• 제목/요약/키워드: Interfacial Flow

검색결과 219건 처리시간 0.03초

Spherical and cylindrical microencapsulation of living cells using microfluidic devices

  • Hong, Joung-Sook;Shin, Su-Jung;Lee, Sang-Hoon;Wong, Edeline;Cooper-White, Justin
    • Korea-Australia Rheology Journal
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    • 제19권3호
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    • pp.157-164
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    • 2007
  • Microencapsulation of cells within microfluidic devices enables explicit control of the membrane thickness or cell density, resulting in improved viability of the transplanted cells within an aggressive immune system. In this study, living cells (3T3 and L929 fibroblast cells) are encapsulated within a semi-permeable membrane (calcium crosslinked alginate gel) in two different device designs, a flow focusing and a core-annular flow focusing geometry. These two device designs produce a bead and a long microfibre, respectively. For the alginate bead, an alginate aqueous solution incorporating cells flows through a flow focusing channel and an alginate droplet is formed from the balance of interfacial forces and viscous drag forces resulting from the continuous (oil) phase flowing past the alginate solution. It immediately reacts with an adjacent $CaCl_2$ drop that is extruded into the main flow channel by another flow focusing channel downstream of the site of alginate drop creation. Depending on the flow conditions, monodisperse microbeads of sizes ranging from $50-200\;{\mu}m$ can be produced. In the case of the microfibre, the alginate solution with cells is extruded into a continuous phase of $CaCl_2$ solution. The diameter of alginate fibres produced via this technique can be tightly controlled by changing both flow rates. Cell viability in both forms of alginate encapsulant was confirmed by a LIVE/DEAD cell assay for periods of up to 24 hours post encapsulation.

균질의 회전유체에 고밀도유체 주입실험 (Injection of a Denser Fluid into a Rotating Cylindrical Container Filled with Homogeneous Lighter Fluid)

  • 나정열;황병준
    • 한국해양학회지
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    • 제30권4호
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    • pp.355-364
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    • 1995
  • f-plane 혹은 $\beta$-plane을 갖고 강체 회전중인 균질수에 외부로부터 고밀도의 유체 를 계속 주입시 주입된 고밀도 류의 확장형태와 이와 대응하는 기존의 균질수(상층수) 의 흐름을 관찰하였다. 고밀도류는 주입후 편향력에 의해 서안을 따라 흐르면서 내부 로 침투 확장하여 회전축에 비대칭인 모양을 보인다. 특히 $\beta$-plan에서는 바닥 경사도 의 증가에 따른 압력 경도력의 증가에 의한 서안을 따라 흐르는 속도가 증가되고 결국 편향력의 증가로 서안에서의 폭이 f-plane보다 좁게 나타난다. 그러나 남쪽에 이르러 서는 유입수의 국지적인 두께증가로 인해 확장 속도가 동시에 경계면상에서 의 혼합을 유발시키기도 한다. 유입된 고밀도류의 상층의 와도발생과 관련한 역할은 확장경로상 의 국지적인 지형효과의 유발과 유입으로 인한 상층수의 수직운동, 즉 vortex-tube stretching 효과를 발생시키는 것으로 볼 수 있으나 f-plane의 경우는 후자에 해당하 는 반시계 방향의 축대칭류를 생성시킴으로써 지형효과는 서안 경계층에만 존재하는 것으로 관찰되었으며 이때의 지형효과는 북향의 매우 약한 서안 경계류로 나타나고 있 다. 한편 $\beta$-plan에서 의 유입수의 역할은 실험면적의 동쪽반인 내부흐름에서는 h보다 는 dh/SUB $\beta$/dt의 크기가 우세하여 결국 상대와도의 감소경향인 시계방향의 음의 와 도(negative vorticity)의 발생과 서쪽반에서는 경계면의 경사 (tilting)에 의한 지형 효과가 극대화되어 유입수의 방향과 정반대인 강한 흐름이 나타나고 있다.

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종이 도공용 라텍스의 계면(界面) 및 유동특성(流動特性)에 관한 연구(硏究) (Interfacial and Flow Properties of Latices for Paper Coating)

  • 이용규
    • Journal of the Korean Wood Science and Technology
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    • 제22권1호
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    • pp.85-90
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    • 1994
  • The flow properties of binder latices for paper coating were investigated, together with dynamic viscoelastic properties of latex films and electron micrographs of latices, under various conditions. The amphoteric latex, binder pigment latex and anionic latex were used in this work. The amphoteric latex has both anionic and cationic functional group on its surface. The binder-pigment with a core-shell structure has dual functions : plastic pigment and binder. The low shear viscosity of binder latices and clay slurry were measured with Brookfield vis cometer. At low-shear rates. the viscosity decreased with increasing particle size of latex. On the amphoteric latex surface, the carboxyl groups are assumed to be fully dissociated over the region of pH 9~12, but the density of negative groups seems to be increased because of the gradual decrease in the degree of dissociation of amino groups. Since the apparent particle size of latex increases with surface charge, the electroviscous effect can be observed. On the anionic latex surface, the charge density is assumed to be nearly constant above pH 8. However, below pH 8 the coagulation of particles could be observed probably because of the decrease in the charge density.

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DEVELOPMENT OF THE MULTI-DIMENSIONAL HYDRAULIC COMPONENT FOR THE BEST ESTIMATE SYSTEM ANALYSIS CODE MARS

  • Bae, Sung-Won;Chung, Bub-Dong
    • Nuclear Engineering and Technology
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    • 제41권10호
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    • pp.1347-1360
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    • 2009
  • A multi-dimensional component for the thermal-hydraulic system analysis code, MARS, was developed for a more realistic three-dimensional analysis of nuclear systems. A three-dimensional and two-fluid model for a two-phase flow in Cartesian and cylindrical coordinates was employed. The governing equations and physical constitutive relationships were extended from those of a one-dimensional version. The numerical solution method adopted a semi-implicit and finite-difference method based on a staggered-grid mesh and a donor-cell scheme. The relevant length scale was very coarse compared to commercial computational fluid dynamics tools. Thus a simple Prandtl's mixing length turbulence model was applied to interpret the turbulent induced momentum and energy diffusivity. Non drag interfacial forces were not considered as in the general nuclear system codes. Several conceptual cases with analytic solutions were chosen and analyzed to assess the fundamental terms. RPI air-water and UPTF 7 tests were simulated and compared to the experimental data. The simulation results for the RPI air-water two-phase flow experiment showed good agreement with the measured void fraction. The simulation results for the UPTF downcomer test 7 were compared to the experiment data and the results from other multi-dimensional system codes for the ECC delivery flow.

NUMERICAL INVESTIGATION OF THE SPREADING AND HEAT TRANSFER CHARACTERISTICS OF EX-VESSEL CORE MELT

  • Ye, In-Soo;Kim, Jeongeun Alice;Ryu, Changkook;Ha, Kwang Soon;Kim, Hwan Yeol;Song, Jinho
    • Nuclear Engineering and Technology
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    • 제45권1호
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    • pp.21-28
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    • 2013
  • The flow and heat transfer characteristics of the ex-vessel core melt (corium) were investigated using a commercial CFD code along with the experimental data on the spreading of corium available in the literature (VULCANO VE-U7 test). In the numerical simulation of the unsteady two-phase flow, the volume-of-fluid model was applied for the spreading and interfacial surface formation of corium with the surrounding air. The effects of the key parameters were evaluated for the corium spreading, including the radiation, decay heat, temperature-dependent viscosity and initial temperature of corium. The results showed a reasonable trend of corium progression influenced by the changes in the radiation, decay heat, temperature-dependent viscosity and initial temperature of corium. The modeling of the viscosity appropriate for corium and the radiative heat transfer was critical, since the front progression and temperature profiles were strongly dependent on the models. Further development is required for the code to consider the formation of crust on the surfaces of corium and the interaction with the substrate.

유한요소 해석을 이용한 나노임프린트 가압 공정에서 발생하는 결함 원인에 대한 연구 (A Study on Cause of Defects in NIL Molding Process using FEM)

  • 송남호;손지원;김동언;오수익
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2007년도 추계학술대회 논문집
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    • pp.364-367
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    • 2007
  • In nano-imprint lithography (NIL) process, which has shown to be a good method to fabricate polymeric patterns, several kinds of pattern defects due to thermal effects during polymer flow and mold release operation have been reported. A typical defect in NIL process with high aspect ratio and low resist thickness pattern is a resist fracture during the mold release operation. It seems due to interfacial adhesion between polymer and mold. However, in the present investigation, FEM simulation of NIL molding process was carried out to predict the defects of the polymer pattern and to optimize the process by FEA. The embossing operation in NIL process was investigated in detail by FEM. From the analytical results, it was found that the lateral flow of polymer resin and the applied pressure in the embossing operation induce the weld line and the drastic lateral strain at the edge of pattern. It was also shown that the low polymer-thickness result in the delamination of polymer from the substrate. It seems that the above phenomena cause the defects of the final polymer pattern. To reduce the defect, it is important to check the initial resin thickness.

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연료탱크 슬로싱 소음 저감을 위한 배플 및 다공성 물질 설치에 따른 유동해석 연구 (A NUMERICAL STUDY ON FLOWS IN A FUEL TANK WITH BAFFLES AND POROUS MEDIA TO REDUCE SLOSHING NOISE)

  • 이상혁;허남건
    • 한국전산유체공학회지
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    • 제14권2호
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    • pp.68-76
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    • 2009
  • The sloshing tank causes the instability of the fluid flows and the fluctuation of the impact pressure by the liquid on the tank. These flow characteristics inside the sloshing tank can generate the uncomfortable sloshing noise. In the present study, a numerical analysis for the reduction of a fuel tank sloshing noise was performed. To simulate the flow characteristics in a sloshing tank with partially filled liquid, a VOF method was used for interfacial flows by applying a momentum source term for the sloshing motion in a non-inertial reference frame. This numerical method was verified by comparing its results with the available experimental data. For the reduction of the sloshing noise, the horizontal and vertical baffles and porous media inside a sloshing tank were considered and numerically analyzed in the present study. For various installations of these baffles and porous media, the characteristics of the liquid behavior in the sloshing tank were obtained along with the impact pressure on the wall and the height of the free surface along the wall. These basic results can be used for the design of the actual vehicular fuel tank with the reduced sloshing noise.

Layering시 복합레진 층간의 계면 결합에서 oxygen inhibition layer가 필수적인가? (IS AN OXYGEN INHIBITION LAYER ESSENTIAL FOR THE INTERFACIAL BONDING BETWEEN RESIN COMPOSITE LAYERS?)

  • 김선영;조병훈;백승호;이인복
    • Restorative Dentistry and Endodontics
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    • 제33권4호
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    • pp.405-412
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    • 2008
  • 본 연구의 목적은 여러 가지 계면조건의 변화를 통해서 layering시 복합레진 층간의 결합에 oxygen inhibition layer (OIL)가 필수적인지를 고찰해보는 것이다. 가로 $\times$ 세로 $\times$ 두께가 16 $\times$ 28 $\times$ 2.5 mm인 알루미늄판에 지름 3.7 mm의 구멍을 형성하여 몰드를 제작하고 다음과 같이 복합레진 (Z-250, 3M ESPE)을 충전하여 광중합하였다. 1 군: 하층판에 복합레진을 충전하고 광중합 한 후, 상층판을 접합하고 레진을 충전하여 광중합을 하였다 (OIL를 남김). 2 군: 하층판에 복합레진을 충전하고 광중합 한 후 acetone에 적신 cotton으로 문질러서 OIL를 제거하고 상층판을 접합하여 복합레진을 충전하고 광중합을 하였다 (OIL를 제거). 3 군: 하층판에 복합레진을 충전하고 Mylar strip을 접합하여 공기와의 접촉을 차단한 후 광중합을 하였다. Mylar strip을 제거하고 상층판을 접합 후 복합레진을 충전하여 광중합을 하였다 (OIL형성을 억제). 4 군: 하층판에 복합레진을 충전하고 광중합 한 후 glycerin을 OIL 표면에 도포하고 다시 광중합하였다. 상층판을 접합하여 복합레진을 충전하고 광중합을 하였다 (OIL를 중합). 5군 (대조군): 하층판과 상층판의 경계에 복합레진층의 계면이 위치하지 않도록 복합레진을 bulk충전하였다 (계면형성 없이 bulk 충전한 복합레진). 24 시간 100% 습도에서 보관 후 상층판과 하층판 사이의 계면 전단결합강도를 측정하고 파절 양상을 관찰하였다. 계면을 통한 중합과정의 확산을 관찰하기 위하여 제조한 광개시제가 들어있지 않은 실험적 복합레진 (Exp_Com)을 몰드에 충전하고 상부에 flowable 복합 레진 (Aelite Flow) 또는 접착레진 (ScotchBond Multipurpose)을 접촉시킨 후 광조사하였다. 몰드내의 미중합된 Exp_Com을 acetone bath 에서 5 분 동안 제거한 후 몰드내에 다시 Aelite Flow를 충전하고 광중합을 시행하였다. 경화된 복합레진 시편의 단면을 관찰하여 Exp_Com 층의 두께를 측정하였다. OIL를 배제하거나 중합시킨 2-4군은 OIL이 존재하는 1 군과 통계적으로 유의한 결합강도의 차이를 보이지 않았으며, Mylar strip을 이용하여 OIL의 생성을 억제했던 3군과 glycerin을 도포하여 OIL를 중합시킨 4군은 계면을 생성하지 않은 대조군인 5 군과도 통계적으로 유의한 차이를 보이지 않았다. 중합과정의 확산에 의해 중합개시제가 포함되지 않은 Exp_Com내에 중합된 층이 생겨난 것을 시각적으로 확인할 수 있었으며, Exp_Com의 중합층 두께는 flowable 레진의 경우 20.95 (0.90) um였고 접착레진의 경우 42.13 (2.09) 였다.

Jute fiber Green Composite의 커플링제에 의한 물리적 인자의 변화와 기계적 특성 향상 (Relations between Physical Parameters and Improvement of Mechanical Properties in Jute Fiber Green Composites by Maleic Anhydride Coupler)

  • 이정훈;변준형;김병선;박종만;황병선
    • Composites Research
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    • 제20권1호
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    • pp.23-31
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    • 2007
  • Jute fiber Green Composite의 기계적 향상을 위한 계면특성을 향상시키기 위하여 커플링제를 도입하여 첨가량에 따른 특성변화를 실험적으로 규명하였다. Maleic anhydride grafted popolypropylene(MAPP)는 자연섬유와의 계면특성의 향상에서 물리화학적 역할을 하는 것으로 판단된다. MAPP에 의한 용융상태에서의 낮아진 수지의 점도는 흐름성이 향상되어 섬유의 계면과의 접촉 면적을 확대시킨다. 약 80mm의 jute 장섬유 mat에 maleated coupler가 혼합된 PP 복합재의 물성 향상과 열가소성수지의 물리적 변화와의 관계를 고찰하였다. 이 물리적 현상을 유동지수(MI: Melting flow index) 및 점도, contact angle, 복합재료 두께, 계면전단강도, morphology 분석 등의 인자들을 이용하여 기계적 물성 향상에 기여하는 정도를 확인하였다. 특히 유동지수(MI)와 점도, MAPP의 혼합량은, 전당강도(IFSS), 인장 및 굴곡 강도와 인장탄성률의 향상과 매우 관계가 있음을 실험 결과를 통하여 확인하였다.

보스-리브 시험 시 펀치 형상 및 마찰 조건에 따른 변형 양상에 대한 연구 (Effect of Punch Design and Friction Condition on Deformation Pattern in Boss and Rib Test)

  • 윤여웅;강성훈
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2009년도 추계학술대회 논문집
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    • pp.332-337
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    • 2009
  • Recently, boss and rib test based on backward extrusion process was proposed to quantitative evaluate the interfacial friction condition in bulk forming process. In this test, the tube-shaped punch with hole pressurizes the workpiece so that the boss and rib are formed along the hole and outer surface of the punch. It was experimentally and numerically revealed that the height of boss is higher than that of the rib under the severe friction condition. This work is focused on the effect of the punch design and friction condition on deformation pattern in boss and rib test. From the boss and rib test simulations, it was found that there is slight variation in both the heights of boss and rib according to the length of punch land, nose radius, and face angle. However the hole diameter of the punch and the clearance between the punch and die have a significant influence on the heights of the boss and rib. In addition, the effect of flow stress was also investigated on the deformation patterns through FE simulations.

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