• 제목/요약/키워드: Internal Environmental Factor

검색결과 233건 처리시간 0.028초

위축성 위염과 장상피화생의 호전에 영향을 미치는 인자에 대한 전향적 연구 (Predictive Factors for Improvement of Atrophic Gastritis and Intestinal Metaplasia: A Long-term Prospective Clinical Study)

  • 황영재;김나영;윤창용;권민구;백성민;권영재;이혜승;이제봉;최윤진;윤혁;신철민;박영수;이동호
    • 대한상부위장관⦁헬리코박터학회지
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    • 제18권3호
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    • pp.186-197
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    • 2018
  • Background/Aims: To investigate the predictive factors for improvement of atrophic gastritis (AG) and intestinal metaplasia (IM). Materials and Methods: A total of 778 subjects were prospectively enrolled and followed up for 10 years. Histological analysis of AG and IM was performed by using the updated Sydney system. To find the predictive factors for reversibility of AG and IM, 24 factors including genetic polymorphisms and bacterial and environmental factors were analyzed. Results: In all subjects, the predictive factor by multivariate analysis for improvement of both antral and corpus AG was successful eradication. The predictive factors for improvement of antral IM were age and successful eradication. The predictive factor for improvement of corpus IM was successful eradication. In patients with Helicobacter pylori infection, age and cagA were predictive factors for improvement of AG and IM. In patients with H. pylori eradication, monthly income and cagA were predictive factors for improvement of AG and IM. Conclusions: H. pylori eradication is an important predictive factor of regression of AG and IM and would be beneficial for the prevention of intestinal-type gastric cancer. Young age, high income, and cagA are additional predictive factors for improving AG and IM status. Thus, various factors affect the improvement of AG and IM.

Collapse assessment and seismic performance factors in tall tube-in-tube diagrid buildings

  • Khatami, Alireza;Heshmati, Mahdi;Aghakouchak, Ali Akbar
    • Earthquakes and Structures
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    • 제19권3호
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    • pp.197-214
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    • 2020
  • Diagrid structures have been introduced as a fairly modern lateral load-resisting system in the design of high-rise buildings. In this paper, a novel diagrid system called tube-in-tube diagrid building is introduced and assessed through pushover and incremental dynamic analyses. The main objectives of this paper are to find the optimum angle of interior and exterior diagrid tube and evaluate the efficiency of diagrid core on the probability of collapse comparing to the conventional diagrid system. Finally, the seismic performance factors of the proposed system are validated according to the FEMA P695 methodology. To achieve these, 36-story diagrid buildings with various external and internal diagonal angles are designed and then 3-D nonlinear models of these structures developed in PERFORM-3D. The results show that weight of steel material highly depends on diagonal angle of exterior tube. Adding diagrid core generally increases the over-strength factor and collapse margin ratio of tall diagrid buildings confirming high seismic safety margin for tube-in-tube diagrid buildings under severe excitations. Collapse probabilities of both structural systems under MCE records are less than 10%. Finally, response modification factor of 3.0 and over-strength factor of 2.0 and 2.5 are proposed for design of typical diagrid and tube-in-tube diagrid buildings, respectively.

영유아 식행동 검사도구 개발 및 타당도 검정 (The Development and Validation of Eating Behavior Test Form for Infants and Young Children)

  • 한영신;김수안;이윤나;김정미
    • 대한지역사회영양학회지
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    • 제20권1호
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    • pp.1-10
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    • 2015
  • Objectives: This study was conducted to develop and validate Eating Behaviors Test form (EBT) for infants and young children, including eating behaviors of their parents and parental feeding practices. Methods: Draft version of EBT form was developed after a pretest on 83 mothers. It was consisted of 42 questions including 3 components; eating behavior of children, eating behavior of parents, and parental feeding practices. Using these questionnaires, the first survey was conducted on 320 infants and children, 1 to 6 year old, for exploratory factor analysis, and the second survey was collected on 731 infants and children for confirmatory factor analysis. Results: Exploratory factor analysis on 42 questions of EBT form resulted in 3 factor model for children's eating behavior, 3 factor model for parents' eating behavior, and 1 factor model for parental feeding practices. Three factors for children's eating behavior could be explained as follows; factor 1, pickiness (reliability ${\alpha}=0.89$; explanation of variance=27.79), factor 2, over activity (${\alpha}=0.80$, explanation of variance=16.51), and factor 3, irregularity (${\alpha}=0.59$, explanation of variance=10.01). Three factors for mother's eating behavior could be explained as follows; factor 1,irregularities (${\alpha}=0.73$, explanation of variance=21.73), factor 2, pickiness (${\alpha}=0.65$, explanation of variance= 20.16), and factor 3, permissiveness (${\alpha}=0.60$, explanation of variance=19.13). Confirmatory factor analysis confirmed an acceptance fit for these models. Internal consistencies for these factors were above 0.6. Conclusions: Our results indicated that EBT form is a valid tool to measure comprehensive eating and feeding behaviors for infants and young children.

다변량 해석기법을 이용한 인천연안해역의 수질평가 (The Evaluation of Water Quality in Coastal Sea of Incheon Using a Multivariate Analysis)

  • 김종구
    • 한국환경과학회지
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    • 제15권11호
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    • pp.1017-1025
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    • 2006
  • This study was conducted to evaluate characteristic of water duality in coastal sea of Incheon using a multivariate analysis. The analysis data in coastal sea of Incheon was aquired by the NFRDI data which was surveyed from March 1997 to November 2003. Eleven water quality parameters were determined on each survey The results were summarized as follow : Water quality in Incheon coastal sea could be explained up to 64.62% by three factors which were included in loading of fresh water and nutrients by the land(36.98%), seasonal variation(16.19%), and internal metabolism (11.24%). The results of time series analysis by factor score, in case of factor 1, station 1 influenced by Han river was shown to high factor score and station 3 located by outer sea was shown to low factor score. In case of factor 2, station 1 was appeared to high variation and station 3 was appeared to low variation. The result of cluster analysis by station was classified into three group that has different water quality characteristics. Especially, station 1 which affected by Han river and station 4 which affected by sewage treatment plant was appeared to considerable water quality characteristics against other station. In yearly cluster analysis, three group was classified and water quality in 2003 years due to high precipitation was different to another year. It could be suggested from these results that it is important to control discharge of fresh water by Han rivet and sewage treatment plant for water quality management of coastal sea of Incheon.

모래지반에서 팽창각에 따른 연속기초와 원형기초의 지지력계수 Nγ와 형상계수에 대한 수치해석 연구 (Numerical Studies on Bearing Capacity Factor Nγ and Shape Factor of Strip and Circular Footings on Sand According to Dilatancy Angle)

  • 김동준;윤준웅;지성현;최재형;이진선;김동수
    • 한국지반공학회논문집
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    • 제30권1호
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    • pp.49-63
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    • 2014
  • 모래지반의 지표면에 위치한 거친 바닥면을 가진 강체 연속기초와 원형기초에 대하여 수치해석을 이용하여 팽창각 변화에 따른 지지력계수 $N_{\gamma}$와 형상계수를 구하였다. 양해법(explicit method)에 기반한 유한차분해석을 이용하여 지지력계수를 산정하기 위한 수치모델과 해석절차를 개발하고, Mohr-Coulomb 소성모델을 이용하여 다양한 내부마찰각(${\phi}$)과 팽창각(${\psi}$) 범위에 대하여 지지력계수를 도출하였다. 팽창각이 감소됨에 따라 지지력도 감소하는 것으로 나타났으며, 보편적인 지지력계수 제안식들이 가정하고 있는 관련흐름법칙(associated flow-rule)이 적용된 경우(${\psi}={\phi}$)를 기준으로 비관련흐름법칙(nonassociated flow-rule)이 적용된 경우(${\psi}$ < ${\phi}$)의 상대적인 지지력 비율을 산출하였고, 일반적인 모래에 대한 관계식을 제안하였다. 원형기초의 형상계수는 연속기초의 평면변형률 조건의 고려 여부에 따라 크게 변하였으며, 평면변형률 조건을 고려하여 내부마찰각을 증가시킨 경우가 기존의 실험 결과와 유사한 경향을 나타내었다. 형상계수 제안식들의 경향이 차이를 나타내는 원인에 대하여 고찰하고 설계시 적용 방안을 제시하였다.

고혈압 환자의 삶의 질 측정도구 개발 (Development of Measurement Scale for the Quality of Life in Hypertensive Patients)

  • 김건엽;감신;이상원;박기수;채성철;천병렬
    • Journal of Preventive Medicine and Public Health
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    • 제38권1호
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    • pp.61-70
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    • 2005
  • Objectives : To develop a tool for multidimensional measurement of the quality of life, which was psychometrically sound, short, and easy to administer for patients with hypertension. Methods : A sample of 1,115 hypertensive patients aged 20 or above in Cheong-Song County was studied from June 1997 to October 1998. In the development of the instrumental stage, the authors first conceptualized the quality of life. Item generation, item reduction, and questionnaire formatting were followed. Item-level (item descriptive, missing%, item internal consistency, item discriminant validity) analysis, scale-level (scale descriptive, floor and ceiling effect) analysis, and other tests(Cronbach's alpha, inter-dimension correlations, factor analysis, clinical validity) were performed to evaluate the validity and reliability of the new measurement scale. After 1 year, responsiveness and confirmatory factor analysis were performed. Results : The results of both item-level and scale-level analyses were acceptable. An acceptable degree of internal consistency was observed for each of the dimensions (Cronbach's alpha was 0.60 or higher). Inter-dimension correlations were below 0.50 and the factor analysis result was the same as the intended dimension structure. Correlation coefficients between perceived health status, stress and dimensions were proven to be acceptable. The result of comparing dimensional score means among ADL and MMSE-K groups above 60 years was statistically significant(p<0.05). The result of confirmatory factor analysis concluded that the dimensional structure model was well fitted. However, the result of responsiveness test using sensitivity and specificity was unsatisfactory. Conclusions : The newly developed measurement scale is psychometrically reliable and valid instrument for measuring quality of life in hypertensive patients.

신뢰성 향상을 위한 설문문항 설계: 철도안전문화 설문자료 사례를 중심으로 (Designing Questionnaires for Better Reliable Survey: Case Study of Using Railway Safety Culture Survey Data)

  • 임광균;김시곤
    • 대한토목학회논문집
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    • 제34권6호
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    • pp.1837-1844
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    • 2014
  • 철도외의 다른 산업분야에서 안전문화 측정에 대한 연구가 활발히 진행된 것과 달리, 국내 철도분야의 안전문화 성숙에 대한 연구는 아주 초보적인 단계에 머물러 있다. 본 연구는 철도안전문화 평가의 신뢰성을 높이기 위해 설문문항 구성 시 어떻게 평가요인을 구성하고, 설문문항 그룹이 해당 요인을 얼마나 잘 대변하고 있는지, 그리고 그룹을 정의한 기준이 다른 공통 속성을 갖는지 여부를 분석하기 위해 내적 신뢰도 및 요인 분석을 실시하였다. 요인분석 결과 기존 5개에서 7개 요소로 도출되었고, 그에 따른 설문문항의 그룹화 및 요소의 이름이 재부여 되었다. 이는 문항간에 내제된 공통 속성을 잘 파악하는 것이 설문자와 피 설문자 간의 견해 차이를 줄이는 데 중요함을 의미한다. 또한 새로운 요인 분류에 대한 문항들의 내부 신뢰도 확인결과 여전히 이전과 비교하였을 때 높게 관측되어 그 분류가 적절함을 확인하였다. 본 연구는 철도안전문화 평가의 신뢰성을 높이는데 통계적인 방법을 활용하여 기존 설문조사 결과를 검증하고 어떻게 접근해야 하는지 다루고 있어 관련분야에서 많이 활용될 것으로 기대된다.

The Study of social factors toward Academic Satisfaction in E-Learning Education

  • Kim, Kyung-Woo
    • 한국컴퓨터정보학회논문지
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    • 제21권11호
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    • pp.135-139
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    • 2016
  • This paper investigates the empirical implications. The research question of this study is to verify the influences of psychological and environmental factors toward performance satisfaction and durability of learning in E-Learning University. For empirical verification, a survey was conducted targeting 500 students in E-learning Universities. The results show that actional environment on academic satisfaction in learning is the most important factor followed by physical environment, internal motivation, and academic burnout. The effect of psychological factors on learning persistence was important in the order of academic vision, internal motivation, actional environment and physical environment. The effect of academic satisfaction on learning durability proved to be statistically significant. The results suggest that actional environment should be considered with top priority to increase the academic satisfaction. learning satisfaction, academic vision, and academic satisfaction to enhance students' intention to continue studies are important. Academic burnout has a negative effect on both academic satisfaction and learning persistence, suggesting that this aspect should be properly addresses. The effects of student background variables in E-learning were explored.

소비자 정보 분석을 통한 Take-out 전문점의 마케팅 전략 사례연구 (A Case Study on the Marketing Strategy for a Take-Out Specialty Store through Analysis of Customer Informations)

  • 이소정;신서영;양일선;이명강
    • 한국식생활문화학회지
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    • 제21권2호
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    • pp.131-141
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    • 2006
  • The purpose of this research is to develop the management strategy for a take-out specialty sore on the basis of SWOT analysis which requires analysis of internal and external environmental informations. The survey was performed in order to gather the internal and external customer informations for a take-out specialty store. The questionnaires developed were distributed to customers (N=188) and employees (N=23) at 5 take-out specialty store branches from April 25, 2002 to April 29, 2002. The statistical data analysis was completed by SPSS WIN 10.0 for descriptive analysis, factor nalaysis, and Pearson's correlation. IPA(Importance-Performance Analysis) was applied in order to identify the critical management issues which would be explained with the organization's weakness or strength. SWOT analysis was performed through identifying the organizational strength and weakness as internal environment factors and external environmental opportunity and threat as uncontrollable external factors.

The role of diuretic hormones (DHs) and their receptors in Drosophila

  • Gahbien Lee;Heejin Jang;Yangkyun Oh
    • BMB Reports
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    • 제56권4호
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    • pp.209-215
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    • 2023
  • Maintaining internal homeostasis and regulating innate behaviors are essential for animal survival. In various animal species, a highly conserved neuroendocrine system integrates sensory inputs and regulates physiological responses to environmental and internal changes. Diuretic hormones 44 and 31, which are homologs of mammalian corticotropin-releasing factor (CRF) and calcitonin gene-related peptide (CGRP), respectively, control body fluid secretion in Drosophila. These neuropeptides and their receptors have multiple physiological roles, including the regulation of body-fluid secretion, sleep:wake cycle, internal nutrient-sensing, and CO2-dependent response. This review discusses the physiological and behavioral roles of DH44 and DH31 signaling pathways, consisting of neuroendocrine cells that secrete DH44 or DH31 peptides and their receptor-expressing organs. Further research is needed to understand the regulatory mechanisms of the behavioral processes mediated by these neuroendocrine systems.