• Title/Summary/Keyword: Intraclass Correlation Coefficient

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Reliability of static balance abilities measure using a smartphone's acceleration sensor (스마트폰의 가속도 센서를 이용한 정적균형능력 측정의 신뢰도 연구)

  • Han, Seul-Ki;Lee, In-Hak;Park, Nu-Ri
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.6
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    • pp.233-238
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    • 2016
  • The purpose of this study is to investigate the reliability of static balance measurements using a smartphone. Thirty subjects were selected among university students who had no fractures, history of operation, or inflammatory arthritis, and they had not started regular exercise during the past three months. The smartphone used in this study was a Galaxy S5LTE (SM-G900F, Samsung, Korea, 2014), and the application was a Sensor Kinetics Pro (Ver. 2.1.2, INNOVENTIONS Inc., US, 2015). Static balance ability was measured three times at one-day intervals between tests and retests. The first and second measurements used the same process. Analysis was done using the Wilcoxon signed rank test and intraclass correlation coefficient (ICC (2,1)). The results were as follows. With eyes opened, there was no significant difference (p>0.05), a high volume of correlation (r>0.75, p<0.05), and very high reliability (ICC>0.80) between the first measurement and second measurement. With eyes closed, there was also no significant difference (p>0.05), a high volume of correlation (r>0.75, p<0.05), and very high reliability (ICC>0.80) between the measurements. The results show that the smartphone is likely accurate for measuring static balance. This study will look forward to being the only basis for measuring future application development and the ability to balance.

Psychometric Properties of the Persian Version of Satisfaction with Care EORTC-in-patsat32 Questionnaire among Iranian Cancer Patients

  • Pishkuhi, Mahin Ahmadi;Salmaniyan, Soraya;Nedjat, Saharnaz;Zendedel, Kazem;Lari, Mohsen Asadi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10121-10128
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    • 2015
  • Background: Cancers impose an increasing burden on health of the populations and individuals, but little is known about cancer patient satisfaction with care. The aim of this study was to assess the psychometric properties of the Persian version of European Organisation for Research and Treatment of Cancer (EORTC) In-Patsat32, as a recently developed questionnaire to assess cancer patient satisfaction with care and information provided during hospital admission. Materials and Methods: Complying with EORTC protocols, the Persian version of Inpatsat32 was translated and piloted in a small group of patients, then applied to 380 cancer patients admitted to different oncology wards in Tehran. Validity (convergent, discriminant, and divergent) and reliability of the tool was assessed through using multitrait analysis, factor analysis, intraclass correlations, Chronbach's alpha and test-retest (on a sample of 70 patients). Results: Good acceptance and high sensitivity of the questionnaire with low floor and ceiling effects were recognized, indicating power of the instrument to detect differences between groups with heterogeneous levels of satisfaction. Multitrait scaling analyses supported the convergent validity of the majority of scales (correlation coefficient >0.4) and favorable discriminant validity (item own scale correlation >0.8). There was no correlation between In-patsat32 scales and the EORTC-C30, which measures different concepts, confirming divergent validity of the tool. Internal consistency for all domains was high (${\alpha}$ >0.70) except for the hospital access score and the test-retest reliability was excellent (r=0.86-0.96). There was a weak responsiveness to change except for nurses technical skills. Principle component analysis confirmed five domains with much improved internal consistency (${\alpha}$ >0.9). Conclusions: The Persian version of the EORTC-in-patsat32 module is a reliable and valid instrument to measure cancer patient satisfaction with care received during their hospitalization period and can be utilized in clinical cancer research.

Reliability and Validity of Korean Version of the SWAL-QOL (한국판 SWAL-QOL의 신뢰도와 타당도)

  • Kim, Se-Yun;Cha, Yu-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.5
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    • pp.2981-2988
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    • 2014
  • The Purpose of the this study was to identify reliability and validity of the Korean version of the Swallowing Quality of Life questionnaire(KSWAL-QOL). The study was performed in 71 patients diagnosed dysphagia by videofluoroscopy and 80 healthy swallowers. The reliability was good with a Cronbach's ${\alpha}$ and intraclass correlation coefficient of .86~.96 and .80~.93, respectively. The Pearson product moment correlation coefficients between KSWAL-QOL scales ranged from .17~.74 which was showed significant correlation. Healty swallowers scored higher than dysphagic patients on all scales and statistically significant differences were observed across all the scales between healthy swallowers and dysphagic patients(p<.01). Tube feeders scored lower than non-tube feeders on all scales and statistically significant differences were observed in all the scales except sleep(p<.05). There are significant difference between diet steps in all scales except eating desire, communication, fear and people on diet fourth step feeding had the highest scores on the all scales(p<.05). Because KSWAL-QOL seems to be a reliable and valid tool, it is considered to be appropriate as a tool to measure quality of life of patient with swallowing disorder.

Clinical validation of ImmuneCheck IgE for the rapid detection of serum total IgE (총 IgE의 신속한 정량 측정을 위한 ImmuneCheck IgE의 임상적 유용성)

  • Lee, Shinhaeng;Choi, Jinyoung;Choe, Eunju;Lee, Sang Chul;Park, Kyung Hee;Lee, Jae-Hyun;Park, Jung-Won
    • Allergy, Asthma & Respiratory Disease
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    • v.6 no.6
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    • pp.310-314
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    • 2018
  • Purpose: Conventional serum IgE assay was costly, required the skills of expert, and relied heavily on expensive equipment. Quantitative measurement of total IgE using Point of Care Test (POCT) device can be the solution for these limitations. This study evaluated and validated the reproducibility of ImmuneCheck IgE. Methods: This study included 120 patients of allergic diseases such as allergic rhinitis, asthma, drug allergy, food allergy, atopic dermatitis, or anaphylaxis. The reliability of POCT ImmuneCheck IgE was evaluated by comparing results from the naked eye and from the Q-Reader. Intratest reproducibility and intertest correlation were analyzed using intraclass correlation coefficient (ICC). Results: Of the 120 enrolled patients, 51 were males and 69 were females. The ages ranged from 19 to 84 years, with an average age of 51.5 years. The concentration of serum total IgE measured by Phadia ImmunoCAP IgE ranged from 5.95 to 5,000 IU/mL. ICC for Intratest reproducibility of ImmuneCheck IgE by naked eye and by Q-Reader were 0.991 (P< 0.001) and 0.989 (P< 0.001), respectively. In addition, intertest correlation between ImmuneCheck IgE and Phadia ImmunoCAP IgE results of naked eye and Q-Reader were 0.968 (P< 0.001) and 0.948 (P< 0.001), respectively. Conclusion: The ImmuneCheck IgE was reproducible and highly correlated with conventional Phadia ImmunoCAP IgE assay. This result suggests that ImmuneCheck IgE can be a useful tool for rapid and precise detection of total IgE.

Automated Measurement of Native T1 and Extracellular Volume Fraction in Cardiac Magnetic Resonance Imaging Using a Commercially Available Deep Learning Algorithm

  • Suyon Chang;Kyunghwa Han;Suji Lee;Young Joong Yang;Pan Ki Kim;Byoung Wook Choi;Young Joo Suh
    • Korean Journal of Radiology
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    • v.23 no.12
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    • pp.1251-1259
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    • 2022
  • Objective: T1 mapping provides valuable information regarding cardiomyopathies. Manual drawing is time consuming and prone to subjective errors. Therefore, this study aimed to test a DL algorithm for the automated measurement of native T1 and extracellular volume (ECV) fractions in cardiac magnetic resonance (CMR) imaging with a temporally separated dataset. Materials and Methods: CMR images obtained for 95 participants (mean age ± standard deviation, 54.5 ± 15.2 years), including 36 left ventricular hypertrophy (12 hypertrophic cardiomyopathy, 12 Fabry disease, and 12 amyloidosis), 32 dilated cardiomyopathy, and 27 healthy volunteers, were included. A commercial deep learning (DL) algorithm based on 2D U-net (Myomics-T1 software, version 1.0.0) was used for the automated analysis of T1 maps. Four radiologists, as study readers, performed manual analysis. The reference standard was the consensus result of the manual analysis by two additional expert readers. The segmentation performance of the DL algorithm and the correlation and agreement between the automated measurement and the reference standard were assessed. Interobserver agreement among the four radiologists was analyzed. Results: DL successfully segmented the myocardium in 99.3% of slices in the native T1 map and 89.8% of slices in the post-T1 map with Dice similarity coefficients of 0.86 ± 0.05 and 0.74 ± 0.17, respectively. Native T1 and ECV showed strong correlation and agreement between DL and the reference: for T1, r = 0.967 (95% confidence interval [CI], 0.951-0.978) and bias of 9.5 msec (95% limits of agreement [LOA], -23.6-42.6 msec); for ECV, r = 0.987 (95% CI, 0.980-0.991) and bias of 0.7% (95% LOA, -2.8%-4.2%) on per-subject basis. Agreements between DL and each of the four radiologists were excellent (intraclass correlation coefficient [ICC] of 0.98-0.99 for both native T1 and ECV), comparable to the pairwise agreement between the radiologists (ICC of 0.97-1.00 and 0.99-1.00 for native T1 and ECV, respectively). Conclusion: The DL algorithm allowed automated T1 and ECV measurements comparable to those of radiologists.

The Reliability and Validity of Korean Version of the Interdisciplinary Education Perception Scale(K-IEPS) (한국어판 전문직 간 교육에 대한 인식 측정도구의 신뢰도와 타당도 검증)

  • Park, Hyun Jung;Kang, Hee Sun;Kang, Min Jung
    • Journal of Convergence for Information Technology
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    • v.11 no.12
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    • pp.148-157
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    • 2021
  • This research aims to adapt and evaluate the validity and reliability of the Korean version of the Interdisciplinary Education Perception Scale (K-IEPS). The original IEPS was translated into Korean according to the World Health Organization's guidelines. A total of 302 questionnaires were collected from healthcare professional students at 4 universities in South Korea. The validity and reliability of the scale were measured using Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), Cronbach's alpha, and Intraclass Correlation Coefficient (ICC). As a result of the factor analysis, a ten-item scale with two factors (Competency & Autonomy and Perception of Actual Cooperation) was achieved. Additionally, the Cronbach's alpha coefficient was found to be .87, and test-retest reliability was .83. Our study results show that the Korean version of the IEPS is a valid and reliable instrument. Therefore, the K-IEPS can be used in measuring interdisciplinary perceptions of healthcare professional students between different occupational groups.

CBCT-based assessment of root canal treatment using micro-CT reference images

  • Lamira, Alessando;Mazzi-Chaves, Jardel Francisco;Nicolielo, Laura Ferreira Pinheiro;Leoni, Graziela Bianchi;Silva-Sousa, Alice Correa;Silva-Sousa, Yara Terezinha Correa;Pauwels, Ruben;Buls, Nico;Jacobs, Reinhilde;Sousa-Neto, Manoel Damiao
    • Imaging Science in Dentistry
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    • v.52 no.3
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    • pp.245-258
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    • 2022
  • Purpose: This study compared the root canal anatomy between cone-beam computed tomography (CBCT) and micro-computed tomography (micro-CT) images before and after biomechanical preparation and root canal filling. Materials and Methods: Isthmus-containing mesial roots of mandibular molars(n=14) were scanned by micro-CT and 3 CBCT devices: 3D Accuitomo 170 (ACC), NewTom 5G (N5G) and NewTom VGi evo (NEVO). Two calibrated observers evaluated the images for 2-dimensional quantitative parameters, the presence of debris or root perforation, and filling quality in the root canal and isthmus. The kappa coefficient, analysis of variance, and the Tukey test were used for statistical analyses(α=5%). Results: Substantial intra-observer agreement (κ=0.63) was found between micro-CT and ACC, N5G, and NEVO. Debris detection was difficult using ACC (42.9%), N5G (40.0%), and NEVO (40%), with no agreement between micro-CT and ACC, N5G, and NEVO (0.05<κ<0.12). After biomechanical preparation, 2.4%-4.8% of CBCT images showed root perforation that was absent on micro-CT. The 2D parameters showed satisfactory reproducibility between micro-CT and ACC, N5G, and NEVO (intraclass correlation coefficient: 0.60-0.73). Partially filled isthmuses were observed in 2.9% of the ACC images, 8.8% of the N5G and NEVO images, and 26.5% of the micro-CT images, with no agreement between micro-CT and ACC, and poor agreement between micro-CT and N5G and NEVO. Excellent agreement was found for area, perimeter, and the major and minor diameters, while the roundness measures were satisfactory. Conclusion: CBCT images aided in isthmus detection and classification, but did not allow their classification after biomechanical preparation and root canal filling.

Agreement and Reliability between Clinically Available Software Programs in Measuring Volumes and Normative Percentiles of Segmented Brain Regions

  • Huijin Song;Seun Ah Lee;Sang Won Jo;Suk-Ki Chang;Yunji Lim;Yeong Seo Yoo;Jae Ho Kim;Seung Hong Choi;Chul-Ho Sohn
    • Korean Journal of Radiology
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    • v.23 no.10
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    • pp.959-975
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    • 2022
  • Objective: To investigate the agreement and reliability of estimating the volumes and normative percentiles (N%) of segmented brain regions among NeuroQuant (NQ), DeepBrain (DB), and FreeSurfer (FS) software programs, focusing on the comparison between NQ and DB. Materials and Methods: Three-dimensional T1-weighted images of 145 participants (48 healthy participants, 50 patients with mild cognitive impairment, and 47 patients with Alzheimer's disease) from a single medical center (SMC) dataset and 130 participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset were included in this retrospective study. All images were analyzed with DB, NQ, and FS software to obtain volume estimates and N% of various segmented brain regions. We used Bland-Altman analysis, repeated measures ANOVA, reproducibility coefficient, effect size, and intraclass correlation coefficient (ICC) to evaluate inter-method agreement and reliability. Results: Among the three software programs, the Bland-Altman plot showed a substantial bias, the ICC showed a broad range of reliability (0.004-0.97), and repeated-measures ANOVA revealed significant mean volume differences in all brain regions. Similarly, the volume differences of the three software programs had large effect sizes in most regions (0.73-5.51). The effect size was largest in the pallidum in both datasets and smallest in the thalamus and cerebral white matter in the SMC and ADNI datasets, respectively. N% of NQ and DB showed an unacceptably broad Bland-Altman limit of agreement in all brain regions and a very wide range of ICC values (-0.142-0.844) in most brain regions. Conclusion: NQ and DB showed significant differences in the measured volume and N%, with limited agreement and reliability for most brain regions. Therefore, users should be aware of the lack of interchangeability between these software programs when they are applied in clinical practice.

Comparative Study between ZOOMit and Conventional Intravoxel Incoherent Motion MRI for Assessing Parotid Gland Abnormalities in Patients with Early- or Mid-Stage Sjögren's Syndrome

  • Qing-Qing Zhou;Wei Zhang;Yu-Sheng Yu;Hong-Yan Li;Liang Wei;Xue-Song Li;Zhen-Zhen He;Hong Zhang
    • Korean Journal of Radiology
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    • v.23 no.4
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    • pp.455-465
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    • 2022
  • Objective: To compare the reproducibility and performance of quantitative metrics between ZOOMit and conventional intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) in the diagnosis of early- and mid-stage Sjögren's syndrome (SS). Materials and Methods: Twenty-two patients (mean age ± standard deviation, 52.0 ± 10.8 years; male:female, 2:20) with early- or mid-stage SS and 20 healthy controls (46.9 ± 14.6 years; male:female, 7:13) were prospectively enrolled in our study. ZOOMit IVIM and conventional IVIM MRI were performed simultaneously in all individuals using a 3T scanner. Quantitative IVIM parameters - including tissue diffusivity (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) - inter- and intra-observer reproducibility in measuring these parameters, and their ability to distinguish patients with SS from healthy individuals were assessed and compared between ZOOMit IVIM and conventional IVIM methods, appropriately. MR gland nodular grade (MRG) was also examined. Results: Inter- and intra-observer reproducibility was better with ZOOMit imaging than with conventional IVIM imaging (ZOOMit vs. conventional, intraclass correlation coefficient of 0.897-0.941 vs. 0.667-0.782 for inter-observer reproducibility and 0.891-0.968 vs. 0.814-0.853 for intra-observer reproducibility). Significant differences in ZOOMit f, ZOOMit D*, D*, conventional D*, and MRG between patients with SS and healthy individuals (all p < 0.05) were observed. ZOOMit D* outperformed conventional D* in diagnosing early- and mid-stage SS (area under receiver operating curve, 0.867 and 0.658, respectively; p = 0.002). The combination of ZOOMit D*, MRG, and ZOOMit f as a new diagnostic index for SS, increased diagnostic area under the curve to 0.961, which was higher than that of any single parameter (all p < 0.01). Conclusion: Considering its better reproducibility and performance, ZOOMit IVIM may be preferred over conventional IVIM MRI, and may subsequently improve the ability to diagnose early- and mid-stage SS.

Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20)

  • Jo, Min-Woo;Lee, Hyeon-Jeong;Kim, Soo Young;Kim, Seon-Ha;Chang, Hyejung;Ahn, Jeonghoon;Ock, Minsu
    • Journal of Preventive Medicine and Public Health
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    • v.50 no.1
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    • pp.38-59
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    • 2017
  • Objectives: Few attempts have been made to develop a generic health-related quality of life (HRQoL) instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study. Methods: After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey. Results: Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20), incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality) in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2) were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001). Conclusions: A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.