• 대한화학회지
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• 제33권5호
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• pp.459-467
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• 1989

계면활성제가 수용액 중에 용해되면 용액내에서 micelle이라는 응집체를 형성하며, micelle은 그 내부에 oil를 용해시켜 swollen micelle을 형성하게 된다. 실제로 물-oil-계면활성계의 상평형도상에서 micelle과 swollen micelle은 동일영역에 존재하게 되나 일반적으로 micelle과 swollen micelle의 형성에 관해서는 서로 다른 관점으로 취급되어 왔다. 본 연구에서는 이러한 계면활성제 응집체의 형성에 관한 일관된 열역학적 모델을 제시하고자 한다. 모든 경우에 저농도 영역에서 이상용액 이론을 적용하였으며, micelle 형성에너지는 소수성 작용에너지와 계면에서의 표면에너지의 합으로 표시하였다. 이론식으로부터 임계마이셀농도, 평균응집분자수, 용해비 등을 예측하였으며 실험관측치와 비교하였다.

• Steel and Composite Structures
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• 제19권5호
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• pp.1299-1319
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• 2015

This paper presents a detailed parametric study, conducted using finite element tools to cover a range of several geometric and material parameters, on the behaviour of thin-walled partially encased composite (PEC) columns. The PEC columns studied herein are composed of thin-walled built-up H-shaped steel sections with concrete infill cast between the flanges. Transverse links are provided between the opposing flanges to improve resistance to local buckling. The parametric study is confined to eccentrically-loaded columns subjected to major axis bending only. The parameters that were varied include the overall column slenderness ratio (L/d), load eccentricity ratio (e/d), link spacing-to-depth ratio (s/d), flange plate slenderness ratio (b/t) and concrete compressive strength ($f_{cu}$). The overall column slenderness ratio was chosen to be the primary variable with values of 5, 10 and 15. Other parameters were varied within each case of L/d ratio. The effects of the selected parameters on the behaviour of PEC columns were studied with respect to the failure mode, peak axial load, axial load versus average axial strain response, axial load versus lateral displacement response, moment versus lateral displacement behaviour and the axial load-moment interaction diagram. The results of the parametric study are presented in the paper and the influences of each of the parameters investigated are discussed.

• 디지털산업정보학회논문지
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• 제7권3호
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• pp.37-42
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• 2011

Nowadays software developers are moving from conventional software process technologies to the object-oriented paradigm. To develope the object-oriented softwares efficiently, various software metrics have been suggested. Coupling refers to the degree of independence between components of the system. It has long been well known that good software practice calls for minimizing coupling interaction. Many researches have been studied coupling metrics of the object- oriented systems. We review Chidamber and Kemerer's work & Li's work. In this paper, we study the coupling of the overall structures of object-oriented systems by analyzing the class diagram of UML. We propose four coupling metrics for object-oriented softwares. First, we use an established coupling metric for object- oriented systems as a basic coupling metric. Then we modify the basic coupling metric by including indirect coupling between classes, We also suggest two relative coupling metrics to measure coupling between subsystems. We investigate the theoretical soundness of the proposed metrics by the axioms of Briand et al. Finally, we apply the presented metrics to a practical case study. This coupling metric will be helpful to the software developers for their designing tasks by evaluating the coupling metric of the structures of object-oriented system and redesigning tasks of the system.

• 한국시스템다이내믹스연구
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• 제15권3호
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• pp.81-104
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• 2014

This study aimed to suggest the directions for the landscape protection of Sindu-ri coastal dune based on its ecological system. The study investigated ecological systems of the coastal dune followed by damage causes of coastal dune according to the land use change, and landscape value of coastal dune in the study area. In order to construct causal-effect feedback loop, systems thinking was performed. Result of this study showed that the area of coastal dune and the amount of sand are maintained by the interaction with sand beach while they are affected by wind direction, wind speed, and dune plants. It was also found that the changes of land use pattern, increasing commercial area, and planted windbreak forest damaged to the coastal dune. In addition, size of coastal dune and growing number of dune plants increased landscape value of coastal dune and tourist draw. However increasing tourists have constantly affected land use changes and have damaged to coastal dune area. In sum, planning for land use regulation, rest-year system areas, promotion and education for coastal dune, dune plants protection, and windbreak management should be taken into account for landscape protection in coastal dune.

• Structural Engineering and Mechanics
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• 제62권4호
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• pp.381-389
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• 2017

In the present study, the advanced procedure has been proposed to estimate higher accuracy of embedment of pipes that are installed on soft clay seabed. Numerical simulation by OrcaFlex simulation code was performed to investigate dynamic seabed embedment, and two steps, i.e., static and dynamic analysis, were adopted. In total, four empirical curves were developed to estimate the seabed embedment including dynamic phenomena, i.e., behaviour of vessel, environmental condition, and behaviour of nonlinear soil. The obtained results were compared with existing methods (named general method) such as design code or guideline to examine the difference of seabed embedment for existing and advance methods. Once this process was carried out for each case, a diagram for estimating seabed embedment was established. The applicability of the proposed method was verified through applied examples with field survey data. This method will be very useful in predicting seabed embedment on soft clay, and the structural behaviours of installed subsea pipelines can be changed by the obtained seabed embedment in association with on-bottom stability, free span, and many others.

• Computers and Concrete
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• 제15권4호
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• pp.643-671
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• 2015

Chloride induced reinforcement corrosion is widely accepted to be the most frequent mechanism causing premature degradation of reinforced concrete members, whose economic and social consequences are growing up continuously. Prevention of these phenomena has a great importance in structural design, and modern Codes and Standards impose prescriptions concerning design details and concrete mix proportion for structures exposed to different external aggressive conditions, grouped in environmental classes. This paper focuses on reinforced concrete column section load carrying capacity degradation over time due to chloride induced steel pitting corrosion. The structural element is considered to be exposed to marine environment and the effects of corrosion are described by the time degradation of the axial-bending interaction diagram. Because chlorides ingress and consequent pitting corrosion propagation are both time-dependent mechanisms, the study adopts a time-variant predictive approach to evaluate residual strength of corroded reinforced concrete columns at different lifetimes. Corrosion initiation and propagation process is modelled by taking into account all the parameters, such as external environmental conditions, concrete mix proportion, concrete cover and so on, which influence the time evolution of the corrosion phenomenon and its effects on the residual strength of reinforced concrete columns sections.

• Nuclear Engineering and Technology
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• 제32권5호
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• pp.465-476
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• 2000

In a nuclear power plant, steam generator tubes cover a major portion of the primary pressure-retaining boundary. Thus very conservative approaches have been taken in the light of steam generator tube integrity According to the present criteria, tubes wall-thinned in excess of 40% should be plugged whatever causes are. However, many analytical and experimental results have shown that no safety problems exist even with thickness reductions greater than 40%. The present criterion was developed about twenty years ago when wear and pitting were dominant causes for steam generator tube degradation. And it is based on tubes with single cracks regardless of the fact that the appearance of multiple cracks is more common in general. The objective of this study is to review the conservatism of the present plugging criteria of steam generator tubes and to propose a new coalescence model for two adjacent through-wall cracks existing in steam generator tubes. Using the existing failure models and experimental results, we reviewed the conservatism of the present plugging criteria. In order to verify the usefulness of the proposed new coalescence model, we performed finite element analysis and some parametric studies. Then, we developed a coalescence evaluation diagram.

• Structural Engineering and Mechanics
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• 제69권5호
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• pp.499-509
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• 2019

While the wheel flat is an asymmetrical phenomenon in the railway, majority of researches have used two-dimensional models in the investigation of the effect of wheel flat on the wheel rail forces. This is due to the considerably low computational costs of two dimensional (2D) models although their reliability is questionable. This leaves us with the question of "what is the optimum modeling technique?". It is addressed in this research. For this purpose, two and three dimensional numerical models of railway vehicle/track interaction were developed. The three dimensional (3D) model was validated by comparisons of its results with those obtained from a comprehensive field tests carried out in this research and then, the results obtained from the 2D and 3D models were compared. The results obtained indicate that there are considerable differences between wheel/rail forces obtained from the 2D and 3D models in the conditions of medium to large wheel-flats. On the other hand, it was shown that the results of the 2D models are reliable for particular ranges of vehicle speed, railway track stiffness and wheel-fats lengths and depths. The results were used to draw a diagram, which presents the optimum modeling technique, compromising between the costs and accuracy of the obtained results.

• Steel and Composite Structures
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• 제38권6호
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• pp.739-749
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• 2021

This paper introduces an improved design equation to evaluate the resisting capacity of circular reinforced concrete (RC) columns partially strengthened with outer steel tube. When RC column members are required to be strengthened according to the change in the loadings considered and/or the deterioration progress in columns, wrapping up RC column with steel circular tube, which takes the form of concrete filled steel tube (CFST), has been popularly considered because of its structural advantage induced from the confinement effect. However, the relatively high construction cost of steel tube is restricting its use to the required region, while deriving the shape of a partial CFST column. To evaluate the resisting capacity of a partial CFST column, numerical analyses need to be performed, and a numerical model proposed in the previous study for the numerical analysis of full CFST columns is used to conduct parametric studies for the introduction of a design equation. The bond-slip effect developed along the interface between the in-filled concrete and the exterior steel tube is taken into consideration and the validity of the numerical model has been established through correlation studies between experimental data and numerical results for partial CFST circular columns. Moreover, parametric studies make it possible to introduce a design equation for determining the optimum length of outer steel tube which produces partial CFST circular columns.

• Journal of Microbiology and Biotechnology
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• 제32권6호
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• pp.718-729
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• 2022

Esophageal squamous cell carcinoma (ESCC) is the most common primary esophageal malignancy with poor prognosis. Here, due to the necessity for exploring potential therapies against ESCC, we obtained the gene expression data on ESCC from the TCGA and GEO databases. Venn diagram analysis was applied to identify common targets. The protein-protein interaction network was constructed by Cytoscape software, and the hub targets were extracted from the network via cytoHubba. The potential hub nodes as drug targets were found by pharmacophore-based virtual screening and molecular modeling, and the antitumor activity was evaluated through in vitro studies. A total of 364 differentially expressed genes (DEGs) in ESCC were identified. Pathway enrichment analyses suggested that most DEGs were mainly involved in the cell cycle. Three hub targets were retrieved, including CENPF, CCNA2 (cyclin A), and CCNB1 (cyclin B1), which were highly expressed in esophageal cancer and associated with prognosis. Moreover, amentoflavone, a promising drug candidate found by pharmacophore-based virtual screening, showed antiproliferative and proapoptotic effects and induced G1 in esophageal squamous carcinoma cells. Taken together, our findings suggested that amentoflavone could be a potential cell cycle inhibitor targeting cyclin B1, and is therefore expected to serve as a great therapeutic agent for treating esophageal squamous cell carcinoma.