• Archives of Plastic Surgery
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• 제36권4호
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• pp.380-384
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• 2009

Purpose: Autologous vessels remain the gold standard for vascular grafts in microanastomoses. However, they are sometimes unavailable and have a limited long - term patency. Synthetic vessels have high success rates in large - diameter reconstructions but failed when used as small - diameter grafts due to graft occlusion. It has been proved that endothelial cell seeding improves prosthesis performance and long - term patency. Among polyurethane, PET and ePTFE, polyurethane has the best affinity to endothelial cells and mechanical properties closest to human vessels. We examined the ability of endothelial cells to attach to a polyurethane graft manufactured by the electrospinning method. Methods: Endothelial cells, which were cultured from porcine internal jugular veins, were attached to polyurethane grafts with an internal diameter of 3 mm. The same cells were attached to allogeneic decellularized porcine internal carotid artery grafts as controls. Both of the 10 mm - long grafts were exposed to endothelial cells in a well for 1 hour. Each well contained $2{\times}10^5$ endothelial cells. The graft materials were rotated through 90 degrees every 15 minutes in order to minimize the effect of gravity. The extent of cell attachment was examined with the MTT assay. Results: The MTT assay showed good incorporation of endothelial cells into both grafts. For the evaluation of affinity, the number of attached cells was counted at 10 fields of microscopic examination with ${\times}40$ magnification. Endothelial cells adhered more to polyurethane grafts (mean, $127.4{\pm}6.2cells$) compared to porcine artery grafts (mean $45.8{\pm}5.1cells$)(p<0.05,Mann - Whitney test). Conclusion: In this study, we attached porcine endothelial cells to polyurethane grafts, manufactured by electrospinning. The grafts exhibited a better affinity to endothelial cells than allogeneic decellularized porcine internal carotid artery grafts. It is suggested that the time required for endothelial cells to attach to decellulized artery grafts may be longer than that which is required for attachment to polyurethane grafts.

• Journal of Chest Surgery
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• 제32권10호
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• pp.883-890
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• 1999

Long term patency of arterial graft has been better than venous graft and redo coronary artery bypass grafting has been increasing, therefore, there has been an increasing need for alternative arterial grafts except internal thoracic artery(ITA). Material and Method: Right gastroepiploic arteries(RGEA) were harvested from 100 patients who had received gastrectomy for gastric cancer or ulcer. ITAs were obtained from 10 patients undergoing coronary artery bypass grafting. The length of RGEA was measured from the pyloric ring. Items of the morphometric and histologic study at the pyloric ring and sites of the 10cm and 20cm RGEA from the pyloric ring were luminal diameter, intimal thickness, medial thickness, wall thickness, degree of intimal hyperplasia, intimal thickness, medial thickness, wall thickness, degree of intimal hyperplasia, intimal thickness index, medial thickness index, and the number of discontinuities of the internal elastic lamina. Similar items were applied to the proximal site of ITAs. Result: The length of RGEA was 23${\pm}$2.7cm(range 17∼31cm). Comparing the 20cm RGEA with ITA, intimal thickness, medial thickness, wall thickness, and degree of intimal hyperplasia did not show any difference(p>0.05). However, 20cm RGEA was greater than ITA at the luminal diameter, intimal thickness index, and the number thickness and wall thickness in each site of the RGEA(pyloric ring, 10cm, 20cm) decreased from the pyloric ring to the distal sites(p<0.05). The degree of intimal hyperplasia and the number of discontinuities of the internal elastic lamina did not show any difference between the pyloric ring and 10cm, however, those of 20cm were smaller than these sites(p<0.05). RGEA had more number of discontinuities of the internal elastic lamina and rich smooth muscle cells in the media than ITA. Conclusion: The length and diameter of RGEA is good enough to reach most of the coronary arteries. Moreover, long term patency of RGEA may be improved, if anastomosed in the distal site.

• 대한한방내과학회지
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• 제33권4호
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• pp.572-586
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• 2012

Objectives : This study was designed to investigate the effects of Sasim-tang (SST) on proinflammatory cytokine production in a photothrombotic ischemia mouse model. Methods : Photothrombotic ischemia was induced in stereotactically held male Balb/c mice using rose bengal (10 mg/kg) and cold light. The target of photothrombotic ischemic lesion was 1 mm anterior to bregma and 3 mm lateral to midline with 2 mm in diameter, which are decreased by oral administration of SST. Results : SST protected ischemic death of brain cells through inhibition of pro-inflammatory cytokines production and catalytic activation of caspase-3 protease in photothrombotic ischemia mouse model. Conclusions : The results of this study suggest that SST can have protective effects on brain cell damage in a photothrombotic ischemia mouse model.

• Journal of Mechanical Science and Technology
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• 제17권11호
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• pp.1739-1745
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• 2003

The boiling heat transfer characteristics of two-phase closed thermosyphons with internal grooves are studied experimentally and a simple mathematical model is developed to predict the performance of such thermosyphons. The study focuses on the boiling heat transfer characteristics of a two-phase closed thermosyphons with copper tubes having 50, 60, 70, 80, 90 internal grooves. A two-phase closed thermosyphon with plain copper tube having the same inner and outer diameter as those of grooved tube is also tested for comparison. Methanol is used as working fluid. The effects of the number of grooves, the operating temperature, the heat flux are investigated experimentally. From these experimental results, a simple mathematical model is developed. In the present model, boiling of liquid pool in the evaporator is considered for the heat transfer mechanism of the thermosyphon. And also the effects of the number of grooves, the operating temperature, the heat flux are brought into consideration. A good agreement between the boiling heat transfer coefficient of the thermosyphon estimated from experimental results and the predictions from the present mathematical model is obtained. The experimental results show that the number of grooves and the amount of the working fluid are very important factors for the operation of thermosyphons. The two-phase closed thermosyphon with copper tubes having 60 internal grooves shows the best boiling heat transfer performance.

• 한국기계가공학회지
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• 제14권1호
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• pp.123-129
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• 2015

In general, recent critical studies of five-axis machine have tended to center on the question of effective machining to realize complex shape parts. However, the hydrostatic bearing and journal bearing, both of which are involved in the complex process of dividing the processing of internal precision-shape machining, must be optimized. Although the angle head is designed to machine the internal shape as it approaches the inner diameter of the work piece, research on the angle head in five-axis machining has received only minimal attention in domestic industries. In this study, an angle head which is optimized for effective internal shape machining is developed. In pursuit of this purpose, 3D and 2D designs of the angle head for five-axis machining are devised. Reliability is secured through static performance tests and machining accuracy evaluations of the angle head in keeping with the machining accuracy standard of 0.2mm for hydrostatic bearings.

• 한국기계가공학회지
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• 제16권4호
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• pp.147-152
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• 2017

In the present study, we used a loop thermosyphon heat exchanger consisting of condensers with internal fins and external plate fins which are 480 mm wide, 68 mm long, and 1,000 mm high. The heat transfer pipes in the heat exchanger were 15 mm in diameter and 1,000 mm in length, and 98 heat transfer pipes were installed in the heat exchanger. According to the experimental results, as the spaces between the internal discontinuous pins decreased, the frequency of pressure drops increased and changes in temperature at the outlet of the condenser were shown to be a little smaller. Therefore, we can see that as the spaces between internal discontinuous pins decreased, the heat transfer performance increased. For the loop heat pipe heat exchanger consisting of a condenser with internal and plate fins, as the temperature of the air flowing into the condenser increased, the condensation heat transfer rate also increased, and as the condenser refrigerant inflow temperature increased, the condensation heat transfer rate increased as well.

• Tuberculosis and Respiratory Diseases
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• 제43권3호
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• pp.455-460
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• 1996

폐기포는 폐 내부에 공기를 포함하는 공간으로 보통 1cm 이상의 크기와 2mm이하의 모발선 모양의 기포벽을 갖는다. 자연경과상 지속적으로 약화되는 양상을 보이고 자연소실 또는 호전되는 경우는 매우 드문 것으로 알려져 있다. 저자들은 임신중 발생한 속립성 결핵 환자에서 성인형 호흡곤란 증후군의 경과 후 발생한 다발성 폐기포가 자연소실된 1예를 관찰하였기에 보고하는 바이다.

• Smart Structures and Systems
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• 제17권1호
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• pp.31-43
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• 2016

Applications of ultrasonic tomography to concrete structures have been reported for many years. However, practical and effective application of this tool for nondestructive assessment of internal concrete condition is hampered by time consuming transducer coupling that limits the amount of ultrasonic data that can be collected. This research aims to deploy recent developments in air-coupled ultrasonic measurements of solids, described in Part 1 of this paper set, to concrete in order to image internal inclusions. Ultrasonic signals are collected from concrete samples using a fully air-coupled (contactless) test configuration. These air coupled data are compared to those collected using partial semi-contact and full-contact test configurations. Two samples are considered: a 150 mm diameter cylinder with an internal circular void and a prism with $300mm{\times}300mm$ square cross-section that contains internal damaged regions and embedded reinforcement. The heterogeneous nature of concrete material structure complicates the application and interpretation of ultrasonic measurements and imaging. Volumetric inclusions within the concrete specimens are identified in the constructed velocity tomograms, but wave scattering at internal interfaces of the concrete disrupts the images. This disruption reduces defect detection accuracy as compared with tomograms built up of data collected from homogeneous solid samples (PVC) that are described in Part 1 of this paper set. Semi-contact measurements provide some improvement in accuracy through higher signal-to-noise ratio while still allowing for reasonably rapid data collection.

• Nuclear Engineering and Technology
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• 제42권1호
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• pp.109-114
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• 2010

Bioassay data analysis software (BiDAS-2007) has been developed by KAERI, which adds several new functions to its previous version. New functions of the BiDAS-2007 computer code enable the user not only to do a simultaneous analysis by using two or more types of bioassay for the best internal dose evaluation, but also to do a continual internal dose evaluation from a change of the internal exposure conditions such as an intake type (acute, chronic), an intake pathway (inhalation, ingestion), an absorption type (Type F, M, S), and a particle size (AMAD, activity median aerodynamic diameter), and also to estimate the intakes in various conditions of an internal exposure at a time. The values calculated by the BiDAS-2007 code are consistent and in good agreement with those values by IMIE-2004 code by Berkovski and IMBA code by Birchall. The BiDAS-2007 computer code is very useful and user-friendly to estimate the radionuclide intakes and committed effective doses of a radiation worker.

• 한국동물위생학회지
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• 제46권4호
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• pp.349-355
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• 2023

A 7-year-old castrated male Pomeranian dog presented with severe goose honking cough and dyspnea. Thoracic radiographs revealed a narrowed tracheal diameter at the thoracic inlet, classified as tracheal collapse grade 4. Despite medical treatment, the dog's life-threatening airway obstruction did not improve. Subsequently, tracheal stent placement resulted in a significant improvement in respiratory condition, with no recurrence of symptoms observed during the 4-month period, except for coughing induced by excitement and anxiety. However, the patient presented with a one-week history of productive cough, exercise intolerance, and loss of appetite. Radiographs and computed tomography scans revealed torsion of the left cranial lung lobe. The patient underwent affected lung lobectomy, which involved the removal of the necrotized cranial portion and heavily congested caudal portion. Unfortunately, the patient did not recover and eventually passed away. Histopathological examination of the resected lung tissue confirmed coagulative necrosis and marked peribronchiolar edema, consistent with lung lobe torsion.