• Title/Summary/Keyword: Internal Diffusion

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The Change of $SaO_2$, PFT and ABGA During the Bronchofiberscopy (기관지 내시경 검사에 따른 산소 포화도, 폐기능 및 동맥혈 가스의 변화)

  • Kim, Jong-Seon;Shin, Jeon-Eun;Kim, Tae-Hee;Chang, Jung-Hyun;Cheon, Seon-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.3
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    • pp.574-582
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    • 1998
  • Background: Bronchofiberscopy is a procedure with a chance of airway irritation and it may cause pathophysiologic changes of respiratory system. So we tried to evaluate the influence of bronchofibercopy on $O_2$ saturation, ABGA and PIT by patient's basal status and procedure type. Method: $O_2$ saturation was measured every 1 minute from the left index finger tip with percutaneous oximetry. ABGA was done before and right after the bronchofiberscopy and PIT was done before and within 10 minutes after the bronchofiberscopy. Results: The mean time for bronchofiberscopy procedure was 14.5mim and $SaO_2$ maximally fall to 89.0 below 8% of the baseline after mean time of 8.4min, which was recovered at the end of the procedure. $SaO_2$ change amount was 8.4 % on Non-$O_2$ supply group, which was lower compared to 6.4 % of the $O_2$-supply group without statistically significance. Biopsy Group and BAL group showed more $SaO_2$ fall than washing only group. The level of $PaO_2$ and FEV1 of the patient didn't influence significantly on $SaO_2$ fall during the procedure. ABGA taken before and after the bronchofiberscopy showed mild fall of $PaO_2$ and mild rise of $PaCO_2$. Whereas PFT showed decrease of FEV1(P<0.05) and increase of RV without changes in airway resistance and pulmonary diffusion capacity. Comparing before and after the bronchofiberscopy, the washing group showed no significant changes on PIT, while the biopsy group and the BAL group showed increase of RV & decrease of $FEV_1$ after the bronchofiberscopy. BAL group showed more changing tendency rather than biopsy group although not statistically significant. Conclusion: Bronchofiberscopy is considered as a relatively safe procedure, but it would be better to be done with $O_2$ supply especially in the patient with low $PaO_2$ and in the case of biopsy and BAL.

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The Influence of Fat-Free Mass to Maximum Exercise Performance in Patients with Chronic Obstructive Pulmonary Disease (만성폐쇄성폐질환에서 제지방량이 최대운동능력에 미치는 영향)

  • Mun, Yeung Chul;Park, Hye Jung;Shin, Kyeong Cheol;Chung, Jin Hong;Lee, Kwan Ho
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.4
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    • pp.346-354
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    • 2002
  • Background : Dyspnea and a limitation in exercise performance are important cause of disability in patients with chronic obstructive pulmonary disease(COPD). A depleted nutritional state is a common problem in patients with a severe degree of chronic airflow limitation. This study was carried out to assess the factors determining the maximum exercise capacity in patients with COPD. Methods : The resting pulmonary function, nutritional status, and maximum exercise performance was assessed in 83 stable patients with moderate to severe COPD. The nutritional status was evaluated by bioelectrical impedance analysis. Maximum exercise performance was evaluated by maximum oxygen uptake($VO_2max$). Results : Among the 83 patients, 59% were characterized by nutritional depletion. In the depleted group, a significantly lower peak expiratory flow rate(p<0.05), Kco(p<0.01) and maximum inspiratory pressure(p<0.05), but a significantly higher airway resistance(p<0.05) was observed. The maximum oxygen uptake and the peak oxygen pulse were lower in the depleted group. The $VO_2max$ correlated with some of the measures of the body composition : fat-free mass(FFM), fat mass(FM), body mass index(BMI), intracellular water index(ICW index), and pulmonary function : forced vital capacity(FVC), forced inspiratory vital capacity(FIVC), diffusion capacity(DLCO) : or maximum respiratory pressure : maximum inspiratory pressure(PImax), maximum expiratory pressure(PEmax). Stepwise regression analysis demonstrated that the FFM, DLCO and FIVC accounted for 68.8% of the variation in the $VO_2max$. Conclusion : The depletion of the FFM is significant factor for predicting the maximum exercise performance in patients with moderate to severe COPD.

Tropical Night (Nocturnal Thermal High) in the Mountainous Coastal City

  • Choi, Hyo
    • Journal of Environmental Science International
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    • v.13 no.11
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    • pp.965-985
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    • 2004
  • The investigation of driving mechanism for the formation of tropical night in the coastal region, defined as persistent high air temperature over than 25$^{\circ}C$ at night was carried out from August 14 through 15, 1995. Convective boundary layer (CBL) of a 1 km depth with big turbulent vertical diffusion coefficients is developed over the ground surface of the inland basin in the west of the mountain and near the top of the mountain, while a depth of thermal internal boundary layer (TIBL) like CBL shrunken by relatively cool sea breeze starting at 100 km off the eastern sea is less than 150 m from the coast along the eastern slope of the mountain. The TIBL extends up to the height of 1500 m parallel to upslope wind combined with valley wind and easterly sea breeze from the sea. As sensible heat flux convergences between the surface and lower atmosphere both at the top of mountain and the inland coast are much greater than on the coastal sea, sensible heat flux should be accumulated inside both the TIBL and the CBL near the mountain top and then, accumulated sensible heat flux under the influence of sea breeze circulation combined with easterly sea breeze from sea to inland and uplifted valley wind from inland to the mountain top returning down toward the eastern coastal sea surface should be transported into the coast, resulting in high air temperatures near the coastal inland. Under nighttime cooling of ground surface after sunset, mountain wind causes the daytime existed westerly wind to be an intensified westerly downslope wind and land breeze further induces it to be strong offshore wind. No sensible heat flux divergence or very small flux divergence occurs in the coast, but the flux divergences are much greater on the top of the mountain and along its eastern slope than on the coastal inland and sea surfaces. Thus, less cooling down of the coastal surface than the mountain surface and sensible heat transfer from warm pool over the coast into the coastal surface produce nocturnal high air temperature on the coastal inland surfaces, which is not much changed from daytime ones, resulting in the persistence of tropical night (nocturnal thermal high) until the early in the morning.

Rhizospheric fungi of Panax notoginseng: diversity and antagonism to host phytopathogens

  • Miao, Cui-Ping;Mi, Qi-Li;Qiao, Xin-Guo;Zheng, You-Kun;Chen, You-Wei;Xu, Li-Hua;Guan, Hui-Lin;Zhao, Li-Xing
    • Journal of Ginseng Research
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    • v.40 no.2
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    • pp.127-134
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    • 2016
  • Background: Rhizospheric fungi play an essential role in the plantesoil ecosystem, affecting plant growth and health. In this study, we evaluated the fungal diversity in the rhizosphere soil of 2-yr-old healthy Panax notoginseng cultivated in Wenshan, China. Methods: Culture-independent Illumina MiSeq and culture-dependent techniques, combining molecular and morphological characteristics, were used to analyze the rhizospheric fungal diversity. A diffusion test was used to challenge the phytopathogens of P. notoginseng. Results: A total of 16,130 paired-end reads of the nuclear ribosomal internal transcribed spacer 2 were generated and clustered into 860 operational taxonomic units at 97% sequence similarity. All the operational taxonomic units were assigned to five phyla and 79 genera. Zygomycota (46.2%) and Ascomycota (37.8%) were the dominant taxa; Mortierella and unclassified Mortierellales accounted for a large proportion (44.9%) at genus level. The relative abundance of Fusarium and Phoma sequenceswas high, accounting for 12.9% and 5.5%, respectively. In total,113 fungal isolates were isolated from rhizosphere soil. They were assigned to five classes, eight orders (except for an Incertae sedis), 26 genera, and 43 species based on morphological characteristics and phylogenetic analysis of the internal transcribed spacer. Fusarium was the most isolated genus with six species (24 isolates, 21.2%). The abundance of Phoma was also relatively high (8.0%). Thirteen isolates displayed antimicrobial activity against at least one test fungus. Conclusion: Our results suggest that diverse fungi including potential pathogenic ones exist in the rhizosphere soil of 2-yr-old P. notoginseng and that antagonistic isolates may be useful for biological control of pathogens.

Effect of Containing Promoter on SCR Catalysts (SCR 촉매에 포함된 조촉매 영향)

  • Seo, Choong-Kil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.9
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    • pp.474-481
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    • 2018
  • The policy-making and technological development of eco-friendly automobiles designed to increase their supply is ongoing, but the internal combustion engine still accounts for approximately 95% of automobiles in use. To meet the stricter emission regulations of internal combustion engines based on fossil fuels, the proportion of after-treatments for vehicles and (ocean going) vessels is increasing continuously. As diesel engines have high power and good fuel economy in addition to less CO2 emissions, their market share is increasing not only in commercial vehicles, but also in passenger cars. Because of the characteristics of the diesel combustion, however, NOx is generated in localized high-temperature combustion regions, and particulates are formed in the zones of diffusion combustion. LNT and urea-SCR catalysts have been developed for the after-treatment of exhaust gas to reduce NOx in diesel vehicles. This study examined the effect of a containing promoter on SCR catalysts to cope with the severe exhaust gas regulation. The de-NOx performance of the Mn-SCR catalyst was the best, and the de-NOx performance was improved as the ion exchange rate between Mn ion and Zeolyst was good and the activation energy was low. The de-NOx performance of the 7Cu-15Ba/78Zeoyst catalyst was 32% at $200^{\circ}C$ and 30% at $500^{\circ}C$, and showed the highest performance. The NOx storage material of BaO loaded as a promoter was well dispersed in the Cu-SCR catalyst and the additional de-NOx performance of BaO was affected by the reduction reaction of the Cu-SCR catalyst. Among the three catalysts, the 7Cu-15Ba/Zeolyst SCR catalyst was resistant to thermal degradation. The same type of CuO due to thermal degradation migrates and agglomerates because BaO reduces the agglomeration of the main catalyst CuO particles.

Fire Resistance Performance of High Strength Concrete with 4 Deformation Factors (4변형 인자에 의한 고강도콘크리트의 내화성능 평가)

  • Lee, Tae Gyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.16 no.5
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    • pp.112-120
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    • 2012
  • A numerical model considering the internal vaporization and the creep effect, in the form of a analytical program, for tracing the behavior of high strength concrete(HSC) members exposed to fire is presented. The two stages, i.e., spalling procedure and fire resistance time, associated with the thermal, moisture flow, creep and structural analysis, for the prediction of fire resistance behavior are explained. The use of the analytical program for tracing the response of HSC member from the initial pre-loading stage to collapse, due to fire, is demonstrated. Moisture evaporates, when concrete is exposed to fire, not only at concrete surface but also at inside the concrete to adjust the equilibrium and transfer properties of moisture. Finite element method is employed to facilitate the moisture diffusion analysis for any position of member, so that the prediction method of the moisture distribution inside the concrete members at fire is developed. The validity of the numerical model used in this program is established by comparing the predictions from this program with results from others fire resistance tests. The analytical program can be used to predict the fire resistance of HSC members for any value of the significant parameters, such as load, sectional dimensions, member length, and concrete strength.

A Micro-Mechanics Based Corrosion Model for the Prediction of Service Life in Reinforced Concrete Structures

  • Song, Ha-Won;Kim, Ho-Jin;Kim, Tae-Hwan;Byun, Keun-Joo;Lee, Seung-Hoon
    • Corrosion Science and Technology
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    • v.4 no.3
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    • pp.100-107
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    • 2005
  • Reinforcing steel bars in reinforced concrete structures are protected from corrosion by passive film on the steel surface inside concrete with high alkalinity. However, when the passive film breaks down due to chloride ion ingressed into the RC structures, a corrosion initiates at the surface of steel bars. Then, internal pressure by volume expansion of corrosion products in reinforcing bars induces cracking and spalling of cover concrete, which reduces not only durability performance but also structural performance in RC structures. In this paper, a service life prediction of RC structures is carried out by using a micro-mechanics based corrosion model. The corrosion model is composed of a chloride penetration model to evaluate the initiation of corrosion and an electric corrosion cell model and an oxygen diffusion model to evaluate the rate and the accumulated amounts of corrosion. Then, a corrosion cracking model is combined to the models to evaluate critical amount of corrosion product for initiation cracking in cover concrete. By implementing the models into a finite element analysis program, a time and space dependent corrosion analysis and a service life prediction of RC structures due to chloride attack are simulated and the results of the analysis are compared with test results. The effect of crack width on the corrosion and the service life of the RC structures are analyzed and discussed.

Effects of the Combination Herbal Extract on Working Memory and White Matter Integrity in Healthy Individuals with Subjective Memory Complaints : A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

  • Kwon, Oran;Lee, Sunho;Ban, Soonhyun;Im, Jooyeon J.;Lee, Doo Suk;Lee, Eun Hee;Kim, Joohee;Lim, Soo Mee;Lee, Sang Gon;Kang, Ilhyang;Kim, Kyung-Hee;Yoon, Sujung;Lee, Sun Hea
    • Korean Journal of Biological Psychiatry
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    • v.22 no.2
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    • pp.63-77
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    • 2015
  • Objectives The combination extract of four kinds of herbs, Gastrodia elata, Liriope platyphylla, Dimocarpus longan, and Salvia miltiorrhiza, has shown to have memory improving effects in mice. The aim of this study was to investigate the efficacy and safety of the herbal mixture for improving working memory as well as microstructural changes in white matter integrity in individuals with subjective memory complaints. Methods Seventy-five individuals with subjective memory complaints were assigned to receive either placebo (n = 15) or herbal mixture (low-dose group, n = 30 and high-dose group, n = 30) supplementation in an 8-week, randomized, double-blind, placebo-controlled clinical trial. Changes in working memory performance and fractional anisotropy (FA) values reflecting white matter integrity from baseline to 8-week endpoint were assessed. Results The herbal mixture group showed an increase in working memory performance compared to the placebo group (p for interaction = 0.001). In addition, the herbal mixture group showed an increase in FA values in the temporo-parietal regions (corrected p < 0.05), which are crucially involved in working memory function and are among the most affected regions in patients with cognitive impairments. Conclusions Findings from this study indicate that the herbal mixture may be a promising therapeutic option for individuals with subjective memory complaints.

Influence of piston bowl geometry on the in-cylinder flow of HCCI Engine (HCCI 엔진의 실린더 내 유동에 대한 피스톤 보울 형상의 영향)

  • Nam, Seung Man;Lee, Kye Bock
    • Journal of Energy Engineering
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    • v.22 no.4
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    • pp.399-405
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    • 2013
  • The gas motion inside the engine cylinder plays a very important role in determining the thermal efficiency of an internal combustion engine. A precise information of in-cylinder three dimensional complex gas motion is crucial in optimizing engine design. Homogeneous charge compression ignition (HCCI) engine is a combustion concept, which is a hybrid between Otto and Diesel engine. The turbulent diffusion leads to increased rates of momentum, heat and mass transfer. The in-cylinder turbulence flow was found to affect the present HCCI combustion mainly through its influence on the wall heat transfer. This study investigates the effect of piston geometry shape on the turbulent flow characteristics of in-cylinder from the numerical analysis using the LES model and the results obtained can offer guidelines of the combustion geometries for better combustion process and engine performance.

Full Parametric Impedance Analysis of Photoelectrochemical Cells: Case of a TiO2 Photoanode

  • Nguyen, Hung Tai;Tran, Thi Lan;Nguyen, Dang Thanh;Shin, Eui-Chol;Kang, Soon-Hyung;Lee, Jong-Sook
    • Journal of the Korean Ceramic Society
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    • v.55 no.3
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    • pp.244-260
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    • 2018
  • Issues in the electrical characterization of semiconducting photoanodes in a photoelectrochemical (PEC) cell, such as the cell geometry dependence, scan rate dependence in DC measurements, and the frequency dependence in AC measurements, are addressed, using the example of a $TiO_2$ photoanode. Contrary to conventional constant phase element (CPE) modeling, the capacitive behavior associated with Mott-Schottky (MS) response was successfully modeled by a Havriliak-Negami (HN) capacitance function-which allowed the determination of frequency-independent Schottky capacitance parameters to be explained by a trapping mechanism. Additional polarization can be successfully described by the parallel connection of a Bisquert transmission line (TL) model for the diffusion-recombination process in the nanostructured $TiO_2$ electrode. Instead of shunt CPEs generally employed for the non-ideal TL feature, TL models with ideal shunt capacitors can describe the experimental data in the presence of an infinite-length Warburg element as internal interfacial impedance - a characteristic suggested to be a generic feature of many electrochemical cells. Fully parametrized impedance spectra finally allow in-depth physicochemical interpretations.