• 수면정신생리
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• 제22권1호
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• pp.11-19
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• 2015

목 적 : 폐쇄성 수면무호흡 증후군(obstructive sleep apnea syndrome, 이하 OSAS)의 특징적 임상양상으로 주간졸림이 있다. 주간졸림과 수면무호흡의 심각도가 비례하는지에 대해서는 이론이 있다. 이러한 이론에는 불면증 정도가 두 변수의 상관관계에 영향을 줄 수 있다는 가정하에 본 연구자들은 피츠버그수면질지수(Pittsburgh Sleep Quality Index, 이하 PSQI) 정도가 주간졸림과 수면무호흡의 심각도의 연관관계에 어떠한 영향을 주는 지에 관해 연구하고자 하였다. 방 법 : 임상병력 및 야간수면다원검사(nocturnal polysomnography, 이하 NPSG)를 실시하여 OSAS로 진단된 235명의 남자 환자를 선정하였다. 전체 대상군의 수면 및 기분 관련 자가보고척도, 수면다원검사지수, 인구학적 척도를 조사하고 이들 사이의 단순상관분석을 시행하였다. 이후 전체 대상군을 PSQI가 5 이하인 A군(n = 75)과 5 초과인 B군(n = 160)으로 나누었다. 각 군에서 제어변수로 벡우울척도(Beck depression inventory, 이하 BDI) 및 벡불안척도(Beck anxiety inventory, 이하 BAI)를 설정하고 엡워스졸림척도(Epworth sleepiness scale, 이하 ESS)와 다른 척도들 간의 편상관관계분석을 시행하였다. 마지막으로 A군에서 주간졸림에 영향을 주는 요소를 알아보기 위해 ESS에 대해 다중회귀분석을 시행하였다. 결 과 : 전체 대상군에서 단순상관분석에서는 ESS와 수면무호흡 심각도 지수들인 무호흡-저호흡 지수(apnea-hypopnea index, 이하 AHI ) (r = 0.148, p = 0.023), 무호흡 지수(apnea index, 이하 AI) (r = 0.137, p = 0.036), 저호흡 지수(hypopnea index, 이하 HI) (r = 0.058, p = 0.377), 산소탈포화도지수(oxygen desaturation index, 이하 ODI)(r = 0.149, p = 0.022), 각성 총지수(arousal total index, 이하 ATI) (r = 0.129, p = 0.048) 간에 미약한 상관관계를 보이거나 상관관계가 없었다. A군에서 ESS와 AHI ($r_p=0.313$, p = 0.008), AI ($r_p=0.339$, p = 0.004), ODI ($r_p=0.289$, p = 0.015), ATI ($r_p=0.256$, p = 0.031) 간에 양의 유의한 상관관계를 보였다. B군에서는 ESS와 수면무호흡의 심각도 척도 간에 유의한 상관관계를 보이지 않았다. A군에서 다중회귀분석 결과 ESS에 통계적으로 유의한 영향을 끼치는 요인으로 AI (t = 2.996, p = 0.004), BAI (t = 2.721, p = 0.008)가 있었다. 결 론 : 주간졸림 정도와 수면무호흡 중증도 간의 유의한 연관성은 A군에서만 관찰되었다. 이 결과는 OSAS 환자가 호소하는 주간졸음을 평가할 때 불면 증상에 대해 고려해야 한다는 것을 시사한다.

• Journal of Korean Neurosurgical Society
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• 제63권2호
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• pp.261-267
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• 2020

Objective : We investigated the effect of hypnotics on sleep quality, cognitive function, and depressive mood in patients with insomnia following brain tumor resection. Methods : From patients who underwent brain tumor resection, we recruited 10 patients with insomnia who received hypnotics for more than 1 week during a 3-week follow-up period (insomnia group). We also recruited 12 control patients with brain tumors but without insomnia (control group). We evaluated sleep quality at baseline and 3 weeks later using the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), the Stanford Sleepiness Scale (SSS), and the Epworth Sleepiness Scale (ESS) and investigated cognitive function and depression using the Computerized Neuropsychological Test and the Beck Depression Inventory (BDI). Results : At baseline, SSS, ISI, PSQI, and BDI scores were significantly higher and visual continuous performance test (VCPT) and auditory continuous performance test (ACPT) scores were significantly lower in the insomnia than in the control group. Three weeks later, the patients who had received hypnotics had significantly higher ISI, PSQI, ESS, VCPT, ACPT, visual span forward and backward, and visual recognition test scores, and significantly lower BDI scores. Conclusion : Quality of sleep in patients with insomnia following brain tumor resection was initially poor but improved significantly after taking hypnotic medication. Further, the hypnotic medications appeared to contribute to the amelioration of cognitive impairments and depressive moods in patients who previously underwent brain tumor resection. We thus recommend the use of hypnotics for patients with brain tumors with insomnia.

• 근관절건강학회지
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• 제30권2호
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• pp.129-137
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• 2023

Purpose: The purpose of this study was to investigate the effect of auricular acupressure on insomnia. Methods: Forty-four adults with insomnia for >1 month were recruited and randomly assigned to either the experimental or control group. In the experimental group, acupressure stickers were attached to the areas of Pineal Gland (TG1), Aggressivity point (LO2), Point Zero (HX1), and Occiput (AT3) for 1 week. Sleep hygiene education materials were provided to the control group, but acupressure was not provided. The collected data were analyzed using the SPSS ver. 26 program. Results: As a result of controlling for the severity of insomnia (F=5.40, p=.025) and headache (F=4.60, p=.038), which showed a significant difference in the homogeneity test as covariates, the Pittsburgh Sleep Quality Index score in the experimental group decreased compared to that in the control group . Conclusion: The result of this study showed that auricular acupressure was helpful in improving insomnia.

• 수면정신생리
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• 제30권1호
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• pp.22-27
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• 2023

목 적: 본 연구에서는 불면증상 뿐만 아니라 과다수면, 하지불안증후군을 포함하여 수면 문제를 포괄적으로 평가하기 위한 수면 문제 선별 설문지(Sleep Problem Screening Questionnaire, SPSQ)를 개발하고, 신뢰도와 타당도를 검증하고자 하였다. 방 법: 불면증상(SPSQi), 과다수면(SPSQh), 하지불안증후군(SPSQr)의 세 가지 하위 영역을 포함하는 SPSQ를 개발하였다. 다음으로, 불면장애 임상군 222명 및 건강군 78명을 대상으로 SPSQ와 비교 척도인 불면증 심각도 척도(Korean version of Insomnia Severity Index)를 진행하고, 해당 데이터를 분석에 사용하였다. 결 과: SPSQ는 수용할만한 내적 일관성과 수렴·변별 타당도를 보여 수면장애의 측정에 타당한 도구로 평가되었다. ROC curve 분석 결과, 불면장애의 임상적 유의미성 판단을 위한 절단점은 SPSQi 6점, 민감도와 특이도는 각각 0.94, 0.96이었다. 결 론: 해당 연구결과는 SPSQ가 일반 성인 인구의 수면 문제를 선별하는데 있어 신뢰할 수 있고 유효한 도구임을 시사한다. 단, 하지불안증후군 및 과다수면 관련 척도와 비교 검증이 수행되지 못한 점을 고려해야겠다.

• 동의신경정신과학회지
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• 제27권3호
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• pp.185-196
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• 2016

Objectives: This study was undertaken by the department of Korean neuropsychiatry, to evaluate the effects of M&L psychotherapy and Korean Medical Treatments on hospitalized North Korean defectors.Methods: We treated two patients with indigenous Korean medical therapies (acupuncture and herb-medicine) and M&L psychotherapy. Beck's Depression Inventory (BDI), Insomnia Severity Index (ISI), Geriatric Depression Scale (GDS), Mini-mental state examination Korean Version (MMSE-K), and Visual Analogue Scale (VAS) were used to evaluate the patients.Results: Following observations were made after treatments. Case 1: the patient had significant improvement in Beck's Depression Inventory (BDI), Insomnia Severity Index (ISI), and Visual Analogue Scale (VAS). Case 2: similar improvements were observed. Here, the patient had undergone Geriatric Depression Scale (GDS), Mini-mental state examination Korean Version (MMSE-K), and Visual Analogue Scale (VAS). In addition, noticeable improvement was observed in other accompanying symptoms.Conclusions: These results suggest that M&L Psychotherapy and Korean medical treatments might be effective for treating the psychiatric and physical symptoms of hospitalized North Korean Defectors.

• 동의신경정신과학회지
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• 제34권2호
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• pp.115-124
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• 2023

Objectives: To report the efficacy of using EFT and Korean medicine treatment for ASD induced by a traffic accident. Methods: We treated ASD symptoms with Korean medicine (acupuncture, cupping, interferential current therapy, herbal acupuncture therapy). To evaluate results of this treatment, Korean version of PTSD Checklist-5 (PCL-5-K), Beck Depression Inventory (BDI), Insomnia Severity Index (ISI), and Numeric rating scale (NRS) at first visit, 5 weeks, and 12 weeks were used. Results: Korean version of PTSD Checklist-5 (PCL-5-K), Beck Depression Inventory (BDI), Insomnia Severity Index (ISI), and Numeric rating scale (NRS) showed improvements after treatments. Conclusions: This study suggests that Korean medicine and EFT treatment might be effective for ASD.

• The Korean Journal of Pain
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• 제28권2호
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• pp.137-143
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• 2015

Background: Insomnia is becoming increasingly recognized as a clinically important symptom in patients with chronic low back pain (CLBP). In this retrospective study, we have determined risk factors associated with clinical insomnia in CLBP patients in a university hospital in Korea. Methods: Data from four-hundred and eighty one CLBP patients was analyzed in this study. The Insomnia Severity Index (ISI) was used to determine the presence of clinical insomnia (ISI score ${\geq}15$). Patients' demographics and pain-related factors were evaluated by logistic regression analysis to identify risk factors of clinical insomnia in CLBP. Results: It was found that 43% of patients reported mild to severe insomnia after the development of back pain. In addition, 20% of patients met the criteria for clinically significant insomnia (ISI score ${\geq}15$). In a stepwise multivariate analysis, high pain intensity, the presence of comorbid musculoskeletal pain and neuropathic pain components, and high level of depression were strongly associated with clinical insomnia in CLBP. Among these factors, the presence of comorbid musculoskeletal pain other than back pain was the strongest determinant, with the highest odds ratio of 8.074 (95% CI 4.250 to 15.339) for predicting clinical insomnia. Conclusions: Insomnia should be addressed as an integral part of pain management in CLBP patients with these risk factors, especially in patients suffering from CLBP with comorbid musculoskeletal pain.

• 대한한의정보학회지
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• 제19권2호
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• pp.29-37
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• 2013

Objectives: This case report presents a 29-years-old male patient. His chief complaint was insomnia, anxiety and chest discomfort. We diagnosed him with sleep disorder. During the therapeutic period, he experienced temporary improvement. Methods: We treated him with emotional freedom techniques(EFT), giungoren-therapy. Also, acupuncture and chuna therapy were accessorily practiced. The effects of treatment were measured by Beck depression inventory(BDI), state-trait anxiety inventory(STAI), insomnia severity index(ISI). Results: After treatment, the chief complaint have been subsided and improved. But, BDI, STAI, ISI score were not remarkably decreased. Conclusions: This result suggests that EFT and giungoren-therapy might be effective for sleep disorder patient with anxiety.

• 대한중풍순환신경학회지
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• 제19권1호
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• pp.9-20
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• 2018

■ Objectives The purpose of this case report is to show the effect of Traditional Korean Medicine(TKM) on a patient with insomnia occurred after onset of thalamic hemorrhage. ■ Methods A patient with insomnia diagnosed as thalamic hemorrhage was treated with herbal medication, acupuncture, electro-acupuncture, cupping and moxibustion. Then we evaluated the improvement with the number of times the patient woke up, PSQI-K(Pittsburgh Sleep Quality Index-Korean), ISI-K(Insomnia Severity Index-Korean) and KESS(Korean version of Epworth sleepiness scale). ■ Results Decrease in scores of PSQI-K, ISI-K, KESS and the number of times the patients woke up were observed after the TKM treatment. ■ Conclusion This case showed the effect of TKM treatment on poststroke insomnia.

• 지역사회간호학회지
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• 제24권2호
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• pp.205-213
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• 2013

Purpose: The purpose of this study is to investigate the effects of visiting laughter therapy on depression and insomnia in the vulnerable elderly. Methods: A quasi-experimental nonequivalent control group pretest-posttest design was used for this study. The participants were 87 elderly who were registered in the Tailored Visiting Health Program of public health centers. Data were collected from September to November 2010. The experimental group received visiting laughter therapy froma visiting nurse who had taken laughter training provided by laughter therapy experts. The experimental group received 10~15 min of laughter therapy once a week for 8 weeks. The instruments included Geriatric Depression Scale and Insomnia Severity Index to measure depression and sleep problems before and after the laughter therapy. Results: The results showed that visiting laughter therapy was effective in decreasing depression and insomnia among the vulnerable elderly. Conclusion: These findings indicate that laughter therapy may be an effective nursing intervention to improve depression and insomnia Further studies would be needed to identify the difference of effects according to time, interval, or period of visiting laughter therapy and to evaluate the lasting effect of visiting laughter therapy.