• Asian Journal of Atmospheric Environment
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• 제8권3호
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• pp.162-174
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• 2014

An abnormal decrease in ozonesonde sensor signal occurred during air-pollution study campaigns in November 2011 and March 2012 in Mexico City Metropolitan Area (MCMA). Sharp drops in sensor signal around 5 km above sea level and above were observed in November 2011, and a reduction of signal over a broad range of altitude was observed in the convective boundary layer in March 2012. Circumstantial evidence indicated that $SO_2$ gas interfered with the electrochemical concentration cell (ECC) ozone sensors in the ozonesonde and that this interference was the cause of the reduced sensor signal output. The sharp drops in November 2011 were attributed to the $SO_2$ plume from Popocat$\acute{e}$petl volcano southeast of MCMA. Experiments on the response of the ECC sensor to representative atmospheric trace gases showed that only $SO_2$ could cause the observed abrupt drops in sensor signal. The vertical profile of the plume reproduced by a Lagrangian particle diffusion simulation supported this finding. A near-ground reduction in the sensor signal in March 2012 was attributed to an $SO_2$ plume from the Tula industrial complex north-west of MCMA. Before and at the time of ozonesonde launch, intermittent high $SO_2$ concentrations were recorded at ground-level monitoring stations north of MCMA. The difference between the $O_3$ concentration measured by the ozonesonde and that recorded by a UV-based $O_3$ monitor was consistent with the $SO_2$ concentration recorded by a UV-based monitor on the ground. The vertical profiles of the plumes estimated by Lagrangian particle diffusion simulation agreed fairly well with the observed profile. Statistical analysis of the wind field in MCMA revealed that the effect Popocat$\acute{e}$petl was most likely to have occurred from June to October, whereas the effect of the industries north of MCMA, including the Tula complex, was predicted to occur throughout the year.

• Journal of Korean Neurosurgical Society
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• 제58권2호
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• pp.150-154
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• 2015

Cerebral venous sinus thrombosis (CVST) following a closed head injury in pediatric patients is a rare condition, and an early spontaneous recanalization of this condition is extremely rare. A 10-year-old boy was admitted with a mild, intermittent headache and nausea five days after a bicycle accident. The brain computed tomography showed an epidural hematoma at the right occipital area with pneumocephalus due to a fracture of the occipital skull bone. The brain magnetic resonance imaging and the magnetic resonance venography demonstrated a flow signal loss from the right sigmoid sinus to the right jugular vein. The diagnosis was sigmoid sinus thrombosis, so close observations were selected as a treatment for the patient because of his gradually improving symptoms; however, he complained of vomiting 14 days the after conservative treatment. The patient was readmitted for a further examination of his symptoms. The laboratory and the gastroenterological examinations were normal. Due to concern regarding the worsening of the sigmoid sinus thrombosis, the brain magnetic resonance venography was rechecked and it revealed the recanalization of the venous flow in the sigmoid sinus and in the jugular vein.

• Journal of Positioning, Navigation, and Timing
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• 제9권3호
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• pp.237-248
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• 2020

GNSS has been evolving dramatically in recent years. There are currently 6 GNSS (4 GNSS, AND 2 RNSS) constellations, which are GPS (USA), GLONASS (Russia), BeiDou (China), Galileo (EU), QZSS (Japan), and IRNSS (India). The Number of navigation satellites is expected to be over 150 by 2020. As the number of both constellations and satellites used for the improvement of positioning performance, high accuracy, and robustness of precise positioning is more promising. However, a large amount of the correction messages is required to support the augmentation system for the available satellites of all the constellations. Since bandwidth for the correction messages is generally limited, sending or scheduling the correction messages might be a critical issue in the near future. In this study, we analyze the relationship between the size of the bandwidth and Real-Time Kinematics (RTK) performance. Multiple Signal Messages (MSM), the only Radio Technical Commission for Maritimes (RTCM) message that supports multi-constellation GNSS, has been used for this assessment. Instead of the conventional method that broadcasts all the messages at the same time, we assign the MSM broadcasting interval for each constellation in 5 seconds. An open sky static and dynamic test for this study was conducted on the roof of Sejong University. Our results show that the RTK fixed position accuracy is not affected by the 5-second interval corrections, but the ambiguity fixing rate is degraded for poor DOP cases when RTK correction are transmitted intermittently.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2006년 창립20주년기념 정기학술대회 및 국제워크샵
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• pp.327-330
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• 2006

With the increasing requirements for the survey and development of the ocean, the demands on the of AUV(Autonomous Underwater Vehicle) technologies have been increased. Reconstruction and replay of the AUV motion on the basis of the data stored during the execution of mission, can help the development of control strategies for AUVs such as mission planning and control algorithms. While an AUV cruises for her mission, her attitude and position data are is recorded. The data can be used for visualization of the motion in off-line. However, because most of the position data gathered from acoustic sensors have long time-interval and include intermittent faulty signal, the replayed motion by the graphic simulator can not demonstrate the motion as a smooth movie. In this paper, interpolation methods are surveyed to reconstruct the AUV position data. Then, an efficient 3D visualization method for AUV motion using the interpolation method is proposed. Simulation results arc also included to verify the proposed method.

• 설비공학논문집
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• 제9권4호
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• pp.472-483
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• 1997

An experimental facility consisting of two $3{\times}4.4{\times}3.8m$ rooms identical in construction is built. Each room has a control system and storage tank supplying hot water to the radiant floor heating system. The facility enables simultaneous comparision of two different control stratigies each implemented in a separate room. The operating performance of three kinds of flow control scheme is tested and compared in this study : (i) conventional on-off control based on feedback from room air temperature (ii) TPSC(two parameter switching control) (iii) TPOC(two parameter on-off control). Results show that TPSC and TPOC using room air and surface temperature sequentially as feedback signal to control hot water supply is the better temperature regulation scheme than conventional control based on feedback from only room air temperature. They are good candidates for the room with radiant floor heating system under continuous and intermittent heating mode.

• Journal of Microbiology and Biotechnology
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• 제9권6호
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• pp.811-819
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• 1999

The ${\beta}-CGTase$ gene of alkalophilic Bacillus firmus var. alkalophilus was cloned into E. coli using $pZErO^{TM}-2$ as a vector. The cloned gene encoded a total of 710 amino acid residues consisting of 674 amino acids of the matured protein and 36 amino acids of the signal peptide, including 20 amino acids from the lacZ gene in the vector. Although the cloned ${\beta}-CGTase$ gene did not contain the promoter and start codons, it was expressed by the lac promoter and lacZ start codon in the $pZErO^{TM}$ vector. A comparison was made with the amino acid sequence and ten other CGTases from Bacillus sp. Also, ten highly conserved regions, which are important amino acid residues in catalysis of CGTase, were identified. The lac promoter used for expression of the ${\beta}-CGTase$ gene was induced constitutively in recombinant E. coli even without IPTG possibly because of a lack of the lacI gene in both host and vector, repressing the lacZ gene in the lac operon. Its expression was catabolically repressed by glucose, however, its repression was reduced by soluble starch, mainly because of the extremely high increase of the cAMP level. ${\beta}-CGTase$ can be overproduced in the recombinant E. coli by maintaining intracellular cAMP levels mostly through the intermittent feeding of glucose during cultivation.

• 수산해양기술연구
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• 제21권1호
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• pp.1-6
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• 1985

북해의 Norway 근해에 있는 외해의 한 점과 Bergen권 입구에 있는 Skossvassen 내만에서 수중환경소음을 측정하여 그 음향 spectrum을 분석한 결과를 요약하면 다음과 같다. 1) Norway 근해에서 측정된 수중환경소음의 주된 주파수대는 500Hz 이하의 저주파였다. 2) Skossvassen 내만에서 측정된 수중환경소음은 10m층에서의 음압이 25m와 50m층에서의 음압보다 약 7dB정도 높았다. 이것은 주된 소음원이 관측점부근을 통항하는 선박이나 육지의 영향을 많이 받는 표층에 있다는 것을 나타낸다. 3) Norway 근해의 외해에서 측정된 수중환경소음은 각 층에서 측정된 spectrum의 형태와 음압준위가 비슷한 현상을 나타내고 있어서 원거리에 있는 소음원의 영향을 많이 받기 때문인 것으로 생각된다.

• 대한전자공학회논문지SD
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• 제47권2호
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• pp.68-76
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• 2010

최근 터치스크린 기술은 인간이 컴퓨터와 대화할 수 있는 주요 도구로서 급진적인 발전을 이루고 있다. 이 사용자 친화적인 인터페이스는 휴대폰에 이어 데스크탑, TV와 같은 대형스크린 시장까지 확산되어가고 있지만 기존의 저항막방식, 정전용량방식, 초음파방식 등은 기술 및 비용문제로 인하여 중 대형스크린에 적용하기 힘들다. 따라서 본 논문에서는 적외선과 라인스캔 이미지센서를 이용하여 간단하고 저렴한 비용으로 중 대형스크린에 적용할 수 있는 광학 영상 터치스크린 솔루션을 소개하고 이 기술이 갖는 문제점과 해결방안을 제시한다. 멀티 포인트를 추출하기 위한 주요 알고리즘은 범용프로세서를 이용하여 구현 시 약 34ms(29fps)가 소요되었으며 이는 휴먼인터페이스 디바이스로 사용되기에는 불충분하였다. 이를 해결하기 위하여 본 논문에서는 신호처리 및 좌표추출연산을 위한 하드웨어를 설계하여 성능을 향상시키고 광학 영상 터치스크린이 갖는 문제점을 소프트웨어에서 효율적으로 처리할 수 있도록 하였다. 설계한 터치스크린 컨트롤러의 PSM(Power Saving Mode)은 1.8Wh의 적외선 소비에너지를 0.0072Wh 까지 개선하였으며 60인치 대형스크린에서 2개의 실제 좌표를 200fps 속도로 연산해낸다.

• Biomolecules & Therapeutics
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• 제25권3호
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• pp.239-248
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• 2017

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which is commonly explained by steric hindrance caused by the ${\beta}$-arrestins that are translocated to the activated receptors, molecular mechanisms involved in the acute tolerance of GPCRs remain unclear. Our studies with several GPCRs and related mutants showed that the acute tolerance of GPCRs could occur independently of agonist-induced ${\beta}$-arrestin translocation. A series of co-immunoprecipitation experiments revealed a correlation between receptor tolerance and interactions among receptors, ${\beta}$-arrestin2, and $G{\beta}{\gamma}$. $G{\beta}{\gamma}$ displayed a stable interaction with receptors and ${\beta}$-arrestin2 in cells expressing GPCRs that were prone to undergo tolerance compared to the GPCRs that were resistant to acute tolerance. Strengthening the interaction between $G{\beta}{\gamma}$ and ${\beta}$-arrestin rendered the GPCRs to acquire the tendency of acute tolerance. Overall, stable interaction between the receptor and $G{\beta}{\gamma}$ complex is required for the formation of a complex with ${\beta}$-arrestin, and determines the potential of a particular GPCR to undergo acute tolerance. Rather than turning off the signal, ${\beta}$-arrestins seem to contribute on continuous signaling when they are in the context of complex with receptor and $G{\beta}{\gamma}$.

• Investigative Magnetic Resonance Imaging
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• 제2권1호
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• pp.14-30
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• 1998

망간은 체내 필수원소의 하나이며 주로 간과 뇌의 기저핵게 축적되며 간을 통하여 배설된다. 망간은 체내 대사가 매우 빠르기 때문에 직업적 망간 폭로를 측정하는데 어려움이 있다. 특히 용접공과 같이 망간 폭로가 간헐적이거나 불규칙한 경우에는 혈중 및 요중 망간과 같은 기존 생체폭로지표로는 장기간에 걸친 폭로량을 정확하게 반영하기 힘들다. 뇌자기공명영상이 대두됨에 따랄 뇌내에 축적된 망간을 영상으로 확인하는 것이 가능하게 되었다. 초기에는 만성간부전 및 장기간에 걸친 정맥영양주입환자 등에서 뇌기저부의 고신호간도 소견이 보고되었다. 망간은 상자성 물질로 뇌자기공명영상에서 T1 이완시간을 단축시켜 T1 강조영상에서 고신호강도를 나타난다. 망간축적에 따른 고신호강도는 주로 담창구, 흑질, 피간 및 뇌하수체 등에서 나타난다. 저자들은 최근까지 국내 및 국외에서 직업적 및 비직업적으로 망간에 폭로된 사람에서 보고된 뇌자기공명영상소견을 수집하여 분석하였다. 우선 T1강조영상에서 관찰되는 고신호 강도와 연령, 성별, 직업적 망간 폭로 및 신경학적 이상 유무간의 관계를 분석하였다. 생물학적 폭로지표와 고신호강도간의 관계도 분석하였다. 고신호강도와 뇌내 망간축적, 신경세포손상 및 신경학적 이상간의 관계에 대한 문헌들을 분석하였다. T1강조영상에서 나타나는 고신호강도는 뇌내 망간축적 정도를 반영한다. 이러한 관계를 이용하여 신호강도를 분석하므로써 뇌내 망간축적 정도를 추정할수 있다. 뇌내 망간축적은 기저핵의 신경세포손상을 초래한다. 그러나 신경학적 이상은 비교적 단기간에 걸친 망간 축적과는 무관하게 보인다. 이는 신경학적 이상소견은 마간의 누적축적량과 관련되어 있기 때문인것으로 추정된다. 뇌자기 공명영사에서 관찰되는 고신호강도 소견은 표적 장기의 망간적 축적량을 반영하는데는 충분하지 못한 것으로 보인다. 따라서이러한 놔자기공명영상의 특성 및 비용-효과적인 측면을 고려할 대 망간폭로집안에서의 망간폭로정도를 추정하기 위하여 놔자기공명영상을 사용하는 것은 바람직하지 않다고 보인다. 그러나 망간과 관련된 건강장해가 의심되는 파킨슨증 환자에서 망간폭로를 확인 및 추정하는 데에는 매우 유용하게 활용할 수 있다.