• Korean Journal of Applied Biomechanics
• /
• v.29 no.2
• /
• pp.113-119
• /
• 2019

Objective: The purpose of this study was to investigate the effect of the falls on the center of pressure (CoP) complexity during gait using non-linear approximate entropy (ApEn). Method: 20 elderly women with experience of falling ($age=72.55{\pm}5.42yrs$; $height=154.40{\pm}4.26cm$; $body\;weight=57.40{\pm}6.21kg$; $preferred\;gait\;speed=0.52{\pm}0.17m/s$) and 20 elderly women with no experience of falling ($age=71.90{\pm}2.90yrs$; $height=155.28{\pm}4.73cm$; $body\;weight=56.70{\pm}5.241kg$; $preferred\;gait\;speed=0.56{\pm}0.13m/s$) were recruited for the study. While they were walking at their preferred gait speed on a treadmill (instrumented dual belt treadmills, Bertec, USA) with a force plate CoP data were collected for the 20 strides. The complexity of the CoP was analyzed using the ApEn technique. Results: The ApEn of the medial-lateral CoP in the fallers showed smaller about 16% compared to the non-fallers (p<.05). The ApEn of the antero-posterior CoP of the fallers showed smaller about 12% compared to the non-fallers, but the difference was not statistically significant. Conclusion: Based on the results of this study, the reduction of the medio-lateral CoP complexity in the elderly gait would be an index to determine the potential fall.

• The Journal of Sustainable Design and Educational Environment Research
• /
• v.20 no.2
• /
• pp.22-30
• /
• 2021

According to the OECD's interim report on Korean education analysis held in 2020, the presenter, Andreas Schleicher, director of education for the OECD, said, "Korean students show a lot of fear, anxiety and nervousness about failure", referring to how Korean students feel anxious even if their test scores are good. It is a simple example, but as mentioned in a recent education announcement, it is a common sight among Korean students, and it is easily experienced while receiving education. As Korea has a high level of interest and enthusiasm for nurturing human resources, various methods must be considered and studied, and solutions to current problems, improvements, and directions for development is encouraged to be presented. This paper considered the methods for innovation of a learning space to improve the quality of school education, and systematically analyzed and organized the effects and impacts of providing a green environment among the methods and means. It is hoped that this study can serve as a small solution and play its role in solving the social problems of complex aspects of students presented previously.

• Asian Journal of Innovation and Policy
• /
• v.11 no.1
• /
• pp.1-29
• /
• 2022

Climate action is at the top of the agenda in the international community, as demonstrated at the 2021 G7 Summit and the 2021 UN Climate Summit. Major developed countries are scrambling to make a transition to a green economy and create a new growth momentum. Following the Paris Climate Agreement in 2016, they focus on "carbon neutrality" as an effective means of tackling climate change. The Republic of Korea, a high-carbon economy, submitted its second Nationally Determined Contribution and announced carbon neutrality as a top policy priority. Accordingly, the country increases government budget in research and development (R&D) and science and technology (S&T) policies. Against this backdrop, this study analyzed policies on carbon-neutral S&T and R&D in major advanced countries. The analysis was made by identifying globally pending issues in carbon-neutral policies and climate technology. In addition, focus group interviews were conducted six times with 10 experts to come up with three R&D strategies and action plans for government-funded research institutes to achieve carbon neutrality. To be specific, the following measures were suggested. First, creative and innovative R&D programs are required to solve the problem of carbon emissions. Second, it is necessary to establish carbon neutrality policies and infrastructure which are sustainable to run and manage. Third, it is crucial to promote cooperation in climate technology based on excellence. In conclusion, the strategies proposed in this study are expected to provide directions and implications for policymakers, researchers, and scholars in science and technology to develop effective strategies to achieve national carbon neutrality.

• BMB Reports
• /
• v.55 no.11
• /
• pp.547-552
• /
• 2022

Sorafenib, originally identified as an inhibitor of multiple oncogenic kinases, induces ferroptosis in hepatocellular carcinoma (HCC) cells. Several pathways that mitigate sorafenib-induced ferroptosis confer drug resistance; thus strategies that enhance ferroptosis increase sorafenib efficacy. Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is upregulated in human HCC tissues and plays a role in cancer cell proliferation. The aim of this study was to determine whether inhibition of ERRγ with DN200434, an orally available inverse agonist, can overcome resistance to sorafenib through induction of ferroptosis. Sorafenib-resistant HCC cells were less sensitive to sorafenibinduced ferroptosis and showed significantly higher ERRγ levels than sorafenib-sensitive HCC cells. DN200434 induced lipid peroxidation and ferroptosis in sorafenib-resistant HCC cells. Mechanistically, DN200434 increased mitochondrial ROS generation by reducing glutathione/glutathione disulfide levels, which subsequently reduced mTOR activity and GPX4 levels. DN200434 induced amplification of the antitumor effects of sorafenib was confirmed in a tumor xenograft model. The present results indicate that DN200434 may be a novel therapeutic strategy to re-sensitize HCC cells to sorafenib.

• Journal of Preventive Medicine and Public Health
• /
• v.34 no.4
• /
• pp.399-407
• /
• 2001

Objectives : To investigate the current status of hospital-based health promotion programs in Korea and to elucidate the factors which affect to the process of implementation. Methods : We conducted a mail survey of all 875 hospitals in Korea from March to May 2001. In reference to 12 specific kinds of health promotion programs, hospital CEOs were asked whether their hospital have such programs, whether they are fully staffed and whether the program is paid for by the patients. Contextual factors(location, hospital type, number of beds, length of operation, public/private status, economic level of the community, the level of competition) and organizational factors (the extent of market, compatibility with vision, formalization), strategic types of the CEOs (defender/analyser/prospector) were also surveyed. The relationships between each variable and the implementation of health promotion services, activation of services, and the target groups(patient/community resident) were analyzed by univariate analysis and the independent effects of these variables were examined with multiple logistic regression. Results : 100 of 125 hospitals responding (84.8%) had mere than one health promotion program. However, they showed fluctuations in the adoption rate of each programs, meaning that comprehensive health promotion services were not provided. Many programs were not fully staffed and few hospitals had paid programs. In factors affecting health promotion service implementation, private hospitals showed a higher rate in implementation than public hospitals. In contrast, when the competition among nearby hospitals was intense, the level of implementation of service lowered. In the strategic type of the CEOs, the prospectors were shown to have instituted more health promotion programs in their hospitals and the analysers had a greater tendency to have programs for community residents than the defenders. Conclusion . Considering the above results, contextual factors may contribute greatly to the introduction of health promotion services in Korean hospital, although the CEO's personal preference and organizational factors play a larger role in the activation of services. Additionally, the CEO's personal preference may be the major influencing factor in the introduction of programs for community residents.

• The Korean Journal of Community Living Science
• /
• v.20 no.1
• /
• pp.61-69
• /
• 2009

This study was conducted to examine the chemical composition of kiwifruit skin, and to est its anti-microbial activities and cytotoxicities, thus, exploring ways for the economic utilization of kiwifruit skin. Four varieties of kiwifruit were examined: Daeheung, Bidan, Haegeum No.1 and Hayward. Vitamin C content in the fruit skins of Bidan, Daeheung, Haegeum No.1 and Hayward were 72.44, 67.22, 62.51 and 61.44mg/100g, respectively. Total amino acids content in the fruit skins of Bidan, Haegeum No.1, Hayward and Daeheung ere 808.31, 706.02, 629.07 and 464.83mg/100g dry weight, respectively. K and Ca content ere $17.20-45.70{\mu}g/mL$ and $4.58-10.15{\mu}g/mL$. While, other inorganic matter contents were below $4.89{\mu}g/mL$. Anti-microbial activity of kiwifruit skin extracts, in terms of the diameter of inhibition zone when tested against five gram positive and three gram negative microbial trains (even in the concentration of 2,000mg/L), was less than 14.1mm. The hyperplasia inhibition of lung cancer cells by methanol extracts from Bidan and Haegeum No.1 using concentrations of 800mg/L were 27.7% and 14.5%, however, those from Daeheung and Hayward were below 3% Consequently, it will be useful to know that kiwifruit skin can be added to processed goods which demand for higher concentrations of vitamin C, amino acids, K and Ca.

• Korean Journal of Community Nutrition
• /
• v.12 no.6
• /
• pp.773-781
• /
• 2007

The objective of this study was to investigate the nutritional and health status of women industrial workers by working fields. One hundred forty eight (105 lead and 43 office) workers were recruited from March 2005 to October 2005. Information on age, education, smoking and drinking status were collected using questionnaire and nutrient intake and diet quality of workers were assessed by average of two-day 24 hr recall method. Biochemical indexes including blood lead level (PbB), indexes for iron status, serum calcium (Ca) and serum lipid profiles were analyzed from fasting venous blood or serum. Results showed that education level of lead workers was lower than that of office workers (p<0.05), but nutrient intake levels were not significantly different by working fields. Overall nutritional status of the subject were good except for calcium, vitamin $B_2$, C and folic acid intakes. PbB of lead workers were significantly higher than that of office workers while mean corpuscular hemoglobin concentration (MCHC) and serum Ca levels were significantly lower in lead workers. MCHC was positively correlated with zinc intake (r=0.166) and serum Ca was positively correlated with vitamin C intake (r=0.179). This study confirms that lead workers need extra care to keep their health and nutritional management especially for the nutrients known to interact with lead. Tailored nutrition education for workers at specific working fields needs to be more focused for the improvement of health status of industrial workers.

• The Korean Journal of Community Living Science
• /
• v.20 no.2
• /
• pp.181-191
• /
• 2009

This study was conducted to examine the distribution status, the physicochemical composition, and the physiological activity of Spergularia marina grown in the western region in Jeon-Ra-Nam-Do, looking for its potential as a local specialty goods. The amount sold of Spergularia marina to different areas from a rural market place was examined during April, 2008. The proportions of Spergularia marina are as follows; Yeongam(30.5%), Muan(24.3%), Naju(20.3%), Hampyeong(18.0%), and Haenam(7.0%), which were shown higher than those of Pimpinella brachycarpa. Total vitamin C and total chlorophyll contents in Spergularia marina were 68.61mg/100g DW and 58.11mg/g DW, respectively. Total amino acid contents were 331.94mg/100g DW and 20 kinds of amino acids were separated and classified. The contents of inorganic matters in Spergularia marina were as follows; Na(64.23mg/L), Mg(15.88mg/L) K(9.99mg/L), Ca(3.83mg/L). The total phenol and the total flavonoid contents of methanol extracts from Spergularia marina were 41.7mg/L and 18.9mg/L, respectively, with an extracting concentration of 2,000mg/L. The nitrite scavenging activity was highest (83.4%) in hot water extract. These results may be useful as basic data for using Spergularia marina as a local specialty goods.

• The Korean Journal of Community Living Science
• /
• v.20 no.4
• /
• pp.549-558
• /
• 2009

This study examined the basic information on the native pear c.v. 'Baekwoon' grown in Mt. Baekwoonsan, Gwangyang, to develop as a local specialty product. the sensory characteristics, chemical compositions, and physiological activities of 'Baekwoon' pear were examined and compared with those of 'Niitaka' pear. Hardness of 'Baekwoon' pear was 19.30N, which was higher than 'Niitaka'. The sugar content of 'Baekwoon' was 11.5 $^{\circ}Brix$, which was lower than 'Niitaka'. The total amino acid contents of the fruit skin and flesh of 'Baekwoon' were 222 mg/100g dry weight (DW) and 130 mg/100g DW, respectively, which were much higher than those of 'Niitaka'. Especially, serine contents in fruit skin and flesh of 'Baekwoon' were 75.4 mg/100g DW and 40.2 mg/100g DW, respectively, which were significantly (p<0.05) higher than those of 'Niitaka'. However, physiological activities, such as total phenol content, DPPH radical scavenging activity, total flavonoid content and nitrite scavenging activity, of 'Baekwoon' were lower than or similar to those of 'Niitaka'. Consequently, vitamin and amino acid contents of 'Baekwoon' were better than those of 'Niitaka'. It is suggested to use fruit skin because of its good composition and physiological activities so that it helps to improve the quality and the biological activity.

• Journal of Internet of Things and Convergence
• /
• v.4 no.1
• /
• pp.23-29
• /
• 2018

The purpose of study was to analyze the trends of 2005 to 2018 revised 'convergence technology research' through text network analysis using NetMiner4.0 program. Data analysis was conducted by using keyword analysis, centrality analysis of 653 authors' keyword from 177 journals. The results of the study are as follows. First, Research on Converging Technology has been studied steadily over the past 13 years in Department of Industry Convergence. Second, the results of the search term frequency analysis show that the 'convergence technology', 'technology convergence', 'convergence', 'design', 'convergence education', 'STEAM', 'convergence research' were used as the main keywords of convergence technology research. Third, Community analysis results show that five communities have been classified five categories according to the characteristics of the search terms 'only IT', 'Cultural industry utilizing Convergence contents', 'Technology innovation and research analysis' And patent development'. Based on these results, we proposed the future directions of convergence technology research.