• Title/Summary/Keyword: Internal Organ

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A Case of Pulmonary Langerhans Cell Histiocytosis associated with Central Diabetes Insipidus in Adult -A case report - (성인에서 발견된 중추성 요붕증이 합병된 폐 랑게르한스 세포 조직구증 -1예 보고-)

  • Yoo Byung Su;Lee Jae Woong;Jo Tae Jun;Hong Ki Woo;Kim Kun Il;Lee Weon Yong;Kim Dong Gyu;Jun Sun Young
    • Journal of Chest Surgery
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    • v.38 no.12 s.257
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    • pp.866-869
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    • 2005
  • Langerhans Cell Histiocytosis (LCH) is a pathologic proliferation and infiltration of various organs by Langerhans' cells of unknown cause. Incidence rate of one million parties 3$\∼$4 is seen in young child but the incidence is not sure in adult. Organ systems involved by LCH may include skin, ear, bone marrow, liver, spleen, lung, pituitary gland - hypothalamus and Gl tracts. In case pituitary-hypothalamus axis are involved, diabetes insipidus happened. Primary Pulmonary Langerhans Cell Histiocytosis(PLCH) with uninvolvement of other organs is rare and accompanied diabetes insipidus is more rare. There are many cases of LCH with diabetes insipidus involve such as central nervous system except lung. PLCH accompany central diabetes insipidus is only 1 case. We report a case of PLCH that accompany central diabetes insipidus with literature investigation in Department of Thoracic and Cardiovascular Surgery, Hallym University.

Some Effects of Alternate Feeding of High-protein and Low-protein Diets to Growing Rats (고단백질(高蛋白質)과 저단백질(低蛋白質) 사료(飼料)의 교대급여(交代給與)가 쥐의 성장(成長)에 미치는 영향(影響))

  • Kim, Y.K.;Han, I.K.
    • Journal of Nutrition and Health
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    • v.7 no.4
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    • pp.1-5
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    • 1974
  • Forty weaning albino rats were used to find the effects of alternate feeding of high protein diet with different intervals on growth, feed efficiency, protein efficiency ratio, weight of some internal organ, protein digestibility and nitrogen balance. Results obtained are summarized as follows: 1. The growth rate and feed efficiency of group B fed high protein and low protein alternately in every other day was equal to that of A group fed medium protein diet daily. However, the rats fed high protein diet once every three days or every four days could not result in same growth that obtained by group A. 2. The protein efficiency ratio of each group was the same without significant difference. 3. The liver weight appeared to be in proportion to final body weight, but intestine weight and length appeared not to be affected by treatments. 4. The protein digestibility in each group was insignificant. However, urinary nitrogen loss of intermittent high protein feeding group was lower than that of control group and the nitrogen retention ratio decreased with increased nitrogen intake.

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DENS INVAGINATUS AND A VITAL MAXILLARY LATERAL INCISOR WITH LATERAL PERIODONTAL ABSCESS (생활력이 있는 상악측절치에서 치내치로 인한 측방치주농양이 형성된 증례)

  • Bae, Won-Su;Kim, Hyun-Jung;Nam, Soon-Hyun;Kim, Young-Jin
    • Journal of the korean academy of Pediatric Dentistry
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    • v.26 no.2
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    • pp.317-322
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    • 1999
  • Dens invaginatus is a developmental anomaly resulting from an invagination of the enamel organ. The incidence is highest with maxillary permanent lateral incisors. The reported occurrence ranges from 0.04 to 10%. This anomaly may involve the pulp and periapical tissues and cause pulpal inflammation, loss of vitality, apical and lateral periodontitis, periapical abscesses and cysts and stimulate internal resorption. Oehlers describes dens invaginatus as occurrence in three forms. In treating type 3 invaginatus, treatment strategy can be determined by considering the complexity and accessibility of invagination. In this case, showing simple invagination, it could be treated by simple endodontic treament confining to invagination without loss of vitality of tooth. After treatment of the present case, the results were as follows: 1. In type 3 dens invagiantus, if the tooth is vital and there is no evidence of communicating between invagination and pulp, we can save the vitality of the tooth and resolve the lesion by endodontic treament confining to the invagination. 2. In the invagination with opened apex, the closure of apex can be induced by apexification procedure doing this, we can avoid the neccessity of surgical intervention.

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Anti-obesity effect of Auricularia spp. (목이버섯의 항비만 효과)

  • Park, Kun Hee;Kim, Kil-ja;Jang, Kab Yeul;Park, Kimoon
    • Journal of Mushroom
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    • v.16 no.2
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    • pp.103-110
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    • 2018
  • The purpose of this study is to discover a food material having anti-obesity effects and to disseminate information on the effects of the material to people who are interested in anti-obesity. For this study, 11 kinds of Auricularia (wood ear) spp., including 8 strains of Auricularia auricula-polytricha, and 3 strains of A. auricula-judae, were presented by the Jeollanamdo Agricultural Research & Extension Services. 3T3-L1 (preadipocyte cell) was used for identifying the inhibition effect on adipocyte differentiation. As a result, this study found that all the extracts had slightly different degrees of inhibition effects on adipocyte differentiation. Among the A. auricula-polytricha strains, strain 21001 showed the most significant effect (4.58%), and the inhibition effect of strain 21002 (4.43%) was the greatest among A. auricula-judae strains. Overall, the inhibition effect of A. auricula-polytricha strains was greater than that of A. auricula-judae strains. The results of mRNA and protein analysis also demonstrated that the inhibition effect of A. auricula-polytricha 21001 was superior to that of any other strains. An in vivo study using 56 ICR mice (6w, male), was performed for 4 weeks. A. auricula-polytricha 21001, which exhibited the most significant effect in the in vitro study was used to compose six different types of feeds. Daily body weight gain of the high-fat diet containing 0.2% 21001 extract feeding group was $0.22{\pm}0.08g$ (*p < 0.05), and it was 31.25% lower than that of the high-fat diet feeding group ($0.32{\pm}0.06$). Internal organ weight measurement and blood analysis were performed immediately after animal sacrifice. The results proved that treatment with more than 0.1% of A. auricula-polytricha strain 21001 could significantly reduce (more than *p < 0.05) the weight of liver and epididymal fat, and levels of glucose, total cholesterol, AST, and ALT in blood.

Studies on the Fertilized Eggs in the Internal Reproductive Organ of the Silkworm Female Moth (Bombyx mori L.) (자아의 내부 생식기내 수정란에 관한 연구)

  • 윤종관;사기언
    • Journal of Sericultural and Entomological Science
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    • v.13 no.2
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    • pp.119-122
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    • 1971
  • The following results were obtained through the experiments and study of fertility for silkworm eggs in vagina, oviduct, and ovarial base. The sample eggs were collected after leaving silkworm moth for one week from the date of treatment was given to oviporm orifice of the silkworm moth by heated needle in order to discontinue laying eggs. Those sample silkworm moths were divided into two groups. The first group was under the condition of immediately after the couplation and the second group was under the condition of after the laying eggs in some extend, and both of them were completed couplation. The sample eggs were screened in order to confirm the degree of color which normally be observed as very characteristic during hibernating. 1. About 5% of silkworm out of the total sample were identified as having 1-2 eggs. (See table 1). But, the charasteristic colour of hibernating egg was not observed. The colour was not much different as that of eggs in ovarian duct. 2. Immediately after the couplation, the eggs were not found in vagina under the condition of immediately after the couplation. 3. About 10% of the sample under the condition of after laying eggs in some extend were found having eggs in vagina or oviduct. 4. About 2% of the sample silkworm moth under the condition of immediately after the couplation were found having I fertilized egg in oviduct. 5. No fertilized egg was found in ovarian tube. It seemed that sperm did not enter ovarian tube. 6. Almost the entire eggs were found in ovarian tube under the condition of immediately after the couplation. But, eggs under the condition of after laying eggs in some extend were found around oviduct and vagina due to the continuous movement of silkworm eggs towards oviporus orifice. 7. Sperm is mainly found around seminal receptacle and vagina, and sperm goes into micropyle together with silkworm eggs which were moving towards oviduct.

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Characteristics of Seed Structure and Seedling Development in Polygonatum odoratum Druce (둥굴레의 종자(種子) 구조(構造)와 출아(出芽) 특성(特性))

  • Kang, Jin-Ho;Kim, Dong-Il;Ryu, Yeong-Seop;Bae, Kee-Soo;Han, Kyung-Soo
    • Korean Journal of Medicinal Crop Science
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    • v.6 no.2
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    • pp.102-107
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    • 1998
  • Solomon's seal (Polygonatum odoratum) seedlings raised through its seeds can replace the rhizomes impelling higher cost for transplanting, This experiment was done to determine the seed characteristics and the germinating processes to give some information on bulk production of seedlings using the seeds. The external or internal morphology of seeds or seedlings grown in lab. or greenhouse was examined mainly with stereomicroscope. The external shape of Solomon's seal seed was hard seed-coat and orthotropous ovule with linear type embryo stretching to the center of seed. Germination proceeded through the several steps. The lower part of seed embryo having the primordia of bulbil and roots first grew before the bulbil and roots was developed from the primordia. The lower part of embryo was enlarged toward the endosperm of seed as soon as seed germinated. Then epicotyl was formed on the apex of bulbil. The epicotyl was elongated after at least 6-week chilling treatment for breaking its dormancy and the first leaf shape was affected by light intensity given during seedling emergence. The bulbil was the first organ of the rhizome used as tea or herb medicine.

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Comparative Studies of Pulsatile and Nonpulsatile Blood Flow during Cardiopulmonary Bypass (박동류 및 비박동류에 의한 체외순환의 비교)

  • Sun, Kyung;Baek, Kwang-Je;Kim, Yo-Han;Kim, Chang-Young;Kim, Kwang-Taek;Kim, Hark-Jei;Kim, Hyoung-Mook
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.182-192
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    • 1985
  • [here are so many reports that pulsatile blood flow provides physiologic organ perfusions during cardiopulmonary bypass. So, we compared the recent 30 cases undergoing cardiac surgery by Cobe-Stckert pulsatile roller pump with another 30 cases by Polystan nonpulsatile roller pump. Pulsatile flow was applied during aortic-cross clamping period when synchronized to internal EKG simulator, and perfusion mode was changed to continuous nonpulsatile flow after declamping of aorta. Age, sex, weight, and disease entities were comparable and operative techniques were similar between two groups. 1. There were no differences in average ACC time, ECC time, and Operation time. 2. Postoperative artificial respiration time was 6hrs 30mins in nonpulsatile group and 4hrs 48mins in pulsatile group, and detubation time after ventilator weaning was 2hrs 44mins in nonpulsatile group and 1hrs 43mins in pulsatile group. 3. Average pulse pressure was 8mmHg in nonpulsatile group and 55mmHg in pulsatile group, and a mean arterial pressure was 66.0mmHg in nonpulsatile group and 60.7mmHg in pulsatile group. 4. Mean urine-output during ACC;ECC period was 9.717.3;9.913.2ml/kg/hr in nonpulsatile group and 14.215.0;15.817.5 in pulsatile group [p<0, 05], and thereafter progressive decrease of differences in urine output between two groups until POD 2, and lesser amounts of diuretics was needed in pulsatile group during same postoperative period. Serum BUN/Cr level showed no specific difference and urine concentration power was well preserved in both groups. 5. Plasma proteins and other Enzymes showed no differences between two groups, but serum GOT/GPT level was higher in nonpulsatile group till POD 2. 6. Serum Electrolytes showed no differences between two groups. 7. WBC, RBC, Platelet counts, Hgb and Hct were not different and Coagulogram was well preserved in both groups. 8. Plasma free Hgb level was 7.09mg% in pulsatile group compared with 3.48mg% in pulsatile group on POD 1 but was normalized on POD 2. Gross hemoglobinuria after ECC was noted in 6 cases [20%] of pulsatile group and 4 cases [13%] of nonpulsatile group. 9. In both groups, most patients were included in NYHA class III to IV [28 cases;93% in nonpulsatile group, 22 cases;73% in pulsatile group] preoperatively, and well improved to class I to 11[22 cases; 73% in nonpulsatile group, 30 cases; 100% in pulsatile group] postoperatively. There were 7 operative mortalities in nonpulsatile group only, which were 5 cases of TOF with hepatic failure, 1 case of multiple VSDs with low out-put syndrome, and 1 case of mitral valvular heart disease with cardiomyopathy. We concluded that the new, commercially available Cobe-Stckert pulsatile roller pump device was safe, simple, and reliable.

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A Study on Relativity between Shi-Dong-Bing(是動病) and Five Su Points Related Symptoms of Liver Meridian of Foot Gworeum(足厥陰肝經) -Based on the Study of Zhen Jiu Jia Yi jing(鍼炎甲乙經)- (족궐음간경(足厥陰肝經) 오수혈 주치(主治)의 특성(特性)과 시동병(是動病)의 연관성(聯關性)에 관한 연구(硏究) -<침구갑을경(鍼灸甲乙經)>을 중심(中心)으로-)

  • Sung, Su-Min;Lee, Seong-Su;Oh, Se-Hyoung;Hwang, Min-Sub;Yoon, Jong-Hwa
    • Journal of Acupuncture Research
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    • v.23 no.3
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    • pp.57-65
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    • 2006
  • Objectives : It is known that the five Su points are very useful clinically. The following study was undertaken in order to find out the general characteristic and the origin of the five Su points. Methods: We investigated the relation of symptoms that are treated by five Su points and Shi-Dong Suo-Sheng-Bing(是動 所生病). The main reference book was Zhen Jiu Jia Yi jing(鍼灸甲乙經) and the author took Liver Meridian of Foot Gworeum(足厥陰肝經) as an example. Results : 1. Five Su point of Liver Meridian of Foot Gworeum(足厥陰肝經) treats Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum. It is peculiarity of Five Su point of Liver Meridian of Foot Gworeum, differed from the others acupoints. Symptoms of Shi-Dang-Bing appears with the abnormal pulsation of Merdian Gi(脈氣), and the special feature of Shi-Dang-Bing is the symptoms are consisted of disorders of whole body, trobles of an internal organ, and psychosomatic disorders. 2. In , it is described the part of pulse feeling for Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum(足厥陰肝經) as ‘A region that is 2 Chon(寸) from the basic digital joint of the first toe’. This region is agree with the acupoint of Liver Meridian of Foot Gworeum in , . And Haeng-gan(行間) Tae-chung(太衝), members of five Su-points of Liver Meridian of Foot Gworeum is situated the same region. So we suppose that the part of pulse feeling for Shi-Dong-Bing of Liver Meridian of Foot Gworeum is transformed into Haeng-gan(行間) Tae-chung(太衝), among the five Su points.

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The Clinical Study of Biyun(sinusitis) in Children (소아비연(小兒鼻淵)에 대(對)한 임상적(臨床的) 연구(硏究))

  • Park Eun-Jeong;Lee Hae-Ja
    • The Journal of Pediatrics of Korean Medicine
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    • v.12 no.1
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    • pp.111-131
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    • 1998
  • 1. In oriental medicine, the case of sinusitis can be explained, not only external invasion such as PUNG HAN(wind-cold), PUNG YUL(wind-hot), SHUP YUL(damp-heat), but also functional disorder of internal organ such as spleen(脾), lung(肺), kidney(腎) The western medicine classified the cause of sinusitis as two factors. That is bacterial infection factor-Haemophilus influenza, streptococcus pyogeues, streptococcus pneumonia- and viral infection factor-Rhinovirus, parainfluenza, Echo28, Coxsacki21, Sinusitis is complicated to allergic rhinitis, chronic otitis media purulent, chronic tonsilitis, sinubronchitis. On the condition of nasal septum deformity, turbinates deformity, nasal septum deviation, sinusitis can be developed. the predisposing factors of sinusitis is swimming, air pollution, malnutrition, shortage of immunity.2. According to survey, sinusitis occurred that children from 4 to 12 years old and from 5 to 7 years old occupied 70% 3. From the past history data, they experienced chronic tonsillar hypertropy(20%), otitis media, atopic dermatitis, allergic rhinitis, bronchial asthma, pneumonia, bronchiolitis, chronic sore throat, urticaria, milk allergy in sequence. 4. the symptoms of sinusitis is nasal obstruction, postnasal dripping, purulunt(yellow)or white discharge, cough, nose bleeding in sequence. nasal obstruction take the portion of 95%, postnasal dripping 65%, night time or early morning cough 60%. 5. The suffering period of sinusitis is 6 month minimum, 4 years maximum, most cases are included in a year. The suffering period of children was shorter than adult. 6. Diagnosis depend on inspection of nasal cavity, postnasal dripping, X-ray finding. 75% of patient(15case) showed both maxillary sinusitis, 25%(5cases) showed left or right maxillary sinusitis. 7. Treatment of oriental medicine, consist of Herb-medicine, acupuncture and exposing of Lazer beam. Kamihyunggyeyungyotang(加味荊芥蓮翹湯) is administered mainly as the medical therapy, Kamigwaghyangjeungkisan(加味藿香正氣散) Kimizwakwieum(加味左歸飮), Kamihyangsosan(加味香蘇散) is administered for a additional symptoms which occurred by influenza recurrence. Kamijeonxibackchulsan(加味錢氏白朮散) is administered to treat gastro-intestine trouble patients who have sinusitis. 8. The period of treatment is varied with patient conditions and X-ray finding. The minimal period is 35days, maximal period is 202days. So it took about 86days in average and about 50% of patient(10cases) is recovered in one or two month.

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Effect of Blood Pressure on Contractility of Vascular Smooth Muscle and Endothelium-Dependent Relaxation

  • Suh, Suk-Hyo;Park, Yee-Tae;Lee, Dong-Chul;Seo, Pil-Won;Kim, Ki-Whan
    • The Korean Journal of Physiology
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    • v.29 no.2
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    • pp.279-289
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    • 1995
  • This study was designed 1) to develop a hypertensive animal model in which the blood pressures (BPs) of symmetric regions (right and left upper extremities) are significantly different and 2) to test the effect of BP per se on the contractility and endothelium-dependent relaxation of vascular smooth muscle. Rabbits were anesthetized with sodium pentobarbital and ventilated with room air via animal respirator. The transverse aorta was exposed through the left second intercostal space and the lumen of the aorta was narrowed partially by ligation using 3-0 silk and a probe at a point between the origins of the brachiocephalic trunk and the left subclavian artery. Four to eight weeks postoperatively, BPs were measured in the carotid artery as the high BP area (proximal to coactation site) and in the femoral artery as the low BP area (distal to coarctation site). In the animal model, pressure-overload hypertension was developed and the BP of the right subclavian artery was higher than that of the left subclavian artery. The concentrations of circulating epinephrine, norepinephrine, angiotensin I, and angiotensin II were measured. The right and left subclavian arteries and their branches were used for isometric tension recording in organ baths and their responsiveness to phenylephrine, serotonin, acetylcholine, and sodium nitroprusside were examined. The BPs of carotid and femoral artery in control animals were $116{\pm} 12/75{\pm}9\;mmHg (mean ${\pm}SEM$) and $130{\pm}16/68{\pm}9\;mmHg$ respectively, while those of carotid and femoral artery in the hypetensive animals were $172{\pm}6/111{\pm}10\;mmHg$ and 136{\pm} 4/100 {\pm}9\;mmHg$ respectively. There were no significant differences in the concentrations of circulating epinephrine, norepinephrine, angiotensin I, and angiotensin II between controls and the animal models. No significant differences were found in the vascular sensitivities to phenylephrine and serotonin between the high pressure-exposed vessels and the low pressure-exposed vessels. However, the endothelium-dependent relaxation to acetylcholine and nitroprusside-induced relaxation showed significant differences between the high pressure-exposed and the low pressure-exposed subclavian arteries. From the above results, we suggest that the contractility of vascular smooth muscle is unchanged by the elevated pressure per se. However, the endothelium-dependent relaxation to acetylcholine and the nitroprusside-induced relaxation are attenuated by pressure.

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