• KSBB Journal
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• v.25 no.4
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• pp.330-336
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• 2010

In this study, a new compound, 1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-1-methoxy-3-phenylpropane; (Jeju-Erythrane) was isolated and identified from the bark of Lindera erythrocarpa Makino. Also, we investigated the effects of Jeju-Erythrane on alpha melanocyte-stimulating hormone (MSH)-induced melanogenesis in mouse B16F10 melanoma cells. The new compound dose dependently inhibited the tyrosinase activity and melanin synthesis in B16F10 cells. The new compound showed inhibitory effect on the Tyrosinase and TRP-1 gene transcription but not on the TRP-2 gene. These results suggest that the new compound of L. erythrocarpa could be used as a functional biomaterial in developing skin whitening agent.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2005.07a
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• pp.33-33
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• 2005

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.252-254
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• 2022

The purpose of this study is to show the works of Jeju artists and ways to contribute to the Jeju tourism industry, with the research background in that it has recently continued to accept the works of Jeju contemporary artists and draws active works. As a measure to achieve this research purpose, the Deep Dream Generator software was judged to be an effective method for promoting this study. As a specific research process, we will use the Deep Dream Generator to synthesize each of the works of Jeju artists and works of famous foreign artists provided by Deep Dream Generators with their own photos of Jeju Oreum and display the results, and attempt to reinterpret Jeju Oreum using artificial intelligence. In addition, it is expected to revitalize Jeju's art works and tourism by seeking ways to use the results in Jeju tourism products.

• Toxicological Research
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• v.34 no.1
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• pp.83-83
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• 2018

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.39-39
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• 2022

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.40-40
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• 2022

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.42-42
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• 2022

• Genes and Genomics
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• v.40 no.11
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• pp.1249-1258
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• 2018

The Jeju horse is an indigenous Korean horse breed that is currently registered with the Food and Agriculture Organization of the United Nations. However, there is severe lack of genomic studies on Jeju horse. This study was conducted to investigate genetic characteristics of horses including Jeju horse, Thoroughbred and Jeju crossbred (Jeju${\times}$Thoroughbred) populations. We compared the genomes of three horse populations using the Equine SNP70 Beadchip array. Short-range Linkage disequilibrium was the highest in Thoroughbred, whereas $r^2$ values were lowest in Jeju horse. Expected heterozygosity was the highest in Jeju crossbred (0.351), followed by the Thoroughbred (0.337) and Jeju horse (0.311). The level of inbreeding was slightly higher in Thoroughbred (-0.009) than in Jeju crossbred (-0.035) and Jeju horse (-0.038). $F_{ST}$ value was the highest between Jeju horse and Thoroughbred (0.113), whereas Jeju crossbred and Thoroughbred showed the lowest value (0.031). The genetic relationship was further assessed by principal component analysis, suggesting that Jeju crossbred is more genetically similar to Thoroughbred than Jeju horse population. Additionally, we detected potential selection signatures, for example, in loci located on LCORL/NCAPG and PROP1 genes that are known to influence body. Genome-wide analyses of the three horse populations showed that all the breeds had somewhat a low level of inbreeding within each population. In the population structure analysis, we found that Jeju crossbred was genetically closer to Thoroughbred than Jeju horse. Furthermore, we identified several signatures of selection which might be associated with traits of interest. To our current knowledge, this study is the first genomic research, analyzing genetic relationships of Jeju horse, Thoroughbred and Jeju crossbred.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.3
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• pp.1099-1104
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• 2012

The purpose of this study is to explore the authenticity of Jeju architecture, to give attention to contemporary architecture that we inhabit, and to escape from existing architectural discourse of Jeju architecture. This study seeks the ontological thinking of Jeju architecture on the basis of the judgement of critique and ontology of architecture. The ontological thinking of Jeju architecture can be studied in the aspect of disinterested of authenticity and ontological question of authenticity. As a result of this study, two aspects in the ontological thinking of Jeju architecture are revealed. One aspect of the authenticity of Jeju architecture is laying in the disinterested area. Another aspect is that authenticity of Jeju architecture is revealed through the ontological question of Jeju architecture. These aspects mean the authenticity of Jeju architecture as thinking which represents ontological layer of Jeju architecture.

• Fashion & Textile Research Journal
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• v.15 no.3
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• pp.406-413
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• 2013

The objective of this research is to find out status and consciousness about shrouds according to changes of Jeju's rural funeral ritual while reviewing Jeju's traditional shrouds. Consciousness of customs regarding tradition is much stronger in Jeju Island. Since it was said that shrouds and changes of funeral ritual have very systematic correlation according to the result of precedent researches, changes of funeral rituals of Jeju's rural area were examined. At the same time, consciousness about traditional shrouds of Jeju people was also studied. As the result of examination through literary investigation, visits to rural homes, visits to production places of Jeju's shrouds and interviews with grandmothers designated as human cultural assets of traditional Jeju shrouds, etc, it was found out that Jeju's rural funeral rituals had been rapidly changed since 2000. Traditional Jeju shrouds are also disappearing. In particular, old women of Jeju have considered preparation of their own and their husbands' shrouds in advance as a virtue. However, as it gradually became more difficult to produce and prepare traditional shrouds at homes and as the space of funeral was changed from their own houses to hospitals and/or commercial funeral homes, it was found out that a ratio of people's using general shrouds sold in market was increased and it is believed that this kind of trend will be accelerated more and more in the future.