• Journal of Korea Technical Association of The Pulp and Paper Industry
• /
• v.37 no.4 s.112
• /
• pp.32-37
• /
• 2005

To Increase the productivity of a paper machine, the maximization of the machine speed is a kind of simple way As the machine speed increases, more intense wet pressing is required to persist the outlet consistency of press part and reduce the water removal of dryer part. With more intense pressing, there are concerns that the quality of paper will be affected. This study was carried out to evaluate the influence of wet-pressing on internal structure of paper, The nip pressure at the first and third nip in triple nip press was controlled. Paper structures, strength properties and pore properties were evaluated. As a result, first nip pressure more strongly influenced the paper structural properties than third nip pressure in triple nip pressing condition. Because of the high water content and low wet-web strength of paper web in first nip, increasing the first nip pressure induced the incipient crushing of wet-web and then caused a potential of web break during the following coating or printing processes.

• Proceedings of the KSME Conference
• /
• 2000.04a
• /
• pp.25-30
• /
• 2000

Residual stresses induced in U-bending and tube-to-tubesheet joining processes of PWR's steam generator row-1 tube were measured by X-ray method and Hole-Drilling Method(HDM). The stresses resulting from the Internal pressure and the temperature gradient in the steam generator were also estimated theoretically. In U-bent lesions, the residual stresses at extrados were induced with compressive stress(-), and its maximum value reached -319 MPa in axial direction at ${\psi}=0^{\circ}$ in position. Maximum tensile residual stress of 170MPa was found to be at the flank side at Position of${\psi}=90^{\circ}$, i.e., at apex region. In tube-to-tubesheet fouling methods, the residual stresses induced by the explosive joint method were found to be lower than that by the mechanical roll method. The gradient of residual stress along the expanded tube was highest at the. transition region, and the residual stress in circumferential direction was found to be higher than the residual stress in axial direction. Hoop stress due to an internal pressure between primary and secondary side was analyzed to be 76 MPa and thermal stress was 45 MPa.

• Journal of the Korean Wood Science and Technology
• /
• v.17 no.4
• /
• pp.26-34
• /
• 1989

This study was carried out to manufacture bark board from oak bark by new processes and to examine the physical and mechanical properties of the board. This process with no addition of adhesive used higher pressure and temperature than the conventional one and was applied with or without paraformaldehyde. The results are as follows: 1. The new manufacturing process allowed a good bark board with high absorption coefficient. 2. The best manufacturing process for the mechanical properties of bark board was paraformaldehyde 10%-$250^{\circ}C$-100kg/$cm^2$-3 minutes, (bending strength 40kg/$cm^2$, internal bonding strength 2kg/$cm^2$) and the best manufacturing process for both the mechanical properties of bark board and economic point of view was $250^{\circ}C$-100kg/$cm^2$-3 minutes (bending strength 28kg/$cm^2$, internal bonding strength 1.52kg/$cm^2$). 3. Bark board showed specific gravities from 0.94 to 1.03 and air dried moisture content 9.2% to 11.7%, but Bark board needed paraffin wax emusion treatment. 4. The absorption coefficient of bark boards had two peaks along with frequency; one in 200-400 cps, the other 1200-2000 cps. The former was low but the latter great.

• Journal of Korean Society for Quality Management
• /
• v.46 no.1
• /
• pp.153-168
• /
• 2018

Purpose: The balanced scorecard (BSC) has been adopted to evaluate factors affecting performances in organizational dealer marketing in Chinese cosmetics market. Four performance measures in BSC: learning & growth, internal business processes, customer performance, and financial performance are employed in our empirical study. Methods: We conducted surveys of dealers in a Chinese cosmetics company and used total 463 samples for analysis. Confirmatory factor analysis and structural equation model analysis were employed using AMOS 20.0. Results: This study found that internal business process had a positive relation with customer performance and learning and growth. Also, customer performance and learning & growth positively affected financial performances. Conclusion: This study has some academic and practical contributions in that the revised BSC model reflects the special aspects of Chinese cosmetics market and it can be used as a guide for companies in the Chinese cosmetics market to understand which factors are affecting performances.

• Molecules and Cells
• /
• v.25 no.3
• /
• pp.352-357
• /
• 2008

Osteoprotegerin (OPG) is a soluble decoy receptor that inhibits osteoclastogenesis and is closely associated with bone resorption processes. We have designed and determined the solution structures of potent OPG analogue peptides, derived from sequences of the cysteine-rich domain of OPG. The inhibitory effects of the peptides on osteoclastogenesis are dose-dependent ($10^{-6}M-10^{-4}M$), and the activity of the linear peptide at $10^{-4}M$ is ten-fold higher than that of the cyclic OPG peptide. Both linear and cyclic peptides have a ${\beta}$-turn-like conformation and the cyclic peptide has a rigid conformation, suggesting that structural flexibility is an important factor for receptor binding. Based on structural and biochemical information about RANKL and the OPG peptides, we suggest that complex formation between the peptide and RANKL is mediated by both hydrophobic and hydrogen bonding interactions. These results provide structural insights that should aid in the design of peptidyl-mimetic inhibitors for treating metabolic bone diseases caused by abnormal osteoclast recruitment.

• Proceedings of the Korea Inteligent Information System Society Conference
• /
• 2003.05a
• /
• pp.338-346
• /
• 2003

Information Technology (IT) and the internet have been major drivers the changes in all aspects of the business processes and activities. They have brought major changes to the financial statements audit environment as well, which in turn has required modifications in audit procedures. There exist, however, certain difficulties with current audit procedures especially for the assessment of the level of control risk. This assessment is primarily based on the auditors' professional judgment and experiences, not based on the objective hies or criteria. To overcome these difficulties, this paper proposes a prototype decision support model named CRAS-CBR using case based reasoning (CBR) to support auditors in making their professional judgment on the assessment of the level of control risk of the general accounting system in the manufacturing industry. To validate the performance, we compare our proposed model with benchmark performances in terms of classification accuracy for the level of control risk. Our experimental results showed CRAS-CBR outperforms a statistical model (MDA) and staff auditor performance in average hit ratio.

• Asia pacific journal of information systems
• /
• v.9 no.1
• /
• pp.165-191
• /
• 1999

The telecommunications of previous years have been utilized for internal usages, but those in current years have widely extended even to usages for Interorganizational Information System(IOIS) beyond its internal uses. Electronic Data Interchange(EDI), a subsidiary form of IOIS which permits interorganizational electronical exchanges of transaction documents through the telecommunications networks between and among computers, is expected to bring forth various innovative results with improved efficiency and productivity through the improvement and simplification of transaction processes, And it became needed and significant to review studies with practical values and necessity. This study is implemented on the basis of a judgement that Korea businesses can improve some of their structural problems of high costs by successfully adopting and implementing EDI system in their organizations. And it's also realized that more studies on the related subjects will benefit and be valuable for various applications. The major objectives of this research is to identify factors influencing in the implementation of EDI system by Korean business entities. Business which already implementation EDI system in their organizations were subjected to the survey. Also, this study intended to identify variables influencing in the implementation of EDI system and further provide directions needed in establishing or managing EDI system.

• Kidney Research and Clinical Practice
• /
• v.35 no.2
• /
• pp.69-77
• /
• 2016

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, and its pathogenesis is complex and has not yet been fully elucidated. Abnormal glucose and lipid metabolism is key to understanding the pathogenesis of DN, which can develop in both type 1 and type 2 diabetes. A hallmark of this disease is the accumulation of glucose and lipids in renal cells, resulting in oxidative and endoplasmic reticulum stress, intracellular hypoxia, and inflammation, eventually leading to glomerulosclerosis and interstitial fibrosis. There is a growing body of evidence demonstrating that dysregulation of 50 adenosine monophosphate-activated protein kinase (AMPK), an enzyme that plays a principal role in cell growth and cellular energy homeostasis, in relevant tissues is a key component of the development of metabolic syndrome and type 2 diabetes mellitus; thus, targeting this enzyme may ameliorate some pathologic features of this disease. AMPK regulates the coordination of anabolic processes, with its activation proven to improve glucose and lipid homeostasis in insulin-resistant animal models, as well as demonstrating mitochondrial biogenesis and antitumor activity. In this review, we discuss new findings regarding the role of AMPK in the pathogenesis of DN and offer suggestions for feasible clinical use and future studies of the role of AMPK activators in this disorder.

• Journal of Powder Materials
• /
• v.25 no.6
• /
• pp.507-513
• /
• 2018

This study investigates the viability of using a Na-ion battery with a tin(Sn) anode to mitigate the vulnerability caused by volume changes during discharge and charge cycling. In general, the volume changes of carbon material do not cause any instability during intercalation into its layer structure. Sn has a high theoretical capacity of $847mAh\;g^{-1}$. However, it expands dramatically in the discharge process by alloying Na-Sn, placing the electrode under massive internal stress, and particularly straining the binder over the elastic limit. The repeating strain results in loss of active material and its electric contact, as well as capacity decrease. This paper expands the scope of fabrication of Na-ion batteries with Sn by fabricating the binder as an auxetic structure with a unique feature: a negative Poisson ratio (NPR), which increases the resistance to internal stress in the Na-Sn alloying/de-alloying processes. Electrochemical tests and micrograph images of auxetic and common binders are used to compare dimensional and structural differences. Results show that the capacity of an auxetic-structured Sn electrode is much larger than that of a Sn electrode with a common-structured binder. Furthermore, using an auxetic structured Sn electrode, stability in discharge and charge cycling is obtained.

• Journal of Veterinary Science
• /
• v.21 no.3
• /
• pp.42.1-42.22
• /
• 2020

Regenerative medicine using stem cells from various sources are emerging treatment modality in several refractory diseases in veterinary medicine. It is well-known that stem cells can differentiate into specific cell types, self-renew, and regenerate. In addition, the unique immunomodulatory effects of stem cells have made stem cell transplantation a promising option for treating a wide range of disease and injuries. Recently, the medical demands for companion animals have been rapidly increasing, and certain disease conditions require alternative treatment options. In this review, we focused on stem cell application research in companion animals including experimental models, case reports and clinical trials in dogs and cats. The clinical studies and therapeutic protocols were categorized, evaluated and summarized according to the organ systems involved. The results indicate that evidence for the effectiveness of cell-based treatment in specific diseases or organ systems is not yet conclusive. Nonetheless, stem cell therapy may be a realistic treatment option in the near future, therefore, considerable efforts are needed to find optimized cell sources, cell numbers and delivery methods in order to standardize treatment methods and evaluation processes.