• Title/Summary/Keyword: Iron availability

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Effect of Recombinant Human Erythropoietin in the Anemia of Prematurity : a Pilot Study (미숙아 빈혈에 대한 Recombinant Human Erythropoietin의 효과 : 예비연구)

  • Lee, Kyung-Ah;Shin, Soon-Moon;Park, Yong-Hoon;Hah, Jeong-Ok
    • Journal of Yeungnam Medical Science
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    • v.11 no.1
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    • pp.115-126
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    • 1994
  • The recent availability of recombinant human erythropoietin has opened new perspectives in the management of a variety of anemias. Clinical trials have been initiated in several countries using different approaches and methodology. We randomly assigned twelve premature infants(gestational age < 32 week) at high risk of requiring erythrocyte transfusion for anemia of prematurity with either subcutaneous recombinant human erythropoietin or a placebo. Treatment with rHuEPO was initiated at a dose of 100 units/kg day for 3 days a week. All patients were given supplemental oral iron therapy at a dose of 3 mg/kg per day, as tolerated and oral vitamin E at a dose of 25 units per day. Treated and control babies did not differ with respect to weight, hematocrit, overall mean reticulocyte count or rate of growth respectively. However, reticulocyte counts increased earlier in patients given rHuEPO. We conclude that rHuEPO administration is safe and feasible at the dose studied.

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Cadmium Tolerance in Alfalfa is Related to the Up-regulation of Iron and Sulfur Transporter Genes along with Phytochelatin Accumulation

  • Lee, Ki-Won;Lee, Sang-Hoon;Song, Yowook;Ji, Hee Jung;Choi, Bo Ram;Lim, Eun A;Rahman, Md Atikur
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.40 no.3
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    • pp.190-195
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    • 2020
  • Cadmium (Cd) toxicity is a serious limitation for agricultural production. In this study, we explored tolerance mechanism associated with Cd toxicity tolerance in alfalfa plants. We used three distinct alfalfa cultivars M. sativa cv. Vernal, M. sativa cv. Zhung Mu, and M. sativa cv. Xing Jiang Daye in this study. Cd showed declined chlorophyll score in Xing Jiang Daye compared with Zhung Mu and Vernal. No significant change observed among the cultivars for root and shoot length. Atomic absorption spectroscopy analysis demonstrated a significant accumulation of Cd, Fe, S and PC in distinct alfalfa cultivars. However, Zhung Mu and Xing Jiang Daye declined Cd accumulation in root, where Fe, S and PC incremented only in Zhung Mu. It suggests that excess Cd in Zhung Mu possibly inhibited in root by the increased accumulation of Fe, S and PC. This was further confirmed by the response of Fe (MsIRT1) and S transporters (MsSULTR1;2 and MsSULTR1;3), and MsPCS1 genes associated with Fe, S and PC availability and translocation in roots and shoots. It suggests that specially the transcript signal inducing the responses to adjust Cd especially in Zhung Mu. This finding provides the essential background for further molecular breeding program for forage crops.

OPTIMIZATION OF DIETS WITH EQUAL QUALTITY OF PROTEIN DERIVED FROM FOOD LEGUME AND CEREAL FOR HARD WORKING RURAL POOR USING PROGRAMMING APPOACH

  • Kulkarni, S.D.;Bhole, N.G.;Sawarkar, S.K.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.637-647
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    • 1993
  • Over 40 per cent Indian population needs to be attended for nutritional improvement. Traditional nutritious food resources though abundantly available but presently less used, if incorporated in the diets, can yield low-cost nutritionally balanced diets. The linear programming (LP)model was used for optimization of food resources to satisfy protein -energy requirements of hard working rural poor. Soybean-a highly nutritious food legume-available at reasonably low price was included along with chick -pea and pigeon -pea for comparison .The three cereals predominantly used in Indian diets -rice, wheat and sorghum -and three typical leafy vegetables namely, spinach , drumstick leaves and rajagira (Amaranths paniculantus) leaves were used for optimization . The contribution of food legume was restricted to supply only 50 per cent of daily protein requirement for maximum protein value. The quantities of other food stuffs namely , milk , sugar , tubers etc. were restricted to nati nal per capita availability. the nutrition satisfaction levels in per cent RDA by the model are 149-250 for protein , 51-106 for fat, 134-362 for iron an d143-1158 for Vitamin-A. Quantities of food legumes, cereals and leafy vegetables ranged from 289-601, 3000-3700 and 360-1200 g/day respectively for a reference family of five hard working rural poor. Daily food resources cost ranged from US$ 0.6 to 1.0 for the family. Amongst food legumes, soybean based diet combinations provide maximum nutritional benefits at minimum cost indicating its suitability for wider adoption by hard working poor.

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Community Structure, Phytomass, and Primary Productivity in Thuja orientalis Stands on Limestone Area

  • Kwak, Young-Se;Lee, Choong-Il
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.3 no.3
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    • pp.189-196
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    • 1999
  • The community structure, phytomass, and primary productivity in Thuja orientalis stands on a limestone area located in Maepo-up, Chungbuk province in Korea were estimated quantitatively. Seven species including a small proportion of Quercus dentata were identified in the tree layer, 26 species including Ulmus macrocarpa in the shrub layer, and 79 species including Carex lnceolata in the herb layer of the Thuja stands. The vertical distribution of the fine root phytomass exhibited a power functional decrease relative to the soil depth. The seasonal changes in the fine root phytomass at a soil depth of 5 cm were closely related to the pecipitation in the study area. The productivity of the stand of stems, branches, leaves, and roots were 10.72, 0.82, 0.45 and 6.46 ton DM. $ha^{-1}$ .$yr^{-1}$, respectively. The Thuja stand had a high foliage(25%) and low rate of production per unit of foliage. The annual turnover rate of the fine roots int he Thuja stand was 6.71 $yr^{-1}$. The net primary production of the overstory including the understory was estimated at 19.48 ton DM.$ha^{-1}$.$yr^{-1}$ including an underground section of 6.46 ton DM.$ha^{-1}$.$yr^{-1}$(33%). The allocation ratio of net production to root was lower in the limestone Thuja communities than at the nearby non-limestone ones, whereas the production efficiency to leaf weight was higher in the limestone communities. These results would seem to indicate that the limited production capacity is due to the calcium toxicity and low availability of iron and phosphorus in a limestone soil with a high pH, calcium, and bicarbonate content with a strategy for survival in a hostile habitat.

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Recombinant Human Erythropoietin Therapy for a Jehovah's Witness Child With Severe Anemia due to Hemolytic-Uremic Syndrome

  • Woo, Da Eun;Lee, Jae Min;Kim, Yu Kyung;Park, Yong Hoon
    • Clinical and Experimental Pediatrics
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    • v.59 no.2
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    • pp.100-103
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    • 2016
  • Patients with hemolytic-uremic syndrome (HUS) can rapidly develop profound anemia as the disease progresses, as a consequence of red blood cell (RBC) hemolysis and inadequate erythropoietin synthesis. Therefore, RBC transfusion should be considered in HUS patients with severe anemia to avoid cardiac or pulmonary complications. Most patients who are Jehovah's Witnesses refuse blood transfusion, even in the face of life-threatening medical conditions due to their religious convictions. These patients require management alternatives to blood transfusions. Erythropoietin is a glycopeptide that enhances endogenous erythropoiesis in the bone marrow. With the availability of recombinant human erythropoietin (rHuEPO), several authors have reported its successful use in patients refusing blood transfusion. However, the optimal dose and duration of treatment with rHuEPO are not established. We report a case of a 2-year-old boy with diarrhea-associated HUS whose family members are Jehovah's Witnesses. He had severe anemia with acute kidney injury. His lowest hemoglobin level was 3.6 g/dL, but his parents refused treatment with packed RBC transfusion due to their religious beliefs. Therefore, we treated him with high-dose rHuEPO (300 IU/kg/day) as well as folic acid, vitamin B12, and intravenous iron. The hemoglobin level increased steadily to 7.4 g/dL after 10 days of treatment and his renal function improved without any complications. To our knowledge, this is the first case of successful rHuEPO treatment in a Jehovah's Witness child with severe anemia due to HUS.

A Study on the Changes of Hairstyle by the Development in Hairdressing Industry in Korea - With the Focus on Women's Hairstyle -

  • Na, Yun-Young;Yoon, Jeom-Soon
    • Journal of Fashion Business
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    • v.6 no.3
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    • pp.41-51
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    • 2002
  • The author of the paper investigated the changes of hairstyle along the developments in hairdressing industry in the 20th century. The development process of hairdressing industry was divided into four periods of introduction, origination, growth, and establishment. The corresponding changes of hairstyle were analyzed and the findings are as follows. 1. Hairstyle could be classified into such typical ones as traditional style, cut, bob, wave, permanent wave, up style, and hair coloring. 2. Fashion leaders affected the changes of hairstyle. 3. Whenever hairdressing appliances were introduced, new hairstyle was practiced as follows with the use of the appliances. (1) Introduction Period - Traditional Style : Chignon, pigtail ribbon $\rightarrow$ Variations were designed in hair length or split due to the limited availability of appliances. - Up Style : Pompadour, thick and up hair, encircling hair $\rightarrow$ Padding was used for sweep-up. (2) Origination Period - Bob Style : Women's first bob style. - Wave style : Wave with bob, close-cropped hair, up style $\rightarrow$ Iron, set, permanent devices were used. (3) Development Period - Wave Style : Wind wave, easily manageable wave $\rightarrow$ Blow dry, body permanent were used. (4) Establishment Period - Straight Style : Use of straight permanent. - Thick Wave Style : Development of various kinds of rod. - Hair Coloring : Advent of diverse fashion hair coloring, apart from the coloring of white hair, with the introduction of color TV. - Bob Style : Romantic bob style $^{\circ}\hat{E}$ Use of clippers and thinning scissors. Thus, the changes of hairstyle according to the development in hairdressing industry had close relationship with the improvement in hairdressing appliances.

The Effect of Fermentation of Soybeans on the Protein and Mineral Bioavailability in the Rats (대두의 발효가 흰쥐의 단백질 및 무기질의 생체 이용율에 미치는 영향)

  • Bai, Young-Hee;Yoon, Sun
    • Journal of Nutrition and Health
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    • v.18 no.2
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    • pp.139-146
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    • 1985
  • This study was attempted to investigate the effect of fermentation of soybean on protein and mineral bioavailability. The traditional, oriental fermented soybean foods, Meju and Tempeh, and isolated soybean protein( ISP ) and cooked soybean were prepared and fed to rats as sources of protein. The C-PERs of ISP, cooked soybean, Meju and Tempeh were 1.82, 1.98, 2.11, and 2.36, respectively C-PERs of fermented soybean products, Meju and Tempeh were higher than ISP and cooked soybeans. However, they were not significantly different The percent retention of protein of rats fed with casein, ISP, cooked soybean, Meju and Tempeh were 47.44%, 51.83%, 47.67%, 50.90% and 45.97%, respectively, showing no significant differences among the diets. The rates of calcium retention percent were 62.26%, 59.22%, 61.59%, 55.78% and 67.09 % in rats fed with casein, ISP, cooked soybean, Meju and Tempeh, respectively, demonstrating no significant differences. Rats fed with cooked soybeans did show significantly higher iron retention rate than other samples. However, this study failed to any significant increase in iron availability. The percent of fine retained in rats fed with ISP was significantly lower than those of rats fed with other diets, however, significantly high amounts of zinc were retained in rats fed with Tempeh compared with other diets. The percents of zinc, iron, calcium retained in the bones of rats were not significantly different among the diets.

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Environmental Leachability of Electric Arc Furnace Dust for Applying as Hazardous Material Treatment (제강분진을 이용한 유해물질 처리기술 적용을 위한 안전성 평가)

  • Lee, Sang-Hoon;Kang, Sung-Ho;Kim, Jee-Hoon;Chang, Yoon-Seok
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.3
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    • pp.329-336
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    • 2006
  • Iron manufacturing process involves production of various by-product including slag, sludge, sintering and EAF(Electric Arc furnace dust). Some of the by-products such as EAF and sintering dust are disposed of as waste due to their high heavy metal contents. It has been notice for many years that the EAF dust also contain about 65% of Fe(0) and Fe(II) and then the possible utilization of the iron. One possibility is to apply the EAF as a lining material in conjunction with clay or HDPE liners, in waste landfill. The probable reaction between the leachate containing toxic elements such as TCE, PCE dioxine and $Cr^{6+}$ is reduction of the toxic materials in corresponding to the oxidation of the reduced iron and therefore diminishing the toxicity of the leachate. It is, however, prerequisite to evaluate the leaching characteristics of the EAF dust before application. Amelioration of the leachate would be archived only when the level of toxic elements in the treated leachate is less than that of in the untreated leachate. Several leaching techniques were selected to cover different conditions and variable environments including time, pH and contact method. The testing methods include availability test, pH-stat test and continuous column test. Cr and Zn are potentially leachable elements among the trace metals. The pH of the EAF dust is highly alkaline, recording around 12 and Zn is unlikely to be leached under the condition. On the contrary Cr is more leachable under alkaline environment. However, the released Cr should be reduced to $Cr^{3+}$ and then removed as $Cr(OH)_3$. Removal of the Cr is observed in the column test and further study on the specific reaction of Cr and EAF dust is underway.

Chemical Composition and Biological Feed Value of Autoclaved Poultry By-products for Poultry (가압열처리한 도계부산물의 화학적 조성과 닭에 대한 생물학적 사료가치)

  • 이규호
    • Korean Journal of Poultry Science
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    • v.24 no.4
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    • pp.185-191
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    • 1997
  • In order to obtain the basic information needed to utilize poultry by-products as feed resources, the yielding ratio, chemical composition and nutrient bioavailability of 5 offal components such as autoclaved head, feet, viscera, blood and feathers were investigated. Yielding ratios of head, feet, viscera, blood and feathers were 2.93% 4.78%, 10.98%, 3.91% and 4.83%, respectively. The crude protein contents of feathers (86.71%) and blood (82.99%) were higher than those of viscera (64.67%), feet (58.76%) and head (49.51%) , Inversely, the crude fat contents of blood (6.96%) and feathers (2.96%) were lower than those of head (26.19%), viscera (23.96%) and feet (13.73%). The crude ash contents of feet (21.69%) and head (20.38%) were higher than those of other by-products (0.96∼8.62%). The macro-mineral contents of head and feet were higher than those of other components, and the iron content of blood was higher than the other by-products. The total amino acid contents of poultry by-products showed the same trend as the crude protein contents. In addition, the Iysine content of feathers was very low compared to its high protein content. The essential amino acid contents of feathers were poorer than those of other offal components. Among the 5 offal components, the feathers showed the poorest amino acid availabilities. The ME contents were highest in viscera, and head, blood, feathers and feet. in decreasing order.

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Increased Available Phosphate by Shell Meal Fertilizer Application in Upland Soil (밭 토양에서 패화석비료 시용에 따른 유효인산의 증대)

  • Lee, Chang-Hoon;Lee, Ju-Young;Ha, Byung-Hyun;Kim, Pil-Joo
    • Korean Journal of Soil Science and Fertilizer
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    • v.38 no.1
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    • pp.52-57
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    • 2005
  • Previous studies showed that shell meal fertilizer from the oyster farming industry could be a potential inorganic soil amendment to increase Chinese cabbage productivity and to restore the soil nutrient balance in upland soil (Lee et al., 2004). Herein, shell meal fertilizer was applied at rates of 0, 4, 8, 12, and $16Mg\;ha^{-1}$ to upland soil (Pyeontaeg series, Fine silty, Typic Endoaquepts) for Chinese cabbage cultivation. We found available phosphate increased significantly with shell meal fertilizer application, due to high content of phosphate ($1.5g\;P_2O_5\;kg^{-1}$) in the applied shell meal fertilizer. In addition, high pH of shell meal fertilizer contributed to increase available phosphate content by neutralization of acidic soil. Total and residual P contents increased significantly with increasing shell meal fertilizer application, but we could not find any tendency in organic and inorganic P fraction. Of extractable P fraction, water-soluble phosphorus (W-P) and calcium-bound P (Ca-P) contents increased significantly with increasing application level. By contrast, aluminum and iron-bound P (Al-P and Fe-P) decreased slightly with shell meal application. The present experiment indicated that shell meal fertilizer had a positive benefit on increasing available phosphate content in arable soil. And so the increased available phosphate by shell meal fertilizer may decrease phosphate application level and then reduce phosphorus loss in arable soil.