• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 1996년도 춘계공동학술대회논문집; 공군사관학교, 청주; 26-27 Apr. 1996
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• pp.407-410
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• 1996

This paper presents how to build a human sensibility database by multivariate method. And, we discribe a fuzzy based inference system which converts human sensibility data to design factors using the human sensibility database. We are able to obtain the values of multiple correlation coeffcient, partial correlation coefficient, and categories by the quantification theory which is multivariate analysis. So, the human sensibility database is constructed from those values. The inference system will be more useful, if the human sensibility database and graphic design factor database were integrated.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 춘계학술발표대회
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• pp.902-904
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• 2010

본 논문에서는 개인 특화된 의료를 위한 진단, 치료선택, 예후 추정을 지원하기 위한 정보를 전문 의료인에게 효과적으로 제공하기 위한 데이터베이스 설계와 구축을 제시한다. 내원 환자들의 유전자 수준의 미시 데이터, 임상학적 거시 데이터, 가족력, 유사 질환군 등의 연관정보 데이터를 통합 연계하여 이력으로 관리하고, 데이터의 점진적 누적이 가능한 통합의료시스템을 위한 데이터베이스 설계의 프레임워크를 구축하였다.

• BMB Reports
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• 제39권4호
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• pp.441-447
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• 2006

Abuse of drugs can elicit compulsive drug seeking behaviors upon repeated administration, and ultimately leads to the phenomenon of addiction. We developed a procedure for the standardization of microarray gene expression data of rat brain in drug addiction and stored them in a single integrated database system, focusing on more effective data processing and interpretation. Another characteristic of the present database is that it has a systematic flexibility for statistical analysis and linking with other databases. Basically, we adopt an intelligent SQL querying system, as the foundation of our DB, in order to set up an interactive module which can automatically read the raw gene expression data in the standardized format. We maximize the usability of this DB, helping users study significant gene expression and identify biological function of the genes through integrated up-to-date gene information such as GO annotation and metabolic pathway. For collecting the latest information of selected gene from the database, we also set up the local BLAST search engine and non-redundant sequence database updated by NCBI server on a daily basis. We find that the present database is a useful query interface and data-mining tool, specifically for finding out the genes related to drug addiction. We apply this system to the identification and characterization of methamphetamine-induced genes' behavior in rat brain.

• Molecular & Cellular Toxicology
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• 제3권3호
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• pp.208-213
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• 2007

With the help of a development and popularization of microarray technology that enable to us to simultaneously investigate the expression pattern of thousands of genes, the toxicogenomics experimenters can interpret the genome-scale interaction between genes exposed in toxicant or toxicant-related environment. The ultimate and primary goal of toxicogenomics identifies functional context among the group of genes that are differentially or similarly coexpressed under the specific toxic substance. On the other side, public reference databases with transcriptom, proteom, and biological pathway information are needed for the analysis of these complex omics data. However, due to the heterogeneous and independent nature of these databases, it is hard to individually analyze a large omics annotations and their pathway information. Fortunately, several web sites of the public database provide information linked to other. Nevertheless it involves not only approriate information but also unnecessary information to users. Therefore, the systematically integrated database that is suitable to a demand of experimenters is needed. For these reasons, we propose SOP (Search of Omics Pathway) database system which is constructed as the integrated biological database converting heterogeneous feature of public databases into combined feature. In addition, SOP offers user-friendly web interfaces which enable users to submit gene queries for biological interpretation of gene lists derived from omics experiments. Outputs of SOP web interface are supported as the omics annotation table and the visualized pathway maps of KEGG PATHWAY database. We believe that SOP will appear as a helpful tool to perform biological interpretation of genes or proteins traced to omics experiments, lead to new discoveries from their pathway analysis, and design new hypothesis for a next toxicogenomics experiments.

• 한국항공우주학회지
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• 제31권5호
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• pp.25-36
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• 2003

항공기 설계는 설계 전 분야에 걸친 설계 요소들을 모두 고려한 통합적 환경에서 이루어 져야 한다. 이를 위해 각 분야간의 데이터 공유 및 일관성, 무결성, 최신성 등이 요구되며 이러한 요구사항을 만족할 수 있는 효율적인 데이터베이스의 설계가 필요하다. 데이터베이스의 설계 순기는 저장되고 관리해야 할 데이터의 분석, E-R Diagram의 작성, 테이블 사상으로 이루어진다. 본 연구에서는 상용의 Oracle 8i 데이터베이스 관리시스템을 이용하여 데이터베이스를 설계, 구축하였다. MDF(MultiDisplinary Feasible), IDF(Individual Discipline Feasible), CO(Collaborative Optimization) 등의 MDO(Multidisciplinary Design Optimization) 기법을 적용할 수 있는 데이터베이스의 설계과정을 정립하고, 간단한 수치예제와 무인전투기 최적화 설계 등의 예제를 통하여 통합환경에서의 데이터베이스 설계 방법의 타당성을 검증하였다.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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• pp.383-387
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• 2005

One of the most important issues in post-genome era is identifying functions of genes and understanding the interaction among them. Such interactions from complex biochemical pathways, which are very useful to understand the organism system. We present an integrated biochemical pathway database system with a set of software tools for reconstruction, visualization, and simulation of the pathways from the database. The novel features of the presented system include: (a) automatic integration of the heterogeneous biochemical pathway databases, (b) gene ontology for high quality of database in the integration and query (c) various biochemical simulations on the pathway database, (d) dynamic pathway reconstruction for the gene list or sequence data, (e) graphical tools which enable users to view the reconstructed pathways in a dynamic form, (f) importing/exporting SBML documents, a data exchange standard for systems biology.

• 한국CDE학회논문집
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• 제6권2호
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• pp.140-146
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• 2001

A nuclear Power Plant is composed of a number of mechanical components. Maintaining the integrity of these components is one of the most critical issues in nuclear industry. In order to evaluate the integrity of these mechanical components, a lot of data are required including inspection data, geometrical data, material properties, etc. Therefore, an effective database system is essential to manage the integrity of nuclear power plant. For this purpose, an internet based virtual reality environment and web database system was proposed. The developed virtual reality environment provides realistic geometrical configurations of mechanical components using VRML (Virtual Reality Modeling Language). The virtual reality environment was linked with the web database, which can manage the required data for the integrity evaluation. The proposed system is able to share the information regarding the integrity evaluation through internet, and thus, will be suitable for an integrated system for the maintenance of mechanical components.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 1999년도 Japanese Journal of Medical Physics
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• pp.312-315
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• 1999

To improve quality and reliability of a multi-institutuonal radiation oncology database and to enhance the results of radiotherapy, we developed software which can generate another software automatically for converting an existed database to an integrated multi-institutional database ROGAD [Radiation Oncology Greater Area Database].

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2001년도 봄 학술발표논문집 Vol.28 No.1 (B)
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• pp.22-24
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• 2001

A new GIS software Spatial Database Engine(SDE) has been developed to integrated with spatial database that combines conventional and spatially related data. As we known well in the traditional relation database system, the query evaluation techniques are a well-researched subject, many useful and efficient algorithms have been proposed, but in the spatial database system, it is a litter difference with the traditionally ones. Based on the Query Graph Model(QGM), we implemented our own query evaulation plan in the SDE, which can deal with the full functionality query statement SELECT-FROM-WHERE_GROUPBY-HAVING, and treat the spatial data and non-spatial data seamlessly. We proposed a novel multi way join algorithm base on nest loop that may be attractive.

• 한국건설관리학회논문집
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• 제5권4호
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• pp.79-86
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• 2004

One of the most difficult tasks in pavement management information systems is establishing the links between performance measures of a structure and the design and construction inputs. In-situ pavement performance can be considered a response variable to many project input variables, such as design, construction, and traffic loading effects. If we are to fully understand the component of pavement performance and specify the inputs through design and construction specifications to achieve that performance we must develop quantitative relationship between input and response variables through a scientific, fully integrated Pavement Performance Analysis System (PPAS). Hence, the objective of this study is to design a database model required for developing an effective database template that will allow analysis of pavement performance measures based on design and construction information linked by location. In order to select the most appropriate database model, a conceptual database model (Entity Relationship Model) and dimensional model, which is believed to be the most effective modeling technique for data warehouse project, are designed and compared. It is believed that other state highway agencies could adopt the proposed design strategy for implementing a PPAS at the discretion of the state highway agencies.