• 대한기계학회논문집A
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• 제23권6호
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• pp.961-967
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• 1999

A model is constructed to evaluate the mode III stress intensity factor(SIF) for orthotropic three-layered material with a center crack subjected to uniform anti-plane shear loading. A mixed boundary value problem is formulated by Fourier integral transform method and a Fredholm integral equation of the second kind is derived. The integral equation is numerically analyzed to evaluate the effects of the ratio of shear modulus, strength of each layer and crack length to layer thickness on the stress intensity factor.

• 대한기계학회논문집A
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• 제29권5호
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• pp.734-742
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• 2005

The present study proposes the integrity evaluation model for a straight pipe with local wall thinning defect, which reflects the characteristics of training shape and loading condition in the Piping of nuclear power plant. For this purpose, a series of finite element analyses are performed under various defect geometries and loading conditions, and real pipe experiment data performed previously is employed. The model includes the effect of thinning length as well as thinning depth and width, and also it considers the combined loading effect between internal pressure and bending moment. The proposed model has been validated using the results of finite element analysis and pipe experiment data. The results indicate that the proposed model provides more reliable predictions of pipe failure than the current existing model, in terms of accuracy, consistency, and conservativeness of results.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 봄 학술발표회 논문집(I)
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• pp.691-696
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• 1999

This paper is aimed to investigate flexural rehabilitation effect o pre-loaded reinforced concrete beams strengthened by carbon fiber sheet. Main Test parameters are reinforcement ratio and the magnitude of pro-loading and seven test beams are analyzed rehabilitation effect by carbon fiber sheet, load-deflection, failure mode, stress of reinforcing bar by the magnitude of pre-loading. Test results show that internal force was showed pre-loaded specimens lower than no-loaded specimens during rehabilitation and changing stiffness was showed in the same was and failure mode showed brittle failure from all specimens.

• Macromolecular Research
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• 제9권6호
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• pp.297-302
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• 2001

Rice starch was incorporated into linear low density polyethylene (LLDPE) using a Brabender Plastic-Corder internal mixer at a temperature of 140$\^{C}$ and 40 rpm. The starch loading was varied from 0 to 30% with 5 intervals. Studies on brabender torque development, mechanical properties and water absorption were investigated. The starch loading did not influence the brabender torque significantly. With respect to mechanical properties; the tensile strength and elongation at break decrease with increasing starch loading. The Young's modulus also increases with the starch filling. Mechanical properties were deteriorated as the starch absorbed moisture. The rate of water absorption was dependent on the starch filling in the composites. The scanning electron microscope (SEM) analysis was performed for the tensile fracture surfaces and it revealed the starch agglomeration and a poor dispersion of starch in the LLDPE matrix.

• Steel and Composite Structures
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• 제51권2호
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• pp.139-151
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• 2024

In this research, a semi-analytical solution is presented for computing mechanical displacements and thermal stresses in rotating thick cylindrical pressure vessels made of functionally graded material (FGM). The modulus of elasticity, linear thermal expansion coefficient, and density of the cylinder are assumed to change along the axial direction as a power-law function. It is also assumed that Poisson's ratio and thermal conductivity are constant. This cylinder was subjected to non-uniform internal pressure and thermal loading. Thermal loading varies in two directions. The governing equations are derived by the first-order shear deformation theory (FSDT). Using the multilayer method, a functionally graded (FG) cylinder with variable thickness is divided into n homogenous disks, and n sets of differential equations are obtained. Applying the boundary conditions and continuity conditions between the layers, the solution of this set of equations is obtained. To the best of the researchers' knowledge, in the literature, there is no study carried out bi-directional thermoelastic analysis of clamped-clamped rotating FGM thick-walled cylindrical pressure vessels under variable pressure in the longitudinal direction.

• Journal of Chest Surgery
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• 제46권6호
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• pp.457-460
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• 2013

Dynamic left ventricular (LV) outflow tract obstruction is a characteristic feature of hypertrophic cardiomyopathy; however, it can also occur in association with hyperdynamic LV contraction and/or changes in the cardiac loading condition, even in a structurally normal or near-normal heart. Here, we report a case of anemia-induced systolic anterior motion of the mitral valve and the resultant intraventricular obstruction in a patient who underwent coronary artery bypass grafting and suffered from anemia associated with recurrent gastrointestinal bleeding.

• Journal of Animal Science and Technology
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• 제49권2호
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• pp.161-170
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• 2007

본 연구에서는 생산성이 인정된 모돈 F1(YL)에 종료웅돈(Terminal Sire)으로 Duroc종 이외에 생산성 저하에 많은 영향을 미치지 않을 것으로 판단되는 최종 종료웅돈(Terminal Sire) Berkshire종과 Berkshire×Duroc(F1)을 YL(♀) 교배시켜 생산된 비육돈(YLD, YLB, YLBD)의 성장과 육질을 비교 분석 하였다. 성장형질에서는 YL(♀)×BD(♂)가 YL(♀)×D(♂)보다 우수하였으며, 조사된 성장형질 전체에서 유의적인 차이(p<0.05)를 보였다. 육질에서도 pH, 보수력, 육색이 다른 비육돈 보다 유의적으로(p<0.05) 우수하였고, 돼지 육질의 표준이 되는 등심조지방 함량에서 YL(♀)×BD(♂)가 유의적으로 우수하였다. 교배조합별 육색에서는 YL(♀)×BD(♂)가 대체로 명도와 적색도가 높았으며, 지방산 조성에 있어서는 불포화 지방산의 비율이 높은 것으로 나타났다. 따라서, 성장형질에서는 YL(♀)×BD(♂)가 비교 대상의 교배조합에 비해 우수하였으며, 육질에서도 YL(♀)×D(♂) 보다 좋거나 같아 비육돈 교배조합(YLBD)으로서의 이용가치가 있을 것으로 사료된다. 하지만 본 연구의 경우 경남 첨단양돈연구소의 계통조성이 완료된 American Berkshire종을 이용하여 경남의 경우 경남 첨단양돈연구소를 활용하여 별도의 비용이 없이 YLBD를 생산이 가능하겠으나, 다른 지역의 경우 Berkshire의 계통 조성하여 활용할 경우 기존의 종료웅돈 Duroc종을 계통 조성하는 비용만큼 더 소요될 것이라 사료된다.

• Geomechanics and Engineering
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• 제20권1호
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• pp.29-41
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• 2020

It is extremely important to obtain rock strength parameters for geological engineering. In this paper, the evolution of sandstone cohesion and internal friction angle with plastic shear strain was obtained by simulating the cyclic loading and unloading tests under different confining pressures using Particle Flow Code software. By which and combined with the micro-crack propagation process, the mesoscopic mechanism of parameter evolution was studied. The results show that with the increase of plastic shear strain, the sandstone cohesion decreases first and then tends to be stable, while the internal friction angle increases first, then decreases, and finally maintains unchanged. The evolution of sandstone shear strength parameters is closely related to the whole process of crack formation, propagation and coalescence. When the internal micro-cracks are less and distributed randomly and dispersedly, and the rock shear strength parameters (cohesion, internal friction angle) are considered to have not been fully mobilized. As the directional development of the internal micro-fractures as well as the gradual formation of macroscopic shear plane, the rock cohesion reduces continuously and the internal friction angle is in the rise stage. As the formation of the macroscopic shear plane, both the rock cohesion and internal friction angle continuously decrease to a certain residual level.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4915-4918
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• 2014

Background and Aims: Advances in the treatment of cervical cancer over the last decade have predominantly involved the development of genes directed at molecular targets. Gene therapy is recognized to be a novel method for the treatment of cervical cancer. Genes can be administered into target cells via nanocarriers. This study aimed to develop systemically administrable nano-vectors. Floate (Fa) containing gene loaded nanoparticles (NPs) could target HeLa human cervical cancer cells through combination with receptors on the cells to increase the nuclear uptake of genetic materials. Methods: Fa was linked onto Poly (ethylene glycol)-b-poly (D, L-lactide) (PEG-PLA) to form Fa-PEG-PLA, and the resulting material was used to load plasmids of enhanced green fluorescence protein (pEGFP) to obtain gene loaded nanoparticles (Fa-NPs/DNA). Physical-chemical characteristics, in vitro release and cytotoxicity of Fa-NPs/DNA were evaluated. The in vitro transfection efficiency of Fa-NPs/DNA was evaluated in HeLa cells and human umbilical vein endothelial cells (HUVEC). PEG-PLA without Fa was used to load pEGFP from NPs/DNA as a control. Results: Fa-NPs/DNA has a particle size of 183 nm and a gene loading quantity of 92%. After 72h of transfection, Fa-NPs/DNA displayed over 20% higher transfection efficiency than NPs/DNA and 40% higher than naked DNA in HeLa cells. However, in HUVECs, no significant difference appeared between Fa-NPs/DNA and NPs/DNA. Conclusions: Fa-PEG-PLA NPs could function as excellent materials for gene loading. This nano-approach could be used as tumor cell targeted medicine for the treatment of cervical cancer.

• 한국구조물진단유지관리공학회 논문집
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• 제26권4호
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• pp.11-19
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• 2022

본 연구에서는 기계식 커플러의 이음성능을 향상시키기 위해 다른 접합방식을 가진 두 가지의 새로운 커플러를 개발하였다. 두 가지 방식의 기계식 이음장치에 대하여 응력 해석을 수행하였다. 커플러의 재료특성, 접합방식, 내부 조임쇠의 경사길이를 변수로 최대 인장강도의 영향성을 분석하기 위해 일축인장시험을 수행하였다. 일축인장시험결과를 만족하는 시험체를 대상으로 KS D 0249에 의거하여 정적내력시험 및 반복하중 시험을 수행하였다. 이에 대한 연구결과는 다음과 같다. (1) 커플러의 인장강도와 내부 조임쇠의 경사길이는 최대 인장강도에 영향을 끼친다. (2) 연결 방식에 따라 접합된 철근의 강성, 슬립량, 강성감소율에 영향이 있다. 연구결과는 새롭게 제안된 향상된 기계식 이음장치의 현장 적용에 대한 가능성을 검증하였다.