• Journal of the Society of Disaster Information
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• v.5 no.2
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• pp.50-73
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• 2009

This paper is about the establishment of "Initial Response System." Initial response system is most important and should be treated urgently among all preparations for chemical terrorism. The objects of Initial response system are to protect civilians and the first responder who are exposed directly to chemical terrorism. Therefore, this paper suggests two main issues about Initial response system. One is to prepare immediate and exact information service system which assures the safety and survival of exposed people. The other is to build Scene Response System integrated with Command-Control Procedure for early finished situation. Compared to United States, overcoming the Chemical Terrorism requires to improve the contents of two categories: Counter Citizen Response part and Initial Scene Response part. For Counter citizen response part' s sake, the web-sites of Response leader agencies for searching information about chemical terrorism should be modified specifically. These web-sites have to be re-organized in detail. The existing Information service system which has been vaguely informed as "CBRNE Accident" needs to be divided as "CBRNE Accident" and "WMD terrorism." Further, each of them should be specialized in "Chemical', "Biological", and "Radiological" categories. There is a need to rearrange current Emergency Instruction for civilians against chemical terrorism in feasible way. At the same time, it should be applied consistently to all organizations through agreement between experts and related-organizations. For Initial Scene Response part's sake, "Initial scene response procedure (SOP)" and "Operational conception" should be produced through Simulated Exercises and workshops of all organizations related with initial response. These organizations have to cooperate with Ministry of Environment which is the main leader Agency as the center. Next, there is a need to develop a technology and Scene Response Equipments, and to standardize the response equipments which consider the capability of First Responders for chemical terrorism. Especially, improving capability of equipments is required to overcome the vulnerability of Scene Response Equipments.

• Journal of Mechanical Science and Technology
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• v.15 no.9
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• pp.1226-1239
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• 2001

Rotating machinery often encounters excessive vibration due to various excitation sources. Among others, the synchronous excitation due to rotating unbalance and initial deformation is acknowledged to be one of the major sources of vibration in rotor-bearing systems. In this paper, a synchronous response analysis method in the presence of the initial deformation is proposed to investigate the peculiar effect of the initial deformation on the response of general flexible rotor-bearing systems with rotational speed dependency and the anisotropy. Experiments are performed and compared with computational results to verify the proposed analysis method. Two numerical examples are also provided to illustrate the characteristics of the synchronous response of general rotor-bearing systems due to the initial deformation.

• Structural Engineering and Mechanics
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• v.17 no.2
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• pp.267-279
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• 2004

This paper presents an improved Monte Carlo simulation for the probabilistic determination of initial cable forces of cable-stayed bridges under dead loads using the response surfaces method. A response surface (i.e. a quadratic response surface without cross-terms) is used to approximate structural response. The use of the response surface eliminates the need to perform a deterministic analysis in each simulation loop. In addition, use of the response surface requires fewer simulation loops than conventional Monte Carlo simulation. Thereby, the computation time is saved significantly. The statistics (e.g. mean value, standard deviation) of the structural response are calculated through conventional Monte Carlo simulation method. By using Monte Carlo simulation, it is possible to use the existing deterministic finite element code without modifying it. Probabilistic analysis of a truss demonstrates the proposed method' efficiency and accuracy; probabilistic determination of initial cable forces of a cable-stayed bridge under dead loads verifies the method's applicability.

• Magazine of the Korean Society of Agricultural Engineers
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• v.41 no.4
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• pp.77-85
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• 1999

In this study, a computer program considering initial imperfection of axisymmetric reinforced concrete shell which plastic deformation by large external loading was developed . Initial imperfection of dome was assumed as 'dimple type' which can be expressed as Wi=(Wo/h)(1-x$^2$)$^3$. The developed model applied to the analysis of dynamic response of axisymmetric reinforced concrete shell when it has initial imperfection. The initial imperfection of 0.0, -5.0, and 5cm and steel and steel layer ratio 0,3, and 5% were tested for numerical examples . The results can be summarized as follows ; 1. Dynmaic response of vertical deflection at dome crown showed slow increased if it has not inital imperfection . But the response showed relatively high amplitude when initial imperfection was inner directed (opposite direction to loading). Similar trends also appeared for different steel layer ratios. 2. Dynamic responses of radial displacement at the junction of dome and wall showed the highest amplitude when initial imperfection was inward directed (opposite direction to loading). The lowest amplitude occurred when initial imperfection was outward directed (same direction to loading). Vibration period also delayed for inward directed initial imperfection . These trends were obvious as steel layer ratio increasing. 3. The effects of imperfection for the dynamic response of radial displacement a the center of wall scarely appeared. The effects of initial imperfection of dome on the dynmaic response of the wall can be neglected. 4. Effect of steel on the dynmic response of axisymmetric shell structure was great when initial imperfection did not exist. And the effect of direction of initial imperfection (inward or outward) did not show big difference.

• Journal of Institute of Control, Robotics and Systems
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• v.19 no.4
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• pp.285-289
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• 2013

In switching from the track-seeking or track-jumping control mode to track-following control mode in hard disk drives or optical disk drives, initial values of the feedback controller are tuned to improve the transient response. In general, all the initial values of the controller have been compensated for this purpose. In this paper, by partially compensating initial values of digital controllers, we achieve a good performance of the transient response. In the proposed method for IVC (Intial Value Compensation), LMIs (Linear Matrix Inequalities) are used, which includes conditions for improving the performance of the transient response such as reducing a tracking error and control efforts. We obtain optimal initial values of the controller by solving an optimization problem with constraints represented by only one LMI. Although initial values of the controller are partially compensated, we can show that not only a sufficient performance of the transient response is obtained but also control efforts are diminished. The feasibility of the method is verified by simulation studies.

• Magazine of the Korean Society of Agricultural Engineers
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• v.42 no.3
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• pp.114-120
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• 2000

In this study a computer program considering initial imperfection of wall of axisymmetric reinforced concrete shell which show plastic deformation by large external loading is developed. initial imperfection of wall of axisymmetric reinforced concrete shell is assumed as sinusoidal curve expressed as {{{{ {W }_{i } }}}}={{{{ {W}_{0 } }}}}sin (n$\pi$y/$\ell$)y. The developed program is applied to the analysis of the dynamic response of axisymmetric reinforced concrete shell when the wall has initial imperfection. The initial imperfection of 0.0 -5.0, and 5cm and steel ratio 0.3, and 5% are tested for numerical examples. The effects of the wall initial imperfection and steel ratio on the dynamic response of the axisymmetric reinforced concrete shell are analysed, It is shown that the direction of the initial imperfection is very important factors for determining the dynamic response.

• Structural Engineering and Mechanics
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• v.72 no.1
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• pp.71-81
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• 2019

The objective of this paper is to develop a size-dependent nonlinear model of beams for fluid-conveying nanotubes with an initial deflection. The nonlinear frequency response of the nanotube is analysed via an Euler-Bernoulli model. Size influences on the behaviour of the nanosystem are described utilising the nonlocal strain gradient theory (NSGT). Relative motions at the inner wall of the nanotube is taken into consideration via Beskok-Karniadakis model. Formulating kinetic and elastic energies and then employing Hamilton's approach, the nonlinear motion equations are derived. Furthermore, Galerkin's approach is employed for discretisation, and then a continuation scheme is developed for obtaining numerical results. It is observed that an initial deflection significantly alters the frequency response of NSGT nanotubes conveying fluid. For small initial deflections, a hardening nonlinearity is found whereas a softening-hardening nonlinearity is observed for large initial deflections.

• Journal of Korean Neurosurgical Society
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• v.66 no.5
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• pp.562-572
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• 2023

Objective : Bevacizumab is a feasible option for treating cerebral radiation necrosis (RN). We investigated the clinical outcome of RN after treatment with bevacizumab and factors related to the initial response and the sustained effect. Methods : Clinical data of 45 patients treated for symptomatic RN between September 2019 and February 2021 were retrospectively collected. Bevacizumab (7.5 mg/kg) was administered at 3-week intervals with a maximum four-cycle schedule. Changes in the lesions magnetic resonance image (MRI) scans were examined for the response evaluation. The subgroup analysis was performed based on the initial response and the long-term maintenance of the effect. Results : Of the 45 patients, 36 patients (80.0%) showed an initial response, and eight patients (17.8%) showed delayed worsening of the corresponding lesion. The non-responders showed a significantly higher incidence of diffusion restriction on MRI than the responders (100.0% vs. 25.0%, p<0.001). The delayed worsening group showed a significantly higher proportion of glioma pathology than the maintenance group (87.5% vs. 28.6%, p=0.005). Cumulative survival rates with sustained effect were significantly higher in the groups with non-glioma pathology (p=0.019) and the absence of diffusion restriction (p<0.001). Pathology of glioma and diffusion restriction in MRI were the independent risk factors for non-response or delayed worsening after initial response. Conclusion : The initial response of RN to bevacizumab was favorable, with improvement in four-fifths of the patients. However, a certain proportion of patients showed non-responsiveness or delayed exacerbations. Bevacizumab may be more effective in treating RN in patients with non-glioma pathology and without diffusion restriction in the MRI.

• The korean journal of orthodontics
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• v.24 no.4 s.47
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• pp.799-817
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• 1994

The purpose of this study was to evaluate the initial skeletal pattern and growth change of whom had responsed well to chincap therapy. 93 patients seleted for this study were in mixed dentition and treated with chincap for more than 2 years. And 54 subjects were selected from these total samples and classified into two groups by the improvement of four measurements : ANB difference, APDI, Wits appraisal, and AF-BF. One was good response group which consisted of 26 children and the other was poor response group with 19 patients. Various measures of the craniofacial structure in the initial lateral cephalograms and the annual increments were calculated and analyzed by comparing two groups with t-test. The results were as follows : 1. Good response group had more horizontal growth pattern in initial stage of treatment than poor response group, and the contributing factors of this result were anterior posterior facial height ratio, gonial angle, lower genial angle and SN-mandibular plane angle. 2. The maxilla was positioned more anteriorly in good response group. 3. The amounts of vertical growth of maxilla was smaller but the horizontal growth of maxilla was larger in good response group. 4. The mandible rotated more infero-posteriorly in good response group. 5. The good response group had more vertical growth pattern of mandibular condyle.

• Environmental Engineering Research
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• v.25 no.4
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• pp.488-497
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• 2020

The present study investigates the feasibility of nitrogenous heterocyclic compounds (NHCs) (Pyridine-Quinoline) degradation by catalytic wet peroxidation (CWPO) in the presence of nanoscale zerovalent iron supported on granular activated carbon (nFe⁰/GAC) using statistical optimization technique. Response surface methodology (RSM) in combination with Box-Behnken design (BBD) was used to optimize the process parameters of CWPO process such as initial pH, catalyst dose, hydrogen peroxide dose, initial concentration of pyridine (Py) and quinolone (Qn) were chosen as the main variables, and total organic carbon (TOC) removal and total Fe leaching were selected as the investigated response. The optimization of process parameters by desirability function showed the ~85% of TOC removal with process condition of initial solution pH 3.5, catalyst dose of 0.55 g/L, hydrogen peroxide concentration of 0.34 mmol, initial concentration of Py 200 mg/L and initial concentration of Qn 200 mg/L. Further, for TOC removal the analysis of variance results of the RSM revealed that all parameter i.e. initial pH, catalyst dose, hydrogen peroxide dose, initial concentration of Py and initial concentration of Qn were highly significant according to the p values (p < 0.05). The quadratic model was found to be the best fit for experimental data. The present study revealed that BBD was reliable and effective for the determination of the optimum conditions for CWPO of NHCs (Py-Qn).