• Journal of the Korea Convergence Society
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• v.11 no.9
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• pp.243-260
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• 2020

The purpose of this study is to analyze measures to promote a private finance initiative aimed at public facility regeneration in the midst of sharp increase in local financial burden due to the low birthrate and rapidly aging population. In particular, the study looked at the case of promoting a private finance initiative through a local platform aimed at public facility regeneration in Narashino, Japan. The study is based on the relevant systems and policies, and government documents and statistical data on the Narashino case. The results show that the local platform helps the local government and participants share business expertise and experiences, leading to improvements in their expertise and business capability. The local platform allows them to identify and discuss potential business ideas in advance, which in turn encourages private investment business.

• Safety and Health at Work
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• v.9 no.3
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• pp.308-313
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• 2018

Background: A behavior-based safety initiative card-issuing system was introduced at a cement-manufacturing company in Zimbabwe in 2008 to try and curb accident occurrence. The purpose of this study was to evaluate the effectiveness of the Behaviour Based Safety Initiative card system as a tool used for reducing accident frequencies. Methods: A mixed-method approach that involving administering piloted questionnaires to 40 out of 244 randomly selected employees, making observations, and reviewing secondary data were done to collect data from different sources in the organization in 2013. A paired t-test was conducted to test whether there was significant difference in accident occurrence before and after the implementation of the BBSI. Scatterplots were also used to establish the correlation between the issuance of cards and the accident and injury occurrence. Results: The findings suggest that the introduction of the card system brought a significant decrease in accident and injury occurrence. A negative correlation between card issuance and accident occurrence was observed, i.e., the greater the number of cards issued, the fewer the number of accidents. It was also noted that the card system positively influenced the mindset of workers towards safe work practices. Conclusion: The card system had an influence on the reduction of accidents and injuries. The organization should leverage on issuing more cards to further reduce the number of accidents and injuries to zero.

• Integrative Medicine Research
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• v.5 no.3
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• pp.223-223
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• 2016

Background: Korean Red Ginseng (Panax ginseng) has been shown to exert antihypertensive effects. In particular, ginsenoside Rg3 is thought to be a potent modulator of vascular function. The present study was performed to examine the antihypertensive efficacy of Korean Red Ginseng (KRG) extract and Rg3-enriched KRG (REKRG) extract. Methods: Spontaneously hypertensive rats (SHRs) andWistar-Kyoto rats (WKYs) were divided into six groups (WKY control, WKY-KRG, WKY-REKRG, SHR control, SHR-KRG, and SHRREKRG), and systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at the carotid artery, followed by injection of 3mg/kg KRG or 3mg/kg REKRG. Results: REKRG treatment significantly decreased SBP and DBP 3hours post-treatment in the SHR group compared with SHR control group. However, SBP and DBP were not significantly different in KRG-treated SHRs compared with control SHRs. REKRG treatment did not significantly alter SBP or DBP 3hours post-treatment in the WKY group compared with WKY control group. Similarly, there were no differences in SBP or DBP with KRG treatment in the WKY group and WKY control group. Both KRG and REKRG increased endothelial nitric oxide synthase phosphorylation levels in the aorta, and the increases in endothelial nitric oxide synthase phosphorylation levels by REKRG treatment were higher than those with KRG treatment. Similarly, nitric oxide production in plasma from WKYs and SHRs was also increased by both KRG and REKRG. Conclusion: These results suggest that REKRG has a more beneficial effect on blood pressure control than KRG in SHRs.

• Journal of Convergence for Information Technology
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• v.11 no.1
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• pp.1-11
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• 2021

This study focuses on that, unlike evolving smart technology, goals, policies, and administrative organization elements are tools that do not change in smart city implementation, and by applying the concept of policy implemental means, the characteristics of the Singapore Smart Nation Initiative are analyzed, results are derived and implications are suggested. To this end, literature analysis is conducted based on the case analysis framework with "Smart Nation" as an analysis unit and "project, administration, citizen engagement" as analysis elements. The implications through analysis are as follows. First, it is required to establish a state-led initiative for a major transformation into a digital society. Second, it is necessary to establish executive agencies directly under the president or prime minister for effective implementation of the initiative. Third, complementary programs at the level of detailed strategies, administrative organizations, and citizen participation as a means of implementation, should be considered and the flow of the recent digital ecosystem should be reflected. Fourth, it is necessary to promote a national movement for a great transformation into a digital society where all the people participate.

• International Journal of Stem Cells
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• v.17 no.2
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• pp.102-112
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• 2024

An organoid is a self-organized three-dimensional structure derived from stem cells that mimics the structure, cell composition, and functional characteristics of specific organs and tissues and is used for evaluating the safety and effectiveness of drugs and the toxicity of industrial chemicals. Organoid technology is a new methodology that could replace testing on animals testing and accelerate development of precision and regenerative medicine. However, large variations in production can occur between laboratories with low reproducibility of the production process and no internationally agreed standards for quality evaluation factors at endpoints. To overcome these barriers that hinder the regulatory acceptance and commercialization of organoids, Korea established the Organoid Standards Initiative in September 2023 with various stakeholders, including industry, academia, regulatory agencies, and standard development experts, through public and private partnerships. This developed general guidelines for organoid manufacturing and quality evaluation and for quality evaluation guidelines for organoid-specific manufacturing for the liver, intestines, and heart through extensive evidence analysis and consensus among experts. This report is based on the common standard guideline v1.0, which is a general organoid manufacturing and quality evaluation to promote the practical use of organoids. This guideline does not focus on specific organoids or specific contexts of use but provides guidance to organoid makers and users on materials, procedures, and essential quality assessment methods at end points that are essential for organoid production applicable at the current technology level.

• Animal cells and systems
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• v.14 no.1
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• pp.11-15
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• 2010

Long-term working memory (LTWM) is a subdivision concept of working memory and indicates the enhancement of performance in a working memory task. LTWM has been shown in humans who have been engaged in a specific task requiring working memory over a long time. However, there is very little understanding of the exact mechanism of LTWM because of limitations of experimental methods in human studies. We have modified the standard T-maze task, which is used to test working memory in mice, to demonstrate LTWM in an animal model. We observed an enhancement of performance by repeated experience with the same working memory load in mice, which can be regarded as an LTWM. This effect seems to depend on the condition wherein a delay was given. This task may be a good experimental protocol to assess LTWM in animal studies.

• Journal of Astronomy and Space Sciences
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• v.28 no.4
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• pp.345-354
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• 2011

Earth acquisition is to solve when earth can be visible from satellite after Sun acquisition during launch and early operation period or on-station satellite anomaly. In this paper, the algorithm and test result of the Communication, Ocean and Meteorological Satellite (COMS) Earth acquisition are presented in case of on-station satellite anomaly status. The algorithms for the calculation of Earth-pointing attitude control parameters including those attitude direction vector, rotation matrix, and maneuver time and duration are based on COMS configuration (Eurostar 3000 bus). The coordinate system uses the reference initial frame. The constraint calculating available time-slot to perform the earth acquisition considers eclipse, angular separation, solar local time, and infra-red earth sensor blinding conditions. The results of Electronics and Telecommunications Research Institute (ETRI) are compared with that of the Astrium software to validate the implemented ETRI software.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.1966-1971
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• 2004

As the remote sensing satellite technology grows, the acquisition of accurate attitude and position information of the satellite has become more and more important. Due to the data processing limitation of the on-board orbit propagator and attitude determination algorithm, it is required to develop much more accurate orbit and attitude determination, which are so called POD (precision orbit determination) and PAD (precision attitude determination) techniques. The sensor and attitude dynamics simulation takes a great part in developing a PAD algorithm for two reasons: 1. when a PAD algorithm is developed before the launch, realistic sensor data are not available, and 2. reference attitude data are necessary for the performance verification of a PAD algorithm. A realistic attitude dynamics and sensor (IRU and star tracker) outputs simulation considering their physical characteristics are presented in this paper, which is planned to be used for a PAD algorithm development, test and performance verification.

• Animal cells and systems
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• v.13 no.3
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• pp.267-274
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• 2009

The dissociative culture technique of Aplysia neuron is one of the key methods that have been used for studies of cellular and molecular mechanisms of neuronal functioning. However, despite the advantages this method offers as an experimental model, its technical efficiency has had room for improvement. In this study, we examined certain putative factors that might affect the culture quality. The effects of neuronal damage induced by physical injuries, heat shock, and surface protein degradation were evaluated along with the correlation between the culture quality and animal behavior. As a result, we found that physical injury can be a critical factor that affects culture quality, whereas the heat shock and surface protein degradation had negligible effect on it. In addition, we discovered that siphon retraction time was not a good measurement for healthy neurons. Based on these findings, we suggest here an improved method in which the degree of physical injury is reduced by means of multiple protease treatment.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.530-533
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• 2005

A raw signal simulator for synthetic aperture radar (SAR) is a useful tool for the design and implementation of SAR system. Also, in order to analyze and verify the developed SAR processor, the raw signal simulator is required. Moreover, there is the need for a test system to help designing new SAR sensors and mission of SAR system. The derived parameters of the SAR simulator also help to generate accurate SAR processing algorithms. Although the ultimate purpose of this research is to presents a general purpose SAR simulator, this paper presents a SAR simulator in frequency domain at the first step. The proposed simulator generates the raw signal by changing various simulation parameters such as antenna parameters, modulation parameters, and sampling parameters. It also uses the statistics from an actual SAR image to imitate actual physical scattering. This paper introduces the procedures and parameters of the simulator, and presents the simulation results. Experiments have been conducted by comparing the simulated raw data with original raw SAR image. In addition, the simulated raw data have been verified through commercial SAR processing software.