.84, 5.03, 8.22, 10.86, 6.63, 6.42, 18.88, 10.17, 6.18, 7.62% and 4.81%, respectively.

• 생명과학회지
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• 제29권6호
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• pp.637-644
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• 2019

본 연구에서는 우리나라 토종견인 제주개의 보존 보호를 위해 그에 대한 유전적 특성을 파악하고자 개 7품종(제주개, 동경개, 독일 세퍼트, 진도개, 라브라도 레트리버, 풍산개, 삽살개)에 대해 총 139두와 microsatellite 마커 16종을 이용하여 대립유전자형을 분석하였다. 그 결과 16종의 marker에서 131개의 대립유전자 좌위를 확인하였고, 이 중 FH3381에서 18개의 가장 많은 대립유전자형이 확인되었으며 FH2834는 대립유전자형이 2개로 가장 적게 확인되었다. 또한, 마커별 기대되는 이형접합도의 전체적 평균치를 보았을 때 기대이형접합도와 관측이형접합도가 외래견보다 토종개가 높게 나타났고 PIC값은 0.000부터 0.862로 확인되었다. 제주개와 다른 품종 간의 계통수를 분석한 결과 삽살개와 94%로 가장 가까운 것으로 확인 되었다. 제주개와 다른 품종들 간의 유전적 거리를 확인한 결과 삽살개가 0.393으로 가장 가깝게 나타났고 토종개 중에서는 동경개와의 거리가 0.507로 가장 먼 것으로 나타났다. 개체별의 분포도를 살펴보면 제주개는 레트리버, 삽살개와 같은 그룹 내에 존재하였고 풍산개, 동경개, 진도개, 셰퍼트가 같은 그룹 내에 존재한 것을 알 수 있다. 따라서 본 연구 결과를 통해 확인된 유전적 특성 정보들은 제주개의 유전적 특성 연구에 이용할 수 있는 기초적 자료로 활용가치가 높은 것으로 사료된다.

• 한국임상수의학회지
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• 제33권3호
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• pp.176-178
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• 2016

Here we report a case of a 7-month-old Jindo puppy with a double intussusception. On survey radiography, a soft tissue opacity mass was identified in the mid-abdomen. Abdominal ultrasonography revealed a triple-circle sign. Double intussusception was diagnosed based on these findings. Exploratory laparotomy confirmed it to be a double intussusception in the small intestine. Small intestine involving the double intussusception was surgically resected followed by anastomosis. The dog had good prognosis without any complication. To the best of our knowledge, double intussusception is an extremely rare form of intestinal disease in dogs. It may cause blood supply to that section to be greatly reduced, thus causing ischemia and necrosis of the bowel tissue. Timely diagnosis with ultrasonographic findings and immediate surgical intervention are important to improve the prognosis of such cases.

• 한국임상수의학회지
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• 제18권3호
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• pp.237-242
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• 2001

The garlic has been eaten widely regardless of easten and westen countries to cure the various disease like cancer, tuberculosis, dentalgia, toxemia and leprosy from ancient times. Even now it is reported that they lower the level of triglycerides and cholesterol in blood and that they also affect on the cohesive power of the platelets. In addition, it is also known that it lowers the glucose level in blood. Especially, the sulfur containing amine acid and the derivatives of the garlic has the counteracting effect to heavy metals. Nowadays, the garlic is known for its efficiency for the various kinds of cancer, neoplasms, hypertension, arteriosclerosis and apoplexy. However, it is reported that the intake of the excessive amount of garlic causes hemolytic anemia recently. The hemolytic anemia is more severe especially in HK phenotype dogs which has Na-K-ATPase activity. Therefore, this study was performed to examine the effect on the blood of the HK phenotype Jindo dogs when administered the excessive amount of garlic. HK phenotype group showed the significant decrease on RBC, WBC, PCV, Hb, MCV, MCHC, GSH, Met-Hb but LK phenotype group didn's show the significant decrease. AST, ALT, BUN, creatinine, CPK, glucose, and total protein values were within normal ranges during the period.

• 한국임상수의학회지
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• 제17권2호
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• pp.321-326
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• 2000

전라남도 진도군 내에서 사육되는 진돗개에서 발생한 유산의 일부가 Brucell canis 에 의하여 유발된 것임을 확인하였다. 이 연구에서는 먼저 1997년 7월에서 1998년 6월 사이에 발생한 진돗개의 유산을 설문조사로 확인하였던 바 발생률이 18.5%에 달했다. 이어서 설문조사에 포함된 지역에서 사육되는 진돗개를 대상으로 신시한 혈청학적 조사에서는 25%가 양성을 보였으며, 수캐의 양성률은 암캐의 거의 두 배에 달했다. 다음으로 균 분리와 치료시험을 실시하기 위하여 유산 병력을 기치고 있으면서 혈청검사에서 양성을 나타낸 암캐 다섯 마리를 현지에서 구입하였다. 그 중 세 마리는 안락사 시킨 후 부검하여 자궁을 검사하고 균 분리를 시도한 바 세 미리 모두에서 B. canis가 분리되었다. 그러나 육안적 및 조직학적 변화 는 현저하지 않았다. 나머지 두 마리는 minocycline과 streptolmycin으로 치료하였는데, 치료를 끝낸 후 8주에 실시한 혈청검사에서 음성을 보였다. 이 연구의 결과는 개 부루셀라병이 진돗개를 사육하는 농가에 경제적 손실을 초래하고 있음을 나타내준다. 아울러 대부분의 진돗개가 방사되고 있으며, 그렇게 사육된 개들이 전국적으로 팔려나가고 있기 때문에 진돗개가 개 부루셀리병의 전파원으로 작용할 가능성을 지니고 있음을 나타내준다 천연기념물인 진돗개의 보 호와 농가의 소득 그리고 공중위생학적인 면에서 진품개의 부루셀라병에 관한 연구는 지속적으로 수행되어야 할 것으로 사료된다.

• 한국임상수의학회지
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• 제24권2호
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• pp.269-275
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• 2007

Two dogs referred to Veterinary Medical Center, Chungbuk National University diagnosed as multiple extrahepatic portosystemic shunt were reported. The first dog was a 20-month-old, 8 kg, male Cocker spaniel with history of peritoneal effusion, diarrhea, anorexia and stunted growth. The second dog was a 3-year-old, 13.4 kg, male Jindo with a history of severe depression. Hematologic examination of first dog revealed mild microcytosis and nonregenerative anemia. All of 2 cases, serum chemical values showed increase of serum ammonia, ALP, r-GTP and glucose. In survey radiography, microhepatia was apparent. In the color Doppler ultrasonographic examination, the first dog revealed a dilated tortuous vein communicating with caudal vena cava was observed near the left kidney and the second dog revealed numerous shunting vessels ventral to L5 and L6. Transcolonic portal scintigraphy of the first dog confirmed the presence of portosystemic shunt. In intraoperative jejunoportography, the first dog showed single congenital extrahepatic portosystemic shunt and multiple acquired extrahepatic portosystemic shunts. The second dog showed multiple acquired extrahepatic portosystemic shunts. In these dogs, the presence of congenital and acquried portosystemic shunts and histopathologic findings were considered to represent a combination of multiple extrahepatic portosystemic shunts and noncirrhotic portal hypertension or portal vein hypoplasia.

• 한국임상수의학회지
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• 제24권1호
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• pp.46-50
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• 2007

A 7-year-old female, Jindo dog was referred to the Veterinary Teaching Hospital with mild dyspnea and anorexia due to a gunshot trauma. The dog was wounded in the thoracic region 3 days ago. Plain radiographs showed the left 8th rib fracture, interstitial pattern in the left caudal lung field and pleural effusion. Abdominal radiographs showed the lead bullet. Computed tomographs(CT) showed the size of pulmonary contusion, laceration, lung parenchymal injuries, hemothorax and perforation of abdominal wall. The therapeutic plan was based on abnormalities seen on CT scans but not clearly seen in survey radiographs. Thoracic CT significantly provides even more informations compared with the corresponding radiographs in thoracic gunshot trauma. Although thoracic survey radiographs are useful as a screening tool, CT is highly sensitive in detecting thoracic injuries after thoracic trauma and is superior to routine thoracic survey radiographs in visualizing lung contusion, pneumothorax and hemothorax. Therefore, we recommend CT in the initial diagnostic work-up of patients with thoracic injuries and with suspected chest trauma because early and exact diagnosis of all thoracic injuries along with sufficient therapeutic consequences may reduce complications.

• 대한수의학회지
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• 제39권4호
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• pp.724-729
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• 1999

Amino acids, Na, K and glutathione (GSH) in red blood cells (RBCs) and hematological indices were examined in Korean dogs. A total of seven dogs possessing RBCs with high K and high glutathione (GSH)(HK/HG) were found in 42 Korean dogs : three from Cheju dog, two from Jindo dog and two from Korean mongrel. The RBCs in Korean HK/HG dog contained abnormally high aspartate (Asp), Glu and glutamine (Gln) the same as in HK/HG RBCs from Japanese Shiba dog. Two dogs possessing RBCs with HK and low GSH (HK/LG) were found in Cheju dog, and they accumulated Asp and Gln. Thus, not only the existence of HK dog was confirmed in Korean dogs, but HK/LG dog was also found. The Asp concentration in RBCs from seven of 33 LK dogs was more than $1000{\mu}mol/lc$, the same as in variant LK RBCs with defective Glu/Asp transport (LK/GAT), while it was less than $800{\mu}mol/lc$ in normal LK RBCs. Thus, there were variant dogs having RBCs with abnormally high amino acids accumulation among HK and LK Korean dogs.

• 한국임상수의학회지
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• 제22권4호
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• pp.435-438
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• 2005

Two dogs (case 1:2-year-old intact male German Shepherd-mixed dog and case 2: 4-year-old intact female Jindo miked) with perineal hernia were referred to the Chonbuk Animal Medical Center, Chonbuk National University. In the both cases, there were unilateral perineal swelling involving the right side of the anus. In addition, in case 2, swelling was also present ventral to the anus. Rectal palpation of pelvic diaphragm revealed weakness of the muscles. Both cases were surgically treated using muscle transposition technique for hemiorrhaphy. In case 1, transposition of the superficial gluteal and internal obturator muscles and in case 2, transposition oi semitendinosus muscle was performed for hemiorrhaphy and reconstruction of the pelvic diaphragm. Both dogs became recovered after the surgical correction and no complications were observed during 10-month (casel) and 9-month(case2). Muscle transposition can be a useful technique for the treatment of perineal hernia in the dog.

• 한국임상수의학회지
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• 제17권2호
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• pp.495-498
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• 2000

Leiomyosarcoma is defined as a malignant smooth muscle tumor or a tumor that arises from smooth muscle and it is found as firm. white and lobulated mass. Canine uterine Ieiomyosa- rcomas are rarely associated with clinical signs. We surveyed(one case which was treated at veter- inary medical leaching hospital of Seoul National University. Through this report we studied the meshed fur diagnosis of uterine leiomyosarcoma by symptom, hematological method and ultrahonog- raphy. To determine uterine leiomysarcoma is difficult due to similarity of clinical signs to pyometra. Especially symptoms could not be noticed even by dogs owners until dogs have an elevation of the number of white blood cells. We conclude ultrasonographic observation and experimental laparotomy are of great value to diagnose the uterine liomyosarcoma.