• 제목/요약/키워드: Intestines

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Differential Cytokine and Immunoglobulin Expressions in the Small Intestine of Echinostoma hortense Infected BALB/c Mice

  • Jo, Yoon-Kyung;Lee, Dong-Sup;Kim, Sung-In;Lee, Ji-Sook;Oh, Ji-Eun;Sung, Ho-Joong
    • 대한의생명과학회지
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    • 제18권3호
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    • pp.254-259
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    • 2012
  • Infections involving Echinostoma hortense (E. hortense) are considered to more severe than infections caused by other heterophyids. Although parasite expulsion by host immune responses attenuates the symptoms of infection, the detailed mechanisms of the host immune response need to be determined, especially in local immune responses involving cytokine and immunoglobulin expressions. We infected BALB/c mice with E. hortense and examined recovery rates together with expressions of multiple cytokines and immunoglobulins in the villi and crypts of the small intestine using immunohistochemistry. We observed a close correlation between worm expulsion rates and cytokine/immunoglobulin expressions in E. hortense infected mice. This study contributes to an understanding of the relationship between the immune response and parasite expulsion in hosts.

결흉(結胸)의 발병 부위에 대한 우재경(尤在涇)의 병리관 (Youzaijing's Pathologic View on the Outbreak Region of Chest Bind)

  • 조원준
    • 동의생리병리학회지
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    • 제22권4호
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    • pp.733-739
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    • 2008
  • It was said that the epigastric region was the outbreak region of chest bind on Shanghanlon. But successive medical men annotated the epigastric region as the chest, which caused the misunderstanding that chest bind was a chest trouble. However Youzaijing, a medical man in Qing dynasty, presented that the epigastric region meant stomach and the middle of stomach did intestines, comparing Dachengqi-tang with Daxianxiong-tang. This view agreed with Huatuo's six-region-transmutation theory. Taojiean and Zhangjingyue also criticized on the six-meridian-transmutation theory, proposing that the change of cold damage didn't go by the fixed rules. This reflected the oriental medical pathologic view that pathogen invaded and advanced to the weak region by the relations between healthy qi and pathogen, and it criticized on the doctrinarian interpretation of Shanghanlon as Neijing. Huatuo insisted that stomach was the final stage of cold damage by presenting that theory. And this theory became a philological basis on Youzaijing's pathologic view.

Primary Myopathic Chronic Intestinal Pseudo-Obstruction in a Maltese Dog

  • Jung, Joohyun;Choi, Mincheol
    • 한국임상수의학회지
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    • 제33권3호
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    • pp.179-182
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    • 2016
  • An 11-year-old castrated male Maltese had vomiting, diarrhea, and abdominal distension for over two weeks and weight loss for several months. Clinical laboratory studies were not remarkable. Abdominal radiographs showed severe dilated intestine with a gravel sign. Colon was empty with normal diameter in the pneumocolon study. On ultrasonographs, most small bowel loops were dilated without normal peristalsis and showed abnormal thin wall. Barium contrast study revealed remarkably delayed gastric emptying and transit time up to $6^{th}$ day. On exploratory laparotomy, there were no mechanical obstruction and extra-intestinal abnormalities except severe dilated small intestine. Chronic fibrosing lymphohistiocytic leiomyositis with atrophy of tunica muscularis in the small intestines and colon was identified through full thickness biopsy and histopathology. Therefore, primary myopathic chronic intestinal pseudo-obstruction was diagnosed. This dog is survival with symptomatic treatments for eight months.

성인에서 발생한 Bochdalek Hernia 수술치험 1예 (A case of bochadalek hernia in adult)

  • 권우석
    • Journal of Chest Surgery
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    • 제19권2호
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    • pp.331-334
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    • 1986
  • Bochdalek hernia in adult is relatively uncommon. We experienced a surgical case of Bochdalek hernia in a 29 year old housewife. She was admitted via E-R due to left chest pain and nausea for 1 months. 5 days before admission, she had Cesarean section on private hospital. After delivery, nausea and exertional dyspnea were aggravated. On admission, chest PA showed herniated stomach, colon, small intestine on left thorax. She was diagnosed of diaphragmatic hernia and operated. Operative findings were as follows: 1. hypoplastic: lower lobe of left lung, 2. stomach, colon, small intestine, spleen were herniated, 3. the defect was located on posterolateral portion of diaphragm, measuring 10 x 8 cm in size. Herniated intestines were reduced and diaphragmatic defect was repaired as interrupted sutures with 2-0 Mersilene. Postoperative courses were uneventful and the patient was discharged on POD 10th.

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Effect of Soy Protein Diet on Mucosa Layer of Murine Small Intestine

  • Lee, Aeri;Lim, Jinkyu
    • Current Research on Agriculture and Life Sciences
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    • 제32권1호
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    • pp.34-42
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    • 2014
  • Soy and fermented soy are popular and recognized as a health food among Koreans. Since soy proteins are known to be protease resistant, even to pepsin and pancreatin, it is hypothesized that soy proteins may interact with the intestinal tract and trigger certain physiological reactions. To test this hypothesis, mice were fed diets supplemented with soy, Chunkukjang, or casein. The differentially expressed proteins were analyzed using 2-D gels and identified by peptide mass fingerprinting using mass spectrometry. The majority of the differentially expressed proteins could be functionally grouped into metabolic enzymes and calcium-binding proteins. The differential protein expression by the soy-fed groups was also verified based on a representative protein, tropomyosin, using a Western blotting analysis. In addition, the soy-fed groups exhibited a taller villi structure. Therefore, this study suggests that soy proteins can be an effective nutrient and physiological stimulant for the intestines.

Production of Transgenic Mice Secreting a C. thermocellum Cellulase D in the Pancreas

  • Park, Jung-Ok;Lee, Eun-Ju;Kim, Myoung-Ok;Kim, Sung-Hyun;Park, Jun-Hong;Cho, Kyung-In;Nam, Myung-Su;Park, Hum-Dai;Ryoo, Zae-Young
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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    • pp.94-94
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    • 2002
  • Increasing competition in the livestock industry has forced producers to cut costs by adopting new technologies aimed out increasing production efficiency. Non-ruminant livestock do not express fibrolytic enzymes. The major plant cell wall components of cereals, primarily β-glucans and arabinoxylans, form gel-like structures in the small intestines that trap nutrients. The viscous polysaccharides can also cause severe gastrointestinal disorders. (omitted)

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Purine Derivatives Excreted in Urine as an Indicator Estimating Microbial Yield from the Rumen: A - Review

  • Kanjanapruthipong, J.;Len, R.A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제11권3호
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    • pp.209-216
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    • 1998
  • The paper presented here is aimed at increasing knowledge on purine metabolism in ruminants and hence the quantification of microbial cells entering the small intestine from urinaη excretion of purine derivatives. Nucleic acid metabolisms of micro-organisms in the rumen, digestion and absorption of nucleic acids entering the intestines, metabolisms of absorbed and endogenous purines involving de novo synthesis of nucleic acids in the ruminants host, and the relationship between absorbed and excreted purines are reviewed. Principal concerns about an amount of purine derivatives excreted in urine in relation to a change in purine-N: total-N ratios in rumen microbes that leave the rumen are discussed. The use of urinary excretion of purine derivatives as an indicator of the amount of microbial biomass leaving the rumen has to be done with some caution since it may be impossible to get a representative sample of microbes entering the intestine and thus yield estimates are relative rather than absolute.

Production of c9,t11- and t10,c12-conjugated Linoleic Acids in Humans by Lactobacillus rhamnosus PL60

  • Lee, Ki-Eun;Lee, Yeon-Hee
    • Journal of Microbiology and Biotechnology
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    • 제19권12호
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    • pp.1617-1619
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    • 2009
  • Lactobacillus rhamnosus PL60 was tested for whether it can produce c9,t11- and t10,c12-conjugated linoleic acids (CLAs) in human. After consumption of L. rhamnosus PL60, L. rhamnosus was detected in feces 1 week after the start of intake. Analysis by gas chromatography showed that concentrations of c9,t11- and t10,c12-CLAs in serum had increased and concentrations of serum leptin had significantly decreased. Results showed that L. rhamnosus PL60 can survive in human intestines and produce CLAs in humans. This is the first report that bacteria can produce CLAs in humans.

삼초유형(三焦有形)으로 살펴본 삼초(三焦)의 기능(機能), 병증(病證) 및 장부배합(臟腑配合) (Function Disease Symptom And Organ Coordination of Tri-Energizer Based on the Materiality of Tri-Energizer)

  • 윤창열
    • 대한한의학원전학회지
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    • 제26권2호
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    • pp.1-7
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    • 2013
  • Objective & Method : By investigating physiological function of tri-energizer, symptoms, and organ coordination, we obtained following conclusion. Tri-energizer is the membrane structure that surrounds the five visceral organs and six hollow organs, and filled with fluid. Tri-energizer acts as the passage for the flow of qi energy. Result & Conclusion : Therefore, dysfunction of the tri-energizer is caused by abnormal evaporation and metabolism. Upper-energizer regulates cardiopulmonary function, middle-energizer regulates spleen and stomach functions, and lower-energizer regulates liver, kidneys, small and large intestines, and bladder functions. Such a functional specialization is possible by receiving the source of qi through the wall wrapping around the internal organs. Tri-energizer represents the exterior and interior relationship by acting as the membrane structure supporting the five visceral organs and six hollow organs and at the same time, as the pericardium surrounding the heart.

Isolation, Identification, and Culture Conditions of the Strain Producing Eicosapentaenoic Acid

  • Shin, Won-Cheol;Kim, Chang-Ho
    • Journal of Microbiology and Biotechnology
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    • 제4권4호
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    • pp.338-342
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    • 1994
  • The bacterium producing EPA was isolated from the intestines of the marine fishes. The strains were studied for their identification and their culture conditions. The selected strain was gram negative, rod(0.7 $\times$ 2.4 $\mu m$ in size) and motile with a single polar flagellum. This strain was identified as a Pseudomonas sp. on the basis of its morphological, cultural and physiological characteristics. The strain showed a maximum productivity of phospholipid at $20^{\circ}C$ after 48 hours of culture time with an initia1 pH of 7.0 in the PYM-glucose medium. Under these culture conditions, the production of phospholipid was about 0.3 mg/ml and 0.06 mg/mg dry cell weight.

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