• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.6
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• pp.1538-1542
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• 2003

This Study was carried out for proof of confidence of Iris Diagnosis. We analyzed relation between Iris Signs and Chief Complain, and then analyzed relation between Iris Signs and Past History. The rate of relation between Iris Signs and Chief Complain was 72.1 %. The rate of relation between Iris Signs and Past History was 52.9%. synthetically, We had known that this diagnosis method have probability of 79.7%. It was confirmed that there are close correlations between Iris Signs and Chief Complain and between Iris Signs and Past History.

• Journal of the Korea Society of Computer and Information
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• v.13 no.6
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• pp.87-94
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• 2008

Iris diagnosis is an alternative medicine technique whose proponents believe that patterns, colors, and other characteristics of the iris can be examined to determine information about a patient's systemic health. However, because most of previous studies only find a sign pattern in a gray iris image, they are not enough to be used for a iris diagnosis system. In this paper, we developed an iris diagnosis system based on a color image processing and iris medical information stored in database. The system includes four modules : input module with an iris camera, iris signs extraction module, medical database, output module with printing. Based on a color image processing approach, this paper presents the extraction algorithms of 7 major iris signs and correction manually for improving the accuracy of analysis. We can use the iridology and patient's health DB in the stage of signs analysis. Compared with the existing system, the developed system can be applied to an iris diagnosis system since it provides various additional functions.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.1
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• pp.107-114
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• 2017

Iris diagnosis is an alternative medicine to diagnose the disease of the patient by using different of the iris pattern, color and other characteristics. This paper proposed a disease prediction algorithm that using the iris regions that analyze iris change to using differential image of iris image. this method utilize as patient's health examination according to iris change. Because most of previous studies only find a sign pattern in a iris image, it's not enough to be used for a iris diagnosis system. We're developed an iris diagnosis system based on a iris images processing approach, It's presents the extraction algorithms of 8 major iris signs and correction manually for improving the accuracy of analysis. As a result, PNSR of applied edge detection image is about 132, and pattern matching area recognition presented practical use possibility by automatic diagnostic that presume situation of human body by iris about 91%.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.5
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• pp.971-980
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• 2023

Safety accidents and industrial accidents are constantly occurring in existing industrial sites. In addition, the probability of accidents occurring due to physical and mental fatigue of workers is increasing. Accordingly, it is required to introduce systematic management and various systems for the safety of workers. In this paper, by developing an access control system using bio-metric information at industrial sites, we develop efficient health management and access control management functions for workers. Workers are identified through face recognition for access control, and health status is determined through iris recognition. It aims to improve accuracy and develop a more efficient management system by diagnosing signs of health abnormalities through the congestion of the iris and eyes of workers. Finally, the contents of the development consist of an on-site access control system, an access control program for administrators, and a main server system that diagnoses signs of abnormal health of users.

• Journal of Yeungnam Medical Science
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• v.34 no.1
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• pp.11-18
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• 2017

The pupillary size and movement are controlled dynamically by the autonomic nervous system; the parasympathetic system constricts the iris, while the sympathetic system dilates the iris. Under normal conditions, these constrictions and dilations occur identically in both eyes. Asymmetry in the pupillomotor neural input or output leads to impaired pupillary movement on one side and an unequal pupil size between both eyes. Anisocoria is one of the most common signs in neuro-ophthalmology, and the neurological disorders that frequently cause anisocoria include serious diseases, such as vascular dissection, fistula, and aneurysm. A careful history and examination can identify and localize pupillary disorders and provide a guide for appropriate evaluations.

• Journal of Veterinary Clinics
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• v.36 no.4
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• pp.212-218
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• 2019

This study evaluates the drug delivery and biocompatibility of latanoprost imbedded disk in rabbit eye by assessing pharmacokinetics (PK), clinical signs, and histopathologic findings. During 84 days of experimental period, 48 New Zealand Rabbit (NZW) eyes were divided into control group which received no treatment and test material group which latanoprost were implanted intrasclerally. Pharmacokinetic assessment was performed to evaluate the drug delivery for 3 months. For biocompatibility, clinical signs were observed and histopathological analysis was done at 3 months post-operatively. The concentration of latanoprost in the iris tissue was maintained during the experimental period and the highest level of latanoprost was found at 4 weeks. However, the latanoprost was not found in the aqueous humor. Macroscopically, there was no evidence of clinical signs except for temporary hyperemia, neovascularization and edema immediately after surgery. On histopathological examination, there were no abnormal findings such as hyperemia, neovascularization, and edema in the eye tissues. The latanoprost imbedded disks has effectively released the drug into the adjacent tissue with high compatibility. Therefore, this study suggests that the drug delivery system with intrascleral latanoprost imbedded implants might be a novel approach as a treatment option for glaucoma.

• Journal of Veterinary Clinics
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• v.29 no.6
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• pp.435-440
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• 2012

This study was designed to evaluate the clinical efficacy and safety of Rhubarb extracts ($Rubenal^{(R)}$) in dogs with chronic renal failure (CRF). Client-owned 40 dogs with CRF graded International renal interest Society (IRIS) II-III were enrolled in this study. The dogs were equally allocated and blindly administered with $Rubenal^{(R)}$ or placebo. The following items were evaluated at day 0, 30, 90 and 180: body condition score (BCS), clinical score (appetite, polydipsia/polyuria, quality of life score), hemogram (WBC, RBC, PCV), serum biochemistry (ALT/AST, ALP, Creatinine/BUN, total protein, albumin), serum electrolyte (Na, K, Cl, Ca, P), systolic blood pressure, urinalysis (UPC, USG) and IRIS stage. In this study, we found that the $Rubenal^{(R)}$ preparation was well tolerated by dogs and induced no adverse effects. Statistically significant improvements were observed in clinical score (quality of life score by vet and clients), serum BUN and creatinine levels, serum phosphorus concentration, level of proteinuria, and the IRIS score of CRF in dogs after 6 month of treatment of $Rubenal^{(R)}$. Those findings suggested that the Rhubarb extracts can improve the clinical signs of CRF (i.e. azotemia, hypertension, proteinuria, hyperphosphoremia) and the quality of life (i.e. BCS, clinical score) and can retard the progression of CRF in dogs. Therefore the Rhubarb extracts can be a good supplementary drug for treating dogs with subclinical and clinical renal diseases. However, care should be taken for interpreting our result, because this study is not double-blinded controlled study but pilot study.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.305-314
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• 1997

This study was purposed to observe the advantages obtained from iridodiagnostics and automatic iridoscope or oriental medical doctors. In order to study the iridodiagnostics, 5 case-researches were made as the first step. The results were obtained as follows. 1. First of all, the formation of darkening area must be paid attentionally with toxic spot and lacunain relation to the interpretation of present illness. 2. The theoretical concepts about structure in iridodiagnostics and oriental medicine were same. 3. The constitutional type of iridodiagnostics played a important role in concluding the nature and background of symptoms. 4. Most of iris signs reflected the histological changes of body structure equally, and successive study about the difference of visceral scheme between iridology and Oriental Medicine would be needed in the future.

• Journal of Veterinary Clinics
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• v.37 no.6
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• pp.345-349
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• 2020

An 8-month-old female rabbit was presented with a white intraocular mass in the right eye. Slit-lamp biomicroscopy showed a white mass behind the iris, accompanied by rubeosis iridis and aqueous flare. Ocular B-scan ultrasonography revealed hyperechoic material within the anterior chamber connected with cataractous lens in the right eye. Signs deteriorated despite treatment, and enucleation was performed. Histopathologically, phacoclastic endophthalmitis due to Encephalitozoon cuniculi infection was confirmed. This was the first report of a client-owned rabbit affected with E. cuniculi-associated phacoclastic uveitis. Serological detection of anti-E. cuniculi antibodies should be considered to prevent potential zoonotic risk.

• Journal of Pharmacopuncture
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• v.12 no.3
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• pp.61-72
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• 2009

Objectives : This experimental study was performed to investigate the safety and efficacy of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. To identify the use of it as eye drop, the eye irritation test of rabbits and the antibacterial test of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, and Candida albicans were performed. Methods : 1. The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration(2005. 10. 21, KFDA 2005-60). After Bovis Calculus pharmacopuncture solution was administered in the left eye of the rabbits, eye irritation of the cornea, iris and conjunctiva was observed at 1, 2, 3, 4 & 7day. 2. After administering Bovis Calculus pharmacopuncture solution on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans) which cause Keratitis, MIC(Minimum Inhibition Concentration) and the size of inhibition zone were measured. Anti-bacterial potency was also measured using the size of inhibition zone. Results : 1. After Bovis Calculus pharmacopuncture solution was administered in the left eye of the rabbits, it was found that none of nine rabbits have abnormal signs and weight changes. 2. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, no eye irritation of the cornea, iris and conjunctiva was observed at 1, 2, 3, 4 & 7day. 3. There was no response to MIC on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans) after Bovis Calculus pharmacopuncture solution was medicated. Conclusions : The present study suggests that Bovis Calculus pharmacopuncture solution is a nontoxic and non-irritant medicine, which does not cause eye irritation in rabbits, but dosen't have antibacterial effects on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans) which cause Keratitis. These study result recommends that more research on other herbal medicines of eye drop for Keratitis are required.