• International Journal of Oral Biology
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• v.32 no.1
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• pp.1-5
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• 2007

Receptor activator of nuclear factor ${\kappa}B$ ligand (RANKL) induces osteoclast formation from hematopoietic cells via up-regulation of positive regulators, including $NF-{\kappa}B$, c-Fos, microphthalmia transcription factor (Mitf), PU.1, and nuclear factor of activated T cells (NFAT) c1. In addition to the positive regulation by these transcription factors, RANKL appears to regulate negative regulators such as MafB and inhibitors of differentiation (Ids). Ids and MafB are abundantly expressed in osteoclast precursors, bone marrowderived monocyte/macrophage lineage cells (BMMs). Expression levels of these genes are significantly reduced by RANKL during osteoclastogenesis. Overexpression of these genes in BMMs inhibits the formation of tartarate-resistant acid phosphatase (TRAP)-positive multinuclear osteoclasts by down-regulation of NFATc1 and osteoclast-associated receptor (OSCAR), which are important for osteoclast differentiation. Furthermore, reduced expression of these genes enhances osteoclastogenesis and increases expression of NFATc1 and OSCAR. Taken together, RANKL induces osteoclastogenesis via up-regulation of positive regulators as well as down-regulation of negative regulators.

• International Area Studies Review
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• v.18 no.3
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• pp.249-265
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• 2014

The international mobile roaming service has been provided for more than one decade, but high price of international mobile roaming service, which is represented as 'bill shock' is still of major concern in lots of countries including Korea. With understanding of the given price issues, the international organizations, such as OECD, EU, WTO, ITU have been conducting extensive analyses and studies to find suitable solutions and appropriate measures. In the case of EU regulate the international roaming charges and implement the regulation policy. OECD do not have a compelling regulation on roaming charges, but OECD request to member state to find the reasons of high roaming charges and its solution. WTO Council for Trade in Services is reviewing the international mobile roaming in terms of whether impede international trade in services. The purpose of this study is to review many different approaches in international organizations related to reducing international roaming service charges, to drive some regulatory policy directions for reducing roaming charges.

• Korea Trade Review
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• v.44 no.6
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• pp.201-216
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• 2019

At present, there are various standards used as the governing law of contracts for establishing, implementing, and resolving disputes between the parties to international sales contracts, called "Forum Shopping." Uncertainty and increased transaction costs, which may arise from these various norms, may hinder the activation of international commerce. This study examines the process of enacting and examining various international unification norms that have emerged through international organizations to eliminate trade barriers caused by choice of governing law concerning parties involved in the international sale of goods. Issues regarding the positive and negative perspectives are discussed to identify obstacles to international unification norms. In particular, by comparing and analyzing the differences between the regulations of the CISG and PICC, the representative international unification norms on international sales contracts, the possibility of unification of the norms on international sales contracts are reviewed. Direction for the establishment of a single international regulation is presented for reducing the transaction costs and uncertainties in the international sale of goods.

• Journal of Fisheries and Marine Sciences Education
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• v.29 no.2
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• pp.365-379
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• 2017

The purpose of this study was to test the mediated effects of emotional regulation in the relations between maternal parenting and children's adaptation to school life of elementary school students. Three-hundred Seven elementary school students completed the maternal parenting scale, the emotional regulation scale, and the adaptation to school life scale. In order to find to identify how maternal parenting, emotional regulation were related with their adaptation to school life, Pearson correlation coefficients were used in the computation. To examine the effects of maternal parenting, emotional regulation on adaptation to school life, multiple regression analyses were conducted. To examine whether emotional regulation as a mediating variable in the process that maternal parenting is influencing children's adaptation to school life, hierarchical regression analyses were performed. The results of this study were summarized as follows. First, the analysis of the relationship of maternal parenting, emotional regulation with adaptation to school life shows that there is a significant positive correlation between maternal parenting, emotional regulation and adaptation to school life. Second, in the multiple regression analysis with maternal parenting and emotional regulation as a predictor and adaptation to school life as an outcome variable it has been shown that the emotional regulation were significant in adaptation to school life, but maternal parenting were not significant in adaptation to school life. The higher the emotional regulation is the better can children adapt themselves to school life. Third, the analysis on the mediating effects of emotional regulation in the relationship of maternal parenting and adaptation to school life showed that emotional regulation full mediates the relationship of maternal parenting with adaptation to school life.

• International Commerce and Information Review
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• v.19 no.2
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• pp.3-24
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• 2017

The level of ICT in the country affects economic performance as a basic infrastructure that has a significant impact on the competitiveness of the country. With the proliferation of globalization, ICT-related economic activities such as electronic trade are becoming more active, and the importance of ICT in the country is increasing. This study sought to analyze the impact of ICT level on the economic performance of the nation by subdividing it into three dimensions: accessibility, usage, and utilization skill. In particular, we sought to find ways to effectively resolve the digital divide between developed and developing countries by analyzing the difference in economic impact of ICT level. Furthermore, we tried to verify whether the government regulation and firm's nature of competitive advantage in the international markets play a moderating role in the economic impacts of ICT in the country. As a result of panel analysis with data collected from ITU, WEF and World bank national ICT level has consistently significant influence on economic growth in terms of access and usage. In addition, it was confirmed that the competitive advantage of companies in developed countries and the government regulation in developing countries have a significant moderating effect on the relationship between ICT level and economic growth.

• Proceedings of the Korean Nuclear Society Conference
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• 2003.05a
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• pp.450.1-450.1
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• 2003

• International Journal of Stem Cells
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• v.17 no.2
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• pp.99-101
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• 2024

• Special Issue of the Society of Naval Architects of Korea
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• 2007.09a
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• pp.14-21
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• 2007

A passenger ship is consist of five(5) constituents; passenger, sea, crew, port and ship itself and the rule & regulation which is applicable to passenger ship are differently required as their objects of constituents. the basic concept of rule & regulation can be defined all activities to keep safety of ship and her constituents. Especially, the rule & regulation for passenger ship design and construction shall be considered not only safety of ship itself but also safety of lives, so its are required more severe than commercial vessel. Recently, the IMO have finished the rule making work on the 'passenger ship safety' since it has been discussed last 2000 and next MSC meeting will be adopted the results. In this paper, the application method of rule & regulation are treated and the new rule which were made by IMO are introduced. The rule & regulation for passenger ship is one of the most important things. therefore, it is required to careful consideration to apply on the rule application.

• Educational Technology International
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• v.20 no.2
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• pp.223-255
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• 2019

The purpose of this study is to draw implications for designing online tools to support monitoring in collaborative learning. For this purpose, eighteen research papers that explored learner dashboards and group awareness tools were analyzed. The driving questions for this analysis related to the information and outcomes that must be monitored, whose performance they represent, and who monitors the extent of learning. The analytical frameworks used for this study included the following: three modes of co-regulation in terms of who regulates whose learning (self-regulation in collaborative learning, other regulation, and socially shared regulation) and four categories of dashboard information to determine which information is monitored (information about preparation, participation, interaction, and achievements). As a result, five design implications for learner dashboards that support monitoring were posited: a) Monitoring tools for collaborative learning should support multiple targets: the individual learner, peers, and the entire group; b) When supporting personal monitoring, information about the individual and peers should be displayed simultaneously to allow direct comparison; c) Information on collaborative learning achievements should be provided in terms of the content of knowledge acquired rather than test scores; d) In addition to information related to interaction between learners, the interaction between learners and learning materials can also be provided; and e) Presentation of the same information to individuals or groups should be variable.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.53
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• pp.265-288
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• 2012

Trade in service, which deals with intangible product, is distinguished from trade of goods for tangible product. The current multilateral service trade is based on GATS which includes MFN, securing the predictability as well as transparency of related service rules, specific commitment basis market access national treatment. Recently the WTO service disputes are increasing according to the frequent filing complaints against the regulation of service trade in China. The rules of GATS are not as strict as those of GATT. The commitment schedules, which were materialized between members, gets binding effect through the obligatory provisions of GATS. The GATS is inseparable relation with the Appendix of finance, of telecommunication, and of air transport, with the schedules of commitment of member states, and with the reference paper to the 4th protocol. GATS article XIV which is the general exception of GATS has a similar structure of GATT article XX. Based on the possibility of filing to the WTO, there is a need to examine whether the whole rules, regulation, and policy international trade in service of Korea perfectly macthed with the GATS. Korea with poor resources should take up the more positive attitude for the opening of international service market. According to the reciprocal aspects of concession, if Korea doesn't open a service market, the other WTO member country wouldn't allow Korea to access the their market as well as national treatment.