• Journal of Korean Neurosurgical Society
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• 제48권3호
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• pp.230-235
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• 2010

Objective : The aim of this study is to compare the surgical outcome of the initial and recent surgical cases, during our 15-years experience, in terms of the surgical strategies and the prognostic factors for surgically remediable epilepsy. Methods : We retrospectively reviewed and compared the surgical outcomes between the initial 256 (Group I) and recent 139 (Group II) patients according to the time period of operation for a total of 518 consecutive epilepsy surgeries at our institution since 1992. The patients of the middle intermediate period, which were subjected to changed surgical strategies, were excluded. Results : The surgical outcome data from the initial and recent groups showed a much improved outcome for patients who underwent temporal lobe epilepsy (TLE) surgery over time. The number of patients with a good outcome (Engel class I-II) was much increased from 87.7% (178 TLE cases of Group I) to 94.8% (79 TLE cases of Group II) and this was statistically significant (p = 0.0324) on univariate analysis. Other remarkable changes were the decreased performance of intracranial invasive studies from 43.5% in Group I to 30.9% in Group II due to the advanced neuroimaging tools. The strip/grid ratio was reduced from 131/32 in Group I to 17/25 in Group II, because of a markedly reduced mesial TLE surgery and an increased extratemporal epilepsy surgery. Conclusion : Our results show that surgical outcome of epilepsy surgery has improved over time and it has shown to be efficient to control medically intractable epilepsy. Appropriate patient selection, comprehensive preoperative assessments and more extensive resection are associated with good postoperative outcomes.

• 한국운동역학회지
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• 제28권3호
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• pp.181-185
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• 2018

Objective: The purpose of this study was to investigate the effect of types of drive-in initial steps in basketball on technical factors, to provide basic information for the enhancement of basketball skill. Method: Ten men (age: $24.70{\pm}2.26years$; height: $181.00{\pm}5.72cm$; weight: $75.70{\pm}8.23kg$; career length: $10.00{\pm}3.59years$), each with a career length of over five years and no history of injury to the lower extremities within the prior six months, participated in this study. They were asked to perform four types of drive-in movements at $35{\sim}60^{\circ}$, wearing their own shoes, after running from a start line 5 m away and catching a basketball passed by an expert passer. The drive-in movements were measured by eight infrared cameras (Oqus 300, Qualisys, Sweden). Collected raw data were used to calculate total initial step time, displacement, velocity, center of mass (COM) height, and COM velocity. Results: Total initial step displacement and velocity of cross drive-ins (JC, SC) were greater than that of direct drive-ins (JD, SD; p < .05). COM velocity of cross drive-ins (JC, SC) was also greater than that of direct drive-ins (JD, SD; p < .05). Conclusion: Our results indicated that cross drive-ins, regardless of stop step type, are more effective than direct drive-ins. This is because cross drive-ins are technically bold due to less influence from walking violations and double dribble rules in basketball. However, using one-sided movement is too difficult to play in competitive game; therefore, basketball players should develop the ability to choose appropriate movement frequency.

• 한국철학논집
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• 제31호
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• pp.173-202
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• 2011

엘리아데는 애초의 성스러움이 저절로 드러나는 것을 성현(聖顯)이라고 하였는데, 성현이 일어나는 대상이나 장소는 질의 전환을 이루어 그 자체가 성스러워진다. 사람들은 태초의 성스러움을 되살리기 위해 최초로 성스러움이 일어난 그 순간을 재현하고자 하여 원형의 순간과 동일한 시간에 동일한 장소에서 동일한 행위를 통해 성을 재현하려고 하였다. 이 논문에서 주목한 것은 성스러움이 드러나는 구체적 장소이다. 천제가 세운 지상의 도읍으로 신이 사는 영역이며, 지상과 천상을 이어주는 역할을 하는 우주산의 특성을 갖춘 곤륜, 하늘과 지상을 이어주는 매개인 하늘사다리의 역할을 하는 건목, 종교적 인간이 성스러운 실재적 공간에서 살고 싶은 욕망을 드러내며 성스러운 공간을 통해 신적 존재나 조상과 교류함으로써 태초의 순수한 영혼으로 회귀할 수 있는 공간인 도시와 종묘는 모두 고대 중국에서 볼 수 있는 성이 드러나는 구체적 공간이라고 할 수 있다.

• 대한화장품학회지
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• 제39권1호
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• pp.55-63
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• 2013

경피흡수 증진의 수단으로 나노에멀젼의 화장품 응용이 관심의 대상이 되고 있다. 본 연구에서는 저에너지 유화법으로 제조된 나노에멀젼 구성 원료들의 조성을 달리하여 안정성을 확인해 보고자 하였다. 시간 경과에 따른 나노에멀젼의 입자 크기 측정을 통한 안정성 실험 결과, 폴리올을 수상에 첨가한 경우 에탄올상 첨가에 비해 안정성이 크게 증가하였다. 에탄올상의 수상에 대한 첨가속도는 입자 크기나 안정성에 큰 영향이 없었다. 오일의 종류에 따라서도 안정성에는 영향이 없었으나 초기에 형성되는 입자 크기는 오일의 분자량과 polarity에 상관관계를 보이는 것으로 생각되었다. 폴리올의 종류에 따른 안정성과 초기 입자 크기는 1,2 헥산디올을 제외하고는 유사한 경향을 보였다. 오일과 계면활성제 농도 변화는 제조된 나노에멀젼의 초기 입자 크기에는 영향을 주었으나 시간 경과에 따른 변화는 없었다. 에탄올의 농도 변화는 초기 입자 크기와 안정성에 큰 영향을 미치는 것으로 관찰되었다.

• Journal of Trauma and Injury
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• 제18권2호
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• pp.119-126
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• 2005

Background: Blunt thoracic trauma in children has a high morbidity and mortality. In this study, we assessed the significance of the injury pattern, mechanism and initial status in emergency department on severity and prognosis in pediatric blunt thoracic trauma patients. Method: We retrospectively reviewed medical records and chest X-ray and CT images of 111 pediatric blunt thoracic trauma patients from October 2000 to June 2005. Data recorded age, gender, season, injury mechanism, injury pattern, associated injury, length of hospital stay and cause of death. Result: Of all 111 patients, 68 patients were injured by motor vehicle accidents, 30 were falls, 5 were motorcycle accidents, 3 were sports accidents and 5 were miscellaneous. In thoracic trauma, single injury of lung contusion were 35 patients and 32 patients had multiple thoracic injuries. Hospital stay in school age group were longer than preschool age group. The causes of death were brain injury in 9, respiratory distress in 4, and hypovolemic shock in 2 patients. Emergently transfused and mechanically ventilated patients had higher mortality rates than other patients. Patients required emergency operation and patients with multiple thoracic injuries had higher mortality rates. Conclusion: In this study, patients with combined injury, emergency transfusion, mechanical ventilation, emergency operation, multiple injuries in chest X-ray had higher mortality rates. Therefore in these pediatric blunt thoracic trauma patients, accurate initial diagnosis and proper management is required.

• Journal of Gastric Cancer
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• 제12권3호
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• pp.173-178
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• 2012

Purpose: To report the initial clinical experience with single-incision laparoscopic gastric wedge resection for submucosal tumors. Materials and Methods: The medical records of 10 patients who underwent single-incision laparoscopic gastric wedge resection between July 2009 and March 2011 were reviewed retrospectively. The demographic data, clinicopathologic and surgical outcomes were assessed. Results: The mean tumor size was 2.5 cm (range, 1.2~5.0 cm), and the tumors were mostly located on the anterior wall (4/10) or along the greater curvature (4/10), of the stomach. Nine of ten procedures were performed successfully, without the use of additional trocars, or conversion to laparotomy. One patient underwent conversion to multiport laparoscopic surgery, to get simultaneous cholecystectomy safely. The mean operating time was 66.5 minutes (range, 24~132 minutes), and the mean postoperative hospital stay was 5 days (range, 4~7 days). No serious perioperative complications were observed. Of the 10 submucosal tumors, the final pathologic report revealed 5 gastrointestinal stromal tumors, 4 schwannomas, and 1 heterotopic pancreas. Conclusions: Single-incision laparoscopic gastric wedge resection for gastric submucosal tumors is feasible and safe, when performed by experienced laparoscopic surgeons. This technique provides favorable cosmetic results, and also short hospital stay and low morbidity, in carefully selected candidates.

• 한국물환경학회지
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• 제23권3호
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• pp.348-355
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• 2007

We investigated temporal changes of composition, habitat area, growth rate and elements content of hydrophytes at the artificial vegetation island (AVI) in Kyungan Stream within Lake Paldang. We also assessed nutrient removal rate through cutting off the emergent part of hydrophytes. The kinds of hydrophytes have increased from four species (P. australis, P. japonica, T. angustifolia and the Z. latifolia) at initial stage of installation to more than 29 species for 6-year operation. P. japonica was most dominant species at the AVI in 2006. The habitat area of have increased about 2.5 times compared to the initial planting area, occupying 63% of AVI's vegetation area. The incoming species of S. fluviatilis and B. frondosa have adapted successively and expanded habitat area in the AVI. The relative growth rate of P. japonica and P. australis was highest in spring sprouting period. Their hights and weights have increased until summer, by the time they were cutting off the emergent part. They started regrowth immediately after cutting and continued to grow until September and withered away in November. The carbon contents of P. japonica and P. australis have increased during growth phase, on the contrary, the nitrogen and phosphorus contents have decreased. By cutting off and removing the emergent part (leaves and branches) of hydrophytes twice from AVI, $17.6gN/m^2/y$ of nitrogen and $1.3gP/m^2/y$ of phosphorus was removed from AVI in 2006.

• Nuclear Engineering and Technology
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• 제38권3호
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• pp.231-238
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• 2006

Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.

• Journal of Korean Neurosurgical Society
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• 제56권1호
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• pp.34-41
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• 2014

Objective : The purpose of this study was to describe the clinical characteristics, treatment outcomes, and prognostic factors in patients with brain abscesses treated in a single institute during a recent 10-year period. Methods : Fifty-one patients with brain abscesses who underwent navigation-assisted abscess aspiration with antibiotic treatment were included in this study. Variable parameters were collected from the patients' medical records and radiological data. A comparison was made between patients with favorable [Glasgow Outcome Scale (GOS) ${\geq}4$] and unfavorable (GOS <4) outcomes at discharge. Additionally, we investigated the factors influencing the duration of antibiotic administration. Results : The study included 41 male and 10 female patients with a mean age of 53 years. At admission, 42 patients (82%) showed either clear or mildly disturbed consciousness (GCS ${\geq}13$) and 24 patients (47%) had predisposing factors. The offending microorganisms were identified in 25 patients (49%), and Streptococcus species were the most commonly isolated bacteria (27%). The mean duration of antibiotic administration was 42 days. At discharge, 41 patients had a favorable outcome and 10 had an unfavorable outcome including 8 deaths. The decreased level of consciousness (GCS <13) on admission was likely associated with an unfavorable outcome (p=0.052), and initial hyperglycemia (${\geq}140mg/dL$) was an independent risk factor for prolonged antibiotic therapy (p=0.032). Conclusion : We found that the level of consciousness at admission was associated with treatment outcomes in patients with brain abscesses. Furthermore, initial hyperglycemia was closely related to the long-term use of antibiotic agents.

• Radiation Oncology Journal
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• 제37권3호
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• pp.156-165
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• 2019

Purpose: Prophylactic cranial irradiation (PCI) is a standard treatment for limited-stage small cell lung cancer (LS-SCLC) showing a response to initial treatment, but many patients do not receive PCI due to comorbidities or refusal. This study aims to define the patient group for whom PCI can be omitted with minimal risk. Materials and Methods: Patients with LS-SCLC who underwent radiotherapy with curative aim at our institution between January 2004 and December 2015 were retrospectively reviewed. Patients who did not receive PCI were evaluated for brain metastasis-free survival (BMFS), progression-free survival (PFS), overall survival (OS), and prognostic factors for survival, and treatment outcomes were compared with a patient cohort who received PCI. Results: A total of 350 patients achieved a response following thoracic radiotherapy, and 190 of these patients did not receive PCI. Stage I-II and a complete response (CR) to initial therapy were good prognostic factors for BMFS and OS on univariate analysis. Patients with both stage I-II and a CR who declined PCI showed comparable 2-year BMFS to those who received PCI (92% vs. 89%). In patients who achieved CR, PCI did not significantly improve OS or PFS. Conclusion: There should be less concern about omitting PCI in patients with comorbidities if they have stage I-II or a CR, with brain metastasis control being comparable to those patients who receive PCI.