• Korean Journal of Radiology
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• 제22권9호
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• pp.1555-1568
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• 2021

Pulmonary embolism (PE) is a potentially fatal disease if the diagnosis or treatment is delayed. Currently, multidetector computed tomography (MDCT) is considered the standard imaging method for diagnosing PE. Dual-energy CT (DECT) has the advantages of MDCT and can provide functional information for patients with PE. The aim of this review is to present the potential clinical applications of DECT in PE, focusing on the diagnosis and risk stratification of PE.

• 대한임상독성학회지
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• 제9권2호
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• pp.39-48
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• 2011

In mass casualty situation due to radiological accidents, it is important to start aggressive management with rapid triage decisions. External contamination needs immediate decontamination and internal contamination should be treated with special expertise and equipment to prevent the rapid uptake of radionuclides by target organs. Acute radiation syndrome shows a sequence of events that varies with the severity of the exposure. More severe exposures generally lead to more rapid onset of symptoms and severe clinical findings. After the massive exposure, various systems of the body reflect their severe damages that can lead to death within hours or up to several months. The disease progression has classically been divided into four stages: prodromal, latent, manifest illness, and recovery or death. Three characteristic clusters of symptoms including the hematopoietic syndrome, the gastrointestinal syndrome and the cerebrovascular syndrome are all associated with the acute radiation syndrome. The standard medical management of the patients with a potentially survivable radiation exposure includes good medical, surgical and supportive measures. Specific treatment with cytokines and bone marrow transplantation should be considered. The management of internal contamination is much the same as the treatment of poisoning. The standard decontamination should be applied to reduce uptake, and the chelating agents can be administered to enhance the clearance of radioisotopes. Radioactive iodine ($^{131}I$) as one of the nuclear fission products can increase the incidence of thyroid cancer in children. Potential benefit of potassium iodide prophylaxis is greater especially in neonates, infants and small children.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1699-1703
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• 2012

Cervical cancer remains the most frequent cancer in women from the developing world. More than 88% of deaths occur in low-income countries, and it is predicted to climb to 91.5% by 2030. Although Pap-based screening programmes have shown to be effective in reducing the disease burden in high-resource countries, implementation and sustention of cytology-based programmes is quite challenging in low-resource settings. The present paper reviews evidence-based alternatives of screening methods, triaging algorithm, treatment of cervical precancerous lesions, and age-group at screening appropriate for low-income countries. Evidence shows that visual inspection methods using diluted acid acetic or Lugol's iodine, and HPV-DNA testing are more sensitive tests than the Pap-smear screening test. Visual inspection allows an immediate result and, when appropriate, may be immediately followed by cryotherapy, the so called "screen-and-treat" approach, achieved in a single visit, by trained nurses and midwives. Examples of cervical cancer prevention programmes in India and selected low-income countries are given.

• 대한기관식도과학회지
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• 제1권1호
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• pp.151-158
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• 1995

Anaplastic carcinoma of thyroid gland account for no more than 10% of thyroid cancer, but it shows extremely poor prognosis. The purpose of this study is to review the outcome of patients with anaplastic carcinoma over the span of 5 years and to determine the patterns of clinical presentation, age, sex and other possible prognostic variables. We analyzed 30 cases of anaplastic carcinoma retrospectively from 1991 to 1995. There were 14 men and 16 women. There age ranged 33 to 75 years with a mean of 61.0 years. Sixteen patients presented with transformationqr of well differentiated carcinoma to anaplastic carcinoma, 1 with rapid in-crease in the size of long standing goiter, 8 with rapidly growing neck mass and 4 with meta static disease. Twenty-eight patients(93.3%) showed cervical lymphnode metastasis at presentation and twenty three patients(76.6%) showed laryngotracheal invasion. Nine patients (30.3%) showed distant metastasis. Treatment modalities included surgical resection, external irradiation, radioactive iodine and systemic chemotherapy. At decision making of treatment plan, we considered completeness of initial surgery, uptake rate of whole body radioactive io-dine scan, locoregional progression and distant metastasis. The median survival was 6.8 months and three cases survived beyond 12 months.

• 한국환경과학회지
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• 제11권10호
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• pp.1097-1101
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• 2002

Activated carbon is amorphous and its intraparticle pores are well developed. Thus it has high adsorption capabilities and catalytic effect, and is utilized in many areas of industries such as food processing. In recent years, the demand of activated carbon has been increased to solve the environmental problems-waste treatment and removal of poisonous gas. Therefore, in this study an activated carbon was made using the waste and then the industrial characteristics of the produced activated carbon were investigated. The result showed that the carbonization yield was decreased when carbonization temperature was increased from 400 to $600^{\circ}C$ and that the optimal carbonization temperature was $500^{\circ}C$. The optimal concentration of NaOH for removing ash in the raw sample was 1~2N. The iodine adsorption of activated carbon using waste sample at $500^{\circ}C$ carbonization was 1204.28mg/g. The activation result of carbonization sample showed that the optimal activation condition was the carbonization at $500^{\circ}C$ and the activation at $800^{\circ}C$. So the production of activated carbon was thought to be possible, reused as resource, and decreased the environmental pollution.

• 한방안이비인후피부과학회지
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• 제14권2호
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• pp.271-277
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• 2001

Erythema nodosum is a nodular erythematous eruption predominently limited to the pretibial area but occasionally involving the arms or other areas. That is clinical entity defined easily but there are many different opinions about histopathologic findings, Recently erythema nodosum is characterized histopathologically by a septal panniculitis in which the fibrous septa of subcutaneous fat become inflamed. Erythema nodosum has been known to be frequently associated with some kinds of drugs, infections with streptococci, mycobacteria but in $60\%$, no cause is found, Treatment of erythema nodosum consists of supportive care and elimination of underlying causes. Because spontaneous resolution of the lesions can occur in 3 to 6 weeks. Although there are trial treatments are applied to erythema nodosum, ego corticosteroids, NSAIDs, potassium iodine, there isn't any definite. So We report a case of erythema nodosum which was not relieved by NSAIDS but by experimental acupuncture treatment.

• 한국임상수의학회지
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• 제24권3호
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• pp.473-475
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• 2007

A 11-year-old gelding Thoroughbred horse was presented with a history of unilateral nasal discharge of right side. The horse was diagnosed as maxillary sinusitis based on blood examination and radiography. The horse was treated with bone flap of right maxillary sinuses. Abscess of maxillary sinus was drained and irrigated with antibiotic-saline and povidone iodine solution. After surgical procedure, nebulization and medication applied by the result of antibiotic sensitivity test. After treatment for two weeks, the patient was recovered completely.

• 대한두경부종양학회지
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• 제40권1호
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• pp.7-13
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• 2024

The current standard of treatment for differentiated thyroid cancer is surgical resection followed by radioactive iodine therapy according to the recurrence risk. However, external beam radiotherapy may be recommended in limited cases where surgical resection is impossible or residual gross lesion remains or the aforementioned standard therapy is deemed insufficient in achieving local control. We report a case of 59 year old patient who presented with advanced papillary thyroid carcinoma of right neck but was unable to receive surgical resection due to underlying Eisenmenger syndrome. He received radiation therapy of 67.5 Gy in 30 fractions with palliative aim with no further treatment and has been maintaining long-term stable disease state for 38 months. Herein, we report a rare case of palliative aim radiation therapy alone for advanced papillary thyroid carcinoma with literature review.

• 대한수의학회지
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• 제64권2호
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• pp.10.1-10.9
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• 2024

Hyperthyroidism, characterized by elevated thyroid hormone levels and thyroid gland hyperplasia or adenoma, is a prevalent endocrinopathy in older cats. Treatment options include antithyroid drugs, surgical thyroidectomy, and radioiodine therapy (RAIT), which is non-invasive treatment option that can achieve complete remission. However, efficacy and safety of RAIT in hyperthyroid cats have not been investigated in South Korea. This study includes 10 hyperthyroid cats with RAIT. Initial assessments comprised history, physical examination, blood analysis, and serum total T4 (tT4) concentration. Thyroid scintigraphy revealed hyperactivity and enlargement of thyroid gland at 24 hours before the RAIT. Radioiodine (RAI) was injected subcutaneously with 2 to 6 mCi, determined by the fixed dose or the scoring system based on severity of clinical signs, tT4 concentration, and thyroid size individually. After RAIT, the concentration of serum tT4 and liver enzymes were significantly decreased at discharge. However, no significant differences were noted in blood urea nitrogen, creatinine, symmetric dimethylarginine, hematocrits, and white blood cell counts pre- and post-treatment. Although 4 cats received RAI twice, clinical signs disappeared and tT4 levels decreased following the RAIT. All 10 cats achieved complete remission after 6 months without critical adverse effect. The safety and the effectiveness of RAIT was confirmed based on protocols reported other countries. Therefore, RAIT could be considered the treatment option and prevent adverse effects from medication or surgery. This preliminary study presents the first evaluation of RAIT for hyperthyroid cats using locally produced RAI in South Korea and provide valuable insight for clinicians and further studies.

• 대한환경공학회지
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• 제30권6호
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• pp.637-641
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• 2008

이 연구는 과염소산염 제거를 위하여 정수처리장에서 적용 가능한 맞춤분말활성탄 제조와 활성탄 종류에 따른 제거효율 은 비교하기 위하여 수행하였다. Cetyltrimethylammoniumchloride(CTAC)를 이용하여 활성탄에 흡착 전처리하면 과염소산염을 효과적으로 제거 할 수 있었다. 10,000 mg/L 맞춤분활성탄은 농도 5,000 mg/L CTAC 용액 500 mL에 5 g의 분말활성탄을 혼합하여 제조하였다. 맞춤분말활성탄을 이용하면 일반 분말활성탄에 비해 10 이상 높은 과염소산염 제거가 가능하였다. 맞춤 분말활성탄을 이용하여 과염소산염 제거 시 초기 접촉시간 15분은 접촉시간에 따라 잔류 과염소산염의 농도가 줄어들었으나 15분 이후에는 잔류농도의 변화가 거의 없었다. 맞춤분말활성탄 조제 시 활성탄의 요오드가에 따라서 과염소산염 제거능이 달랐는데 요오드가 1,083 mg/g 활성탄은 요오드가 944 mg/g 활성탄에 비해 4배 이상 높은 과염소산염 제거능을 보였다. 일반적으로 정수장에서 주입 가능한 분말활성탄 농도인 5 mg/L 범위의 맞춤분말활성탄 주입농도에서 50 $\mu$g/L의 과염소산염 농도를 15 $\mu$g/L까지 저감 가능하였다.