• Title/Summary/Keyword: Interstitial

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Abattoir survey of kidney lesions in Korean cattle (도축한우의 신장에 대한 병리학적 연구)

  • 노영선;윤여백;김영진;이성희;레브코로지스키;임병무;임채웅
    • Korean Journal of Veterinary Service
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    • v.24 no.2
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    • pp.139-146
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    • 2001
  • To examine the prevalence and types of kidney lesions in Korean cattle, a survey was carried out at a abattoir in september 2000 and January 2001. The collected kidneys were examined grossly and histopathologically and investigated for the patterns of renal diseases with considering season and sex. Of 735 cattle (99 bulls and 246 cows in September and 140 bulls, 3 steers, and 247 cows in January) surveyed, 301 (41%) cattle had various renal lesions. The most common prominent finding was focal or multiple interstitial nephritis (36.2%). Other lesions included focal or multiple renal cyst (9.1%), infarction (0.1%), hemorrhage (0.3%), and renal atrophy (0.3%). Microscopically, main pathological lesions were acute or chronic interstitial nephritis with moderate infiltration of neutrophil or lymphocyte, respectively. Finally, the kidney lesions are more or less correlated with the meat quality, especially in female Korean cattle.

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Chromosome Identification of Durum Wheat by Acetocarmine Wright C-banding Technicque. (C-banding 법에 의한 Macaroni Wheat 의 염색체동정)

  • 오세관
    • Korean Journal of Plant Resources
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    • v.4 no.1
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    • pp.5-12
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    • 1991
  • A combination of acerocarininc-Wright C-banding technique was utilized to identify each chromosomes in durum wheat ,Triticum durum var. Hordeiforme (2n=4x=28 AABB), This technique elucidated qualitativr and quantitative traits of the indi-vidual chromosomes In coinplement. Most comspicuous bands were observed at thecentromere of B-genome chronmosomes. Each chromosomes of A-genome had some-what weak centromeric, proximal and terminal bands. Chromosomes 2A and 4A hasa small subterminal bands. 6A is smallest and metacentric chromosome and , has two faint interstitial band. Chromosomes 1B and 6B showed satellite and constriction lage band. Short arm of 3B has three heavily interstitial bands. Both arms of chromosome 4B has a lagc centromeric band and a very lage proximal band. 5B had heavilycentromeric band and the long arm showed prominent two interstitial bands. Chromo-somes 25 and 7B has a small terminal band of both arms.

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The Study of Standardization of Temperature Distribution of Interstitial Hyperthermia -In Phantoms and Living cat's brain tissue (Normal Tissue)- (915 MHz 극초단파 자입온열시 온도분포 적정화에 관한 연구 -조직등가물 및 가묘대뇌를 대상으로-)

  • Kyoung Hwan Koh;Cho Chul Koo;Park Young Hwan;Yoo Seong Yul;Kim Jong Hyun;Lee Seung Hoon
    • Radiation Oncology Journal
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    • v.8 no.1
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    • pp.7-15
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    • 1990
  • The ultimate objective of our experiment is to obtain the precise distribution of temperature in malignant tumors occurring in cerebral parenchyme of human beings when we will carry out interstitial hyperthermia in the near future. To achieve this purpose, first of all, it is necessary to make an attempt at performing interstitial hyperthermia in vivo under the similar condition of human beings. Therefore, we chose cats as materials much alike tissue characteristics of human beings. Moreover, it is also necessary to get the basic data from dynamic phantom in order to standardize and compare results obtained from interstitial hyperthermia carried out in cats. By having performed these experiments we got the following results. 1) On doing interstitial hyperthermia with 915 MHz microwave, the possible treated volume was 2 cm by 2 cm by 6 cm according to $50\%$ specific absorption rate (SAR). 2) The distribution of temperature within non-circulated static phantom was much the same as power density in air, but we observed that the temperature, within $5\~10$ minutes, rose to more higher than $55^{\circ}C$ not measured with Ga-As fiberoptic thermistor which was not impeded by microwave after performing interstitial hyperthermia. 3) Within dynamic phantom in which normal saline was circulating, temperature reached steady state which was maintained for more than 45 minutes through transit period in 5 minutes after starting interstitial hyperthermia. 4) When we interrupted circulation in the dynamic phantom, we observed that temperature rose to the same level as in the static phantom. 5) We could carry out interstitial hyperthermia safely when we used the generating power below 5 watts. Abrupt interruption of circulation caused a rapid increase in temperature. Times taking to rise to maximum $55^{\circ}C$ were 15.2 minutes (SE 0.4),9.7 minutes (SE 0.3), and 6.3 min-utes (SE 0.4) respectively with generating powers of 5,10, and 15 watts.

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A Case of Idiopathic Interstitial Pneumonia in Childhood (소아 특발성 간질성 폐렴 1례)

  • Lee, Su-Jin;Shin, Eon-Woo;Park, Eun-Young;Oh, Phil-Soo;Lee, Kon-Hee;Kim, Kwang-Nam;Shin, Ho-Seung;Lee, Il-Seung
    • Clinical and Experimental Pediatrics
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    • v.48 no.3
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    • pp.327-332
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    • 2005
  • Interstitial lung disease refers to a group of pulmonary disorders characterized by inflammation of the interstitium, derangements and loss of alveolar capillary units leading to disruption of alveolar gas exchange, which induces symptoms of restrictive lung disease. Cases of interstitial pneumonia in children are uncommon and mostly have unknown causes. We have experienced an 8-year old boy who had symptoms of cyanosis, dry cough, dyspnea and abrupt weight loss. He had not been exposed to organic dusts, allergens or any other systemic disease infections. Chest radiology showed diffuse ground glass opacity in both lung fields. High resolution computed tomography(HRCT) showed multiple small patchy areas of consolidation with an underlying ground glass appearance in both lungs. The pathologic findings of lung biopsy tissue showed patchy areas of interstitial fibrosis, alveolar obliteration and nodular fibrotic areas, strongly suggesting interstitial pneumonia. No specific finding of viral inclusion or any other evidence of infection was found under electromicroscopy. We used peak flow meters to compare functional improvement. Forced expiratory volume in one second ($FEV_1$) was decreased to 25 percent of predicted value. The boy was given treatment with prednisone and showed improvements in HRCT findings after two months. He was able to tolerate easy exercise in school and showed clinical improvements after one year of follow up.

A Case of Respiratory Bronchiolitis-Associated Interstitial Lung Disease (호흡성 세기관지염-연관 간질성 폐질환 1예)

  • Ahn, Byeong-Hoon;Park, Hyung-Suk;Do, Jung-Ho;Suh, Gee-Young;Chung, Man-Pyo;Rhee, Chong-H.;Kim, Kwan-Min;Lee, Kyung-Soo;Han, Jung-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.1
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    • pp.103-109
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    • 1999
  • Respiratory bronchiolitis-associated interstitial lung disease has been described among current or former smokers and has features consistent with interstitial lung disease. Symptoms include cough, dyspnea on exertion. Lung pathology is characterized by the accumulation of pigmented macrophages within respiratory bronchioles and adjacent air spaces associated with mild thickening of the peribronchiolar interstitium. It must be separated from the other interstitial lung disease because of marked differences in treatment and prognosis. Recently we experienced a case of respiratory bronchiolitis-associated interstitial lung disease in a 48-year-old man. As far as we know, this is the first case in Korea.

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Structural and Histochemical Changes in the Cyst cell and the Interstitial Cell in the Testis of a Teleost Hexagrammos agrammus associated with the Reproductive Cycle (생식주기(生殖周期)에 따른 노래미, Hexagrammos agrammus 정소내(精巢內)의 cyst 세포(細胞) 및 간질세포(間質細胞)의 구조적(構造的), 조직화학적(組織化學的) 변화(變化))

  • Chung, Ee-Yung;Lee, Ki-Young
    • Korean Journal of Ichthyology
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    • v.6 no.2
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    • pp.193-205
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    • 1994
  • In order to understand fine structural and histochemical changes in the cyst cell and he interstitial cell in the testis of the spottybelly greenling Hexagrammos agrammus associated with the reproductive cycle from January to December, 1992, there cells were studied by electron microscopy and light microscopy. The cyst cells in the mature testis show a weak affinity to haematoxylin. while they become larger in size. At this time, these cells appear to be more functional than those on the growing stage because several mitochondria, endoplasmic reticulum, glycogen particles and a few lipid droplets appear in the cytoplasm of the cyst cell. It appears, therefore, that the cyst cell of this species has vital functions for nutrition, secretion and steroidogenesis. Well-developed interstitial cells contain large rod-shape or spherical mitochondria with tubular cristae and the large quantities of smooth endoplasmic recticulum and electron-dense materials in the vesicle at the mature and spawning stage. The interstitial cells of this species show characteristics of steroid interstitial cells having a vesicular nucleus, mitochondria with tubular cristae, and smooth endoplasmic reticulum. However, these interstitial cells of teleost give negative histochemical reactions for Sudan black B.

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Interstitial Lung Disease Associated with Polymyositis: Response to Cyclophosphamide and Prednisolone Combination Treatment (Cyclophosphamide와 Prednisolone 병합요법에 치료반응을 보인 다발성근염에 동반된 간질성폐질환 1예)

  • Moon, Jong-Ho;Park, Jun-Young;Lee, Sang-Moo;Kim, Hyeon-Tae;Uh, Soo-Taek;Chung, Yeon-Tae;Kim, Yong-Hoon;Park, Choon-Sik;Lee, Kyung-Soo;Kang, Dae-Young
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.2
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    • pp.197-202
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    • 1993
  • Polymyositis (PM) is a inflammatory connective tissue disease involving predominantly skeletal muscles, characterized by symmetrical, proximal muscle weakness, inflammation, and frequently, degeneration. Interstitial lung disease in association with PM occurs in 5~10% of cases and carries an especially grave prognosis. Although the cause of lung involvement in PM is not known, the underlying pathologic process in the lung is an immune mediated inflammation of alveolar structures, alveolitis. It is of interest, therefore, that cyclophosphamide, an immune modulating agent, has been reported to be effective in the treatment of PM. We report a case of corticosteroid resistant PM associated with interstitial lung disease, successfully treated with cyclophosphamide. A 37-year-old female was presented with 8 months duration of cough, exertional dyspnea, and muscle weakness. She had typical symptoms, physical findings, and elevated muscle enzyme levels in serum with characteristic findings of muscle biopsy. She also had typical interstitial lung disease pattern on chest X-ray and high resolution CT with restrictive pattern on pulmonary function test. The findings of transbronchial lung biopsy was compatible with interstitial lung disease. She failed to respond to corticosteroid initially. Subsequently steroids and cyclophosphamide were given with excellent clinical improvement.

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Interstitial Pneumonia and Lung Cancer Surgery (간질성 폐렴과 폐암수술)

  • Sa Young-Jo;Wang Young-Pil;Park Jae-Kil
    • Journal of Chest Surgery
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    • v.39 no.4 s.261
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    • pp.304-309
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    • 2006
  • Background: Interstitial pneumonia is associated with an increased risk of lung cancer but the outcome of surgical resection in this setting is unknown. The purpose of this study was to determine the relationship between pre-operative interstitial pneumonia (IP) and post-operative respiratory failure. Material and Method: A retrospective review of 672 patients with lung cancer who underwent curative pulmonary resection at the Hospital of Catholic University Medical College between 1997 and 2005 was undertaken. The patients were divided into two groups according to preexisting interstitial pneumonia and not by the pre-operative chest HRCT or findings of pathologic papers. The pre-operative data and cancer-related findings were analyzed between the IP group and non-IP group, and between the respiratory failure group and non-failure group in IP patients. Result: Twenty-eight patients (4.2%) of the developed post-operative respiratory failure and this proved to be fatal in 21 of these patients. We could find preoperative interstitial pathology in 53 patients (7.9%) among the 672 patients. The incidences of respiratory failure were 11.3% (6/53 cases) and 3.6% (22/619 cases) in IP group and non-IP group respectively, Conclusion: Interstitial pneumonia was considered one of the risk factors for developing postoperative acute respiratory failure in patients with lung cancer.

Content-Based Image Retrieval of Chest CT with Convolutional Neural Network for Diffuse Interstitial Lung Disease: Performance Assessment in Three Major Idiopathic Interstitial Pneumonias

  • Hye Jeon Hwang;Joon Beom Seo;Sang Min Lee;Eun Young Kim;Beomhee Park;Hyun-Jin Bae;Namkug Kim
    • Korean Journal of Radiology
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    • v.22 no.2
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    • pp.281-290
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    • 2021
  • Objective: To assess the performance of content-based image retrieval (CBIR) of chest CT for diffuse interstitial lung disease (DILD). Materials and Methods: The database was comprised by 246 pairs of chest CTs (initial and follow-up CTs within two years) from 246 patients with usual interstitial pneumonia (UIP, n = 100), nonspecific interstitial pneumonia (NSIP, n = 101), and cryptogenic organic pneumonia (COP, n = 45). Sixty cases (30-UIP, 20-NSIP, and 10-COP) were selected as the queries. The CBIR retrieved five similar CTs as a query from the database by comparing six image patterns (honeycombing, reticular opacity, emphysema, ground-glass opacity, consolidation and normal lung) of DILD, which were automatically quantified and classified by a convolutional neural network. We assessed the rates of retrieving the same pairs of query CTs, and the number of CTs with the same disease class as query CTs in top 1-5 retrievals. Chest radiologists evaluated the similarity between retrieved CTs and queries using a 5-scale grading system (5-almost identical; 4-same disease; 3-likelihood of same disease is half; 2-likely different; and 1-different disease). Results: The rate of retrieving the same pairs of query CTs in top 1 retrieval was 61.7% (37/60) and in top 1-5 retrievals was 81.7% (49/60). The CBIR retrieved the same pairs of query CTs more in UIP compared to NSIP and COP (p = 0.008 and 0.002). On average, it retrieved 4.17 of five similar CTs from the same disease class. Radiologists rated 71.3% to 73.0% of the retrieved CTs with a similarity score of 4 or 5. Conclusion: The proposed CBIR system showed good performance for retrieving chest CTs showing similar patterns for DILD.

Temperature Variations in the Sediments and the Concentration of Nutrients in Interstitial Water at the Tidal Flats (간석지 개흙속의 온도변화와 간극수내의 영양염농도 분포특성)

  • Park Jong-hwa
    • KCID journal
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    • v.5 no.2
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    • pp.41-51
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    • 1998
  • Spatial distributional patterns of temperature in the sediments and the concentration of nutrients in interstitial water were particular interests on the ecological research of tidal flats. It was the aim of this paper to grasp inhabiting environment of t

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