• 제목/요약/키워드: Invasion area

검색결과 212건 처리시간 0.042초

갑상선 유두상 암종에서 종양혈관형성 및 혈관내피성장인자 발현의 예후인자적 의의 (The Prognostic Significance of Tumor Angiogenesis and Expression of Vascular Endothelial Growth Factor in Papillary Carcinomas of the Thyroid Gland)

  • 강헌대;김성배;김태현;오상훈;윤혜경;김상효
    • 대한두경부종양학회지
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    • 제20권2호
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    • pp.135-142
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    • 2004
  • Objectives: The purpose of this study was to evaluate for prognostic significance of VEGF expression and tumor angiogenesis in papillary carcinomas of the thyroid. Materials and Methods: The materials were 79 cases of papillary thyroid carcinomas, and age, sex, tumor size, multiplicity of tumor, capsular invasion, lymph node metastasis, recurrence, TNM stage, DeGroot stage and AMES scale were evaluated. An immunohistochemical stains for CD 34 to estimate microvessel density (MVD), and VEGF were done. MVD was defined as an average count of vessels per ${\times}400$ power field in the most vascularized area. VEGF expression was interpreted as 1+ and 2+ according to staining intensity and percentages of positive cells. Results: Mean score of MVD was $39.7{\pm}16.9.$ MVD were significantly higher in cases with capsular invasion (p=0.0001), lymph node metastasis (p=0.0001), TNM stage III (p=0.0022), DeGroot stage III (p=0.0163) and high risk group by AMES scale (p=0.0001). VEGF 2+ expression rate was significantly increased in cases with capsular invasion and lymph node metastasis (p=0.0006, p=0.0013), and in cases with TNM stage III, DeGroot stage III and high risk group by AMES scale (p=0.0236, p=0.0003, p=0.0293). In VEGF 2 + expression group, MVD was significantly higher than in VEGF 1 + group (p=0.0008), and MVD showed positive relation to VEGF 2 + expression (r=0.4616). Conclusion: VEGF expression and high MVD were significantly correlated to capsular invasion, lymph node metastasis, TNM stage III, DeGroot stage III and high risk group by AMES scale. The expression of VEGF and high MVD could be considered to be one of prognostic factor in papillary thyroid carcinomas.

스마트폰 기반에서 안전한 디바이스 모니터링을 위한 디바이스 식별 및 통신 기법 설계 (A Design of Device Identification and Communication Method for Secure Device Monitoring based Smart Phone)

  • 진병욱;안희학;전문석
    • 디지털산업정보학회논문지
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    • 제13권1호
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    • pp.69-78
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    • 2017
  • As the smartphone-based devices are diffused and developed rapidly, they provide the convenience to the users. The abovementioned sentence technologies are being used not only in the existing sensor and wireless network technology but also in the application services of the diverse fields application services such as smart appliance, smart car, smart health care, etc. and the new fusion paradigm from the industry is presented by undertaking the researches in diverse area by the enterprises and research institutions. However, the smart environment exposes its weaknesses in the mobile terminal area, existing wireless network and IT security area. In addition, due to new and variant ways of attack, not only the critical information are disclosed However also the financial damages occur. This paper proposed the protocol to perform the smartphone-based safe device monitoring and safe communication. The proposed protocol designed the management procedure of registration, identification, communication protocol and device update management protocol and the safety against the attack techniques such as the an-in-the-middle-attack, impersonation attack, credential threat, information leaks and privacy invasion was analyzed. It was observed that the proposed protocol showed the performance improved by approximately 52% in the communication process than the existing system.

소타액선에 발생된 선양 낭포암 (ADENOID CYSTIC CARCINOMA OF THE MINOR SALIVARY GLANDS)

  • 권경윤;이경호;김동윤;최갑식
    • 치과방사선
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    • 제27권1호
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    • pp.243-249
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    • 1997
  • Adenoid cystic carcinoma is a malignant salivary gland tumor with typical histologic patterns. The majority of these tumors occurs in the minor salivary glands. especially mucosa of the hard palate. The authors experienced the patients, who complained the tumor-like soft tissue masses on the palatal and mouth floor area. After careful analysis of clinical, radiological and histopathological findings, we diagnosed them as adenoid cystic carcinomas in the minor salivary glands, and obtained results were as follows : 1. Main clinical symptoms were a slow growing soft tissue mass with normal intact mucosa on the palatal area, and soft tissue mass with mild pain on the mouth floor area. 2. In the radiographic exarnminations, soft tissue masses were observed with invasion to adjacent structures, and moderate defined, heterogeneous soft tissue mass with enhanced margin, respectively. 3. In the histopathologic exarnminations, dark-stained, small uniform basaloid cells in the hyaline or fibrous stroma were observed as solid and cribriform patterns, respectively.

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프랑스의 신인감독 지원 정책 (Support of CNC for French Young Film Makers)

  • 김이석
    • 한국콘텐츠학회:학술대회논문집
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    • 한국콘텐츠학회 2005년도 춘계 종합학술대회 논문집
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    • pp.208-214
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    • 2005
  • 프랑스는 문화영역에서 강력한 보호정책을 채택하고 있는 국가 중 하나다. '문화적 다양성' 혹은 '문화적 예외'라는 원칙을 내걸고 프랑스는 미국의 '세계화' 정책에 맞서고 있다. 시청각 콘텐츠 영역에서도 마찬가지로 프랑스는 헐리우드 영화의 침범에 맞서 자신의 영화적 영역을 보호하기 위해 보호정책을 채택하고 있다. 프랑스 정부의 다양한 지원 가운데서, 특히 우리는 신인감독에 대한 지원체계와 이 체계 안에서 CNC의 역할에 패해 주목한다. 따라서 이글에서는 정부기관으로서 CNC가 어떻게 프랑스의 시청각영역에 대해 영향력을 행사하는지를 살펴보고, 어떤 과정을 통해 신인감독들의 작업에 실질적인 지원을 제공하는 지를 살펴볼 것이다.

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비무장지대(DMZ) 인근의 훼손지 유형 분석 및 복원방향 (Analysis on the Type of Damaged Land in DeMilitarized Zone(DMZ) Area and Restoration Direction)

  • 성현찬;김수련;강다인;서정영;이상미
    • 한국환경복원기술학회지
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    • 제19권1호
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    • pp.185-193
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    • 2016
  • Purpose of this study is to classify damaged lands according to the cause of the damage and their influences based on characteristic of the damaged lands in DeMilitarized Zone(DMZ) area, and utilize this study as a fundamental study for establishment of ecosystem restoration system. Literature review and field survey have been conducted to review the damage status of DMZ area. For field survey, first year and second year have been conducted, in which type of the damage has been reviewed in this study. In the result, types of damage have been classified into 6 categories: 'alteration of initial landform', 'loss of surface layer', 'land pollution', 'alteration of soil chemical property', 'decline of vegetation', and 'invasion of foreign species'. Restoration for each damage type is as following. First, for alteration of initial landform, the land is restored to the original landform prior to the damage and connection to surrounding ecosystem is considered. Second, for loss of surface layer, lost surface layer is restored or further loss is prevented with stabilization. Third, for land pollution, source of the pollution is eradicated or self-circulation with purification of polluted land is encouraged. Fourth, for alteration of soil chemical property, soil is restored of its original property with eradication of the pollution source and improvement of soil. Fifth, for decline of vegetation, current vegetation and anticipated alteration in future are considered and number of wild species is to be increased based on structure and characteristic of nearby vegetation. Sixth, for invasion of foreign species, prevention of dominance by risky species and facilitation ecological stability with ecological management are to be considered. Influence according to the cause of damage has occurred in secondary(indirect) influence or simultaneous occurrence of several damage types. Considering all these aspects, when type of the damage is complex, restoration process for each of former mentioned 6 damage types with solitary influence should be considered in unison.

인천 승기천의 하안지대에서 지형과 교란에 따른 외래식물의 분포와 식생 구조 (Vegetation Structure and Distribution of Exotic Plants with Geomorphology and Disturbance in the Riparian Zone of Seunggi Stream, Incheon)

  • 신동호;조강현
    • The Korean Journal of Ecology
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    • 제24권5호
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    • pp.273-280
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    • 2001
  • 인천 승기천의 하안지대에서 하천 지형과 교란 요인에 따른 외래식물의 식물상과 식생구조를 조사하였다. 승기천의 전체 하안 회랑에서 총 53종의 외래식물이 발견되었다. 총종수에서 외래식물이 차지하는 백분율은 6개 조사지점에서 25∼33%의 범위이었고, 전체 하안지역에서 평균 24%이었다. 외래식물의 백분율은 교란에 따른 식물 침입에 대한 하안지대의 취약성을 반영하며, 하안 지대에서 생태계 기능의 허약성을 나타내는 지표로서 이용될 수 있었다. 승기천에서 외래식물은 하천의 횡적 구조에서 뚜렷한 분포 유형을 나타내지 않았다. 외래식물의 침입과 증식은 고수부지와 제방사면에서 다소 뚜렷하였다. 여러 교란 요인 중에서 농경과 답압이 외래식물 군집의 침입에 영향을 미치는 중요한 요인이었다.

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이하선으로 직접 전이한 피부 편평상피세포암 (A Case of Direct Invasion of the Parotid Gland by Cutaneous Squamous Cell Carcinoma)

  • 이준호;신혜경;최진수;장태정
    • 대한두개안면성형외과학회지
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    • 제14권2호
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    • pp.129-132
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    • 2013
  • Cutaneous squamous cell carcinoma is the second-most common skin cancer and represents 20% of all skin cancers. Cutaneous squamous cell carcinoma often spreads to the parotid gland through lymph nodes, but, direct invasion of an adjacent organ may also occur. We present the case of 78-year-old man with ulcerated mass on the right infra-auricular area. The histopathologic finding was squamous cell carcinoma. There was no evidence of distant metastasis, but the mass was found to invade the superficial lobe of the right parotid gland. The mass was widely excised and superficial parotidectomy was performed while preserving the facial nerve. The defect was covered by primary closure. Postoperative radiotherapy was performed. At 20 months after surgery, our patient had no facial palsy, local recurrence, or metastasis. Cutaneous squamous cell carcinoma involving the parotid gland is an aggressive, rapidly advancing lesion, which if not recognized and treated early will result in high morbidity and mortality. Squamous cell carcinoma of the parotid gland has shown that patients who receive adjuvant radiotherapy have a lower recurrence rate and a higher survival rate than patients treated with surgery alone. The role of elective neck dissection remains controversial.

인천시 석남동 출토 직물에 관한 연구 (Characteristics of the Excavated Fabrics from unknown Woman's Tomb, Incheon)

  • 조효숙;배순화
    • 복식
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    • 제57권10호
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    • pp.24-34
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    • 2007
  • The purpose of this study is to examine the pieces of 100 fabrics excavated from unknown woman's tomb Incheon, by analyzing woven methods, names of the fabrics, the kinds and the shapes of the patterns. The characteristics to assume the period of the fabrics are as follows. The geumsundan which was woven peacock insignia at chest and back area was excavated for the first time from the tomb of Joseon. Peacock insignia woven with satin weave using supplementary golden wefts, wrapped gold thread. These kind of fabrics were usually imported in the $15^{th}$ century, according to the old documents, 'Nogeoldae' 'Joseonwangjosilrok' written at the end of Goryeo or early in Joseon. Thus, these relics are from about $15^{th}$ century. From this tomb, the mixture fabric of cotton and ramie are excavated. According to another excavated cases, the mixture fabric of cotton and ramie appears from the period before the Japanese Invasion of Korea in 1592, and after the invasion, there are usually mixture fabric of cotton and silk. This also tells that these fabrics show the characteristics of those from the early period of Joseon Dynasty. The rounded patterns of Jangot is only shown from the fabrics of late Goryeo Dynasty, and the cloud pattern of an upper garment with a squared neckline is shown from the early Joseon Dynasty. So, the patterns from these excavated costumes are ranged from the late Goryeo Dynasty to the early Joseon Dynasty. To assume the period through the overall study above, these relics show the characteristics of the $15^{th}$ century fabric.

정보시스템 감리에서 개인정보 영향평가를 통한 개인정보 보호 (Personal Information Protection by Privacy Impact Assessment in Information System Audit)

  • 김희완;유재성;김동수
    • 한국콘텐츠학회논문지
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    • 제11권3호
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    • pp.84-99
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    • 2011
  • 정보 시스템 고도화로 인한 정보의 집적화, 대량화가 점차 확대됨에 따라 개인 정보의 유출 가능성은 날로 높아지고 있다. 이에 따라 개인정보 침해 요소를 사전에 분석하고 최소화 할 수 있는 개인정보 영향평가(PIA)의 필요성이 대두 되고 있다. 그러나, 대부분의 정보시스템 감리에서 시스템 아키텍쳐 영역의 물리적, 관리적, 기술적 보안 항목을 감리하여 일반적인 항목만을 체크하고 있어서 실질적인 개인정보보호를 위한 감리는 제대로 이루어 지지 않고 있다. 이에 따라 본 논문에서는 개인정보 침해를 사전에 최소화하기 위해 개인정보영향을 평가하고 그에 따른 개인정보보호 감리 절차 및 방법을 제시하였다. 본 논문에서 제시한 방법을 프로젝트에 적용한 결과 개인정보 보호를 위한 개선사항이 도출되었음을 확인할 수 있었다.

Role of adjuvant postoperative external beam radiotherapy for well differentiated thyroid cancer

  • Kwon, Jeanny;Wu, Hong-Gyun;Youn, Yeo-Kyu;Lee, Kyu Eun;Kim, Kwang Hyun;Park, Do Joon
    • Radiation Oncology Journal
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    • 제31권3호
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    • pp.162-170
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    • 2013
  • Purpose: To analyze the outcome of adjuvant postoperative external beam radiotherapy (EBRT) in well-differentiated thyroid cancer (WDTC). Materials and Methods: We identified 84 patients treated with EBRT for WDTC from February 1981 to December 2010. Among them, we analyzed 39 patients who received EBRT after initial radical surgery. Twenty-four females and 15 males were included. The median age was 49 years (range, 16 to 72 years). There were 34 papillary thyroid carcinomas and 5 follicular thyroid carcinomas. Most patients showed pathologic T3/T4 stage (54%/26%). Ten patients (25.6%) had gross residual tumors. Five patients (12.8%) had tumor cells at the margin. The median EBRT dose and fraction size were 62.6 Gy and 1.8 to 2.0 Gy, respectively. Results: The median follow-up was 73 months (range, 21 to 372 months). The five-year overall survival (OS) and locoregional recurrence free survival (LRFS) were 97.4% and 86.9%, respectively. Locoregional failures occurred in 5 and all failure sites were the neck node area. In univariate analysis, OS was significantly influenced by invasion of the trachea (p = 0.016) or esophagus (p = 0.006). LRFS was significantly decreased by male (p = 0.020), gross residuum after resection (p = 0.002), close or positive tumor at surgical margin involvement (p = 0.044), and tracheal invasion (p = 0.040). No significant prognostic factor was identified in the multivariate analysis. No patient experienced the Radiation Therapy Oncology Group grade 3 or more toxicity. Conclusion: Our locoregional control rate of 87.2% is comparable to historical controls with surgery alone, even though our study had a large proportion of advanced stage. Adjuvant EBRT may an effective and safe treatment option in patients with WDTC.