• BMB Reports
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• v.54 no.5
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• pp.253-259
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• 2021

Aging is characterized by a functional decline in most physiological processes, including alterations in cellular metabolism and defense mechanisms. Increasing evidence suggests that caloric restriction extends longevity and retards age-related diseases at least in part by reducing metabolic rate and oxidative stress in a variety of species, including yeast, worms, flies, and mice. Moreover, recent studies in invertebrates - worms and flies, highlight the intricate interrelation between reproductive longevity and somatic aging (known as disposable soma theory of aging), which appears to be conserved in vertebrates. This review is specifically focused on how the reproductive system modulates somatic aging and vice versa in genetic model systems. Since many signaling pathways governing the aging process are evolutionarily conserved, similar mechanisms may be involved in controlling soma and reproductive aging in vertebrates.

• Structural Engineering and Mechanics
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• v.82 no.2
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• pp.259-270
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• 2022

The paper investigates the residual stresses arising in a thermoviscoelastic cylinder as a result of layer-by-layer deposition of material on its lateral surface. Internal stresses are caused by incompatible deformations that accumulate in the assembly as a result of joining parts with different temperatures. For the analysis of internal stresses, an analytical solution to the axisymmetric quasi-static problem of thermoelasticity for a growing cylinder is constructed. It is shown that the distribution of residual stresses depends on the scenario of the surfacing process. In this case, the supply of additional heat to the growing body can significantly reduce the unevenness of temperature fields and reduce the intensity of residual stresses. The most effective is uneven heating, which can be realized, by the action of an alternating current with a tunable excitation frequency. The temperature and residual stresses fields on the growing surface is analyzed numerically for Titanium and Copper materials.

• BMB Reports
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• v.56 no.4
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• pp.209-215
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• 2023

Maintaining internal homeostasis and regulating innate behaviors are essential for animal survival. In various animal species, a highly conserved neuroendocrine system integrates sensory inputs and regulates physiological responses to environmental and internal changes. Diuretic hormones 44 and 31, which are homologs of mammalian corticotropin-releasing factor (CRF) and calcitonin gene-related peptide (CGRP), respectively, control body fluid secretion in Drosophila. These neuropeptides and their receptors have multiple physiological roles, including the regulation of body-fluid secretion, sleep:wake cycle, internal nutrient-sensing, and CO₂-dependent response. This review discusses the physiological and behavioral roles of DH44 and DH31 signaling pathways, consisting of neuroendocrine cells that secrete DH44 or DH31 peptides and their receptor-expressing organs. Further research is needed to understand the regulatory mechanisms of the behavioral processes mediated by these neuroendocrine systems.

• Proceedings of the Korean Geotechical Society Conference
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• 2003.03a
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• pp.499-502
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• 2003

The purpose of this study is to understand the sliding characteristics of the infilling-joint surface using the new devised shear test apparatus with changeable slope for the original infilling materials and the infilling materials experienced cyclic freezing-thawing processes. Three types of the mother rock classified as the igneous rock, the metamorphic rock and the sedimentary rock and the infilling materials were collected for laboratory test. The cohesion according to the slope change of the rock joint shows large variation within ${\pm}$5 degrees but the internal friction angle shows appears the linear decreasing tendency. It is confirmed that the affecting factor of slope change of rock joint at the behavior of rock mass is larger than that of the infilling thickness. Test results show that the cohesion and the internal friction angle in 100 times of cyclic freezing-thawing processes are decreased about 50 percent compared with original one. A further study using various infillings materials would lead to a better understanding of the failure mechanism of rock mass by slope change of rock joint.

• Journal of Korean Academy of Nursing
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• v.45 no.1
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• pp.129-138
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• 2015

Purpose: The purpose of this study was to report the instrument modification and validation processes to make existing health belief model scales culturally appropriate for Korean Americans (KAs) regarding colorectal cancer (CRC) screening utilization. Methods: Instrument translation, individual interviews using cognitive interviewing, and expert reviews were conducted during the instrument modification phase, and a pilot test and a cross-sectional survey were conducted during the instrument validation phase. Data analyses of the cross-sectional survey included internal consistency and construct validity using exploratory and confirmatory factor analysis. Results: The main issues identified during the instrument modification phase were (a) cultural and linguistic translation issues and (b) newly developed items reflecting Korean cultural barriers. Cross-sectional survey analyses during the instrument validation phase revealed that all scales demonstrate good internal consistency reliability (Cronbach's alpha=.72~.88). Exploratory factor analysis showed that susceptibility and severity loaded on the same factor, which may indicate a threat variable. Items with low factor loadings in the confirmatory factor analysis may relate to (a) lack of knowledge about fecal occult blood testing and (b) multiple dimensions of the subscales. Conclusion: Methodological, sequential processes of instrument modification and validation, including translation, individual interviews, expert reviews, pilot testing and a cross-sectional survey, were provided in this study. The findings indicate that existing instruments need to be examined for CRC screening research involving KAs.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.6
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• pp.104-110
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• 2015

LED has added value as a lighting source in the illuminating industry because of its high efficiency and low power consumption. In LED production processes, the chip cutting process, which mainly uses a scribing process with a laser has an effect on quality and productivity of LED. This scribing process causes problems like heat deformation, decreasing strength. The inner laser method, which makes a void in wafer and induces self-cracking, can overcome these problems. In this paper, cutting sapphire wafer for fabricating LED chip using the inner laser scribing process is proposed and evaluated. The aim is to settle basic experiment conditions, determine parameters of cutting, and analyze the characteristics of cutting by means of experimentation.

• Journal of Korean Neurosurgical Society
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• v.49 no.1
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• pp.49-52
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• 2011

Traumatic intracranial aneurysms are rare, comprising 1% or less of all cerebral aneurysms. The majority of these aneurysms arise at the skull base or in the distal anterior and middle cerebral arteries or their branches following direct mural injury or acceleration-induced shearing force. We present a 50-year-old patient in whom subarachnoid hemorrhage (SAH) was developed as a result of traumatic aneurysm rupture after a closed craniofacial injury. Through careful evaluation of the three-dimensional computed tomography and conventional angiographies, the possible mechanism of the traumatic internal carotid artery trunk aneurysm is correlated with a hit injury by the bony protuberances on the anterior and posterior clinoid processes. This traumatic aneurysm was successfully obliterated with clipping and wrapping technique. The possibility of a traumatic intracranial aneurysm should be considered when patient with SAH demonstrates bony protuberances on the clinoid process as a traumatic aneurysm may result from mechanical injury by the sharp bony edges.

• Journal of Korean Society of Water and Wastewater
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• v.30 no.4
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• pp.417-425
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• 2016

Desalination is a key technology to overcome water shortage problem in a near future. High energy consumption is an Achilles' heel in desalination technology. Osmotically driven membrane processes like forward osmosis(FO) was introduced to address this energy issue. Characterizing membrane properties such as water permeability(A), salt permeability(B), and the resistance to salt diffusion within the support layer($K_{ICP}$) are very important to predict the performance of scaled-up FO processes. Currently, most of researches reported that the water permeability of FO membrane was measured by reverse osmosis(RO) type test. Permeating direction of RO and FO are different and RO test needs hydraulic pressure so that several problems can be occurred(i.e. membrane deformation, compaction and effect of concentration polarization). This study focuses on measuring water permeability of FO membrane by FO type test results in various experimental conditions. A statistical approach was developed to evaluate the three FO membrane properties(A, B, and $K_{ICP}$) and it predicted test result by the internal and external concentration polarization model.

• Korean Journal of Computational Design and Engineering
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• v.20 no.1
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• pp.1-10
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• 2015

Using BIM (Building Information Modeling)-based design information to analyze various engineering processes has been widely adopted in construction projects. However, since typical building permit processes often require traditional 2D-based design information for submission and to obtain building approval, there are some challenges in delivering such data thru BIM-based design information. This paper proposed a methodology to generate and meet information requirements for permit applications and approvals based on BIM-based design information. To that end, we analyzed the required information necessary to make submissions for building approvals using the Seumter system. We then suggested a process to collect the required information from BIM-based data, and classified this into two types: BIM-internal and BIM-external information requirements. In addition, we proposed three algorithms to extract and to match between extracted BIM data and BIM-internal information requirements using IFC(Industry Foundation Classes). The proposed methodology enables to ensure the efficiency and the accuracy when providing data for building permit review and approval.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.1124-1126
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• 2003

The processes of regional scales in the East Korean coastal waters were investigated by analysis of the Synthetic Aperture Radar (SAR) images taken by the European Research Satellites ERS-1, ERS-2 and Envisat. More than 500 quick look frames taken in 1991-2003 were examined to detect the frames with clearly surface expressions of oceanic phenomena. 26 ERS-1/2 SAR and 11 Envisat wide swath Advanced SAR (ASAR) frames were selected and obtained from the European Space Agency in a form of the precision high-resolution images. The following oceanic phenomena and processes were evident in the radar imagery through the Korean costal waters: fronts, currents, eddies, internal waves, island and ship wakes, oil pollution, etc. They manifested themselves in the field of sea surface roughness, their scale ranged from several tens meters to about 100 km. The most common morphology of these phenomena was a series of contrast dark or light curvilinear lines and bands. The joint analysis of the discussed SAR images with other satellite and in situ data supported and enhanced our interpretation of SAR signatures.