• Molecules and Cells
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• v.25 no.2
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• pp.301-304
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• 2008

Microsatellites, short tandem repeats, are useful markers for genetic analysis because of their high frequency of occurrence over the genome, high information content due to variable repeat lengths, and ease of typing. To establish a panel of microsatellite markers useful for genetic studies of the Korean population, the allele frequencies and heterozygosities of 207 microsatellite markers in 119 unrelated Korean, Indian and Pakistani individuals were compared. The average heterozygosity of the Korean population was 0.71, similar to that of the Indian and Pakistani populations. More than 80% of the markers showed heterozygosity of over 0.6 and were valuable as genetic markers for genome-wide screening for disease susceptibility loci in these populations. To identify the allelic distributions of the multilocus genetic data from these microsatellite markers, the population structures were assessed by clustering. These markers supported, with the most probability, three clustering groups corresponding to the three geographical populations. When we assumed only two hypothetical clusters (K), the Korean population was separate from the others, suggesting a relatively deep divergence of the Korean population. The present 207 microsatellite markers appear to reflect the historical and geographical origins of the different populations as well as displaying a similar degree of variation to that seen in previously published genetic data. Thus, these markers will be useful as a reference for human genetic studies on Asians.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.1
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• pp.11-16
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• 2016

Lithography techniques are generally used to manufacture nano-patterns on silicon, however, it is difficult to make a V-shaped pattern using these techniques. Although silicon is a brittle material, it can be treated as a ductile material if mechanically machined at extremely low force scale. The manufacturing technique of nano-patterns on single crystal silicon using a mechanical method was developed in this study. First, the linear pattern was machined on the silicon with increasing thrust force. Then, the correlation between measured cutting force and machined pattern was analyzed. Based on the analysis, the critical thrust force was quantitatively determined, and then the silicon was machined at a force lower than the critical thrust force. The machined pattern was observed using SEM and AFM to check for the occurrence of brittle fractures. Finally, the sharp V-shaped nano-pattern was manufactured on the single crystal silicon.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.13 no.2
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• pp.64-72
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• 2014

In the past, prism patterns have been linear triangular shapeswith a $90^{\circ}$ angle; however, new micro prism patterns having acute angles or obtuse angles have recently been the subject of demandin the display, lighting and photovoltaic industries. Micro-cutting experiments for micro-prism patterns having $60^{\circ}$, $90^{\circ}$, and $120^{\circ}$ angles on an electroplated Ni mold were performed and it was found in this study that the specific cutting resistance increased with a decrease in the tool angles (prism pattern angles). The cause of this variation had been thought to be the increase of the ploughing force due to tip rounding and the friction force due to the edge effect. However, the depth of the cut was large enough that it was possible to neglect these effects. Therefore, this study introduced the concept of representative stress of indentation. The measured stress was varied according to the indentation depth eventhoughthetestedspecimenswereidentical ; the varied stress was termed the representative stress. According to indentation theory, the strain that the Ni mold experienced increased with a decrease in the tool angle. Based on the stress-strain relationship, higher strain means higher stress and higher specific cutting resistance. Therefore, the specific cutting resistance was higher at smaller tool angles that had higher strain and stress.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.4C
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• pp.355-362
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• 2009

A new intra field deinterlacing algorithm with edge map in the image block is introduced. Conventional deinterlacing methods usually employ edge-based line average algorithm within pixel-by-pixel approach. However, it is sensitive to variation of intensity. To reduce this shortcoming, we proposed edge direction vector computed by edge map, and also its interpolation technique. We first introduce an edge direction vector, which is computed by Sobel mask, so that finer resolution of the edge direction can be acquired. The proposed edge direction vector oriented deinterlacer operates by identifying small pixel variations in five orientations, while weighted averaging to estimate missing pixel. According to the edge direction of the direction vector, we calculate weights on each edge direction. These weight values multiplied by the candidate deinterlaced pixels in order to successively build approximations of the deinterlaced sequence.

• Design & Manufacturing
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• v.13 no.4
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• pp.40-44
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• 2019

The light diffusion component spreads the light from one point evenly over a large area. Various types of light diffusion parts such as films and lenses are applied in the high-tech industries such as LCD display devices, lighting devices, and solar energy generation. Among these, a diffuser sheet (Diffuser Sheet) has a function to uniformly distribute the light, and various studies have been conducted to improve its function. The shape of the conventional light diffusion pattern is mainly made of a dot or hemispherical shape. In this study, a rectangular cone-shaped structure having a light diffusion function and an advantage of controlling the angle of refraction of light was fabricated by using a solenoid indentation process. The change in shape of the indentation structure was analyzed.

• Journal of Animal Environmental Science
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• v.19 no.2
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• pp.177-182
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• 2013

We studied the possibility to produce solid fuel using cattle manure and to apply TAO (Thermophilic Aerobic Oxidation) process of solid-liquid separation fraction. The physiochemical compositions of cattle manure solid fuel chip were analyzed as water 0.12%, low calorific value 3,510 kcal/kg, ashes 11.9%, chlorine 0.82%, sulfur dust 0.5%, mercury non-detection, cadmium 1.0 mg/kg, lead 2 mg/kg, arsenic non-detection. In treating cattle manure with TAO reactor the internal temperature of the reactor was increasing higher and $50^{\circ}C$ and over was maintained after 20 hours on. The physiochemical compositions of liquids increased from pH 7.3 to pH 9.18 and EC decreased from 4.6 to 3.48 mS/cm in treating process of cattle manure with TAO reactor. COD and SCOD decreased from 16,800 to 10,400 mg/L, from 4,600 to 2,040 mg/L respectively, which showed about 38% and 56% of remove efficiency respectively.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.10a
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• pp.586-586
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• 2007

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.27 no.9
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• pp.463-467
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• 2015

The air-bubble sheet has been widely used to wrap fragile products for long-distance transportation. The further usage of the air-bubble sheet as a thermal-insulation material for the reduction of the thermal conductivities of window systems has occurred because of its low price, in addition to its thermal-conductivity properties. In this study, the thermal performances of a variety of commercial air-bubble sheets according to various applications were evaluated. The experiments were performed with single-glazed and double-glazed windows and three types of air-bubble sheets of different air volumes. U-values are used and were calculated for the determination of the thermal performances that are based on the KS F 2278. The maximum decrease of the U-value was measured as 1.092 when a sheet was attached onto the frame of single-glazed window. The square-like air-bubble sheet that contains the largest air volume shows the highest thermal-resistance value. Double layers of the air-bubble sheets show better performances than those of the single layers on both sides of the windows.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.1C
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• pp.19-33
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• 2008

A method that is adaptively selecting among previous fast motion estimation algorithms and a newly proposed fast motion estimation algorithm(UCDS) is presented in this paper. The algorithm named AUDC and a newly proposed fast motion estimation algorithms are based on the Diamond Search(DS) algorithm and Three Step Search(TSS). Although many previous fast motion estimation algorithms have lots of advantages, those have lots of disadvantages. So we thought better adaptive selection of fast motion estimation algorithms than only using one fast motion estimation algorithm. Therefore, we propose AUDC that is using length of the MV, Search Point, SAD of the neighboring block and adaptively selecting among Cross Three Step Search(CTSS), Diamond Search(DS) and Ungraded Cross Diamond Search(UCDS). Experimental results show that the AUDC is much more robust, provides a faster searching speed, and smaller distortions than other popular fast block-matching at algorithms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1449-1459
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• 2009

Coptidis rhizoma (huanglian) is an herb that is widely used in traditional Chinese medicine that has recently been shown to possess anticancer activity. However, the molecular mechanism underlying the anticancer effects of this herb is poorly understood. In this study, we investigated the anticancer activity of a combination of CR extract and arsenic trioxide, as well as the apoptotic pathway associated with its mechanism of action in human lung cancer H157 cells. Combined treatment of H157 cells with CR extract and arsenic trioxide resulted in significant apoptotic death. In addition, combined treatment with CR extract and arsenic trioxide acted in concert to induce a loss of mitochondrial membrane potential (${\Delta}{\Psi}$), the release of cytochrome c from mitochondria, and an increase in the expression of pro-apoptotic p53 and Bax protein, which resulted in activation of caspases and apoptosis. CR extract combined with arsenic trioxide also increased the lipid peroxidation, mRNA expression of DR4 and DR5 and caspase-8 activity. These data indicate that combined treatment with CR extract and arsenic trioxide enhanced apoptotic cell death in H157 cells through diverse pathways, including mitochondrial dysfunction and death receptors, particularly DR4 and DR5. Thus, this treatment may be an effective from of chemotherapy.