• The Journal of Internal Korean Medicine
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• v.18 no.1
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• pp.97-113
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• 1997

The present experiment was designed to investigate the effects of Sambutang water extracts on the serum cholesterol levels and the cardiovascular system in the experimental animals. Thus, the changes of blood pressure and heart rate were measured after oral administration. Measurment of Mortality rate was observed for measuring the effect of Sambutang water extract. Sambutang water extract against pulmonary thromboembolism induced by collagen the mixture(0.1 ml/10 g, 2 mg/kg) plus serotonin(5 mg/kg) in mouse. The effect of Sambutang water extract was examined by observing the change of collagen-induced platelet aggregation, coagulation activity, ex vivo and in vitro fibrinolytic activity of euglobulin fraction in rats. The results were summarized as follows. 1. Sambutang decreased the serum cholesterol levels in rats. 2. Sambutang dropped the blood pressure in spontaneous hypertensive rat. 3. The drug increased the auricular blood flow in rabbit. 4. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 5. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 6. The drug inhibited the platelet aggregation in rat. 7. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 8. The drug increased the antithrombin activity in rat and the fibrinogen lysis time was reduced and lysis area was increased. 9. Sambutang reduced fibrinogen lysis time of rat in vitro assay. According to the above mentioned results. Sambutang increased the blood flow and dropped the blood pressure by the dilation of blood vessel. And the drug presented the antithrombin activity, inhibited the platelet aggregation.

• The Journal of Internal Korean Medicine
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• v.19 no.2
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• pp.88-106
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• 1998

This study was designed to elucidate the antiinflammatory, cardiovascular, antithrombotic, and analgesic effect of Sambitang. The antiinflammatory effects was measured by the method of carrageenin induced edema, protein leakage test using CMC-pouch, and the effect of Sambitang on the cardiovascular system was observed by the change of flow rate of Ringer solution in the vascular system in the ear of rabbit, and the contraction and dilatation of rat tail artery. Death rate, platelet aggregation, plasma coagulation activity was observed for the measurement of the anticoagurative effect of Sambitang, and the analgesic effect was measured by the acetic acid method and hot plate method. The result was as follows: 1. Sambitang administration, edema and protein leakage was significantly decreased. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 4. The drug inhibited the death rate of mouse which was led to thromboembo- lism by serotonin and collagen. 5. The drug inhibited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The slight anagesic effect of Sambitang extract was confirmed by the observation of writhing syndrome, paw licking time, and escape time.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.3
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• pp.271-277
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• 2014

Internal structures, especially those located in the upstream of a reactor core, may have a significant influence on the core inlet flow rate distribution depending on both their shapes and the relative distance between the internal structures and the core inlet. In this study, to examine the effect of the reactor internal structure geometry treatment method on the prediction accuracy for the scale-down APR+ flow distribution, simulations with real geometry modeling were conducted using ANSYS CFX R.14, a commercial computational fluid dynamics software, and the predicted results were compared with those of the porous medium assumption. It was concluded that the core inlet flow distribution could be predicted more accurately by considering the real geometry of the internal structures located in the upstream of the core inlet. Therefore, if sufficient computational resources are available, an exact representation of these internal structures, for example, lower support structure bottom plate and ICI nozzle support plate, is needed for the accurate simulation of the reactor internal flow.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2003.11a
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• pp.387-391
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• 2003

In this paper, a double cylindrical type superposed silent discharge type ozonizer which internal electrode can be produced a vacuum has been designed and manufactured Discharge and ozone generation characteristics have been investigated in accordance with output voltage of power supply, flow-rate, discharge power and vacuum of internal electrode.

• Proceedings of the KSME Conference
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• 2001.06e
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• pp.696-701
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• 2001

The performance and the internal flow of the impeller of the centrifugal chiller compressor with refrigerant R12 as working fluid were studied numerically, using CFD code, CFX-Tascflow, which is commercially available. In this numerical study, the thermodynamic and transport properties of the refrigerant gas were generated by the property program of NIST and linked with main program to extend the capability of the code to refrigerant gases. Numerical study was applied to several mass flow rates near the design mass flow rate at constant rotating speed. Overall performance and flow characteristics of the impeller at impeller exit were investigated. The results were physically reasonable and showed good agreement with experimental measurement at the design flow rate.

• 한국가시화정보학회:학술대회논문집
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• 2005.12a
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• pp.111-116
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• 2005

An automobile engine has the Positive Crankcase Ventilation system (PCV system) for preventing air pollution as the environmental problem is important In this system, a PCV valve is the most important component to control the flow rate of Blowby gas which is generated by various engine powers. But, in the working place, the design of a PCV valve is very difficult because of interaction between fluid and solid motions. In this study, we investigated fluid flow characteristics using re-meshing method of a CFD technique to simulate spool behavior. As the results, a spool is periodically oscillated with time and is largely oscillated in proportion to the differential pressure between inlet and outlet. And, although the velocity at the orifice increases with the differential pressure, the flow rate of the outlet decreases. This research may give PCV designers visual flow information to help them

• The Journal of Internal Korean Medicine
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• v.26 no.3
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• pp.596-604
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• 2005

Objectives : Geopungjeseub-tang(Gufengchushi-tang) has been used in oriental medicine for many centuries as a therapeutic agent for hemiplegia caused by deficiency of qi(氣虛) and damp phlegm(濕痰). This study was performed to evaluate effects of Geopungjeseub-tang extract(GJT) on hemodynamics[regional cerebral blood flow(rCBF), pial arterial diameter(PAD), mean arterial blood pressure(MABP), heart rate(HR)] in normal rats and in rats with cerebral ischemia by middle cerebral artery(MCA) occlusion. Also, effects of adrenergic ${\beta}-receptor$, cyclooxygenase on response to GJT were evaluated. Methods : Laser-doppler flowmetry(LDF) measured changes of rCBF, MABP and HR. Video microscope and width analyzer measured changes in PAD. Results : rCBF and PAD increased after treatment with GJT(10mg/kg, i.v.) during the period of cerebral reperfusion, and pretreatment with indomethacin raised rCBF and PAD increased after treatment with GJT during the same period as above. Pretreatment with propranolol decreased rCBF, but increased after GJT treatment, but raised PAD increased after GJT treatment during this period of reperfusion. Conclusion : CR caused diverse responses were observed in rCBF and PAD after treatment with GJT. ACF action is mediated by adrenergic ${\beta}-receptor$ and cyclooxygenase. Result suggest that GJT has an anti-ischemic effect through the improvement of cerebral hemodynamics and has theraputic potential for cerebral apoplexy.

• International Journal of Fluid Machinery and Systems
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• v.3 no.2
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• pp.102-112
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• 2010

Artificial heart pumps have attracted the attention of researchers around the world as an alternative to the organ used in cardiac transplantation. Conventional centrifugal pumps are no longer considered suitable for long-term application because of the possibility of occurrence of blood leakage and thrombus formation around the shaft seal. To overcome this problem posed by the shaft seal in conventional centrifugal pumps, the magnetically suspended centrifugal pump has been developed; this is a sealless rotor pump, which can provide contact-free rotation of the impeller without leading to material wear. In Europe, clinical trials of this pump have been successfully performed, and these pumps are commercially available. One of the aims of our study is to numerically examine the internal flow and the effect of leakage flow through the gap between the impeller and the pump casing on the performance of the pump. The results show that the pressure head increases compared with the pump without a gap for all flow rates because of the leakage of the fluid through the gap. It was observed that the leakage flow rate in the pump is sufficiently large; further, no stagnant fluid or dead flow regions were observed in the pump. Therefore, the present pump can efficiently enhance the washout effect.

• The KSFM Journal of Fluid Machinery
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• v.15 no.2
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• pp.57-62
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• 2012

The constant air volume flow fan can maintain constant flow rate to the wide range of exit pressure. Therefore, the use of this fan is increasing recently for ventilation of high building. Brushless DC motor is adopted to this fan because that has advantages of compactness and performance. But this type of motor protrude from impeller hub side to fan inlet. The Impeller inlet flow is influenced by size of this obstacle called hub. In this paper, the influence of hub shape on the fan performance characteristics are experimentally and numerically analyzed. CFX 12.0 is used to perform the fan internal flow analysis and numerical results are compared with the experiments. Depending on hub shape, internal loss is generated and the performance and efficiency are reduced. The best performance is occurred around $h/b_1$ = 0.25. The results of this study will be contribute to initial design of constant air volume flow fan development.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.10 no.6
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• pp.763-772
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• 1998

The effects of an inserted coil on flow patterns and heat transport performance for a horizontal rotating heat pipe have been studied experimentally. Especially, the present study is to see an internally inserted helical coil inside a RHP would lead to the same kind of results as internal fins. Visualization test conducted for an acryl tube, charged water with at a volumetric rate of 20%. When the flow kept pool regime at a low RPM(less than 1,000 RPM), the movement of coil forced the water to flow in axial direction. But this pumping effect of coil disappeared, when the pool regime changed to annular one which could be created by increasing RPM. The pumping effects for RHP with an inserted coil resulted enhancement both in condensation heat transfer coefficient and heat transport limitation, as obtained in case of using internal fins. But all these effects became negligible in the range of higher RPM(above 1,000∼1,200) with the transition of flow regime to annular flow.