• Title/Summary/Keyword: Iso-immunization

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A Case of Hemolytic Disease in a Newborn Due to Anti-Jkb (Anti-Kidd(Jkb) 항체 부적합증에 의한 신생아 용혈성 질환 1례)

  • Park, Dong-Kyun;Kim, Young-Min;Bae, Chong-Woo;Choi, Yong-Mook;Lee, Woo-In
    • Clinical and Experimental Pediatrics
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    • v.46 no.7
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    • pp.718-721
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    • 2003
  • The isoimmune hemolytic disease of newborn due to the incompatibility of minor blood groups is characterized by progressive neonatal hyperbilirubinemia and anemia caused by the IgG antibody transmitted from the mother to the fetus. Recently we had a case of hemolytic disease in a newborn due to $anti-Jk^b$. There were no ABO and Rh(D) incompatibilities between mother and baby. The infant's direct and indirect antiglobulin tests were strongly positive. From the mother and baby, an irregular antibody was found and identified as $anti-Jk^b$. Generally, hemolytic disease of the newborn resulting from $anti-Jk^b$ incompatibility has a benign clinical course and a good prognosis. This patient completely recovered without exchange transfusion. We report this case with a brief review of relevant literature.