Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors |
Min, Chengchun
(Pharmacology Laboratory, College of Pharmacy, Chonnam National University)
Zhang, Xiaohan (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) Zheng, Mei (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) Sun, Ningning (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) Acharya, Srijan (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) Zhang, Xiaowei (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) Kim, Kyeong-Man (Pharmacology Laboratory, College of Pharmacy, Chonnam National University) |
1 | Shiina, T., Kawasaki, A., Nagao, T. and Kurose, H. (2000) Interaction with -arrestin determines the difference in internalization behavor between - and -adrenergic receptors. J. Biol. Chem. 275, 29082-29090. DOI |
2 | Vickery, R. G. and von Zastrow, M. (1999) Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. J. Cell Biol. 144, 31-43. DOI |
3 | Violin, J. D., DiPilato, L. M., Yildirim, N., Elston, T. C., Zhang, J. and Lefkowitz, R. J. (2008) -adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics. J. Biol. Chem. 283, 2949-2961. DOI |
4 | Wehbi, V. L., Stevenson, H. P., Feinstein, T. N., Calero, G., Romero, G. and Vilardaga, J. P. (2013) Noncanonical GPCR signaling arising from a PTH receptor-arrestin- complex. Proc. Natl. Acad. Sci. U.S.A. 110, 1530-1535. DOI |
5 | Williams, J. T., Ingram, S. L., Henderson, G., Chavkin, C., von Zastrow, M., Schulz, S., Koch, T., Evans, C. J. and Christie, M. J. (2013) Regulation of mu-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacol. Rev. 65, 223-254. DOI |
6 | Yang, M., He, R. L., Benovic, J. L. and Ye, R. D. (2009) -arrestin1 interacts with the G protein subunits and promotes -dependent Akt signaling for activation. Biochem. J. 417, 287-296. DOI |
7 | Zheng, M., Cheong, S. Y., Min, C., Jin, M., Cho, D. I. and Kim, K. M. (2011) -arrestin2 plays permissive roles in the inhibitory activities of RGS9-2 on G protein-coupled receptors by maintaining RGS9-2 in the open conformation. Mol. Cell. Biol. 31, 4887-4901. DOI |
8 | Ferguson, S. S., Downey, W. E., 3rd, Colapietro, A. M., Barak, L. S., Menard, L. and Caron, M. G. (1996) Role of -arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science, 271, 363-366. DOI |
9 | Cho, E. Y., Cho, D. I., Park, J. H., Kurose, H., Caron, M. G. and Kim, K. M. (2007) Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine receptor. Mol. Endocrinol. 21, 2242-2254. DOI |
10 | Feinstein, T. N., Yui, N., Webber, M. J., Wehbi, V. L., Stevenson, H. P., King, J. D., Jr., Hallows, K. R., Brown, D., Bouley, R. and Vilardaga, J. P. (2013) Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. J. Biol. Chem. 288, 27849-27860. DOI |
11 | Giros, B., Martres, M. P., Sokoloff, P. and Schwartz, J. C. (1990) Gene cloning of human dopaminergic receptor and identification of its chromosome. C. R. Acad. Sci. III, Sci. Vie 311, 501-508. |
12 | Hausdorff, W. P., Caron, M. G. and Lefkowitz, R. J. (1990) Turning off the signal: desensitization of -adrenergic receptor function. FASEB J. 4, 2881-2889. DOI |
13 | Hepler, J. R. and Gilman, A. G. (1992) G proteins. Trends Biochem. Sci. 17, 383-387. DOI |
14 | Kim, K. M., Valenzano, K. J., Robinson, S. R., Yao, W. D., Barak, L. S. and Caron, M. G. (2001) Differential regulation of the dopamine and receptors by G protein-coupled receptor kinases and -arrestins. J. Biol. Chem. 276, 37409-37414. DOI |
15 | Lohse, M. J., Benovic, J. L., Codina, J., Caron, M. G. and Lefkowitz, R. J. (1990) -Arrestin: a protein that regulates -adrenergic receptor function. Science 248, 1547-1550. DOI |
16 | Nobles, K. N., Xiao, K., Ahn, S., Shukla, A. K., Lam, C. M., Rajagopal, S., Strachan, R. T., Huang, T. Y., Bressler, E. A., Hara, M. R., Shenoy, S. K., Gygi, S. P. and Lefkowitz, R. J. (2011) Distinct phosphorylation sites on the -adrenergic receptor establish a barcode that encodes differential functions of -arrestin. Sci. Signal. 4, ra51. |
17 | Zheng, M., Zhang, X., Guo, S., Zhang, X., Min, C., Cheon, S. H., Oak, M. H., Kim, Y. R. and Kim, K. M. (2016) Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors. Biochim. Biophys. Acta 1863, 77-90. DOI |
18 | Lohse, M. J., Lefkowitz, R. J., Caron, M. G. and Benovic, J. L. (1989) Inhibition of -adrenergic receptor kinase prevents rapid homologous desensitization of -adrenergic receptors. Proc. Natl. Acad. Sci. U.S.A. 86, 3011-3015. DOI |
19 | Mahon, M. J., Bonacci, T. M., Divieti, P. and Smrcka, A. V. (2006) A docking site for G protein subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways. Mol. Endocrinol. 20, 136-146. DOI |
20 | Min, C., Zheng, M., Zhang, X., Caron, M. G. and Kim, K. M. (2013) Novel roles for -arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine receptors. Br. J. Pharmacol. 170, 1112-1129. DOI |
21 | Bizzozero, O. A. (1997) The mechanism and functional roles of protein palmitoylation in the nervous system. Neuropediatrics 28, 23-26. DOI |
22 | Pitcher, J. A., Inglese, J., Higgins, J. B., Arriza, J. L., Casey, P. J., Kim, C., Benovic, J. L., Kwatra, M. M., Caron, M. G. and Lefkowitz, R. J. (1992) Role of subunits of G proteins in targeting the -adrenergic receptor kinase to membrane-bound receptors. Science 257, 1264-1267. DOI |
23 | Robinson, S. W. and Caron, M. G. (1997) Selective inhibition of adenylyl cyclase type V by the dopamine receptor. Mol. Pharmacol. 52, 508-514. DOI |
24 | Shenoy, S. K. and Lefkowitz, R. J. (2005) Receptor-specific ubiquitination of -arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes. J. Biol. Chem. 280, 15315-15324. DOI |
25 | Benovic, J. L., Kuhn, H., Weyand, I., Codina, J., Caron, M. G. and Lefkowitz, R. J. (1987) Functional desensitization of the isolated -adrenergic receptor by the -adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) Proc. Natl. Acad. Sci. U.S.A. 84, 8879-8882. DOI |
26 | Benovic, J. L., Strasser, R. H., Caron, M. G. and Lefkowitz, R. J. (1986) -adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl. Acad. Sci. U.S.A. 83, 2797-2801. DOI |
27 | Bornancin, F. and Parker, P. J. (1997) Phosphorylation of protein kinase on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state. J. Biol. Chem. 272, 3544-3549. DOI |
28 | Cho, D., Zheng, M., Min, C., Ma, L., Kurose, H., Park, J. H. and Kim, K. M. (2010a) Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine receptors. Mol. Endocrinol. 24, 574-586. DOI |
29 | Cho, D. I., Beom, S., Van Tol, H. H., Caron, M. G. and Kim, K. M. (2006) Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine and receptors. Biochem. Biophys. Res. Commun. 350, 634-640. DOI |
30 | Cho, D. I., Zheng, M. and Kim, K. M. (2010b) Current perspectives on the selective regulation of dopamine and receptors. Arch. Pharm. Res. 33, 1521-1538. DOI |