• Knowledge Management Research
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• v.21 no.3
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• pp.105-121
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• 2020

With regard to the development of new drugs, what is most important for a Korean Biotech, where no global sales network has been established, is decision-making related to out-licensing of new drugs. The probability of success for each clinical phase is different, and the licensing amount and its royalty vary depending on which clinical phase the licensing contract is made. Due to the nature of such a licensing contract and Biotech's weak financial status, it is a very important decision-making issue for a Biotech to determine when to license out to a Big Pharma. This study defined a model called 'optimal timing for out-licensing of new drugs' and the results were derived from the decision tree analysis. As a case study, we applied to a Biotech in Korea, which is conducting FDA global clinical trials for a first-in-class new drug. Assuming that the market size and expected market penetration rate of the target disease are known, it has been shown that out-licensing after phase 1 or phase 2 of clinical trials is a best alternative that maximizes Biotech's profits. This study can provide a conceptual framework for the use of management science methodologies in pharmaceutical fields, thus laying the foundation for knowledge and research on out-licensing of new drugs.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.10a
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• pp.331-339
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• 2008

Nowadays with advancement in technology and aging society, the number of disabled citizens is increasing. The disabled citizens always need a caretaker for daily life routines especially for mobility. In future, the need is considered to increase more. To reduce the burden from the disabled, various devices for healthcare are introduced using computer technology. The power wheelchair is an important and convenient mobility device. The demand of power wheelchair is increasing for assistance in mobility. In this paper we proposed a robotic wheelchair for mobility aid to reduce the burden from the disabled. The main issue in an autonomous wheelchair is the automatic detection and avoidance of obstacles and going to the pre-designated place. The proposed algorithm detects the obstacles and avoids them to drive the wheelchair to the desired place safely. By this way, the disabled will not always have to worry about paying deep attention to the surroundings and his path. User has a handheld bio-sensor monitoring system for get user's bio-signal. If user detects unusual signal, alarm send to protector.

• Journal of Cadastre & Land InformatiX
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• v.47 no.2
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• pp.175-184
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• 2017

Recently, PM10 is becoming a main issue in Korea because it causes a variety of diseases, such as respiratory and ophthalmologic diseases. This research studied to spatial information application cases for evaluating the feasibility of the location for PM10 observation stations utilizing Geogrphic Information System(GIS) spatial analysis. The spatial Information application cases for optimal location assessment were investigated to properly manage PM10 observation stations which are closely related with public spatial data and health care. There are 31 PM10 observation stations in Seoul city and the observed PM10 data at these stations were utilized to understand the overall assessment of PM10 stations to properly manage using interpolation methods. The estimated PM10 using Inverse Distance Weighted(IDW) and Kriging techniques and the map of PM10 concentrations of monitoring stations in Seoul city were compared with public spatial data such as precipitation, floating population, elementary school location. On the basis of yearly, seasonal and daily PM10 concentrations were used to evaluate the feasibility analysis and the location of current PM10 monitoring stations. The estimated PM10 concentrations were compared with floating population and calculated 2015 PM10 distribution data using zonal statistical methods. The national spatial data could be used to analyze the PM10 pollution distribution and additional determination of PM10 monitoring sites. It is further suggested that the spatial evaluation of national spatial data can be used to determine new location of PM10 monitoring stations.

• Journal of KIISE
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• v.44 no.7
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• pp.658-667
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• 2017

The demand for large-scale storage systems has continued to grow due to the emergence of multimedia, social-network, and big-data services. In order to improve the response time and reduce the load of such large-scale storage systems, DRAM-based in-memory cache systems are becoming popular. However, the high cost of DRAM severely restricts their capacity. While the method of compressing cache entries has been proposed to deal with the capacity limitation issue, compression and decompression, which are technically difficult to parallelize, induce significant processing overhead and in turn retard the response time. A selective compression scheme is proposed in this paper for in-memory file system caches that rapidly estimates the compression ratio of incoming cache entries with their Shannon entropies and compresses cache entries with low compression ratio. In addition, a description is provided of the design and implementation of an in-kernel in-memory file system cache with the proposed selective compression scheme. The evaluation showed that the proposed scheme reduced the execution time of benchmarks by approximately 18% in comparison to the conventional non-compressing in-memory cache scheme. It also provided a cache hit ratio similar to the all-compressing counterpart and reduced 7.5% of the execution time by reducing the compression overhead. In addition, it was shown that the selective compression scheme can reduce the CPU time used for compression by 28% compared to the case of the all-compressing scheme.

• Journal of the Society of Disaster Information
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• v.11 no.1
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• pp.73-88
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• 2015

Due to the cases of recent global warming and unusual weather etc., large-scale natural disasters such as typhoons, floods, snow damage occur frequently across the continents such as Southeast Asia and North America, South America etc. and risks of earthquakes and tsunami are also increasing gradually in Korea which has been regarded as a safe zone and disaster types are also being diversified such as typhoons, floods, heat waves, heavy snow and damage scale is also enlarged. In addition, due to geographical characteristics or lack of infrastructure, disasters tended to occur intensively around a specific region or city in the past but disasters occur throughout the country in recent years so preparation for disaster prevention has emerged as an urgent challenge issue. Therefore, considering that the plan of obtaining the effective feedback function of disaster Information is very important in the proactive and software aspects for disaster reduction, this paper analyzed this three aspects of contents, procedural and contextual aspects and proposed the plan. First, in the content aspect, building disaster prevention information communication Infrastructure, building urban and regional disaster prevention system, obtaining concurrency and sharing of information and second, in the procedural aspect, active utilization of ICT(Information and Communication Technology) of the prevention stage, disaster prevention information collection and analysis reinforcement of the preparation stage, improvement of decision-making structure and field command system of the response stage, recovery system related information promotion of the recovery stage were proposed as alternatives and finally, in the contextual aspect, if disaster prevention information is effectively managed through maintenance of disaster prevention information related systems, obtaining domainality by disaster prevention work, improvement of the ability to judge the situation, obtaining comprehensive and feedback function etc, it is considered to significantly contribute to reducing natural disasters.

• Journal of the Korean Regional Science Association
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• v.15 no.2
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• pp.155-187
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• 1999

The East Asian Region has experienced remarkable economic growth and transformation of interurban networking over the past three decades, and urban competiti veness for a networking hub in this region has become a critical issue confronting cities. Competitiveness of the Seoul capital region for a networking hub in Northeast Asia is outstripped by other competing cities in East Asia, notwithstanding its geo-politically and geo-economically advantageous location in this region. In this paper, we aim to appraise the Seoul capital region's competitiveness in terms of logistics distribution, financial function and logistics distribution, financial function and agglomeration of transnational corporations (especially of RHOs and other managerial functions), and to advance the networking strategies of the region for a Northeast Asia hyb. As a result of analysis, we suggest that the Seoul capital region be developed as a Northeast Asian center for regional headquarters or leading global corporations and financial services for being a strategic nodal point in Northeast Asia in the 21st century. A recent survey shows that where to locate an RHQ is influenced by various factors, such as potential market and manufacturing site in the city's hinterland, quality of life, such things as culture, health, safety, education, a well-educated, English-speaking population, reliable air transport, state-of-the-art communications, and an active policy to offer foreign companies generous incentives. The Seoul capital region, which is located at a strategic nodal point advantageous as a springboard for its Northeast Asian hinterland, cannot meet the other conditions mentioned above. To overcome these drawbacks in attracting transnational capital and to create competitiveness as a strategic hub of RHQs in Northeast Asia, it is urgent to initiate a structural reform of the Korean economy, politics, and overall society, to minimize the regulation of FDI, and to provide various incentives for foreign investment. Moreover, we propose the construction of an 'International Business Town' in the Seoul capital region, as a medium to intermediate these strategies and to shape them in a spatial scale. The projected 'International Business Town(IBT)' will be a 'free city' open to international business in which liberal economic activities are guaranteed by special legislation and administration, infrastructures needed for international and improved accessibility to the airport are furnished, and the preference of foreign high-income investors for cultural and living environment are satisfactorily met. IBT is conspicuously differentiated from a raft of other cities' incentives in that it combines deregulation and incentive programs to attract the investment of transnational capital, with a spatial program of offering an urban environment preferred by the high-income investors for cultural and living environment are satisfactorily met. IBT is conspicuously differentiated from a raft of other cities' incentives in that it combines deregulation and incentive programs to attract the investment of transnational capita, with a spatial program of offering an urban environment preferred by the high-income and managerial class. Furthermore, it can be an excellent way of overcoming the xenophobia that has spread among the Korean population by concentrating foreign businesses and their lifestyles in a specific foreign businesses and their lifestyles in a specific zone. In conclusion, 'International Business Town', in line with other legislative and administrative incentive programs, will function as a driving force to make the Seoul capital regional more competitive as a regional business hub in Northeast Asia.

• Journal of Korean Society of Transportation
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• v.31 no.3
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• pp.55-64
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• 2013

Conventionally, greenhouse gas (GHG) emissions in the transport sector have been estimated using the fuel consumption (i.e. Tier 1 method). However, the GHG emissions on road networks may not be practically estimated using the Tier 1 method because it is not practical to monitor fuel consumption on a road segment. Further, air pollutant emissions on a road may not be estimated efficiently by the Tier 1 method either due to the diverse characteristics of vehicles, such as travel speed, vehicle type, model year, fuel type, etc. Given these conditions, the goal of this study is to propose a Tier 3 level methodology to calculate $CO_2$ and $NO_X$ emissions on inter-regional roads using the information from ITS infrastructure. The methodology may avoid the under-estimation issue caused by the concavity of emission factor curves because the ITS speed or volume information is aggregated by a short time interval. The proposed methodology was applied to 4 road segments as a case study. The results show that the management of heavy vehicles' speed is important to control the $CO_2$ and $NO_X$ emissions on road networks.

• Journal of KIISE:Information Networking
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• v.32 no.3
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• pp.415-426
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• 2005

Wireless internet, which becomes a hot social issue, has limitations due to the following characteristics, as different from wired internet. It has low bandwidth, frequent disconnection, low computing power, and small screen in user terminal. Also, it has technical issues to Improve in terms of user mobility, network protocol, security, and etc. Wireless internet server should be scalable to handle a large scale traffic due to rapidly growing users. In this paper, wireless internet proxy server clusters are used for the wireless Internet because their caching, distillation, and clustering functions are helpful to overcome the above limitations and needs. TranSend was proposed as a clustering based wireless internet proxy server but it has disadvantages; 1) its scalability is difficult to achieve because there is no systematic way to do it and 2) its structure is complex because of the inefficient communication structure among modules. In our former research, we proposed the All-in-one structure which can be scalable in a systematic way but it also has disadvantages; 1) data sharing among cache servers is not allowed and 2) its communication structure among modules is complex. In this paper, we proposed its improved scheme which has an efficient communication structure among modules and allows data to be shared among cache servers. We performed experiments using 16 PCs and experimental results show 54.86$\%$ and 4.70$\%$ performance improvement of the proposed system compared to TranSend and All-in-one system respectively Due to data sharing amount cache servers, the proposed scheme has an advantage of keeping a fixed size of the total cache memory regardless of cache server numbers. On the contrary, in All-in-one, the total cache memory size increases proportional to the number of cache servers since each cache server should keep all cache data, respectively.

• Journal of the Korea Society of Computer and Information
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• v.25 no.8
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• pp.159-172
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• 2020

Social networking services (SNS) are developing significantly with the Internet and smartphones. It's a friendly social media, but if you think deeply about it, you'll find that it has a variety of faces. It is a communication tool between users, a medium for delivering information, an infrastructure for providing applications, and a community where people with common interests gather. In recent years, business tools, shopping and payment methods are also being swallowed. The influence of the spread of SNS on the real world is also expanding, and the work being dealt with from a sociological perspective is also increasing. Also, if you pay attention to the technical aspects of SNS, it is composed of various technical elements, such as infrastructure that handles large-scale access, user interface that supports comfortable use, and big data analysis to understand people's behavior more deeply. However, I usually use it as usual. However, if you look through SNS, you can see that the situation is surprisingly profound and multifaceted. This study began by looking at the history and current status of SNS and attempted to find its status through comparison with other media. From the point of view of relationship with society, it can be a risk and legal issue when using SNS, such as crimes using bad social media or social media. It is also necessary to comment on the activities on SNS or the guidelines established by the operators. Therefore, various legal issues on SNS will be discussed. Also, as an example of using SNS, I will introduce an example of using SNS in disaster response. From a more technical point of view, you will receive commentary on SNS's network-based technology and SNS's information use, and these articles will help you understand and use SNS safely and help you further utilize or develop SNS.

• Korean journal of communication and information
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• v.56
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• pp.48-70
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• 2011

Although many researchers propose that market-driven journalism is incurred by the worsening of financial situation as a result of intensifying competition in mass media industry, few studies investigated this claim with actual news data. This study analyzed the headline news of eight major newspapers and two terrestrial TV companies to find the weakening of 'orientating-journalism' function of Korean news media. The results revealed that the duplication rate of news items among ten news companies were decreasing, and the range of news subjects were broadened into diverse topics during last ten years. Therefore it seemed that the tendency of monopolization of a certain events or issues was weakening in news reporting. The financial situation of news companies is an important factor in explaining the change of news reporting. The companies with more worse financial situation have higher duplication rate of news topics along as the more amount of soft news items, leading to the gradual deterioration of their own voices in reporting. The rate of 'independent issue report' was also less than seven precent, thus their reporting is evaluated as having many limitations. In sum, the major newspapers and network broadcasting companies are still exerting strong influences in agenda-setting, but they(mostly newspapers) are suffering from the financial problems, resulting the deterioration of performing orientation journalism function. This study concluded with remarks about the role of major news media in current changing situation.