• Journal of Biomedical Engineering Research
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• v.24 no.3
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• pp.175-181
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• 2003

Studies of muscle fatigue have mostly been checked under isometric exercise. However EMG signals from isotonic exercise generate uncontrollable noise, so there were difficulties in gathering reliable median frequency and muscle fatigue index if frequency analysis was equally applied in isometric exercise. This study tried to compare the differences of muscle fatigue determinant variables in terms of median frequency searching methods of EMG signal, which was estimated in isotonic exercise. To accomplish this, we determined median frequency by using different FFT intervals and overlapping ration of consecutive FFT sections under the same EMG signal, and then searched for a linear regression line, and compared initial median frequency, slope, and muscle fatigue index which were variables under the linear regression line. In result of comparison, initial median frequency was more elevated as FFT exercise interval became larger. The slope of the linear regression line showed distinguishable decreasing tendency as FFT intervals were larger and overlapping sections were smaller. Significant tendency of muscle fatigue index in FFT interval was shown by high muscle fatigue index in specific FFT intervals.

• YAKHAK HOEJI
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• v.57 no.4
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• pp.282-288
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• 2013

Zinc oxide nanoparticles (ZnONPs) are widely used in a variety of products and cosmetic products including paper, paints, plastics and sunscreen. However, information on the safety of ZnONPs are not enough and many publications suggest possible toxic effects on environmental and human health. Furthermore, physico-chemical characteristics of nanoparticles makes it hard to test toxicity using the test guidelines of chemicals adopted by regulatory bodies. In this study, stability of ZnONPs was investigated using different types of isotonic solution, which is important in the toxicity study of intravenous route. Precipitation, aggregation, size, zeta potential and morphology of ZnONPs were evaluated with different times and concentrations. Precipitation of ZnONPs were observed in ionic isotonic solution including phosphate-buffered saline, Kreb's-Ringer solution, physiological salt solution and cell culture media of DMEM (Dulbecco's Modified Eagle's Medium) with 10% fetal bovine serum. On the other hand, they were stable without precipitation in non-ionic isotonic solution such as 5% glucose and 2% glycerol, respectively, which are biocompatible for intravenous injection. The average size of ZnONPs in 5% glucose and 2% glycerol was stably maintained, which is less than 30 nm and very similar as that in water dispersion of ZnONPs, provided by the manufacturer. The stability was maintained during the experimental period of 5 days and diluted state up to 15,000 ppm. These data suggest that 5% glucose and 2% glycerol solution can be used for the vehicles of ZnONPs in the toxicity study of intravenous injection route.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.411-418
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• 2021

The purpose of this study was to find out the effects of isomatric and isotonic exercise on the muscle function and cytokine which will prevent recurrence of breast cancer patients. A subjects were thirteen breast cancer patients and they were randomly assigned either isometric exercise group(n=10), isotonic exercises group(n=10) or a daily base care control group(n=10). Resistance exercise group did a exercise program with 60~70%RM for 60min, 3days per week during 8week. There were significantly difference between groups which were showing a increasing flexion, abduction, external rotation, IL-6 and IL-10 in isotonic exercise.

• Journal of Biomedical Engineering Research
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• v.44 no.4
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• pp.284-292
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• 2023

This study attempted to observe muscle activity and muscle fatigue among isotonic exercise of Biceps Brachii and Deltoidus Medius, which correspond to upper limb muscles, using metronome. For the experiment, 13 adult men participated to evaluate biosignals (ECG, EMG). For quantitative evaluation, 1RM and MVIC test were carried out and a constant pace isotonic excise session was conducted. Five sets of exercise were performed, and each set proceeded to the failure point while the speed condition (30bpm) was assigned. As a result of the experiment, muscle activity in both muscles was significantly reduced in fifth set compared to first set. Muscle fatigue has been confirmed to occur at a significant level within the set, but there was only a significant difference in both muscles in the first and second sets between sets. This is similar to the results of previous studies that gives the same rest time(2min), but further research is needed to see if the conditions for the number of repetitions are affected. Based on the recent increase of interest in muscle strength exercise, this study was conducted to observe the results by varying the conditions of common exercise.

• Journal of Biosystems Engineering
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• v.36 no.4
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• pp.285-289
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• 2011

Muscle fatigue is characterized as a progressive increase in discomfort arising from the active muscle at moderate load levels are maintained. The median frequency is the most commonly used as a parameter to describe muscle fatigue. However, the estimate of the median frequency is difficult to indicate muscle fatigue because of its high standard deviation and instability. This paper investigates the power changes of the appropriate low frequency band as a fatigue parameter in EMG during isotonic exercise. To select the appropriate band, linear regression lines are employed to calculate the slopes and the coefficient of determination. Three females and seven males volunteered to participate in surface EMG recordings placed on the biceps brachii and each recording experiment continued until their exhaustion. The results of experiment shows that the power changes of the selected low frequency band (15~45 Hz) have linear slopes and high determinant coefficients. Therefore, this fatiguing parameter using the power changes of the low frequency band is valid to measure the state of muscular fatigue.

• PNF and Movement
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• v.5 no.2
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• pp.55-62
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• 2007

Purpose : The purpose of this study was to examine the effects of Rhythmic Stabilization(RS) and Combination of Isotonic(CI) of Proprioceptive Neuromuscular Facilitation on balance in patients with hemiplegia. Methods : Ten patients with hemiplegia were trained with RS and CI for six weeks. Two Standard Scale(TSS), Functional Reach Test(FRT), Time Up and Go test(TUG) and Berg Balance Scale(BBS) were used to prove their improvement of balance. Results : Body weight bearing decreased on less affected side and increased on more affected side. Distance of forward reaching for FRT increased. Time for TUG decreased. BBS score increased. They all showed significant difference. Conclusion : This study suggests that balance training with RS and CI of Proprioceptive Neuromuscular Facilitation improved balance in patients with hemiplegia.

• PNF and Movement
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• v.2 no.1
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• pp.25-33
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• 2004

Purpose : The purpose of this article is to summarize the characteristics of isotonic combination. Method : Some studies of the motor unit activation patterns during isometric, concentric, and eccentric actions, neural strategies in the control of muscle force, and concentric versus combined concentric-eccentric training were reviewed. Results & Conclusions : Eccentric torque may be relatively higher than concentric torque for two potential reasons: 1) stretch responses in the antagonist are not elicited to restrain the motion as can occur concentrically and 2) stretch responses in the agonist may augment eccentric torque production. Concentric-eccentric training has a greater influence on functional capacity than that of concentric training. Both maximal force and average force throughout the motion were significantly higher when the dynamic action was started with preactivation as compared to the mode without preactivation. The peak torques observed during the concentric phase of the eccentric-concentric muscle actions were higher than those noted in the pure concentric contraction.

• Journal of the Korean Statistical Society
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• v.21 no.2
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• pp.201-207
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• 1992

The algorithm for obtaining the isotonic regression in simple tree order, the most basic and simplest model next to the simple order, is considered. We propose to call it "Pool-the-Maximum-Violators" algorithm (PMVA) in conjunction with the "Pool-Adjacent-Violators" algorithm (PAVA) in the simple order. The dual problem of obtaining the isotonic regression in simple tree order is our main concern. An intuitively appealing relation between the primal and the dual problems is demonstrated. The interesting difference is that in simple order the required number of pooling is at least the number of initial violating pairs and any path leads to the solution, whereas in the simple tree order it is at most the number of initial violators and there is only one advisable path although there may be some others leading to the same solution.o the same solution.

• The Korean Journal of Applied Statistics
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• v.9 no.1
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• pp.153-164
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• 1996

We discussed estimation of parameters using Gibbs sampler under order restriction on the parameters. Two well-knwon probability models, ordered exponential family and binomial distribution, are considered. We derived full conditional distributions(FCD) and also used one-for-one sampling algorithm to sample from the FCD's under order restrictions. Finally through two real data sets we compared three kinds of estimators; isotonic regression estimator, isotonic Bayesian estimator and the estimator using Gibbs sampler.

• Physical Therapy Korea
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• v.10 no.1
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• pp.109-128
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• 2003

This study tested whether repeated measurement of median frequency (MDF)-related variables could express the muscle power changes during a 12-week DeLome strengthening program, by using consecutive overlapping FFT (Fast Fourier transformation) and integrated EMG (IEMG) from surface EMG data for isometric and isotonic exercise. To evaluate the effect of training, the following were recorded every 3 weeks for the elbow flexors and knee extensors of 5 healthy male volunteers: MVC, lRM, limb circumference, and surface EMG during isometric MVC or isotonic contraction at 10RM load. From the EMG data, IEMG and variables from a regression analysis between MDF and time were obtained. MVC, lRM, IEMG, and initial MDF increased linearly over the training period. The fatigue index and slope of the regression line increased temporarily until the 6th week and decreased thereafter. From these results, there appeared to be enhanced neural recruitment of fast twitch fibers in the first 6 weeks and continued enhancement in the recruitment and hypertrophy of fast twitch fibers, which led to increased fatigue resistance, over the last 6 weeks. Accordingly, the MDF and IEMG analysis technique could demonstrate the effect of the program detected significant changes in both isometric and isotonic contractions. EMG analysis methods can be used to estimate the electrophysiological and histological changes in skeletal muscles during a strengthening program.