• Archives of Plastic Surgery
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• v.45 no.6
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• pp.598.1-598.1
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• 2018

• Journal of Sensor Science and Technology
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• v.24 no.6
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• pp.373-378
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• 2015

The structure of the human ear is divided into the outer ear, the middle ear, and the inner ear. The inner ear includes the cochlea that plays a very important role in hearing. Recently, the development of an artificial cochlear device for the hearing impaired with cochlear damage has been actively researched. Research has been carried out on the biomimetic piezoelectric thin film ABM (Artificial Basilar Membrane) in particular. In an effort to improve the frequency separation performance of the existing piezoelectric thin film ABM, this paper presents the design, fabrication, and characterization of the production and performance of a partially etched-type ABM material. $O_2$ plasma etching equipment was used to partially etch a piezoelectric thin film ABM to make it more flexible. The mechanical-behavior characterization of the manufactured partially etched-type ABM showed that the overall separation frequency range shifted to a lower frequency range more suitable for audible frequency bandwidths and it displayed an improved frequency separation performance. In addition, the maximum magnitude of the vibration displacement at the first local resonant frequency was enhanced by three times from 38 nm to 112 nm. It is expected that the newly designed, partially etched-type ABM will improve the issue of cross-talk between nearby electrodes and that the manufactured partially etched-type ABM will be utilized for next-generation ABM research.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.2
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• pp.23-42
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• 2020

Objectives : This study is designed to analyze the outpatients who received medical treatments for ear diseases in ophthalmology & otolaryngology & dermatology clinic of Daejeon Korean Medical Hospital from March, 2013 to February, 2019. Methods : We classified the otology outpatients who received medical treatments in ophthalmology & otolaryngology & dermatology clinic of Daejeon Korean Medical Hospital from March, 2012 to February, 2019 according to gender, year, age, season, anatomical parts, and main diagnosis. The statistical analysis was performed using SPSS 25.0. Results : 1. The number of outpatients with ear diseases were 880; 505 female and 375 male. The number of female patients were approximately 1.7 times higher. 2. The average age of the outpatients with ear diseases were 50.0. The number of middle-aged (40-50s) patients were 439, which is almost half the number(49.9%) of the whole patients. 3. By analyzing the number of patients classified by year, we found out that the number of the outpatients with ear diseases has increased gradually for the past 7 years. 4. In the analysis of the number of patients classified by the anatomical parts of the ear, the inner ear diseases group were the largest, amounting to 79.3% of the whole patients. 5. In the analysis of the number of patients classified by main diagnosis, Tinnitus turns out to be the largest group with 338 patients, followed by sudden sensorineural hearing loss, dizziness, otalgia, Meniere's syndrome, otitis, auditory tube dysfunction, BPPV. 6. No statistical-significant difference were shown in the analysis of the number of patients classified by season. Conclusions : It turns out that patients with ear diseases had increased by the years, and middle aged patients (40-50s) were the largest among the age groups. Most of the patients came for the inner-ear diseases, and tinnitus, sudden sensorineural hearing loss took up the largest proportions.

• Journal of Veterinary Clinics
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• v.36 no.5
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• pp.266-270
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• 2019

A 13-year-old spayed female American cocker spaniel dog was submitted to an animal hospital with a mass from left ear canal and enlarged left parotid lymph node. Given one-year history of odorous exudates and chronic otitis externa, total ear canal ablation was performed. Grossly, because of the neoplastic mass in both inner and outside of annular cartilage in external ear, vertical ear canal was severely narrowed. Histologically, there were numerous proliferated glands in the ear canal mass. Many neoplastic glands contained secretory vesicles on the free margin and necrotic cellular debris. Severe multifocal necrosis and strong invasion were also observed throughout the mass. Massive metastatic foci of glandular structures originated from ceruminous gland were presented in the enlarged parotid lymph node. Neoplastic glandular epithelia contained PAS-positive diastase-resistant eosinophilic cytoplasmic granules. Immunohistochemically, the neoplastic cells showed positive reactions for cytokeratin (CK) 7 and negative for CK 5/6. Based on the clinical implication and gross findings, histopathology and immunohistochemistry, this case was diagnosed as metastatic ceruminous gland adenocarcinoma in the American cocker spaniel.

• Proceedings of the KIEE Conference
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• 1987.07b
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• pp.1322-1325
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• 1987

In this study, the excitation pattern, which can be sensated by a man having hearing loss due to the damage of inner ear, is extracted, and the procedure of the auditory speech signal processing is simulated with the computer. Therefore, the excitation pattern is extracted by the neural tuning model satisfying the physiological characteristic of the inner ear and by the infor.ation extracted from speech signal. The firing pattern is also extracted by inputting this excitation pattern to the auditory neural model. With this extracted firing pattern, the possibility that the patient can sensate the speech signal is studied by the computer simulation.

• Medical Lasers
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• v.9 no.1
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• pp.1-5
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• 2020

Hearing organs have unique characteristics and have a role in processing external sensory signals. Sensory hair cells and nerve fibers in the organ of Corti can be damaged by various causes and they do not regenerate themselves. Medication used for clinical treatment for the inner ear is limited due to the anatomical structure of the inner ear. Photobiomodulation (PBM) is a therapeutic approach that uses various sources of light and the success of PBM therapy is highly reliant on the parameters of the light sources. The positive effects of PBM have been reported in various clinical fields. This paper summarizes the previously reported research on PBM for the treatment of hearing damage in animal models.

• Phonetics and Speech Sciences
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• v.1 no.4
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• pp.203-207
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• 2009

Electrically evoked compound action potentials (ECAP) have originated from the distal end of the auditory nerve. ECAP are characterized as the difference between the clearly large trough (N) and the following positive peak (P). N-wave occurs around $200-400\;{\mu}s$ after stimulus onset and P-wave at around $400-800\;{\mu}s$. Contrary to expectations, positive peaked ECAP (pp-ECAP) was dominated by a relatively large-amplitude positive following negative peak. pp-ECAP can be recorded from the sites on or near the surgically exposed nerve trunk in animal models and/or in cases of monophasic stimulation. This study will provide the causes of the appearance of pp-ECAP in cases of cochlear implant recipients using imaging studies and medical records and statistically analysis between N-P and P-N on the amplitude input-output function (amp-I/O) for the prediction of the possibilities of clinical tools. Thirteen children participated in the study and received a Cochlear CI-24RE (CA). ECAP was recorded using auto-NRT (Cochlear Ltd., Australia) at four to five weeks post surgery. pp-ECAP was measured from 36 electrodes and typical ECAP from 220 electrodes. There was no abnormality in the imaging study and operation finding in patients with typical ECAP. pp-ECAP was found at the inner ear anormaly and ossification in imaging study and gel-state inner ear fluid was observed in the operation finding. The amplitude of pp-ECAP increased depending on current intensities, but amp-I/O increase more gradually than in the case of typical ECAP (p=0.003). pp-ECAP is antidromic potential which can record from the inner ear anormaly and ossified cochlear. Amp-I/O also depends on current intensity as well typical ECAP. These results provide a useful tool for audiological evaluation for the spiral ganglion cell status to the value of pp-ECAP.

• Proceedings of the KIEE Conference
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• 2001.07d
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• pp.2567-2569
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• 2001

본 논문에서는 내이(Inner ear)의 한 부분을 차지하는 Inner Hair Cell을 구현함에 있어 필수적인 요소인 낮은 극점을 갖는 저역통과필터(LPF)를 최소의 면적으로 구현하기 위한 설계방법을 언급한다. 이를 위해 본 논문에서는 CMOS Compatible Lateral BJT (CLBT)를 사용하여 능동소자의 등가 저항을 증가시켜 커패시터의 값을 획기적으로 줄일 수 있는 기법의 LPF와 gm-C필터를 이용한 LPF를 전류모드로 설계하였다. 저전력 특성과 큰 임피던스 특성을 얻기 위해 모든 트랜지스터는 약반전 영역에서 동작하고 극점은 1kHz근처에 존재한다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.37.2-38
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• 1981

Recently the efficacy of all ear drops in perforated tympanic membranes has been questioned and the safety of using the drugs intratympanically has been challanged. Many drugs not normally ototoxic when given systemically become ototoxic when administered via the middle ear. According to Stupp and others (1973) among neomycin, polymyxin-G, gentamycin, erythr omycin, tetracycline and penicillin, only penicillin was found to be free of toxic effects. The ototoxic antibiotics probably reach the inner ear by permeating the round window membrane, into the perilymph and then through Reissner's membrane to the endolymph. The main pathological changes are degeneration of stria vascularis, degeneration of sensory epithelia and degeneration of ganglion cells. We report with reference, a case of profound sensorineural deafness following the application of Terramycin powder intratympanically, in a 63 year old woman.

• Anatomy and Cell Biology
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• v.55 no.2
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• pp.113-117
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• 2022

The tensor tympani muscle is structurally important in the middle ear, specifically through its involvement in the impedance of sound in response to intense auditory and non-auditory stimuli. Despite numerous studies, its true function has been debated for many years; questions still remain about its role in auditory and non-auditory reflexes and in sound damping. Some studies suggest that the tensor tympani muscle contracts as a result of non-auditory stimulation such as facial or head movements; others suggest that it contracts due to input from the cochlear nucleus, therefore by way of auditory stimulation. Whatever the cause, contraction of the tensor tympani muscle results in low frequency mixed hearing loss, either to protect the inner ear from loud sounds or to desensitize the ear to self-generated sounds. A review of these studies indicated that the tensor tympani muscle has a wide range of functions, yet the mechanisms of some of them have not been clearly demonstrated. One major question is whether the tensor tympani muscle contributes to sound damping; and if it does, what specific role it serves. The primary purpose of this review article is to explore the functions of the tensor tympani muscle in light of recent research advances.