• Title/Summary/Keyword: Interaction Model

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Transcriptome profiling identifies immune response genes against porcine reproductive and respiratory syndrome virus and Haemophilus parasuis co-infection in the lungs of piglets

  • Zhang, Jing;Wang, Jing;Zhang, Xiong;Zhao, Chunping;Zhou, Sixuan;Du, Chunlin;Tan, Ya;Zhang, Yu;Shi, Kaizhi
    • Journal of Veterinary Science
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    • v.23 no.1
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    • pp.2.1-2.18
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    • 2022
  • Background: Co-infections of the porcine reproductive and respiratory syndrome virus (PRRSV) and the Haemophilus parasuis (HPS) are severe in Chinese pigs, but the immune response genes against co-infected with 2 pathogens in the lungs have not been reported. Objectives: To understand the effect of PRRSV and/or HPS infection on the genes expression associated with lung immune function. Methods: The expression of the immune-related genes was analyzed using RNA-sequencing and bioinformatics. Differentially expressed genes (DEGs) were detected and identified by quantitative real-time polymerase chain reaction (qRT-PCR), immunohistochemistry (IHC) and western blotting assays. Results: All experimental pigs showed clinical symptoms and lung lesions. RNA-seq analysis showed that 922 DEGs in co-challenged pigs were more than in the HPS group (709 DEGs) and the PRRSV group (676 DEGs). Eleven DEGs validated by qRT-PCR were consistent with the RNA sequencing results. Eleven common Kyoto Encyclopedia of Genes and Genomes pathways related to infection and immune were found in single-infected and co-challenged pigs, including autophagy, cytokine-cytokine receptor interaction, and antigen processing and presentation, involving different DEGs. A model of immune response to infection with PRRSV and HPS was predicted among the DEGs in the co-challenged pigs. Dual oxidase 1 (DUOX1) and interleukin-21 (IL21) were detected by IHC and western blot and showed significant differences between the co-challenged pigs and the controls. Conclusions: These findings elucidated the transcriptome changes in the lungs after PRRSV and/or HPS infections, providing ideas for further study to inhibit ROS production and promote pulmonary fibrosis caused by co-challenging with PRRSV and HPS.

Effects of Nonverbal Communication of Flight Attendants on Customer Engagement and Brand Intimacy (항공사 승무원의 비언어 커뮤니케이션이 고객 인게이지먼트 및 브랜드 친밀감에 미치는 영향)

  • Yuna Choi;Namho Chung
    • Knowledge Management Research
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    • v.24 no.2
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    • pp.185-209
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    • 2023
  • The air travel industry, which had shrunk with COVID-19, is gaining wings again. Accordingly, this study investigated whether non-verbal communication factors experienced through interaction with airline flight attendants for passengers who have traveled abroad within the past year through domestic airlines affect customer engagement and brand intimacy. A total of 285 samples were collected, and SPSS 28 and AMOS 26 programs were used to verify the reliability and validity of the research tool, the suitability of the model, and hypotheses. As a result of the empirical study analysis, it was confirmed that Paralanguage and Proxemics in non-verbal communication of flight attendants had a significant effect on customer engagement. Although it is different from the results of previous studies following changes in perspective after COVID-19, it once again confirmed the importance of airline crew communication in providing face-to-face services at the interface with passengers. In order to induce customer engagement, which is a new customer satisfaction management index. In addition, it was confirmed that customer engagement has a significant effect on brand intimacy. These results support the view that it is necessary to establish new customer management indicators of emotion and relationship marketing in the existing marketing centered on price reduction or securing loyalty. It was confirmed that interactions with flight attendants can contribute to customer engagement, and these results have important implications for those working in the air transportation industry.

Moderating Effect of Population Drop in the Relationship Between Demographic Changes and Crime Decline (인구통계학적 구조 변화와 범죄 감소 간의 관계에 있어서 인구 감소의 조절 효과 검증)

  • Soo-Chang Lee;Dae-Chan, Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.3
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    • pp.95-102
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    • 2023
  • This study aims to empirically verify the moderating effect of population drop on the relationship between demographic changes and crime decline in local cities facing population decline in Korea. The study employs changes in the population of young adults, men, elderly, foreign residents, and population movement as factors of demographic changes, including types of the city as a control variable in the research model. The rate of change in population drop is used as a moderator variable and the rate of change in crime decline as a dependent variable. Data are collected from 155 cities with declining populations from 2010 to 2022 through KOSIS, the National Statistics Portal, and information disclosure requests. Data collected are analyzed using moderated regression analysis. In the first and second stages of the analysis, they show that changes in the population of young adults, population movement, foreign people, population drop, and the type of city affect the change in crime. Moderated regression analysis shows that only the interaction terms among changes in the population of young adults, changes in population movement, and changes in the population of foreigners and the population drop affects change in crime significantly.

MoJMJD6, a Nuclear Protein, Regulates Conidial Germination and Appressorium Formation at the Early Stage of Pathogenesis in Magnaporthe oryzae

  • Li Zhang;Dong Li;Min Lu;Zechi Wu;Chaotian Liu;Yingying Shi;Mengyu Zhang;Zhangjie Nan;Weixiang Wang
    • The Plant Pathology Journal
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    • v.39 no.4
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    • pp.361-373
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    • 2023
  • In plant-pathogen interactions, Magnaporthe oryzae causes blast disease on more than 50 species of 14 monocot plants, including important crops such as rice, millet, and most 15 recently wheat. M. oryzae is a model fungus for studying plant-microbe interaction, and the main source for fungal pathogenesis in the field. Here we report that MoJMJD6 is required for conidium germination and appressorium formation in M. oryzae. We obtained MoJMJD6 mutants (ΔMojmjd6) using a target gene replacement strategy. The MoJMD6 deletion mutants were delayed for conidium germination, glycogen, and lipid droplets utilization and consequently had decreased virulence. In the ΔMojmjd6 null mutants, global histone methyltransferase modifications (H3K4me3, H3K9me3, H3K27me3, and H3K36me2/3) of the genome were unaffected. Taken together, our results indicated that MoJMJD6 function as a nuclear protein which plays an important role in conidium germination and appressorium formation in the M. oryzae. Our work provides insights into MoJMJD6-mediated regulation in the early stage of pathogenesis in plant fungi.

A Comparative Study of family gap in Welfare States :The Role of family policy and labor market structure (복지국가의 '자녀유무별 여성임금격차(Family gap)' 비교연구 : 가족정책과 노동시장구조의 영향을 중심으로)

  • Huh, Soo Yeon
    • Korean Journal of Social Welfare Studies
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    • v.41 no.2
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    • pp.279-308
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    • 2010
  • This study examines the association between family policies and family gap using data for 14 OECD countries. As family policies have different assumptions about women's roles and include variant sub-policies, this study identify two distinct family policies: 'employment support policy' to support women as employed workers and 'caregiving support policy' to support women as caregivers. Meanwhile, women's wage cannot be determined by the effect of 'only' family policy. Therefore, analysis model includes variant macro structure supposed to affect women's labor status and wage, like labor market structure, wage structure(compression), women's social status and economic status, and examines interaction effects between family policies and these labor market and social structures using Fuzzy-Set Qualitative Comparative Analysis (FSQCA). The FSQCA result shows that relatively low family gap is associated with the conjunctual causation of developed 'employment support policy' and compressed wage structure.

An Examination of the Effectiveness of Crisis Response Strategies for Repairing Competence and Integrity Violations

  • Sung, Yen-yi;Lee, Han-joon;Park, Jong-chul
    • Asia Marketing Journal
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    • v.15 no.1
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    • pp.129-154
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    • 2013
  • Product-harm crises, which are connected to defective or dangerous products, are perceived as the most common threats to a company. Product harm crises can distort long standing favorable equality perceptions, tarnish a company's reputation, cause major revenue and market-share losses, lead to costly product recalls, and devastate a carefully nurtured brand equity. However, in spite of the devastating impact of product-harm crises, little systematic research exists to asses its marketing consequences. So, the purpose of this study is to investigate how Koreans react to the crisis response in the aftermath of different crises(competence violation vs. integrity violation) and inspire additional research in crisis communication. This study has three main findings which run counter to the assumptions of Kim et al.(2007). Namely, the current study expands on the research of Kim et al. (2004, 2007) by examining how companies repair customers' trust and corporate attitude after crises. Different from previous studies, this study assumes that apology for an integrity-based crisis is the most appropriate way to repair consumer trust and corporate attitude. As for competence-based crisis, similarly, apology for competence-based crisis can be more successful repairing consumer trust and corporate attitude. Concerning silence strategy, remaining silent dose not admit or deny guilt right away, but instead of asking the perceiver to withhold judgment, suggesting that, silence could be expected to be superior to apology but inferior to denial. Finally, apology for competence violation will be expected to bemore effective than apology for integrity violation. Research conceptual model was as follows: According to the results, apology is found to be the most effective strategy to repair corporate attitude no matter the crisis is perceived as a violation of competence or integrity. Second, company may consider keeping silent as a desirable response because they does not admit nor deny responsibility but ask the public to withhold judgment. However, the result of this study shows that, in the overall crisis situations, silence strategy did not differ significantly from the denial strategy, which suggested that the public wants explanation instead of uncertainty. Third, there was the interaction effect between crisis type and crisis response strategies. In this study, apology is more effective for the competence violated situation in terms of regaining consumer trust and repairing their attitude toward company, while the apology's effectiveness is lower for the integrity-violated situation. More specifically, when the crisis is perceived due to company's lack of ability(competence violation), consumer's trust belief and attitude toward the company is more easily to repair when the company issued a sincere apology. Damaged product is perceived less intentional so participants are more likely to give the company second chance when they apology to the public. By contrast, exaggerated advertisement(integrity violation) is perceived intentionally and thus makes participants angrier toward the accused company. Although apology is perceived as the most effective strategy, when issuing apology, it also means the company admitted their intention. Therefore, in this kind of crisis situation, trust repair needs not only a sincere apology but additional efforts.

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Looking into Child-rearing Experience of Mothers from Multicultural Families through the Grounded Theory Paradigm Model (근거이론 패러다임 모형으로 다문화가정 어머니의 자녀양육경험 들여다보기)

  • Oh, Ok Sun ;Kim, Sung Bong
    • Korean Journal of Culture and Social Issue
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    • v.18 no.2
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    • pp.235-260
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    • 2012
  • This study was aimed at looking into and understanding child-rearing experience of mothers from multicultural families based on the grounded theory, one of the qualitative research methods. For this, twelve mothers from multicultural families were selected and data were collected through in-depth interviews with them and then analyzed through the open coding, axial coding and selective coding. The analysis suggested that main phenomena mothers from multicultural families experienced are the conflict of child-rearing and educational crisis, and the confused identity of parenting. These main phenomena had much to do with contextual factors such as economic hardship, lower level of the Korean language, cultural differences, prejudices and ignorance. The severeness of conflict and crisis of child-rearing and the intensity of identity confusion for parenting depended on arbitral conditions such as family bonds, positive expectation for the future of their children, and the help of supportive systems. Mothers were dealing with difficulties of child-rearing through action and interaction of resignation and denial, introspection and the intention to overcome difficulties, and the capacity building. As a result, mothers from multicultural families acknowledged that there is a limit to their position and roles they can play and tried to change in order to resolve problems related to their children, positioning themselves for more active lives in Korean society. Through discussion based on the findings of the study, this study can help better understand child-rearing experience of mothers from multicultural families and suggest several directions for future researches on multicultural families.

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An analysis methodology for the power generation of a solar power plant considering weather, location, and installation conditions (입지 및 설치방식에 따른 태양광 발전량 분석 방법에 관한 연구)

  • Byoung Noh Heo;Jae Hyun Lee
    • Journal of Korea Society of Industrial Information Systems
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    • v.28 no.6
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    • pp.91-98
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    • 2023
  • The amount of power generation of a solar plant has a high correlation with weather conditions, geographical conditions, and the installation conditions of solar panels. Previous studies have found the elements which impacts the amount of power generation. Some of them found the optimal conditions for solar panels to generate the maximum amount of power. Considering the realistic constraints when installing a solar power plant, it is very difficult to satisfy the conditions for the maximum power generation. Therefore, it is necessary to know how sensitive the solar power generation amount is to factors affecting the power generation amount, so that plant owners can predict the amount of solar power generation when examining the installation of a solar power plant. In this study, we propose a polynomial regression analysis method to analyze the relationship between solar power plant's power generation and related factors such as weather, location, and installation conditions. Analysis data were collected from 10 solar power plants installed and operated in Daegu and Gyeongbuk. As a result of the analysis, it was found that the amount of power generation was affected by panel type, amount of insolation and shade. In addition, the power generation was affected by interaction of the installation angle and direction of the panel.

A Case Study on Regional Tourism Innovation through Smart Tourism: Focusing on Incheon Smart Tourism City Project (스마트관광을 활용한 지역관광 혁신사례 연구: 인천 스마트관광도시를 중심으로)

  • Han, Hani;Chung, Namho
    • Knowledge Management Research
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    • v.25 no.1
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    • pp.67-88
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    • 2024
  • Smart tourism aims to maximize the utilization of local tourism resources, effectively manages cities and contributes to improving communication and quality of life between tourists and residents. Therefore, smart tourism emphasizes synergistic collaboration, considering both residents and tourists. This study explores smart tourism interaction and roles in enhancing regional competitiveness. By conducting thorough examination, focusing on integrating the four key elements of smart tourism city (smart experience, smart convenience, smart accessibility, and smart platform) with local residents, local businesses, regional resources, and ecosystem to foster positive synergies, Incheon smart tourism city project was employed as a single case study design. Research results indicate that the collaborative model of a smart tourism city positively impacts service satisfaction and strengthens regional tourism competitiveness. Building upon these results, this study aims to contribute to the development of smart tourism cities by proposing directions for future development and emphasizing the enhancement of regional competitiveness through the integration of smart technology and local tourism.

The Influence of Time to Draw Students' Mental Models and Students' Field Dependence-Independence in Drawing in Relation to Learning with Multiple Representations (다중 표상 학습에 적용한 그리기에서 학생들의 정신 모형을 그리는 시기 및 장의존성.장독립성에 따른 효과)

  • Kang, Hun-Sik;Kwack, Jin-Ha;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.26 no.2
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    • pp.191-199
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    • 2006
  • This study investigated the influence of time to draw students' mental models and students' field dependence-independence on learning the particulate nature of matter with multiple representations. Seventh graders (N=295) at two middle schools were assigned to control, after-drawing, and before-drawing groups. The students learned "Boyle's Law" and "Charles's Law" for two class periods. Results revealed that the scores of a test on conceptual understanding for the two drawing groups were significantly higher than those for the control group. However, there was no significant interaction between the instruction and students' field dependence-independence in the scores of the test on conceptual understanding. In 'novelty' on a situational interest test, field independent students in the two drawing groups scored significantly higher than those in the control group. The scores for field independent students in each group were similar, while field dependent students in the before-drawing group scored lower than those in the control and after-drawing groups in 'attention demand' on the situational interest test. It was found that most students positively perceived after-drawing or before-drawing, but field independent students in the before-drawing group were more apprehensive about the activities than those in the after-drawing group.