• Title/Summary/Keyword: Institute of Medicine

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External Auditory Canal Atresia with Otitis Media in a Dog

  • Kim, Ah Reum;Han, Changhee;Hwang, Gunha;Kim, Rakhoon;Go, Woohyun;Lee, Ji Yeong;Lee, Jongbong;An, Soyon;Hwang, Tae Sung;Lee, Dongbin;Lee, Jae-Hoon;Lee, Hee Chun
    • Journal of Veterinary Clinics
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    • v.38 no.3
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    • pp.159-162
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    • 2021
  • A 5-year-old, intact male, poodle dog with right external auditory canal obstruction and subaural mass was presented. Physical examination revealed that right external auditory canal opening was absent and right head tilt was identified. Aspiration in right subaural mass revealed a small amount of dark brown exudate. Streptococcus canis and Staphylococcus spp. were identified on the microbial culture. Radiography of the skull was revealed absence of air-filled ear canal at the right external ear canal (EEC) level. Computed tomography (CT) revealed well capsulated, hypoattenuated mass in the right EEC region. On the contrast enhanced CT images, rim enhancement around the mass and ear canal obstruction were identified. Fluid attenuated material filled with right bulla. Mild thickening of the right tympanic bulla wall with mild lytic lesion of the ventral wall were found. Based on the images findings, the case was tentatively diagnosed as right external auditory canal atresia with otitis media. Total ear canal ablation and lateral bulla osteotomy was performed. The entire ear canal was removed, numerous hair in the canal and the thickening wall were founded. Right ear canal was sent for histopathological evaluation and found to otitis externa. The patient was followed up for two weeks and there were no complications. This report described the CT diagnosis of right EEC atresia with otitis media rarely reported in small breed dogs.

Phytochemical Constituents from the Rhizomes of Osmunda japonica Thunb and Their Anti-oxidant Activity

  • Woo, Kyeong wan;Jung, Ja Kyun;Lee, Hyun Joo;Kim, Tae Muk;Kim, Min Suk;Jung, Ho Kyung;An, Byeongkwan;Ham, Seong Ho;Jeon, Byung Hun;Cho, Hyun Woo
    • Natural Product Sciences
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    • v.23 no.3
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    • pp.217-221
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    • 2017
  • Eleven compounds (1-11) were isolated from the rhizomes of Osmunda japonica, and their structures were elucidated based on $^1H$, $^{13}C-NMR$ and LC-IT-TOF MS data. Of these compounds, all compounds (1 - 11) have been previously reported, although five (6 - 9, 11) have not previously been isolated from this plant. The antioxidant activities of isolated compounds (1 - 11) were measured by DPPH and ABTS assays, and compound 10 showed the high antioxidant activity.

A Case of Human Pulmonary Dirofilariasis in a 48-Year-Old Korean Man

  • Kang, Hyo Jae;Park, Young Sik;Lee, Chang-Hoon;Lee, Sang-Min;Yim, Jae-Joon;Yoo, Chul-Gyu;Kim, Young Whan;Han, Sung Koo;Chai, Jong-Yil;Lee, Jinwoo
    • Parasites, Hosts and Diseases
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    • v.51 no.5
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    • pp.569-572
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    • 2013
  • Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea.