• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6121-6125
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• 2014

Background: Prostate-specific antigen (PSA) is a potential biomarker for early detection of prostate cancer (PCa) but its level is known to be affected by many background factors and roles of ubiquitous toxicants have not been determined. Endocrine disrupting chemicals (EDCs) are ubiquitous reproductive toxicants used in consumer products, which promote tumor formation in some reproductive model systems by binding to AhR, but human data on its expression in prostate cancer as well as its association with PSA levels are not clear. This study aimed to evaluate the expression levels of AhR and its association with serological levels of PSA and to detect possible effects of background factors and EDC exposure history on PSA levels in PCa cases. Materials and Methods: A cross-sectional study was conducted on the tissue levels of AhR and serum levels of PSA in 53 PCa cases from 2008-2011 and associations between each and background and lifestyle related factors were determined. Results: Although the AhR was overexpressed in PCa and correlated with the age of patients, it did not correlate with PSA levels.Of nutritional factors, increased intake of polysaturated fats and fish in the routine regimen of PCa cases increased the PSA levels significantly. Conclusions: AhR overexpression in PCa pontws to roles of EDCs in PCa but without any direct association with PSA levels. However, PSA levels are affected by exposure to possible toxicants in foods whichneed to be assessed as possible risk factors of PCa in future studies.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4815-4818
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• 2013

Background: Atrophic epithelium of cervix sampled from postmenopausal women may mimic high-grade cervical intraepithelial neoplasia in Papanicolaou-stained (Pap) smears. Ki-67 (MIB-1) protein presents on proliferating cells, and percentage of cells with positive nuclei provides a reliable tool for rapid evaluation of the growth fraction. The aim of this study was to determine the diagnostic value of protein Ki67 staining in atypical pap smears of postmenopausal women. Methods: In a case-control setting, pap smears of 75 women with an atypical pap smear (case group) and 75 with normal pap smears (controls) were obtained before and after estrogen treatment. Afterward, samples were exposed to the monoclonal antibody Ki-67 (MIB-1) and the immunohistochemically demonstrated Ki-67+ cells were compared. Results: Mean ages of cases and controls were $60.4{\pm}4.5$ and $59.9{\pm}4.3$ years respectively (P=0.50). There was one (2.7%) positive Ki-67 specimen in the case group, without any positive Ki-67 specimen in the control group (P=0.50). Conclusions: Measurement of proliferative activity index in Pap smears restrained with MIB1 is a simple, reliable, and cost-effective method for excluding negatives. This would imply that it might allow a substantial reduction of diagnostic estrogen courses and subsequent Pap smears in postmenopausal women with atypical findings.

• Acta Via Serica
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• 제4권2호
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• pp.29-59
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• 2019

As 'a total social fact,' drinks and drinking may serve as a lens through which we can view a distant society. Although not frequently discussed, drinking vessels serve the same function for accessing a past world hidden or forgotten behind written records. The present article is an art history attempt to seek a cultural link between liquor vessels used in medieval Korea and the political and social change of the period. The Goryeo period (918-1392) saw an unprecedented abundance of drinking vessels in various forms and decorations. Goryeo artisans and craftsmen produced ewers, pitchers, flasks, bottles, and others in addition to the pre-existing shapes of vessels mainly consisting of jars and bowls. I argue that this sudden burst of creativity during the Goryeo period was closely related to Goryeo's constant and diverse contacts with foreign powers. Their zone of international connections was not confined to the Chinese world, as we have commonly presumed. Even before the Mongol intervention, Goryeo was in contact with regions beyond East Asia through the northern nomadic states. Khitan Liao was recorded as having worked as a kind of international intermediary to link the Chinese and Islamic worlds. This medieval global culture became a norm in Goryeo society when it became an important part of the Mongol Empire. These nomadic powers brought global trends to Goryeo, and foreign drinks were among them; kumis, araq, and grape wines are just three cases of them discussed in this article. The change of alcoholic drinks led to, or was accompanied by, a new range of drinking vessels. Three types of ewers, familiar to East Asian consumers but foreign in their origin, are discussed in the main text to highlight such social change. Three more cases of drinking cups are also presented. The article shows that medieval Korean society was far more open to international art and culture than our usual understanding, and in their drinking vessels, Goryeo culture embraced global trends reaching China, the Islamic world and Europe.

• Structural Engineering and Mechanics
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• 제77권1호
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• pp.115-135
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• 2021

This paper focuses on examining the effects of span arrangements on displacement responses of plan-symmetric RC frame buildings designed using the direct displacement-based design (DDBD) method by employing non-linear analyses and the skew seismic attack. In order to show the desired performance of DDBD design approach, the force-based design approach is also used to examine the seismic performance of the selected structures. To realize this objective, 8-story buildings with different plans are selected. In addition, the dynamic behavior of the structures is evaluated by selecting 3, 7, and 12-story buildings. In order to perform non-linear analyses, OpenSees software is used for modeling buildings. Results of an experimental model are used to validate the analytical model implemented in OpenSees. The results of non-linear static and non-linear dynamic analyses indicate that changing span arrangements does not affect estimating the responses of structures designed using the DDBD approach, and the results are more or less the same. Next, in order to apply the earthquake in non-principle directions, DDBD structures, designed for one-way performance, are designed again for two-way performance. Time history analyses are performed under a set of artificial acceleration pairs, applied to structures at different angles. It is found that the mean maximum responses of earthquakes at all angles have very good agreement with the design-acceptable limits, while the response of buildings along the height direction has a relatively acceptable and uniform distribution. Meanwhile, changes in the span arrangements did not have a significant effect on displacement responses.

• Acta Via Serica
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• 제7권1호
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• pp.53-82
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• 2022

The Hebrew word for silk, meshi, is mentioned in the Bible only once and there is a possibility that the item to which it referred was made of local wild silk. Although Jewish historical sources from the Roman and Byzantine periods mention silk many times, only a few silk textiles have been discovered at a sited dated to the Byzantine period (4^th-7^th centuries CE). The word "silk" occurs in the New Testament, although only once. A turning point in the history of the Negev (Southern Israel) occurred around 400 CE when it underwent a period of prosperity related to the advent of Christianity and pilgrimage, which enabled the purchase of imported silk textiles. The Early Islamic period (7-8th centuries CE) yielded four (out of 310) silk textiles from Nahal 'Omer on the Spice Routes joining Petra, in the Edom Mountains of modern Jordan, and the mercantile outlets on the Mediterranean Sea, notably Gaza and El Arish. The most important silk textile assemblage in the Southern Levant was found near Jericho at Qarantal Cave 38 and dates to the medieval period (9th-13th centuries CE). Linen textiles decorated with silk tapestry originating in Egypt date back to the 10-11th centuries CE. Mulham textiles - silk warp with hidden cotton wefts - were discovered in the medieval fortress on Jazirat Fara'un (Coral Island) in the Red Sea, 14 kilometers south of Elat and today located in Egypt. Mulham is mentioned in literary sources of the ninth century in Iraq and Iran, whence it spread through the Islamic world. The article will present aspects of the origin, transmission, and exchange of these textiles.

• Earthquakes and Structures
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• 제21권5호
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• pp.515-530
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• 2021

In a tall reinforced concrete (RC) core wall system subjected to strong ground motions, inelastic behavior near the base as well as mid-height of the wall is possible. Generally, the formation of plastic hinge in a core wall system may lead to extensive damage and significant repairing cost. A new configuration of core structures consisting of buckling restrained braced frames (BRBFs) and RC walls is an interesting idea in tall building seismic design. This concept can be used in the plan configuration of tall core wall systems. In this study, tall buildings with different configurations of combined core systems were designed and analyzed. Nonlinear time history analysis at severe earthquake level was performed and the results were compared for different configurations. The results demonstrate that using enough BRBFs can reduce the large curvature ductility demand at the base and mid-height of RC core wall systems and also can reduce the maximum inter-story drift ratio. For a better investigation of the structural behavior, the probabilistic approach can lead to in-depth insight. Therefore, incremental dynamic analysis (IDA) curves were calculated to assess the performance. Fragility curves at different limit states were then extracted and compared. Mean IDA curves demonstrate better behavior for a combined system, compared with conventional RC core wall systems. Collapse margin ratio for a RC core wall only system and RC core with enough BRBFs were almost 1.05 and 1.92 respectively. Therefore, it appears that using one RC core wall combined with enough BRBF core is an effective idea to achieve more confidence against tall building collapse and the results demonstrated the potential of the proposed system.

• 국제지역연구
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• 제17권4호
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• pp.155-179
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• 2013

본 연구의 목적은 남북 수단 분쟁의 역사와 과정을 고찰하여 남북 수단 분쟁을 이해하는데 있다. 이를 위해 분쟁원인과 해결에 대한 이론과 실제적 접근을 통해 분쟁원인과 해법의 일반론적인 검토와 더불어 남북 수단의 특별한 상황을 이해하고자 하였다. 이후 남북수단 분쟁의 역사적 배경 및 원인을 19세기 이전의 남북수단, 이집트의 수단 정복과 남북의 이질화, 영국의 식민지배와 남북 갈등 심화, 영국의 식민지배와 남북 갈등 심화, 수단의 독립에 따른 남북 수단 갈등, 종교와 자원을 둘러싼 남북의 갈등 등으로 구분해서 살펴보았다. 다음 장에서는 남북 수단 분쟁의 경과를 제1, 2차 내전으로 나누어 분석하였다. 남북 수단 분쟁은 이집트 영국의 식민지배 기간 중 남부와 북부의 분리통치 정책으로 인해 이질화가 심화되었고, 게다가 인종 종교 등 고질적 요소와 석유 이권을 둘러싼 갈등 등이 원인이었다. 2005년 합의된 포괄적 평화협정이 이행되어 남수단이 국민투표를 통해 분리 독립했다. 수단은 내전이 합의와 협정을 통해 해결된 아프리카 분쟁의 대표적 사례로 기록되고 있다. 이는 당시 전문가들이 수단 중앙정부가 2011년 분리 독립을 승인하지 않을 것이라는 전망을 내놓았던 것을 볼 때도 매우 이례적인 일로 받아들여지고 있다. 이제 수단은 남수단이 분리 독립하면서 새로운 전기를 맞이하고 있다. 그러나 아직까지 국경지역 일부와 유전이 개발되고 있는 몇몇 곳에서는 갈등과 충돌이 계속되고 있다. 특히 아비에이 지역을 둘러싸고 수단과 남수단은 합의점을 찾지 못하고 있다. 남북 수단분쟁은 아프리카 연합의 중재로 잠정 해결되었지만 근본적인 문제는 논란이 되고 있어 추가적인 합의가 필요한 시점이다. 양측과 국제사회의 합리적인 해법이 요구되고 있다.

• 한국도서관정보학회지
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• 제53권4호
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• pp.1-23
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• 2022

기록은 인간의 삶과 지식 세계에 대한 수상인 동시에 지문이다. 기록의 대명사로 간주되는 책은 인류 역사를 추적하는 통로이자 그것을 음미하는 창이다. 그리고 책의 가장 원시적인 형태는 고대 그리스·로마의 고전이고, 압권은 필사본이다. 그것은 파피루스 두루마리, 양피지, 종이 등에 기록한 원본과 그것을 번역·중역한 사본을 총칭한다. 장구한 지식문화사를 반추하면 서양 필사본은 자연적 재해뿐만 아니라 인위적 문화반달리즘과 비블리오코스트로 인하여 시공간을 유동하는 강물처럼 이합집산을 계속해 왔다. 이에 본 연구는 고대 그리스에서 중세 르네상스 시대까지 서양 필사본의 유량과 도서관 보존을 추적하였다. 그 결과, 왕조와 제국, 군주와 재상, 장군과 정복자, 귀족과 부유층, 성직자와 학자를 불문하고 고전 필사본을 수집하고 번역하는데 혈안이었다. 고대 그리스·로마의 석학들이 파피루스와 양피지에 지식과 지혜를 기록하지 않았으면, 중세 비잔티움 제국·이슬람 제국이 고전을 수집·번역하고 재생산하지 않았으면, 책 사냥꾼들이 고전을 추적하지 않았으면, 르네상스 인문주의자들이 지적 엑소더스를 통해 고전을 복원·재해석하지 않았으면, 그리고 역사도서관이 사력을 다해 고전과 번역본을 수집·보존하지 않았으면, 현대인은 고전 지식을 접할 수 없었을 것이다. 그럼에도 불구하고 고전 필사본의 추적은 역사적 유동, 지리적 유랑, 언어적 변용으로 인해 많은 난제와 모순이 중첩되어 있는 아포리아다. 새로운 필사본이 발견·해석되면 수정과 보완이 불가피하므로 후속연구를 통한 고전 필사본의 유랑과 귀환에 대한 추적은 계속되어야 한다.

• Earthquakes and Structures
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• 제18권5호
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• pp.649-665
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• 2020

One of the most important issues in structural systems is evaluation of the margin of safety in low and mid-rise buildings against the progressive collapse mechanism due to the earthquake loads. In this paper, modeling of collapse propagation in structural elements of RC frame buildings is evaluated by tracing down the collapse points in beam and column structural elements, one after another, under earthquake loads and the influence of column removal is investigated on how the collapse expansion in beam and column structural members. For this reason, progressive collapse phenomenon is studied in 3-story and 5-story intermediate moment resisting frame buildings due to the corner and edge column removal in presence of the earthquake loads. In this way, distribution and propagation of the collapse in progressive collapse mechanism is studied, from the first element of the structure to the collapse of a large part of the building with investigating and comparing the results of nonlinear time history analyses (NLTHA) in presence of two-component accelograms proposed by FEMA_P695. Evaluation of the results, including the statistical survey of the number and sequence of the collapsed points in process of the collapse distribution in structural system, show that the progressive collapse distribution are special and similar in low-rise and mid-rise RC buildings due to the simultaneous effects of the column removal and the earthquake loads and various patterns of the progressive collapse distribution are proposed and presented to predict the collapse propagation in structural elements of similar buildings. So, the results of collapse distribution patterns and comparing the values of collapse can be utilized to provide practical methods in codes and guidelines to enhance the structural resistance against the progressive collapse mechanism and eventually, the value of damage can be controlled and minimized in similar buildings.

• 패션비즈니스
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• 제15권3호
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• pp.112-124
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• 2011

Textile and clothing in Ancient Egypt have carried long history and tradition. Especially, Egyptian textile culture, created mostly by the Copt, has the originality of weaving technology and the artistic beauty of the weaving motifs, making the textiles comparable to modern textiles. The purpose of this study is to research on the characteristics of Coptic textile designs of ancient Egypt and the tunic, a basic garment made of Coptic textiles, and offer materials for the development of the textiles and designs with artistic values which can be shared in the modern era, not just for the research of the relics of the past. Therefore, this study will follow the historical background of Coptic textiles and the process of the development, and look into the distinct features under the categories of material, colors and motifs. In addition, the tunic and its weaving technology will be explained and this will help understand the originality of Coptic textiles. The scope of this study is limited to the period of the 3rd to 12th centuries when the Egyptian weaving technologies advanced dramatically and many of the ancient Egyptian textiles discovered from the grave goods dates back, the research methode of the tunic as well as books published at home and abroad, research paper and photograph works. The textiles had developed along the Egyptian history which was influenced by different cultures such as Greek, Roman, pagan, Christian, and later, Islamic. For the textiles, they used a variety of pictorial motifs including Greek goddesses, pastoral scenes related to the Nile River and animals, human figures, geometrical figures and Christian icons. They are symbolic, natural, and mythological characters, and this explains that the world views and religions of the weavers influenced the development of specific motifs. Coptic textiles was used to make a tunic, a simple straight-sided gown without sleeves worn by men and women and was woven in a combination of linen plain weave and woolen tapestry weave for a tunic. Not only the excellence of the weaving technologies and the beauty of the colors used in the textiles, but also the diversity of the textures through weaving, embroidery, and knotting are detected in Coptic textiles.