• The Journal of Asian Finance, Economics and Business
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• v.8 no.4
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• pp.307-315
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• 2021

The study aims to investigate the relationship between innovation activities and business process performance in higher education institution (hereinafter referred to as "HEI") context. The data was collected using a survey and later analyzed through Partial Least Squares Structural Equation Modelling (PLSSEM) and SmartPLS software. A total of 50 questionnaires were submitted from respondents representing vocational study program management located in Makassar, Indonesia. The findings show that two hypotheses discussed in this study fit the empirical data. Specifically, the results show that there is a positive relationship between innovation activities and business process performance, involving two types of innovation activities, which are exploration activities and exploitation activities, within HEIs. Explorative activity is firmly related to exploitative activity, which furthermore links to business process performance within the HEIs observed. The results confirm that exploration activity can stimulate and lead the HEIs management to generate exploitation activity. For instance, capabilities to absorb knowledge from the external institution may lead this institution to generate advanced academic processes, as well as more efficient and effective managerial processes. The study also signifies ambidexterity capacity, suggesting that it may lead HEIs management to formulate proper strategies in achieving better performance and gaining competitive advantage.

• Journal of Technology Innovation
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• v.29 no.4
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• pp.31-57
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• 2021

This study explores the effect of open innovation activities on innovation performance by dividing into two dimensions of breadth and depth of open innovation activity, and it also verifies the mediating effect of technical protection between open innovation activities and innovation performance. In order to examine the hypothesis, it has surveyed 1,403 companies of manufacturing and service with experience in producing innovative results. The results find that the breadth of open innovation activities has a positive effect on the achievement of radical innovation, and the depth of open innovation activities brings a positive effect on the achievement of incremental innovation. The verification result of the mediating effect of technology protection indicates that partially mediated between the breadth of innovation activities and radical innovation activities, and in the case of the depth, it is completely mediated. The results of this study provide the crucial implications not only for the company promoting open innovation, but especially also for the companies promoting product innovation by acquiring technology.

• Journal of the Korean Regional Science Association
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• v.31 no.4
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• pp.107-128
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• 2015

Technology innovation is a competitive weapon of sustainable economic growth at the urban and regional level and the growth of firms. In this study, we empirically investigate the effects of collaborative R&D activity on product innovative outputs and process innovative outputs in manufacturing firms in Korea. We analyze the links between collaborative R&D activity and two types of innovative outputs using an alternative negative binomial regression model. The major finding is that collaborative R&D activity has significant positive effects on both product and process innovation. The results also identify a positive link between all types of innovative outputs and other R&D activities including internal R&D activity, patent activity, external technology and capital goods acquisitions. To induce corporate growth that enhances the productivity of individual firms and produces prolonged economic growth, policy makers should place greater emphasis on creating effective arrangements to promote establishing collaborative R&D strategies for manufacturing firms.

• Journal of Microbiology and Biotechnology
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• v.32 no.8
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• pp.960-966
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• 2022

Lactic acid bacteria (LAB) exert antagonistic activity against root-knot nematodes, mainly by producing organic acids via carbohydrate fermentation. However, they have not yet been used for root-knot nematode (Meloidogyne incognita) control owing to a lack of economic feasibility and effectiveness. In this study, we aimed to isolate organic acid-producing LAB from kimchi (Korean traditional fermented cabbage) and evaluated their nematicidal activity. Among the 234 strains isolated, those showing the highest nematicidal activity were selected and identified as Lactiplantibacillus plantarum WiKim0090. Nematicidal activity and egg hatch inhibitory activity of WiKim0090 culture filtrate were dose dependent. Nematode mortality 3 days after treatment with 2.5% of the culture filtrate was 100%, with a 50% lethal concentration of 1.41%. In pot tests, the inhibitory activity of an L. plantarum WiKim0090-copper sulfate mixture on gall formation increased. Compared to abamectin application, which is a commercial nematicide, a higher control value was observed using the WiKim0090-copper sulfate mixture, indicating that this combination can be effective in controlling the root-knot nematode.

• International Journal of Computer Science & Network Security
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• v.21 no.12spc
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• pp.495-502
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• 2021

The study is devoted to substantiation of directions of intensification of development of small innovative enterprise, which has a significant impact on the overall innovation activity of the country and promotes innovative development, transition to more advanced technological systems. The outlined role of small business in innovative development in the direction of intensifying innovation in the economy, improving organization and production, as well as in the form of direct participation in the innovation process, production of science-intensive products, stimulating demand for innovation. A group of factors hindering the development of small innovative entrepreneurship was identified, including: financial aspects of the activity, shortcomings of organizational and communicative nature, underdeveloped technology market, information plan problems, internal production problems of small business, market problems. The directions of intensification of the development of small innovative entrepreneurship are substantiated, namely: financial and credit support of small innovative entrepreneurship; introduction of tax incentives; material and technical support; nationwide intensification of innovation activity; information support; development of innovation infrastructure. The involvement of the outlined directions of intensification of small innovative entrepreneurship will help to obtain a synergistic effect of innovative development of both small innovative business structures and the economy as a whole.

• Journal of Korea Technology Innovation Society
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• v.21 no.1
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• pp.92-129
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• 2018

In general, a technology and innovation strategy has been established first. Then, the technology and innovation activities are conducted accordingly. The literature on the technology management process points out that the technology and innovation activities exist in some sequences, nonlinear or linear pattern. However, it is also argued that a certain technology and innovation activity can be occurred or disappeared at certain timing. In this paper, it has been analyzed and clarified how the technology and innovation activities are performed and working together with the technology and innovation strategies in certain context especially when the handset market moves from feature phone to smartphone during a last decade. Empirical results show that the starting point of the technology and innovation activity changes according to the technology and innovation strategies. And, technology innovation activities exhibit multi-layer architecture types. It is confirmed that technology and innovation activities follow a specific pattern. However, if there are some changes in the technology and innovation strategy due to the external environment change, some technology and innovation activities can be skipped because the priority of the technology and innovation activities would be changed. If the firm which has the strategy type of 'innovators' fails to adapt to the fast changing external environment and has the inadequate technology and innovation activities, it is required to change the technology and innovation strategy. It will have a huge impact on the firm's survival.

• Journal of Distribution Science
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• v.21 no.12
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• pp.1-13
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• 2023

Purpose: the study aims to examine the impact of ICT on the formation of digital hubs in regions of Kazakhstan, specifically the influence of ICT costs on the level of innovation activity of enterprises, the number of its actors as legal entities by size and region, small and medium enterprises, universities and research and development organisations. Research design, data and methodology: the research methodology is based on the collection of secondary data from the official statistical yearbooks of the Bureau of National Statistics of the Republic of Kazakhstan and the use of quantitative methods, in particular, correlation analysis and multiple regression. Five indicators related to the formation of digital hubs in the regions of the country were selected. Results: the study revealed that ICT spending has an impact on the formation of digital hubs in regions, in particular on the development of the number of legitimate enterprises, SMEs and R&D organisations as actors in digital hubs. A positive dynamic in the growth of the number of actors is visible. However, the hypotheses on the impact of ICT costs on the number of universities and the level of innovation activity were not supported. Conclusions: based on the results of the study, recommendations such as government proposals on strategy development, funding projects of innovation and digital hubs, and business proposals on engaging local entities in digital transformation for the formation of digital hubs in the country's regions have been developed.

• Korean Journal of Microbiology
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• v.38 no.4
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• pp.255-255
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• 2002

For rapid and sensitive measurement of antiviral activities, application of a recombinant virus containing firefly luciferase gene was attempted. Recombinant human cytomegalovirus (HCMV) containing luciferase gene driven by HCMV late gene pp28 promoter (HCMV/pp28-luc) was used to test the antiviral activities of three known compounds and the result was compared with results from the conventional plaque assay for measuring the production of infectious viruses. When human fibroblast cells were infected with HCMV/pp28-luc, luciferase activity was observed at 2 days after infection and reached maximum at 6 days after infection, whereas the production of infectious virus was maximal at 4 days after infection. The antiviral activities of ganciclovir, acyclovir, and papaverine were measured in HFF cells infected with HCMV/PP28-luc and the luciferase activity was compared with the infectious virus titers. Luciferase activity decreased as the concentration of ganciclovir or papaverine increased, while there was a slight decrease in luciferase activity with acyclovir. The level of the decrease in Luciferase activity was comparable to the level of decrease in the production of infectious virus. Therefore, the antiviral assay using recombinant virus HCMV/pp28-luc resulted in sensitivity similar to the conventional plaque assay with a significant reduction in assay time.

• The Journal of the Korea Contents Association
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• v.21 no.4
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• pp.404-413
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• 2021

Small and medium sized firms(SMFs) would form the technology cooperation network with external firms and institutions of owning a variety of technology and knowledge, and according to resource based theory, forming cooperation network is another resource in uncertain business environment. Unlike the related studies, this study examined the effect of individual cooperation activity on innovation performance for SMFs located in Taegu region, and investigated the moderating effect of technology capability in the relationships between individual cooperation activity and innovation performance. In the empirical results, only cooperation research development positively affected innovation performance, and technology capability moderated the relationships between individual cooperation activity and innovation performance. The empirical findings imply that SMFs should do cooperation research development as an intangible asset to overcome the obstacle of development resulted from limited resources, and that SMFs should increase the impact of individual cooperation activity as promoting technology capability.

• Natural Product Sciences
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• v.13 no.2
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• pp.144-147
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• 2007

Using antifungal activity-guided fractionation, an actinomycete, Streptomyces padanus strain TH-04, which was isolated from mummified peaches infected with Monilinia fructicola, was found to produce the valinomycin (1). The structure of 1 was established using spectroscopic data, which including one- and two-dimensional NMR experimental and mass spectroscopy. Valinomycin (1) showed antifungal activity against Phytophthora capsici, with an IC$_{50}$ value of 15.9 ${\mu}$g/mL.