• Journal of the Korean Chemical Society
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• v.57 no.1
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• pp.138-146
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• 2013

This study examined the characteristics of the National Assessment of Educational Achievement (NAEA) in Science according to gender. It investigated gender achievement differences in the science section of the 2010 NAEA, the ratio of gender difference in achievement, the ratio of correct answers within each content domain and behavioral domain, and the items which showed high differences between males and females. The results indicate first, that, for 9th graders, females outperformed males in academic achievement in science. Second, with respect to the ratio of correct answers, males outperformed females in the advanced and below basic level groups, but females outperformed males in intermediate level groups. Third, females outperformed males in knowledge and inquiry in the behavior domains, and in chemistry and biology in the content domains. Fourth, an analysis of the items showing the largest gender gap indicated that males outperformed females in interpreting data, while females outperformed males in the items concerned with daily life and items related to the memorization of rules. This research on gender differences in science will allow teachers to complement the weaknesses of students when they study science, and support improved instructional methods in science.

• Journal of The Korean Association For Science Education
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• v.32 no.10
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• pp.1524-1536
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• 2012

Science attitudes affect the quality of learning, and they are considered as one of the major concerns in science education. It is necessary to analyze the proximity between concepts with science attitudes. Accordingly, this study was designed to analyze the proximity of the concept related to photosynthesis as it changed after class according to the levels of science attitudes. A survey on the concept of photosynthesis and science attitudes before and after class was conducted on 270 7th-grade students. The concept of photosynthesis was composed of 'the place of photosynthesis,' 'products of photosynthesis,' 'reactants of photosynthesis,' and 'environmental factors.' The proximity of the concept of photosynthesis was analyzed through the utilization of multidimensional scaling (MDS). The research results were as follows: (1) Students changed the proximity between concepts by acquiring concrete concepts through class. (2) The upper group in science attitudes tends to be closer to the proximity between scientific concepts through class, compared to the intermediate and lower groups. (3) In all students with entire levels of science attitudes, non-scientific concepts continued to exist even after class, and the non-scientific concepts were deemed to interfere with the proximity between scientific concepts related to photosynthesis. (4) Students turned out to be aware of the concepts related to each other in four areas associated with photosynthesis. That is, it can be said that students are closely aware of the place where photosynthesis can occur and the materials needed as well as materials generated as a result of photosynthesis and the materials needed in terms of concepts related to photosynthesis.

• Journal of The Korean Association For Science Education
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• v.42 no.1
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• pp.161-176
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• 2022

This study developed an MEA program to which the invention technique was applied and analyzed the conceptual change of students. The MEA activity applying the invention technique (TRIZ) was composed of the topic of making a paper electric circuit in the section 'Using electricity' presented in the 6th grade textbook. As a way to materialize ideas for problem solving, among the TRIZ techniques, division, integration, multi-purpose, overlapping, subtraction, and converse techniques were extracted and applied. The devised program consists of examining invention techniques (1st session), problem-solving (2nd and 3rd sessions), and expressing the problem-solving process (4th session). As a result of applying to 6th grade elementary school students, it was confirmed that the scientific concept of the experimental group participating in the MEA class to which the invention technique was applied was improved compared to the control group participating in the general class. As a result of calculating the scientific concept improvement index, the control group showed a low educational effect of 0.15, and the experimental group showed an intermediate educational effect of 0.69. This study is meaningful in that it suggests a specific way to graft invention education into science subjects.

• Molecules and Cells
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• v.26 no.5
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• pp.459-461
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• 2008

Much research evidence supports the hypothesis that chronic, low-grade inflammation related to innate immunity may play an important role in the pathophysiology of type 2 diabetes mellitus (T2DM). Runt-related transcription factor 2 (RUNX2; MIM# 600211) acts as a scaffold that controls the integration, organization, and assembly of nucleic acids. To examine whether the novel promoter variant in RUNX2 is associated with the risk of T2DM and related phenotypes, RUNX2-742G > T was genotyped in 378 T2DM patients and 382 normal controls recruited in the Korean T2DM Study. Statistical analysis revealed that RUNX2-742G > T was associated with serum triglyceride level (TG) in nondiabetic controls, although it was not associated with the risk of T2DM. Individuals who carry T/T, T/G, and G/G genotypes had the highest ($2.061{\pm}0.20$), intermediate ($2.01{\pm}0.19$), and the lowest ($1.97{\pm}0.18$) levels of log [TG (mmol/l)] (P = 0.007), respectively. Our data on this important variant of RUNX2 suggest that lipid metabolism might be affected by genetic polymorphisms in the promoter region.

• Journal of Chest Surgery
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• v.43 no.6
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• pp.790-792
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• 2010

A 77-year-old man presented with a huge protruding mass on the left anterior chest wall. The tumor was resected and diagnosed as dermatofibrosarcoma protuberans (DFSP). DFSP is an uncommon, intermediate-grade mesenchymal cutaneous tumor which extends deep into subcutaneous tissue and may invade through the fascial planes and into muscle but rarely metastasize. Histologically, DFSP is composed of spindle cells arranged in an irregularly whorled or storiform pattern. The histological diagnosis can be confirmed with immunohistochemical staining for CD34. We report a case of DFSP. The tumor was completely excised and the chest wall was reconstructed using latissimus dorsi muscle flap and skin graft.

• Economic and Environmental Geology
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• v.19 no.2
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• pp.147-151
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• 1986

K-Ar ages on biotites have been determined from the Proterozoic Buncheon and Hongjesa granitic rocks in comparison with the Rb-Sr whole-rock ages to investigate the ages of metamorphic events. The Rb-Sr whole-rock ages determinations on the Buncheon and Hongjesa granitoid rocks were previously reported as 2,100Ma and 1,700Ma, respectively. K-Ar ages on biotites separated from the studied rock have revealed three different age groups such as 1) 1,200~1,300Ma, 2) 600~700Ma and 3) 300~400Ma. The Rb-Sr whole-rock ages for the granitic rocks represent the time of emplacement, whereas the K-Ar ages on biotites generally indicate the time of metamorphism or alteration. The large discordance in the two age systems may not be explained as indicating the cooling period of the granitic batholiths. The K-Ar ages on biotites from the granitoid rocks might not be simply interpreted as the age of the last phase of metamorphism, since the granitic rocks had been undergone multistages of amphibolite facies-metamorphism in the Precambrian period. During the multistages of intermediate grade metamorphism, $^{40}Ar$-loss could be inevitably taken place as the metamorphic temperatures went up above the blocking temperature of biotite ($300{\pm}50^{\circ}C$). The results of the K-Ar dating on biotites from this study are probably minimum ages or hydrothermal alteration ages.

• Clinical and Experimental Pediatrics
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• v.61 no.2
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• pp.53-58
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• 2018

Purpose: Although the prognosis is generally good in patients with intermediate-risk neuroblastoma, no consensus has been reached on the ideal treatment regimen. This study analyzed treatment outcomes and toxicities in patients younger than 18 months with stage 4 MYCN nonamplified neuroblastoma. Methods: We retrospectively analyzed 20 patients younger than 18 months newly diagnosed with stage 4 MYCN nonamplified neuroblastoma between January 2009 and December 2015. Patients received 9 cycles of chemotherapy and surgery, with or without local radiotherapy, followed by 12 cycles of differentiation therapy with 13-cis-retinoic acid. Chemotherapy consisted of alternating cycles of cisplatin, etoposide, doxorubicin, and cyclophosphamide (CEDC) and ifosfamide, carboplatin, and etoposide (ICE) regimens. Results: The most common primary tumor site was the abdomen (85%), and the most common metastatic sites were the lymph nodes (65%), followed by the bones (60%), liver (55%), skin (45%), and bone marrow (25%). At the end of induction therapy, 14 patients (70%) achieved complete response, with 1 achieving very good partial response, 4 achieving partial response, and 1 showing mixed response. Nine patients (45%) received local radiotherapy. At a median follow-up of 47 months (range, 17-91 months), none of these patients experienced relapse, progression, or secondary malignancy, or died. Three years after chemotherapy completion, none of the patients had experienced grade ${\geq}3$ late adverse effects. Conclusion: Patients younger than 18 months with stage 4 MYCN nonamplified neuroblastoma showed excellent outcomes, without significant late adverse effects, when treated with alternating cycles of CEDC and ICE, followed by surgery and differentiation therapy.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.697-702
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• 2016

Background: The Asia-Pacific Breast Initiatives (APBI) I and II registries were established to collect safety data for patients with early stage breast cancer receiving adjuvant docetaxel-based regimens in the Asia-Pacific region. Materials and Methods: Data from the two registries were combined to perform a safety analysis. Participants in the registry were women with early stage operable breast cancer with an intermediate or high risk of recurrence. These women received adjuvant chemotherapy that included docetaxel between 2006 and 2011. Adverse events (AEs) were recorded and analyzed. Results: Data were collected from 3,224 patients from 13 countries. The mean dose intensity of docetaxel was 24.1, 22.7, $25.1mg/m^2/week$ among patients receiving docetaxel-based monotherapy, combination therapy and sequential therapy, respectively. Granulocyte colony-stimulating factor (G-CSF) was given with docetaxel to 41.8% of women and 20.6% of women receiving prophylactic antibiotics. Adverse events were reported in 86% of patients (anthracycline-containing regimens vs. non-anthracycline regimens; 87% vs. 80%). The most common adverse events were alopecia, nausea, neutropenia, vomiting, and myalgia. Adverse events NCI CTCAE ${\geq}$Grade 3 were reported in 45.4% of patients. Serious adverse events were reported in 13% of patients, of which 2.5% led to study discontinuation. Forty-six deaths (1.4%) were reported, with no significant difference between regimens. Conclusions: The safety parameters of adjuvant docetaxel therapy used to treat sequential Asian women were comparable to those reported in clinical trials evaluating the role of adjuvant docetaxel. No unusual adverse events linked to Asia-Pacific region patients were observed.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.6
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• pp.128-140
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• 2003

The purpose of this research was to present characteristics for the classification of biotopes and classification method of biotopes as basic data for ecological landscape planning in Metropolitan Daegu. The results of this study were as follows. 1) The study identified fifteen characteristics for classification of biotopes. Ecological landscape characteristics were divided into structural and functional factors. There are six structural factors such an inclination, and nine functional factors such as temperature. 2) The study area was separated into sixty eight biotope types. For example, an industrial district was divided into two biotope types: a biotope type of an industrial district with abundant green space, and a biotope type of an industrial district with scarce green space. 3) In the result of cluster analysis using the average linkage method between groups, biotope groups were divided into fifteen clusters and biotope groups were divided into seven clusters. Each cluster was named according to the features of a descriptive statistics analysis. For example, cluster 8 was identified as a biotope type with an impermeable pavement rate of more than 90 percent and an afforestation rate under 10 percent. 4) Fifteen biotope groups were converted to land use patterns for remote application and utilization of urban biotope in city planning. Biotope groups of a building area beyond an intermediate floor with an afforestation rate under 20-30 percent was converted to a land use pattern such as a tall apartment complex or commercial district. When examining the characteristics that were established in this research, there was a limit to achieve the objective of grade-classification because of a lack of related basic data. The research of landscape ecological characteristics for the classification of biotopes could not be completed due to a lack of time and resources, thus the study of ecological landscape characteristics will be accomplished over time.

• The Journal of the Korea Contents Association
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• v.14 no.3
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• pp.301-313
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• 2014

This study aimed to identify the correlation of stress-coping, humor sense, and adaptation to college of nursing students. Three hundred thirty eight subjects completed a structured questionnaire in June 2012. Data were analyzed using SPSS/WIN 21.0 program. The mean scores were as follows; stress-coping 43.33, humor sense 72.18, and adaptation to college 68.02. It meant beyond the intermediate level. Significant differences were found between adaptation to college scores and general characteristics such as gender, academic year, family type, economic status, campus life satisfaction, relation with faculties, grade, and the relationship with the opposite gender. There was significant but weak correlation of stress-coping, humor sense, and adaptation to college. These results suggest that it is necessary to develop individualized education programs considering students' characteristics. Additionally, university adjustment related factors should be studied.