• Title/Summary/Keyword: Initial Design Method

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Effects of Feeding Barley Naturally Contaminated with Fusarium Mycotoxins on Growth Performance, Nutrient Digestibility, and Blood Chemistry of Gilts and Growth Recoveries by Feeding a Non-contaminated Diet

  • Kong, C.;Shin, S.Y.;Park, C.S.;Kim, B.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.5
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    • pp.662-670
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    • 2015
  • The objectives of this study were to investigate the effects of feeding barley naturally contaminated with Fusarium mycotoxins on growth performance, vulva swelling, and digestibility of dry matter, organic matter, and crude protein of gilts and the recovery of gilts fed normal diets immediately after the exposure to contaminated diets by measuring growth performance and vulva swelling. In Exp. 1, four diets were prepared to contain 0%, 15%, 30%, or 45% contaminated barley containing 25.7 mg/kg deoxynivalenol and $26.0{\mu}g/kg$ zearalenone. Sixteen gilts with an initial body weight (BW) of 33.3 kg (standard deviation = 3.0) were individually housed in a metabolism crate and assigned to 4 diets with 4 replicates in a randomized complete block design based on BW. During the 14-d feeding trial, individual BW and feed consumption were measured weekly and the vertical and horizontal lengths of vulva were measured every 3 d. From d 10, feces were collected by the maker-to-marker method for 4 d. Blood samples were collected on d 14. During the overall period, the average daily gain, average daily feed intake, and gain:feed of pigs linearly decreased (p<0.01) as the dietary concentration of contaminated barley increased. However, the digestibility of crude protein was linearly increased (p = 0.011) with the increasing amounts of contaminated barley. Increasing dietary Fusarium mycotoxin concentrations did not influence vulva size, blood characteristic as well as immunoglobulin level of pigs. In the Exp. 2, a corn-soybean meal-based diet was formulated as a recovery diet. Pigs were fed the recovery diet immediately after completion of the Exp. 1. During the 14-d of recovery period, the individual BW and feed consumption were measured weekly and the vertical and horizontal length of vulva were measured every 3 d from d 0. On d 7, the feed intake of pigs previously fed contaminated diets already reached that of pigs fed a diet with 0% contaminated barley and no significant difference in growth performance among treatments was observed during d 7 to 14 of the recovery period. In conclusion, increasing levels of mycotoxins in diets linearly decreased the growth performance of pigs, and these damages can be recovered in 7 d after the diet was replaced with a normal diet. The vulva size, blood characteristic, immune responses were not affected by increasing level of contaminated barley in the diets fed to pigs.

Shear Strength Characteristics of Geo - Soluble - Materials (용해재료가 포함된 지반의 전단강도 특성)

  • Tran, M. Khoa;Park, Jung-Hee;Byun, Yong-Hoon;Shin, Ho-Sung;Lee, Jong-Sub
    • Journal of the Korean Geotechnical Society
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    • v.27 no.12
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    • pp.17-25
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    • 2011
  • A fabric of soil media may change due to certain factors such as dissolution of soluble particles, desiccation, and cementation. The fabric changes affect the mechanical behavior of soils. The purpose of this study is to investigate the effects of geo-material dissolution on shear strength. Experiments and numerical simulations are carried out by using a conventional direct shear and the discrete element method. The dissolution specimens are prepared with different volumetric salt fraction in sand soils. The dissolution of the specimens is implemented by saturating the salt-sand mixtures at different confining stresses in the experimental study or reducing the sizes of soluble particles in the numerical simulations. Experimental results show that the angle of shearing resistance decreases with the increase in the soluble particle content and the shearing behavior changes from dilative to contractive behavior. The numerical simulations exhibit that macro-behavior matches well with the experimental results. From the microscopic point of view, the particle dissolution produces a new fabric with the increase of local void, the reduction of contact number, the increase of shear contact forces, and the anisotropy of contact force chains compared with the initial fabric. The shearing behavior of the mixture after the particle dissolution is attributed to the above micro-behavior changes. This study demonstrates that the reduction of shearing resistance of geo-material dissolution should be considered during the design and construction of the foundation and earth-structures.

Use of Hydrogen Peroxide with Ozone to Simultaneously Reduce MIB and Quench Ozone Residual in Existing Water Treatment Plants Sourcing Water from the Han River (한강을 원수로 하는 오존/과산화수소 고도정수처리공정에서의 MIB제거 및 잔류오존 농도에 관한 연구)

  • McAdams, Stephen R.;Koo, Bon Jin;Jang, Myung Hoon;Lee, Sung Kyoo
    • Journal of Korean Society on Water Environment
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    • v.28 no.5
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    • pp.704-716
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    • 2012
  • This paper provides a detailed account of pilot testing conducted at South Lake Tahoe (California), the Ddukdo (Seoul) water treatment plant (WTP) and the Bokjung (Seongnam) WTP between February, 2010, and February, 2012. The objectives were first, to characterize the reactions of ozone with hydrogen peroxide (Peroxone) for Han River water following sand filtration, second to determine empirical ozone and hydrogen peroxide doses to remove a taste-and-odor surrogate 2-methylisoborneol (MIB) using an advanced oxidation process (AOP) configuration and third, to determine the optimum dosing configuration to reduce residual ozone to a safe level at the exit of the process. The testing was performed in a real-time plant environment at both low- and high seasonal water temperatures. Experimental results including ozone decomposition rates were dependent on temperature and pH, consistent with data reported by other researchers. MIB in post-sand-filtration water was spiked to 40-50 ng/L, and in all cases, it was reduced to below the specified target level (7 ng/liter) and typically non-detect (ND). It was demonstrated that Peroxone could achieve both MIB removal and low effluent ozone residual at ozone+hydrogen peroxide doses less than those for ozone alone. An empirical predictive model, suitable for use by design engineers and operating personnel and for incorporation in plant control systems was developed. Due to a significant reduction in the ozone reaction/decomposition at low winter temperatures, results demonstrate the hydrogen peroxide can be "pre-conditioned" in order to increase initial reaction rates and achieve lower ozone residuals. Results also indicate the method, location and composition of hydrogen peroxide injection is critical to successful implementation of Peroxone without using excessive chemicals or degrading performance.

A study on in-flight acoustic load reduction in launch vehicle fairing by FE-SEA hybrid method (FE-SEA 하이브리드 기법을 이용한 비행 중 발사체 페어링 내부 음향하중 저감에 관한 연구)

  • Choi, Injeong;Park, Seoryong;Lee, Soogab
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.4
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    • pp.351-363
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    • 2020
  • Launch vehicles are subject to airborne acoustic loads during atmospheric flight and these effects become pronounced especially in transonic region. As the vibration due to the acoustic loads can cause malfunction of payloads, it is essential to predict and reduce the acoustic loads. In this study, a complete process has been developed for predicting airborne vibro-acoustic environment inside the payload pairing and subsequent noise reduction procedure employing acoustic blankets and Helmholtz resonators. Acoustic loads were predicted by Reynolds-Averaged Navier-Stokes (RANS) analysis and a semi-empirical model for pressure fluctuation inside turbulent boundary layer. Coupled vibro-acoustic analysis was performed using VA One SEA's Finite Element Statistical Energy Analysis (FE-SEA) hybrid module and ANSYS APDL. The process has been applied to a hammerhead launch vehicle to evaluate the effect of acoustic load reduction and accordingly to verify the effectiveness of the process. The presently developed process enables to obtain quick analysis result with reasonable accuracy and thus is expected to be useful in the initial design phase of a launch vehicle.

The Development of the Simple SHGC Calculation Method in Case of a Exterior Venetian Blind Using the Simulation (시뮬레이션을 이용한 외부 베네시안 블라인드의 약식 SHGC 계산법 개발)

  • Eom, Jae-Yong;Lee, Chung-Kook;Jang, Weol-Sang;Choi, Won-Ki
    • Journal of the Korean Solar Energy Society
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    • v.35 no.2
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    • pp.73-83
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    • 2015
  • When it comes to these buildings for business use, cooling load during summertime was reported to have great importance which, as a result, impressively increased interest in Solar Heat Gain Coefficient (SHGC). Such SHGC is considered to be lowered with the help of colors and functions of glass itself, internal shading devices, insulation films and others but basically, these external shading devices for initial blocking that would not allow solar heat to come in from outside the buildings are determined to be most effective. Of many different external shading devices, this thesis conducted an analysis on Exterior Venetian Blind. As for vertical shading devices, previous researches already calculated SHGC conveniently using concepts of sky-opening ratios. However in terms of the Venetian Blind, such correlation is not possibly applied. In light of that, in order to extract a valid correlation, this study first introduced a concept called shape factor, which would use the breadth and a space of a shade, before carrying out the analysis. As a consequence, the concept helped this study to find a very similar correlation. Results of the analysis are summarized as follows. (1) Regarding SHGC depending on the surface reflectance of a shade, an average of 2% error is observed and yet, the figure can always be ignored when it comes to a simple calculation. (2) As for SHGC of each bearing, this study noticed deviations of 4% or less and in the end, it is confirmed that extraction can be achieved with no more than one correlation formula. (3) When only the shape factor and nothing else is used for finding a correlation formula, the formula with a deviation of approximately 5% or less is what one would expect. (4) Since the study observed slight differences in bearings depending on ranges of the shape factors, it needed to extract a weighted value of each bearing, and learned that the smaller the shape factor, the wider the range of a weighted value. The study now suggests that a follow-up research to extract a simple calculation formula by dealing with all these various inclined angles of shade, solar radiation conditions of each region (the ratio of diffuse radiation to direct radiation and others) as well as seasonal features should be carried out.

Reliability Analysis of Access Door Opening Force Measured with a Digital Force Gauge of a Pressurized Smoke Control Zone and Presentation of Optimum Conditions for the Opening Force (디지털 측정기로 측정된 급기가압 제연구역의 출입문 개방력에 대한 신뢰성 분석 및 최적 조건 제시)

  • Lee, Jae-Ou;Choi, Chung-Seog
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.468-473
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    • 2016
  • The aim of this study was to measure the opening force of an access door of a pressurized smoke control zone and verify the reliability of the opening force. For the access door opening force, the opening load of the access door was measured before and after pressurized air had entered the smoke control zone. The reliability of the measured values was verified using the Anderson Darling's statistical analysis method of the Minitab Program. Because the analyzed P values were greater than 0.05 except for some floors before and after the operation of the smoke control equipment, the opening force was found to have 95% reliability. The normal distribution of the measured values showed no relationship with the operation of the smoke control equipment and the precision of the force gauge was believed to be reliable. The major factors for the optimal design of the pressurized smoke control equipment include the precision and reliability of the force gauge, the correct posture of the measuring person, and the same conditions for access doors. Therefore, a digital force gauge is believed to be suitable for measuring the opening force of the access door of a pressurized smoke control zone. In addition, standardization of the posture of a measuring person, the setup of the initial opening force of an access door, etc., are major variables for effective measurements of the door opening force of an access door.

Implementation of payment settlement system through Cyber Bank for Electronic Commerce (전자상거래용 사이버뱅크의 지불결제시스템 구축)

  • Kim, Moon-Shik;Lee, Eun-Seok
    • The KIPS Transactions:PartD
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    • v.15D no.1
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    • pp.121-130
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    • 2008
  • In line with the enhanced weight and variety of electronic commerce in business activities, new type of payment settlement and banking system which will enable to store, create and transfer values from the existing method of payment settlement is highly required. Cyber Banking system draws strong attention being the solution of there requirements. The existing Cyber Banking system has the difficulty of operation, administration, in addition to the problem of initial facility investment of big amount, resulted from the usage of the current business process. As the existing Cyber Bank system is unable to carry out the function of storing, creating, and transferring values due to the adoption conventional credit card system instead of the application of non-stop payment system between the seller and buyer. As a result, current Cyber Bank system still imply the deficiency of non-performing cash payment function on internet. This paper describes (1) an integrated application process, One Process One Input (OPOI) which is essential for software development of the Cyber Bank, (2) an application process of payment settlement system to be applied to the electronic commerce in Internet. And then, with these for a basis, (3) design and implementation of payment settlement system through CyberBank for Electronic Commerce. Consequently, by means of this suggested process, we could attempt to solve the problem of existing Cyber Bank system and further to explore the possibility of advanced Cyber Banking being the non-stop payment settlement system. The effectiveness of this suggested system has been practically confirmed.

Characteristics of BCNU-loaded PLGA Wafers (BCNU를 함유한 생분해성 PLGA 웨이퍼의 특성분석)

  • 안태군;강희정;이진수;성하수;정제교
    • Polymer(Korea)
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    • v.26 no.5
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    • pp.691-700
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    • 2002
  • Interstitial therapy using biodegradable polymeric device loaded with anticancer agent can deliver the drug to the tumor site at high concentration, resulting in an increase of therapeutic efficacy. 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) is most commonly used as chemotherapeutic agent for brain tumors. The design of implantable device is regarded as an important factor lot the efficient delivery of antitumor agent to targeting site. In order to control the release profile of drug, the release pattern of BCNU with the changes of various dimension and additives was investigated. The PLGA wafers containing 3.85, 10, 20 and 30% of BCNU were prepared in various shape (diameter of 3, 5 and 10 mm, thickness of 0.5, 1 and 2 mm) by direct compression method. In vitro drug release profile of BCNU-loaded PLGA wafers could be controlled by changing the dimension of wafers such as initial drug content, weight, diameter, thickness, volume and surface area of wafers, as well as PLGA molecular weight and additives. Drug release from BCNU-loaded PLGA wafers was facilitated with an increase of BCNU-loading amount or presence of poly(N-vinylpyrrolidone)(PVP) or sodium chloride (NaCl). The effects of various geometric factors and additives on the BCNU release pattern were confirmed by the investigation of mass loss and morphology of BCNU-loaded PLGA wafers.

Mechanical Property and Cell Compatibility of Silk/PLGA Hybrid Scaffold; In Vitro Study (실크/PLGA 하이브리드 지지체의 기계적 물성과 세포친화력; in vitro 연구)

  • Song, Yi-Seul;Yoo, Han-Na;Eum, Shin;Kim, On-You;Yoo, Suk-Chul;Kim, Hyung-Eun;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.35 no.3
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    • pp.189-195
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    • 2011
  • The design of new bioactive scaffolds offering physiologic environment for tissue formation is an important frontier in biomaterials research. In this study, we performed compressive strength, water-uptake ability, and SEM analysis for physical property assessment of 3-D silk/PLGA scaffold, and investigated the adhesion, proliferation, phenotype maintenance, and inflammatory responses of RAW 264.7 and NIH/3T3 for cell compatibility. Scaffolds were prepared by the solvent casting/salt leaching method and their compressive strength and water-uptake ability were excellent at 20 wt% silk content. Result of cell compatibility assay showed that inflammatory responses distinctly decreased, and initial adhesion and proliferation were maximized at 20 wt% silk content. In conclusion, we suggest that silk/PLGA scaffolds may be useful to tissue engineering applications.

Uncoupled Solution Approach for treating Fluid-Structure Interaction due to the Near-field Underwater Explosion (근거리 수중폭발에 따른 유체-구조 상호작용 취급을 위한 비연성 해석방법)

  • Park, Jin-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.10
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    • pp.125-132
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    • 2019
  • Because the water exposed to shock waves caused by an underwater explosion cannot withstand the appreciable tension induced by the change in both pressure and velocity, the surrounding water is cavitated. This cavitating water changes the transferring circumstance of the shock loading. Three phenomena contribute to hull-plate damage; initial shock loading and its interaction with the hull plate, local cavitation, and local cavitation closure then shock reloading. Because the main concern of this paper is local cavitation due to a near-field underwater explosion, the water surface and the waves reflected from the sea bottom were not considered. A set of governing equations for the structure and the fluid were derived. A simple one-dimensional infinite plate problem was considered to verify this uncoupled solution approach compared with the analytic solution, which is well known in this area of interest. The uncoupled solution approach herein would be useful for obtaining a relatively high level of accuracy despite its simplicity and high computational efficiency compared to the conventional coupled method. This paper will help improve the understanding of fluid-structure interaction phenomena and provide a schematic explanation of the practical problem.