• Asian-Australasian Journal of Animal Sciences
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• v.17 no.9
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• pp.1266-1270
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• 2004

Humic substances include several biological active and inactive compounds that are commonly used for improving soil fertility. Use of humic substances in swine diets is a novel concept. Humic substances contain 8,700 mg/kg of iron but its bioavailability is unknown. This study was conducted to test the bioavailability of iron in humic substances for nursery pigs. One hundred twenty five pigs (Newsham, Colorado Springs, CO) were not given supplemental iron while nursing for 21 d. Pigs were weaned on d 21 and allotted to one of five treatments (four control treatments with different levels of supplemented iron; 0, 30, 70 and 88 mg/kg from ${FeSO}_4$ and one treatment with 70 mg/kg iron from humic substances). Pigs were fed diets for 5 wk ad libitum and water was accessible freely. Body weight and feed intake were measured weekly. Blood samples were taken from pigs on d 28 to measure the number of red blood cells and hemoglobin concentration. Pigs fed a diet with the humic substances grew faster (p<0.05) during the first week postweaning, but performance was not different during the entire 5 wk period. Feed intake and gain/feed were the same among treatments. The slope ratio technique was used to estimate relative iron bioavailability. The concentration of blood hemoglobin did not respond to dietary iron levels using this model. However, the number of red blood cells (106/$\mu$l) was modeled by 4.438+0.017${\times}$ 'ron (mg/kg) from ${FeSO}_4$'0.012${\times}$'ron (mg/kg) from the humic substances' Based on the comparison between the slopes (0.012 from humic substances and 0.017 from ${FeSO}_4$), iron in humic substances was 71% as available as the iron in ${FeSO}_4$. The slopes for dietary feed intake of ${FeSO}_4$ and the iron in humic substances did not differ (p>0.05). Humic substances can replace ${FeSO}_4$ as an alternative iron source for pigs at 71% relative bioavailability.

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.1
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• pp.107-113
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• 1993

This study determined the concentrations of micro-minerals in pastures, in feed supplements and in grazing, reproducing ewes, at different times during the year, at three farms in Northern China. Samples were collected 5 to 8 times during the year and analysed for selenium, copper, iron, molybdenum and zinc. On two farms selenium concentrations in both pastures and animal tissues were low for part of the year. The lowest concentrations in pasture (< $30{\mu}g/kg$ DM) and liver (< $100{\mu}g/kg$ wet weight) indicated that productivity of the sheep may be reduced by a deficiency of this element. On one farm copper concentrations in the lever were in the liver were in the deficient range (< $5{\mu}g/kg$ wet weight) for part of the year. It is likely that this is a result of high intakes of iron from pasture (up to 4.5 g Fe/kg DM) and soil, as indicated by high concentrations of iron in faeces (up to 7 g Fe/kg DM). Molybdenum intake is unlikely to have had much influence on copper absorption because pasture concentrations of this element were not unusually high (1 to 5 mg/kg DM). Zinc in pastures on two farms was below 10 mg/kg DM for part of the year. On one of these farms, the concentration of zinc in faeces was below 30 mg/kg DM throughout the year and this is consistent with zinc intakes of 7 to 15 mg/kg. Despite these low intakes, the concentratons of zinc in plasma were consistently above deficient levels. No clinical signs of deficiencies of any of the elements studied were observed.

• Journal of architectural history
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• v.16 no.3
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• pp.95-114
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• 2007

Since the 17th century, the society of Joseon dynasty belongs to a period of rapid transition in many fields. As the building is a result to be produced on the basis of a society and economy, the general transition in a society is to be reflected into a process of building construction. Especially, a study on the material supply system of economic base in a process of building construction is one of vely important factors in an understanding or estimate of a building. On the premise, this paper is to examine the supply system of iron materials and the tools in the construction of the government managed buildings in the late of Joseon dynasty on a viewpoint of productivity. Construction reports and other documents in those days are examined for the study. Following conclusions have been reached through the study. 1) The general supply method of iron materials for a large-scale government construction was based on 'byulgong', that is, a kind of tribute. 2) Various methods were selected in the supply method of iron materials for government use in the late of Joseon dynasty. The priority order of choice in its government policy was put on an easiness of amount security, on a minimum of expenditure, and on an efficiency of construction execution. 3) The manufacturing technique of weaponry was used in the production method of iron materials and the tools for government use. The cooperation of the official, the army, and the merchant had improved the manufacturing technique of building construction.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.6
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• pp.1020-1026
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• 1994

Pseudomonas plycolor was used to investigated the optimal culture condition to examine the various properties of superoxide dismutase (SOD). this SOD was inhibited by $H_2O_2$, azide ion, but not by cyanide ion. This result indicates that the enzyme might be a Fe-SOD. The composition of optimal culture medium for the enzyme production was 3% of glycerin, 1% of polypeptone, 0.5% of meat extract, 0.2% of KCI and the initial ph was 9.0 . The cultivation for the enzyme production was carried out in 500ml shaking flask containing 100ml of the optimal medium at $30^{\circ}C$ on a reciprocal shaker. The enzyme production reached maximum at 15hrs of cultivation and then declined sharply afterward.

• Journal of Korea Foundry Society
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• v.17 no.3
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• pp.286-291
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• 1997

Influence of Si contents on the mechanical properties and microstructure of austempered ductile iron was investigated. Four different Si contents between 2.0 and 2.9% were used. Austenitizing was performed at $890^{\circ}C$ for 2 hrs and austempering temperatures were both 340 and $380^{\circ}C$ for 0.5, 1, and 2 hrs. Nodule content was more than $300/mm^2$ and nodularity was more than 90%. Microstructure was revealed using nital and retained austenite was measured by x-ray diffractometer. Tensile test, no-notch Charpy impact test and wear test were performed. Tensile strength was improved as Si content increased and both elongation and impact toughness had peak at 2.6%Si. The specimen austempered at $380^{\circ}C$ showed lower tensile strength than that of $340^{\circ}C$, but showed higher elongation. However, austempering temperature of $380^{\circ}C$ was desirable because that of $340^{\circ}C$ was close to lower bainite transformation. As austempering time increased, tensile strength and elongation were improved and optimum condition was obtained for 2 hrs heat treatment.

• Asian-Australasian Journal of Animal Sciences
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• v.3 no.2
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• pp.103-106
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• 1990

A balance study was conducted to determine the requirements of iron, copper, cobalt and manganese in crossbred calves. Six calves were fed milk average 10 percent of their body weight and were supplemented with 15 g mineral mixture daily. A balance trial was conducted at $2\frac{1}{2}$ months of age. The primary route of excretion was through digestive tract as 99.87, 80.99, 77.27 and 99.94 percent of Fe, Cu, Co and Mn were excreted through faeces. The requirements of Fe, Cu, Co and Mn were computed using the respective mineral balance data and were found to be 169.60, 7.20, 4.48 and 8.89 mg/kg respectively.

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.688-691
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• 2000

Ferritin, an iron-storage protein, is found in bacteria and some animal tissues such as liver, spleen, and bone marrow. It is more effective and causes less side reactions than the traditional ferrous sulfate, and thus has been used primarily to treat iron deficiency in pregnancy anaemia. Currently, the ferritin extracted from the bovine and equine spleens are sold as a commercial product. Its market is estimated as several hundreds of million US dollars. However, because of the recent warnings against the viral diseases of animal origins such as mad cow disease, a safer ferritin is sought after. Our research team has successfully developed a production process for recombinant human ferritin. Its expression titer from yeast is high enough to be economically viable, and its particle formation characteristics are as effective as well.

• Journal of Yeungnam Medical Science
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• v.34 no.2
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• pp.174-181
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• 2017

Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic cell death. This type of cell death is characterized by mitochondrial shrinkage with an increased mitochondrial membrane density and outer mitochondrial membrane rupture. Ferroptosis can be induced by a loss of activity of system $X_c{^-}$ and the inhibition of glutathione peroxidase 4, followed by the accumulation of lipid reactive oxygen species (ROS). In addition, inactivation of the mevalonate and transsulfuration pathways is involved in the induction of ferroptosis. Moreover, nicotinamide adenine dinucleotide phosphate oxidase and p53 promote ferroptosis by increasing ROS production, while heat shock protein beta-1 and nuclear factor erythroid 2-related factor 2 inhibit ferroptosis by reducing iron uptake. This article outlines the molecular mechanisms and signaling pathways of ferroptosis regulation, and explains the roles of ferroptosis in human disease.

• Journal of Korea Foundry Society
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• v.3 no.4
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• pp.248-255
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• 1983

The effect of chromium, aluminium and copper contents on the structures and mechanical properties of cast iron was investigated. 1) Mechanical properties were improved with the formation of ledeburite by chromium addition. The primary carbides dispersed in martensitic matrix contributed to high strength and wear resistance. 2) Small addition of aluminium decreased hardness of the cast iron. 3) The impact values were decreased by the formation of the double carbides but improved by the heat treatment. 4) Small addition of copper up to a certain level increased the hardness. Also impact values were considerably increased.

• Korean System Dynamics Review
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• v.10 no.1
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• pp.61-76
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• 2009

We try to use system dynamics to forecast the demand/supply and price, also transportation fare for iron ore. Iron ore is very important mineral resource for industrial production. The structure for this system dynamics shows non-linear pattern and we anticipated the system dynamic method will catch this non-linear reality better than the regression analysis. Our model is calibrated and tested for the past 6 year monthly data (2003-2008) and used for next 6 year monthly data(2008-2013) forecasting. The test results show that our system dynamics approach fits the real data with higher accuracy than the regression one. And we have run the simulations for scenarios made by possible future changes in demand or supply and fare related variables. This simulations imply some meaningful price and fare change patterns.