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Methodologic Aspect of LINAC-based Stereotactic Radiosurgery (선형가속기 기반 뇌정위 방사선 수술기법)

  • Choi, Tae Jin
    • Progress in Medical Physics
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    • v.23 no.3
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    • pp.127-137
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    • 2012
  • A conversing beam is firstly designed for radiosurgery by a neurosugern Lars Leksell in 1949 with orthogonal x-rays tube moving through horizontal moving arc to focusing the beam at target center. After 2 decades he composits 201 source of the Co-60 for gamma knife which beams focused at locus. Sveral linac-based stereotactic radiosurgery using the circular collimated beam which size range for 0.4~4.0 cm in a diameter by non-coplanar multiarc have been developed over the decades. The irregular lesions can be treated by superimposing with several spherical shots of radiation over the tumour volume. Linac based techniques include the use of between 4 and 11 non-co-planar arcs and a dynamic rotation technique and use photon beam energies in the range of 6~10 MV. Reviews of the characteristics of several treatment techniques can be found in the literature (Podgorsak 1989, Schell 1991). More in recent, static conformal beams defined by custom shaped collimators or a mini- or micro-multileaf collimator (mMLC) have been used in SRS. Finally, in the last few years, intensity-modulated mMLC SRS has also been introduced. Today, many commercial and in-house SRS programs have also introduced non-invasive immobilization systems include the cyberknife and tomotherapy and proton beam. This document will be compared the characteristics of dose distribution of radiosurgery as introduced gamma knife, BrainLab include photon knife in-house SRS program and cyberknife in currently wide used for a cranial SRS.

CT findings of the Mediastinal tumors (종격동 종양의 전산화단층촬영 소견)

  • Chung, Ho-Son;Lee, Sang-Jin;Son, Mi-Young;Kwon, Hyuk-Po;Hwang, Mi-Soo;Kim, Son-Yang;Chang, Jae-Chun;Park, Bok-Hwan
    • Journal of Yeungnam Medical Science
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    • v.6 no.2
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    • pp.79-90
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    • 1989
  • Computerized Tomography is now well established and important noninvasive method of diagnosting mediastinal mass lesions because of its superior imaging of their size, location and internal composition. Authors ana lysed and present CT findings of 30 surgically proven mediastinal tumors and cysts that were studied and treated at the Yeungnam University Hospital during recent 6 years. The most common tumor was thymona(9 cases), and teratoma(6 cases), lymphoma(6 cases), bronchogenic cyst(4 cases), neurogenic tumor (4 cases), pericardial cyst(1 case) were next in order of frequency. There were 5 cases of thymoma showing homogenous solid density mass, 2 cases were malignant thymoma and myasthenia gravis was present in 2 cases. A case of thymolipoma and a case of thymic carcinoma were included. All teratomas were cystic masses but pathognomic fat, and calcified density were seen only in 4 cases. 5 cases were located in anterior mediastinum and 1 case was in posterior mediastinum. Lymphoma(3 Hodgkin's and 3 non-Hodgkin's) appeared as irregular lobulated mass in anterior mediastinum. Neurogenic tumor(2 ganglioneuroma and 2 neurilemmoma) appeared as homogenous density mass located in posterior mediastinum. Among the 4 bronchogenic cysts, 2 were located in retrotracheal area, 1 was located in subcarinal and 1 was in parathoracic area. One case of pericardial cyst was oval shaped cystic mass located in left pericardiac border.

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Study of the Tidal Discharge (조석출입량에 관한 조사)

  • 최귀열
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.10 no.1
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    • pp.1394-1408
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    • 1968
  • The tidal discharge is defined as the quantity of water flowing through a certain cross-section per unit of time, in contrast to river discharges, tidal discharges change periodically in magnitude and direction. Thus the total volumes of water flowing into again out of the system-called flood volume and ebb volume, respectively, depend on both the tidal and the river discharges. To ditermine the tidal discharge and the flood and ebb volumes of the Yong-san river, the discharges were measured at spring, mean and neap tide and simultaneous gage reading were taken at Samhak-do, Lower Myo-do, Myongsan-ni and Naju. The general procedure for measuring the tidal discharges was as follows. First, several cross-sections were measured and one of them was chosen. First, several cross-sections were measured and one of them was chosen. Then verticals were serected in the chosen cross section. Because comparatively few verticals should be representative of the discharge distribution over the river profile, the selection was done in accordance with the somtimes irregular bottom profile. The velocities were measured with the same current meters. The observations which included water level readings were continued for a period of about 13 hours. The current direction meter, a pyramid shaped resistance body, suspend in the water on a thin wire. The bubble in a circular tilting level fixed to the wire indicates the direction of the current. Reading were taken at intervals of 1m for depths of 10m or less, and for depths over 10m at intervals of 2m, going downwards and upwards. The averages of the two velocities were used for the computation of the discharges. The discharges and the flood and ebb volumes were ditermined by a graphical method. The mean velocities, corrected for their direction when necesary, were ditermined for each time interval and each vertical, and these velocities were plotted against the time. The resulting curves show possible mistakes very clearly, and the effect of observation errors could be reduced. The corrected velocities read from the curve at half-hour intervals were multiplied by the depth at the virtical at the corresponding time. The discharges thus found were ploted against the position of the vertical in the transit and joined by a smooth curve, integration of the curve rendered the total discharges as they occurred of half-hour intervals. Plotting these total discharges against the time yeilded during the day. The flood and ebb volumes were obtained by integration of the total discharge curve.

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Crushing Characteristics of Single Particle of Recycled Aggregate from Waste Concrete (폐콘크리트 순환골재의 단입자 파쇄 특성)

  • Park, Sung-Sik;Kim, Sang-Jung;Moon, Hong-Duk
    • Journal of the Korean Geotechnical Society
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    • v.32 no.12
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    • pp.23-32
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    • 2016
  • A single particle crushing test was carried out for recycled aggregates from waste concrete while demolishing various structures. When the recycled aggregates were used for backfill or road subbase materials, load-displacement and crushing characteristics were analyzed. The recycled aggregates with hydrates and aggregates were sorted into 40 mm size (75-40 mm) and 20 mm size (40-20 mm). At initial loading, their irregular surface was closed to and then crushed by loading plate. Such first crushing stage was called 'Surface crushing'. Further loading, some hydrate was crushed and detached from aggregate, and such process repeated several times. This state is called 'hydrate crushing'. The final state is called 'aggregate crushing' in which aggregate crushed and following load suddenly dropped down. As the load increased, such crushing cycle is repeated several times. The shapes of aggregates are round or square, and triangle or long shaped. Depending on their shapes and surface conditions, they crushed in different ways. The 63% of aggregates showed more than 50% load reduction due to aggregate crushing. The 90% load reduction occurred at 15% of aggregates. The 40 mm aggregate crushed at maximum load between 3.05-4.38 kN and 70% of crushed aggregates were less than 20 mm.

Rapidly and Accurately Processing of Low Melting Block for Shielding of Radiotherapy (방사선(放射線) 치료(治療)의 신속정확(迅速正確)을 위한 저온용융(低溫熔融) 차폐물(遮蔽物)의 제작(製作)과 응용(應用))

  • Chu, S.S.;Lee, D.H.;Park, C.Y.
    • Journal of Radiation Protection and Research
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    • v.4 no.1
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    • pp.14-20
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    • 1979
  • For accurate and easily shielding irregular shaped organ, its minimized penumbra region and a low melting point alloy 'Lead Y' and synchronizing instrument have been developed. The 'Lead Y' is the quaternary eutectic alloy and it is composed of Lead 30.0% Tin 11.5% Bismuth 48 5% Cadmium 10.0% The density of its at $22^{\circ}C$ is $9.8g/cm^3$ and the melting temperature has $40^{\circ}C\;to\;68^{\circ}C$. The thickness of 'Lead Y' for perfect shielding of Co-60 gamma ray and LINAC 10MeV x-ray is 6cm and 7cm respectively. The 'Lead Y' shielding block is casted directly on the styrofoam from which is cut with hot wire of synchronizer device. The special features and advantages of the Lead Y shielding block could be summarized as follows; 1. The shielding block for radiotherapy is rapidly processed only with boiling water and styrofoam. 2. It is not injure one's health and not danger of a fire, because of not generating of any metals vapor and evil smelling. 3. It is very effective to minimize secondary penumbra for the protection of healthy tissue from unnecessary ionizing radiation regardless of the magnification source to skin distance. 4. The HVL of the Lead Y is 1.2cm for Co-60 gamma ray and it's shielding effect is almost same as the pure lead block. 5. The hardness of Lead Y is 1.5 times higher than lead block. 6. It's reavailability is higher than lead block and then one block of Lead Y is reavailable about 30 to 40 times. 7. It is usefull for shielding of x-ray, gamma ray, beta-ray, electron and neutron radiation. 8. The materials for Lead Y are easy to acquire with reasonable price and tractable.

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Practical Virtual Compensator Design with Dynamic Multi-Leaf Collimator(dMLC) from Iso-Dose Distribution

  • Song, Ju-Young;Suh, Tae-Suk;Lee, Hyung-Koo;Choe, Bo-Young;Ahn, Seung-Do;Park, Eun-Kyung;Kim, Jong-Hoon;Lee, Sang-Wook;Yi, Byong-Yong
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.129-132
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    • 2002
  • The practical virtual compensator, which uses a dynamic multi-leaf collimator (dMLC) and three-dimensional radiation therapy planning (3D RTP) system, was designed. And the feasibility study of the virtual compensator was done to verify that the virtual compensator acts a role as the replacement of the physical compensator. Design procedure consists of three steps. The first step is to generate the isodose distributions from the 3D RTP system (Render Plan, Elekta). Then isodose line pattern was used as the compensator pattern. Pre-determined compensating ratio was applied to generate the fluence map for the compensator design. The second step is to generate the leaf sequence file with Ma's algorithm in the respect of optimum MU-efficiency. All the procedure was done with home-made software. The last step is the QA procedure which performs the comparison of the dose distributions which are produced from the irradiation with the virtual compensator and from the calculation by 3D RTP. In this study, a phantom was fabricated for the verification of properness of the designed compensator. It is consisted of the styrofoam part which mimics irregular shaped contour or the missing tissues and the mini water phantom. Inhomogeneous dose distribution due to the styrofoam missing tissue could be calculated with the RTP system. The film dosimetry in the phantom with and without the compensator showed significant improvement of the dose distributions. The virtual compensator designed in this study was proved to be a replacement of the physical compensator in the practical point of view.

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A Case of Metastatic Oral Carcinoma from Rectal Cancer (직장암 유래 전이성 구강 암종의 진단예)

  • Shin, Keum-back;Kang, Kee-hyun;Chae, Gyu-sam
    • Journal of Oral Medicine and Pain
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    • v.24 no.2
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    • pp.171-179
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    • 1999
  • The authors experienced a oral carcinoma involving the medial cortex of the right ramus of mandible and the left side of the maxilla which was metastasized from primary rectal adenocarcinoma based on the comprehensive evaluation of data obtained from (1) the past medical history of primary rectal adenocarcinoma, (2) the computerized tomographic views of the homogeneous mass on the anteromedial region of the right ramus of mandible destructing the medial cortex of the right ramus of mandible, and the irregular mass around the clivus spreading into the sphenoid sinus and destructing the left side of the maxilla ; the bone scanning of hot spots on the nasal region and the left side of maxilla ; the posteroanterior chest radiographic view of multiple nodular radiopacities on the lung, (3) the retrospective review of the sonographic view of a hypoechoic, well-demarcated, target-like mass with central hyperechoic focus on right lobe of liver in a Korean female of 49-year-old who complained the ptosis of left eyelid, the swelling on left zygomatic area, the left facial paralysis, the facial asymmetry and a round-shaped, elevated lesion with a hematoma on the mucosa covering the right ramus of mandible.

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Reconstruction of body contour with digital camera image (Digital Camera의 영상을 이용한 신체 단면도 제작)

  • Kwon, KT;Kim, CM;Kang, TY;Park, CS;Song, HK
    • The Journal of Korean Society for Radiation Therapy
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    • v.15 no.1
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    • pp.53-60
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    • 2003
  • I. Purpose It is essential to have the correct body contour information for the calculation of dose distribution. The role of CT images in the radiation oncology field has been increased. But there still exists a method to use cast or lead wire for the body contour drawing. This traditional method has drawbacks such as in accurate and time consuming procedure. This study has been designed to overcome this problem. II. Materials and Methods A digital camera is attached to a pole which stands on the opposite side of the gantry. Positional information was acquired from an image of the phantom which is specially designed for this study and located on the isocenter level of the simulator Laser line on the patients skin or on the phantom surface was digitized and reconstructed as the contour. Verification of usefulness this technique has been done with various shape of phantoms and a patients chest III. Results and Conclusions Contours from the traditional method with the cast or lead wire and the digital image method showed good agreement within experimetal error range. This technique showed more efficiente in time and convenience. For irregular shaped contour, like H&N region, special care are needed. The results suggest that more study is needed. To use of the another photogrammatory techinique with two camera system may be better for the actual clinical application

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Effect of Carrageenan-Induced Pain on Lower Limb Muscle and Ligament of Rat (Carrageenan에 의한 근통유발이 백서의 하지근과 인대에 미치는 영향)

  • Lee Gun-Hyee;Hwang Byung-Chun;Choi Jeong-Son;Kim Yang-Jung;Yun Ju-Young;Lee Geon-Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1356-1362
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    • 2005
  • The purpose of this study os to investigative the effect of Carrageenan-Induced Pain on lower limb muscle and ligament of rat. To evaluate pain mechanism in muscle and ligament, pain was induced by the injection of 2% $0.1m{\ell}$ carrageenan into the left lower limb muscle of rats after rats were anesthesized with 3% enflurane. Rats were killed on 72 hours after pain induction under the anesthesia. anterior rectus femoris muscle and its ligament were removed from rat hind limb. Morphological changes of them were peformed by the observation of light and electron microscopes. In the light microscopic findings, the muscle cells were polyheadral and situated with each other without small gap in control group. nucleus of cell was seen along the cell margin, and muscle cell groups were divided by regular narrow gap in cross section. In the pain-induced group, muscle cell groups were divided each other by the irregular gap, and some of groups formed larger than other cell groups by the fusion. Intercellular gap of most cell groups were increased compared with control groups. And also, perimysium of muscle cell groups was swollen in cross section. In control group, muscle cells contacted each other closely and each cell was divided by perimysium. The intracellular gaps were not seen between myofibrills, and also striations were well defined between muscle cells in longitudinal section. In pain-induced group, muscle cells were divided by the small intracellular gaps. And also, muscle cell showed many a short cross or longitudinal intercellular gaps in longitudinal section. In light microscopic findings of control group, tendon was composed with many tendon fibers contacted each other closely without gap. The free margin of tendon was fused, and apso the tendon fibers did not invaded between muscles. In pain-induced group, tendon was divided small groups by intertendinous gap, and also the margin of tendon divided by small groups. In the free margin, tendon invaded into muscle cells, and also fibroblasts between tendon fibers were long and lance-shaped. From these results, it is suggested that pain induction by carrageenan injured rat skeletal muscle and ligament by the morphological changes.

Comparison of Super Structure-Sub Structure Separation Analysis and Unification Analysis about Building Structures (건축구조물의 상부구조-하부구조 분리해석과 일체해석의 비교분석)

  • Kim, Jae-Yo;Kim, Jin-Yong;Kang, Su-Min
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.29 no.1
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    • pp.19-28
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    • 2016
  • In the case of structural analysis for building structures, the super-structure and the sub-structure are analyzed by using separate structural models in the field because of time saving, facile result interpretation and easy analysis of dynamic behavior. However this separate structural model violated the compatibility condition of structural analysis and it can not consider the interaction of superand sub- structures. In the present study, the analysis results of this separate model were compared to those of the unified model of super- and sub- structures which can consider the interaction of super- and sub- structures and reflect the realistic boundary conditions. According to the comparison results, the the analysis model using separate models can underestimate the member force and deflection of structural members in the super-structures and overestimate the deflection and member force of sub-structures. Therefore, in the case of high-rise buildings, irregular shaped buildings, buildings which are expected to be affected by large differential settlement and remodeling buildings, the unified structural model for super- and sub- structures was recommended for structural analysis instead of the separate structural model.